Platelet-derived growth factor-BB induces cystathionine Iγ-lyase expression in rat mesangial cells via a redox-dependent mechanism

British Journal of Pharmacology

Volumn 166, Issue 8, 2012, Pages 2231-2242

  Hassan, Mohamed I ^a   Boosen, Meike ^a   Schaefer, Liliana ^a   Kozlowska, Jowita ^a   Eisel, Florian ^a   Von Knethen, Andreas ^a   Beck, Martina ^a   Hemeida, Ramadan A M ^b   El Moselhy, Mohamed A M ^c   Hamada, Farid M A ^b   Beck, Karl Friedrich ^a   Pfeilschifter, Josef ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b Al Azhar University   (Egypt)

^c Minia University   (Egypt)

Author keywords

cystathionine I lyase; Mesangial cells; nuclear erythroid 2 related factor 2; platelet derived growth factor; reactive oxygen species; redox

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; CHLORINE DERIVATIVE; CYSTATHIONINE GAMMA LYASE; DIPHENYLENE IODONIUM CHLORIDE; EBSELEN; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR BB; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONTROLLED STUDY; CYSTATHIONINE GAMMA LYASE GENE; ENZYME ACTIVITY; ENZYME REGULATION; GENE SILENCING; KNOCKOUT MOUSE; MALE; MESANGIUM CELL; MOUSE; NONHUMAN; NRF2 GENE; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; REVIEW; UPREGULATION; WILD TYPE;

ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; CYSTATHIONINE GAMMA-LYASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLOMERULONEPHRITIS; ISOANTIBODIES; MACROPHAGES; MESANGIAL CELLS; MICE; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; PROTO-ONCOGENE PROTEINS C-SIS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SPLEEN;

EID: 84864444666     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.01949.x     Document Type: Review

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