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Volumn 110, Issue 3, 2009, Pages 137-145

B cell activating factor, its role in autoimmunity, and targeting in autoimmune diseases

Author keywords

Autoimmunity; B cells; BAFF

Indexed keywords

B CELL ACTIVATING FACTOR;

EID: 70349769212     PISSN: 00069248     EISSN: 13360345     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (28)

References (92)
  • 1
    • 70349760930 scopus 로고    scopus 로고
    • Autoimmunity
    • Buc M (Ed). Bratislava; Comenius University Press
    • Buc M. Autoimmunity. 205-217. In: Buc M (Ed). Basic and clinical immunology. Bratislava; Comenius University Press, 2008.
    • (2008) Basic and clinical immunology , pp. 205-217
    • Buc, M.1
  • 2
    • 33750209982 scopus 로고    scopus 로고
    • Targeting BAFF: immunomodulation for auto immune diseases and lymphomas
    • Sutherland AP et al. Targeting BAFF: immunomodulation for auto immune diseases and lymphomas. Pharmacol Ther 2006; 112 (3): 774-786.
    • (2006) Pharmacol Ther , vol.112 , Issue.3 , pp. 774-786
    • Sutherland, A.P.1
  • 3
    • 0035860559 scopus 로고    scopus 로고
    • An essential role for BAFF in the normal deve lopment of B cells through a BCMA-independent pathway
    • Schiemann B et al. An essential role for BAFF in the normal deve lopment of B cells through a BCMA-independent pathway. Science 2001; 293 (5537): 2111-2114.
    • (2001) Science , vol.293 , Issue.5537 , pp. 2111-2114
    • Schiemann, B.1
  • 4
    • 0142188050 scopus 로고    scopus 로고
    • Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice
    • Rahman ZS et al. Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice. J Exp Med 2003; 198 (8): 1157-1169.
    • (2003) J Exp Med , vol.198 , Issue.8 , pp. 1157-1169
    • Rahman, Z.S.1
  • 5
    • 9144244817 scopus 로고    scopus 로고
    • Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function
    • Gorelik L et al. Cutting edge: BAFF regulates CD21/35 and CD23 expression independent of its B cell survival function. J Immunol 2004; 172 (2): 762-766.
    • (2004) J Immunol , vol.172 , Issue.2 , pp. 762-766
    • Gorelik, L.1
  • 6
    • 3342877696 scopus 로고    scopus 로고
    • BLyS-an essential survival factor for B cells: basic biolo gy, links to pathology and therapeutic target
    • Baker KP. BLyS-an essential survival factor for B cells: basic biolo gy, links to pathology and therapeutic target. Autoimmun Rev 2004; 3 (5): 368-375.
    • (2004) Autoimmun Rev , vol.3 , Issue.5 , pp. 368-375
    • Baker, K.P.1
  • 7
    • 4043075603 scopus 로고    scopus 로고
    • TNF family member B cell-activating factor (BAFF) receptor-dependent and-independent roles for BAFF in B cell physiolo gy
    • Sasaki Y et al. TNF family member B cell-activating factor (BAFF) receptor-dependent and-independent roles for BAFF in B cell physiolo gy. J Immunol 2004; 173 (4): 2245-2252.
    • (2004) J Immunol , vol.173 , Issue.4 , pp. 2245-2252
    • Sasaki, Y.1
  • 8
    • 16844364286 scopus 로고    scopus 로고
    • The BAFF/APRIL system: life beyond B lymphocytes
    • Ng LG et al. The BAFF/APRIL system: life beyond B lymphocytes. Mol Immunol 2005; 42 (7): 763-772.
    • (2005) Mol Immunol , vol.42 , Issue.7 , pp. 763-772
    • Ng, L.G.1
  • 9
    • 27644461904 scopus 로고    scopus 로고
    • BLyS and APRIL in rheumatoid arthritis
    • Seyler TM et al. BLyS and APRIL in rheumatoid arthritis. J Clin Invest 2005; 115 (11): 3083-3092.
    • (2005) J Clin Invest , vol.115 , Issue.11 , pp. 3083-3092
    • Seyler, T.M.1
  • 10
    • 70350517490 scopus 로고    scopus 로고
    • Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rhe umatoid arthritis
    • Vallerskog T et al. Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rhe umatoid arthritis. Arthritis Res Ther 2006; 8 (6): 167.
    • (2006) Arthritis Res Ther , vol.8 , Issue.6 , pp. 167
    • Vallerskog, T.1
  • 11
    • 0036162436 scopus 로고    scopus 로고
    • The molecular architecture of the TNF superfamily
    • Bodmer JL et al. The molecular architecture of the TNF superfamily. Trends Biochem Sci 2002; 27: 19-26.
    • (2002) Trends Biochem Sci , vol.27 , pp. 19-26
    • Bodmer, J.L.1
  • 12
    • 0142218540 scopus 로고    scopus 로고
    • Actions of BAFF in B cell maturation and its effects on the development of autoimmune disease
    • Melchers F. Actions of BAFF in B cell maturation and its effects on the development of autoimmune disease. Ann Rheum Dis 2003; 62 (2): 25-27.
    • (2003) Ann Rheum Dis , vol.62 , Issue.2 , pp. 25-27
    • Melchers, F.1
  • 13
    • 0033371496 scopus 로고    scopus 로고
    • Characterization of a new member of the TNF family expressed on antigen presenting cells
    • Tribouley C et al. Characterization of a new member of the TNF family expressed on antigen presenting cells. Biol Chem 1999; 380: 1443-1447.
    • (1999) Biol Chem , vol.380 , pp. 1443-1447
    • Tribouley, C.1
  • 14
    • 0035175146 scopus 로고    scopus 로고
    • Synthesis and release of B-lymphocyte stimulator from myeloid cells
    • Nardelli B et al. Synthesis and release of B-lymphocyte stimulator from myeloid cells. Blood 2000; 97: 198-204.
    • (2000) Blood , vol.97 , pp. 198-204
    • Nardelli, B.1
  • 15
    • 0036732753 scopus 로고    scopus 로고
    • DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
    • Litinskiy MB et al. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat Immunol 2002; 3: 822-829.
    • (2002) Nat Immunol , vol.3 , pp. 822-829
    • Litinskiy, M.B.1
  • 16
    • 0037415599 scopus 로고    scopus 로고
    • G-CSF-stimulated neutrophils are a prominent sour ce of functional BLyS
    • Scapini P et al. G-CSF-stimulated neutrophils are a prominent sour ce of functional BLyS. J Exp Med 2003; 197: 297-302.
    • (2003) J Exp Med , vol.197 , pp. 297-302
    • Scapini, P.1
  • 17
    • 0141643347 scopus 로고    scopus 로고
    • DeltaBAFF, an alternate splice isoform that regula tes receptor binding and biopresentation of the B cell survival cytokine, BAFF
    • Gavin AL et al. DeltaBAFF, an alternate splice isoform that regula tes receptor binding and biopresentation of the B cell survival cytokine, BAFF. J Biol Chem 2003; 278: 38220-38228.
    • (2003) J Biol Chem , vol.278 , pp. 38220-38228
    • Gavin, A.L.1
  • 18
    • 21244506678 scopus 로고    scopus 로고
    • DeltaBAFF, a splice isoform of BAFF, opposes fulllength BAFF activity in vivo in transgenic mouse models
    • Gavin AL et al. DeltaBAFF, a splice isoform of BAFF, opposes fulllength BAFF activity in vivo in transgenic mouse models. J Immu nol 2005; 175:319-328.
    • (2005) J Immu nol , vol.175 , pp. 319-328
    • Gavin, A.L.1
  • 19
    • 0037108490 scopus 로고    scopus 로고
    • BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases
    • Roschke V et al. BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases. J Immunol 2002; 169: 4314-4321.
    • (2002) J Immunol , vol.169 , pp. 4314-4321
    • Roschke, V.1
  • 20
    • 18644380147 scopus 로고    scopus 로고
    • The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways
    • Dejardin E et al. The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity 2002; 17: 525-535.
    • (2002) Immunity , vol.17 , pp. 525-535
    • Dejardin, E.1
  • 21
    • 1842633887 scopus 로고    scopus 로고
    • Reduced competitiveness of autoantigen-engaged B ce lls due to increased dependence on BAFF
    • Lesley R et al. Reduced competitiveness of autoantigen-engaged B ce lls due to increased dependence on BAFF. Immunity 2004; 20: 441-453.
    • (2004) Immunity , vol.20 , pp. 441-453
    • Lesley, R.1
  • 22
    • 0033532634 scopus 로고    scopus 로고
    • BAFF, a novel ligand of the tumor necrosis factor (TNF) family, stimulates B cell growth
    • Schneider P et al. BAFF, a novel ligand of the tumor necrosis factor (TNF) family, stimulates B cell growth. J Exp Med 1999;189: 1747-1756.
    • (1999) J Exp Med , vol.189 , pp. 1747-1756
    • Schneider, P.1
  • 23
    • 0033538468 scopus 로고    scopus 로고
    • BlyS: member of the tumor necrosis factor family and B lymphocyte stimulator
    • Moore PA et al. BlyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 1999; 285: 260-263.
    • (1999) Science , vol.285 , pp. 260-263
    • Moore, P.A.1
  • 24
    • 1542269691 scopus 로고    scopus 로고
    • BAFF production by antigen-presenting cells provi des T cell costimulation
    • Huard B et al. BAFF production by antigen-presenting cells provi des T cell costimulation. Int Immunol 2004; 16: 467-475.
    • (2004) Int Immunol , vol.16 , pp. 467-475
    • Huard, B.1
  • 25
    • 14044259331 scopus 로고    scopus 로고
    • Enhanced apoptotic cell clearance capacity and b cell survival factor production by IL-10-activated macrophages: impli cations for burkitt's lymphoma
    • Ogden CA et al. Enhanced apoptotic cell clearance capacity and b cell survival factor production by IL-10-activated macrophages: impli cations for burkitt's lymphoma. J Immunol 2005; 174: 3015-3023.
    • (2005) J Immunol , vol.174 , pp. 3015-3023
    • Ogden, C.A.1
  • 26
    • 19944428744 scopus 로고    scopus 로고
    • Proinflammatory mediators elicit the secretion of the intracellular B-lymphocyte stimulator (BLyS) pool that is stored in activated neutrophils: implications for inflammatory diseases
    • Scapini P et al. Proinflammatory mediators elicit the secretion of the intracellular B-lymphocyte stimulator (BLyS) pool that is stored in activated neutrophils: implications for inflammatory diseases. Blood 2004; 105: 830-837.
    • (2004) Blood , vol.105 , pp. 830-837
    • Scapini, P.1
  • 27
    • 34447515625 scopus 로고    scopus 로고
    • Tumor necrosis factor a activates release of B lym phocyte stimulator by neutrophils infiltrating the rheumatoid joint
    • Assi LK et al. Tumor necrosis factor a activates release of B lym phocyte stimulator by neutrophils infiltrating the rheumatoid joint. Arthritis & rheumatism 2007; 56 (6): 1776-1786.
    • (2007) Arthritis & rheumatism , vol.56 , Issue.6 , pp. 1776-1786
    • Assi, L.K.1
  • 28
    • 3342921914 scopus 로고    scopus 로고
    • The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers
    • Mackay F, Tangye SG. The role of the BAFF/APRIL system in B cell homeostasis and lymphoid cancers. Curr Opin Pharmacol 2004; 4: 347-354.
    • (2004) Curr Opin Pharmacol , vol.4 , pp. 347-354
    • Mackay, F.1    Tangye, S.G.2
  • 29
    • 20244384231 scopus 로고    scopus 로고
    • BAFF is produced by astrocytes and upregu lated in multiple sclerosis lesions and primary central nervous system lymphoma
    • Krumbholz M et al. BAFF is produced by astrocytes and upregu lated in multiple sclerosis lesions and primary central nervous system lymphoma. J Exp Med 2005; 201: 195-200.
    • (2005) J Exp Med , vol.201 , pp. 195-200
    • Krumbholz, M.1
  • 30
    • 11844301640 scopus 로고    scopus 로고
    • Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in respon se to proinflammatory cytokines
    • Ohata J et al. Fibroblast-like synoviocytes of mesenchymal origin express functional B cell-activating factor of the TNF family in respon se to proinflammatory cytokines. J Immunol 2005; 174: 864-870.
    • (2005) J Immunol , vol.174 , pp. 864-870
    • Ohata, J.1
  • 31
    • 0141672920 scopus 로고    scopus 로고
    • Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells
    • Gorelik L et al. Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells. J Exp Med 2003; 198:937-945.
    • (2003) J Exp Med , vol.198 , pp. 937-945
    • Gorelik, L.1
  • 32
    • 0036498694 scopus 로고    scopus 로고
    • The role of BAFF in B cell maturation. Tcell activation and autoimmunity
    • Mackay F, Mackay CR. The role of BAFF in B cell maturation. Tcell activation and autoimmunity. Trends Immunol 2002; 23: 113-115.
    • (2002) Trends Immunol , vol.23 , pp. 113-115
    • Mackay, F.1    Mackay, C.R.2
  • 33
    • 34247574625 scopus 로고    scopus 로고
    • B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling
    • Mackay F et al. B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling. Curr Opin Immunol 2007; 19 (3): 327-336.
    • (2007) Curr Opin Immunol , vol.19 , Issue.3 , pp. 327-336
    • Mackay, F.1
  • 34
    • 70349776991 scopus 로고    scopus 로고
    • Mesenchymal stromal cells from bone mar row of rheumatoid arthritis patients provide survival signals to B cells in vitro
    • Krivošíková M et al. Mesenchymal stromal cells from bone mar row of rheumatoid arthritis patients provide survival signals to B cells in vitro. Ann Rheum Dis 2007; 66 (Suppl II): 292.
    • (2007) Ann Rheum Dis , vol.66 , Issue.SUPPL. II , pp. 292
    • Krivošiková, M.1
  • 35
    • 0035860466 scopus 로고    scopus 로고
    • BAFF-R, a novel TNF receptor that specifical ly interacts with BAFF
    • Thompson JS et al. BAFF-R, a novel TNF receptor that specifical ly interacts with BAFF. Science 2001; 293: 2108-2111.
    • (2001) Science , vol.293 , pp. 2108-2111
    • Thompson, J.S.1
  • 36
    • 0037644586 scopus 로고    scopus 로고
    • The TNF family members BAFF and APRIL: the growing complexity
    • Mackay F, Ambrose C. The TNF family members BAFF and APRIL: the growing complexity. Cytokine Growth Factor Rev 2003; 14: 311-324.
    • (2003) Cytokine Growth Factor Rev , vol.14 , pp. 311-324
    • Mackay, F.1    Ambrose, C.2
  • 37
    • 0037097665 scopus 로고    scopus 로고
    • Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators
    • Hsu BL et al. Cutting edge: BLyS enables survival of transitional and mature B cells through distinct mediators. J Immunol 2002; 168: 5993-5996.
    • (2002) J Immunol , vol.168 , pp. 5993-5996
    • Hsu, B.L.1
  • 38
    • 0942268734 scopus 로고    scopus 로고
    • Peripheral B cell maturation: the intersection of selection and homeostasis
    • Cancro MP. Peripheral B cell maturation: the intersection of selection and homeostasis. Immunol Rev 2004; 197: 89-101.
    • (2004) Immunol Rev , vol.197 , pp. 89-101
    • Cancro, M.P.1
  • 39
    • 85047690330 scopus 로고    scopus 로고
    • BAFF selectively enhances the survival of plasmablasts generated from human memory B cells
    • Avery DT et al. BAFF selectively enhances the survival of plasmablasts generated from human memory B cells. J Clin Invest 2003; 112: 286-297.
    • (2003) J Clin Invest , vol.112 , pp. 286-297
    • Avery, D.T.1
  • 40
    • 3142671331 scopus 로고    scopus 로고
    • B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells
    • Ng LG et al. B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol 2004; 173: 807-817.
    • (2004) J Immunol , vol.173 , pp. 807-817
    • Ng, L.G.1
  • 41
    • 9644266695 scopus 로고    scopus 로고
    • The BLyS family of ligands and receptors: an archety pe for nichespecific homeostatic regulation
    • Cancro MP. The BLyS family of ligands and receptors: an archety pe for nichespecific homeostatic regulation. Immunol Rev 2004; 202: 237-249.
    • (2004) Immunol Rev , vol.202 , pp. 237-249
    • Cancro, M.P.1
  • 42
    • 0039792391 scopus 로고    scopus 로고
    • NF-ATactivation induced by a CAMLinteracting member of the tumor necrosis factor receptor superfamily
    • Von Bulow GU, Bram RJ. NF-ATactivation induced by a CAMLinteracting member of the tumor necrosis factor receptor superfamily. Science 1997; 278: 138-141.
    • (1997) Science , vol.278 , pp. 138-141
    • Von Bulow, G.U.1    Bram, R.J.2
  • 43
    • 0036634390 scopus 로고    scopus 로고
    • BAFF: a fundamental survival factor for B cells
    • Mackay F, Browning JL. BAFF: a fundamental survival factor for B cells. Nat Rev Immunol 2002; 2: 465-475.
    • (2002) Nat Rev Immunol , vol.2 , pp. 465-475
    • Mackay, F.1    Browning, J.L.2
  • 44
    • 0038692705 scopus 로고    scopus 로고
    • BAFF AND APRIL: a tutorial on B cell survival
    • Mackay F et al. BAFF AND APRIL: a tutorial on B cell survival. Annu Rev Immunol 2003; 21: 231-264.
    • (2003) Annu Rev Immunol , vol.21 , pp. 231-264
    • Mackay, F.1
  • 45
    • 4644241216 scopus 로고    scopus 로고
    • CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10
    • He B et al. CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10. J Immunol 2004; 173: 4479-4491.
    • (2004) J Immunol , vol.173 , pp. 4479-4491
    • He, B.1
  • 46
    • 0034694088 scopus 로고    scopus 로고
    • BAFF mediates survival of peripheral immature B lymphocytes
    • Batten M et al. BAFF mediates survival of peripheral immature B lymphocytes. J Exp Med 2000;192: 1453-1465.
    • (2000) J Exp Med , vol.192 , pp. 1453-1465
    • Batten, M.1
  • 47
    • 0035576369 scopus 로고    scopus 로고
    • T cell costimulation by the TNF ligand BAFF
    • Huard B et al. T cell costimulation by the TNF ligand BAFF. J Immunol 2001; 167: 6225-6231.
    • (2001) J Immunol , vol.167 , pp. 6225-6231
    • Huard, B.1
  • 48
    • 17844381069 scopus 로고    scopus 로고
    • BAFF augments certain Thl-associated in flammatory responses
    • Sutherland APR et al. BAFF augments certain Thl-associated in flammatory responses. J Immunol 2005; 174: 5537-5544.
    • (2005) J Immunol , vol.174 , pp. 5537-5544
    • Sutherland, A.P.R.1
  • 49
    • 0034918211 scopus 로고    scopus 로고
    • TACI-ligand interactions are required for T cell activation and collagen induced arthritis in mice
    • Wang H et al. TACI-ligand interactions are required for T cell activation and collagen induced arthritis in mice. Nat Immunol 2001; 2: 632-637.
    • (2001) Nat Immunol , vol.2 , pp. 632-637
    • Wang, H.1
  • 50
    • 7244223338 scopus 로고    scopus 로고
    • BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses
    • Ye Q et al. BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses. Eur J Immunol 2004; 34: 27-50.
    • (2004) Eur J Immunol , vol.34 , pp. 27-50
    • Ye, Q.1
  • 51
    • 12944249540 scopus 로고    scopus 로고
    • Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenicmice
    • Khare SD et al. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenicmice. ProcNatl Acad Sci USA 2000; 97:3370-3375.
    • (2000) ProcNatl Acad Sci USA , vol.97 , pp. 3370-3375
    • Khare, S.D.1
  • 52
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • Mackay F et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 1999;190: 1697-1710.
    • (1999) J Exp Med , vol.190 , pp. 1697-1710
    • Mackay, F.1
  • 53
    • 0035797908 scopus 로고    scopus 로고
    • Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficien cy
    • Yan M et al. Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficien cy. Curr Biol 2001; 11: 1547-1552.
    • (2001) Curr Biol , vol.11 , pp. 1547-1552
    • Yan, M.1
  • 54
    • 17944375043 scopus 로고    scopus 로고
    • TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: impaired B cell maturation in mice lacking BLyS
    • Gross JA et al. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease: impaired B cell maturation in mice lacking BLyS. Immunity 2001; 15: 289-302.
    • (2001) Immunity , vol.15 , pp. 289-302
    • Gross, J.A.1
  • 55
    • 44849097480 scopus 로고    scopus 로고
    • Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL
    • Benson MJ et al. Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. J Immunol 2008; 180 (6): 3655-3659.
    • (2008) J Immunol , vol.180 , Issue.6 , pp. 3655-3659
    • Benson, M.J.1
  • 56
    • 0025758478 scopus 로고
    • Phenotypic and genetic characterization of a unique B lymphocyte deficiency in strain A/WySnJ mice
    • Miller DJ, Hayes CE. Phenotypic and genetic characterization of a unique B lymphocyte deficiency in strain A/WySnJ mice. Eur J Immu nol 1991; 21: 1123-1130.
    • (1991) Eur J Immu nol , vol.21 , pp. 1123-1130
    • Miller, D.J.1    Hayes, C.E.2
  • 57
    • 4043146475 scopus 로고    scopus 로고
    • B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation
    • Shulga-Morskaya S et al. B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation. J Immunol 2004; 173:2331-2341.
    • (2004) J Immunol , vol.173 , pp. 2331-2341
    • Shulga-Morskaya, S.1
  • 58
    • 0035004320 scopus 로고    scopus 로고
    • Regulation of the T-independent humoral res ponse by TACI
    • von Bulow GU et al. Regulation of the T-independent humoral res ponse by TACI. Immunity 2001; 14: 573-582.
    • (2001) Immunity , vol.14 , pp. 573-582
    • von Bulow, G.U.1
  • 59
    • 0034919939 scopus 로고    scopus 로고
    • Activation and accumulation of B cells in TACI-deficient mice
    • Yan M et al. Activation and accumulation of B cells in TACI-deficient mice. Nat Immunol 2001; 2: 638-643.
    • (2001) Nat Immunol , vol.2 , pp. 638-643
    • Yan, M.1
  • 60
    • 0037332043 scopus 로고    scopus 로고
    • Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor
    • Seshasayee D et al. Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor. Immunity 2003; 18: 279-288.
    • (2003) Immunity , vol.18 , pp. 279-288
    • Seshasayee, D.1
  • 61
    • 12344297875 scopus 로고    scopus 로고
    • TACI and BAFF-R mediate isotype switching in B cells
    • Castigli E et al. TACI and BAFF-R mediate isotype switching in B cells. J Exp Med 2005; 201: 35-39.
    • (2005) J Exp Med , vol.201 , pp. 35-39
    • Castigli, E.1
  • 62
    • 23044463627 scopus 로고    scopus 로고
    • TACI is mutant in common variable immunodefi ciency and IgA deficiency
    • Castigli E et al. TACI is mutant in common variable immunodefi ciency and IgA deficiency. Nat Genet 2005; 37: 829-834.
    • (2005) Nat Genet , vol.37 , pp. 829-834
    • Castigli, E.1
  • 63
    • 23044443492 scopus 로고    scopus 로고
    • Mutations in TNFRSF13B encoding TACI are asso ciated with common variable immunodeficiency in humans
    • Salzer U et al. Mutations in TNFRSF13B encoding TACI are asso ciated with common variable immunodeficiency in humans. Nat Genet 2005; 37: 820-828.
    • (2005) Nat Genet , vol.37 , pp. 820-828
    • Salzer, U.1
  • 64
    • 0035007222 scopus 로고    scopus 로고
    • B cell maturation protein, which binds the Tumor Necrosis Factor family members BAFF and APRIL, is dispensable for humoral immune responses
    • Xu S, Lam KP. B cell maturation protein, which binds the Tumor Necrosis Factor family members BAFF and APRIL, is dispensable for humoral immune responses. Mol Cell Biol 2001; 21: 4067-4074.
    • (2001) Mol Cell Biol , vol.21 , pp. 4067-4074
    • Xu, S.1    Lam, K.P.2
  • 65
    • 0347285357 scopus 로고    scopus 로고
    • BCMA is essential for the survival of long-lived bone marrow plasma cells
    • O'Connor BP et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med 2004; 199: 91-98.
    • (2004) J Exp Med , vol.199 , pp. 91-98
    • O'Connor, B.P.1
  • 66
    • 23844438230 scopus 로고    scopus 로고
    • B cell maturation antigen, the receptor for a proliferationinducing ligand and B cell-activating factor of the TNF family, in duces antigen presentation in B cells
    • Yang M et al. B cell maturation antigen, the receptor for a proliferationinducing ligand and B cell-activating factor of the TNF family, in duces antigen presentation in B cells. J Immunol 2005; 175: 2814-2824.
    • (2005) J Immunol , vol.175 , pp. 2814-2824
    • Yang, M.1
  • 67
    • 17344380531 scopus 로고    scopus 로고
    • TACI and BCMA are receptors for a TNF homologue implicated in B cell autoimmune disease
    • Gross JA et al. TACI and BCMA are receptors for a TNF homologue implicated in B cell autoimmune disease. Nature 2000; 404: 995-999.
    • (2000) Nature , vol.404 , pp. 995-999
    • Gross, J.A.1
  • 68
    • 23844518421 scopus 로고    scopus 로고
    • Expression and function of TNF family member B cell activating factor in the development of autoimmune arthritis
    • Zhang M et al. Expression and function of TNF family member B cell activating factor in the development of autoimmune arthritis. Int Immunol 2005; 17: 1081-1092.
    • (2005) Int Immunol , vol.17 , pp. 1081-1092
    • Zhang, M.1
  • 69
    • 27144545333 scopus 로고    scopus 로고
    • A role for B cell-activating factor of the TNF family in chemically induced autoimmunity
    • Zheng Y et al. A role for B cell-activating factor of the TNF family in chemically induced autoimmunity. J Immunol 2005; 175:6163-6168.
    • (2005) J Immunol , vol.175 , pp. 6163-6168
    • Zheng, Y.1
  • 70
    • 22244484101 scopus 로고    scopus 로고
    • BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus
    • Stohl W et al. BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus. Arthritis Rheum 2005; 52: 2080-2091.
    • (2005) Arthritis Rheum , vol.52 , pp. 2080-2091
    • Stohl, W.1
  • 71
    • 0035709440 scopus 로고    scopus 로고
    • Polymorphism and chromosomal mapping of the mouse gene for B cell activating factor belonging to the tumor necrosis factor family (Baff) and association with autoimmune phenotype
    • Jiang Y et al. Polymorphism and chromosomal mapping of the mouse gene for B cell activating factor belonging to the tumor necrosis factor family (Baff) and association with autoimmune phenotype. Immunogenetics 2001; 53: 810-813.
    • (2001) Immunogenetics , vol.53 , pp. 810-813
    • Jiang, Y.1
  • 72
    • 0012589457 scopus 로고    scopus 로고
    • Analysis on the association of human BLYS (BAFF, TNFSF13B) polymorphisms with systemic lupus erythematosus and rheumatoid arthritis
    • Kawasaki A et al. Analysis on the association of human BLYS (BAFF, TNFSF13B) polymorphisms with systemic lupus erythematosus and rheumatoid arthritis. Genes Immun 2002; 3: 424-429.
    • (2002) Genes Immun , vol.3 , pp. 424-429
    • Kawasaki, A.1
  • 73
    • 34247550864 scopus 로고    scopus 로고
    • No evidence for an association between the-871 T/C promoter polymorphism in the B cell-activating factor gene and primary Sjogren's syndrome
    • Gottenberg JE et al. No evidence for an association between the-871 T/C promoter polymorphism in the B cell-activating factor gene and primary Sjogren's syndrome. Arthritis Res Ther 2006; 8: 30.
    • (2006) Arthritis Res Ther , vol.8 , pp. 30
    • Gottenberg, J.E.1
  • 74
    • 27844456394 scopus 로고    scopus 로고
    • BAFF is elevated in serum of patients with Wegener's granulomatosis
    • Krumbholz M et al. BAFF is elevated in serum of patients with Wegener's granulomatosis. J Autoimmun 2005; 25: 298-302.
    • (2005) J Autoimmun , vol.25 , pp. 298-302
    • Krumbholz, M.1
  • 75
    • 9144234090 scopus 로고    scopus 로고
    • TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma
    • Batten M et al. TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma. J Immunol 2004; 172: 812-822.
    • (2004) J Immunol , vol.172 , pp. 812-822
    • Batten, M.1
  • 76
    • 0036144353 scopus 로고    scopus 로고
    • Association of BAFF/BLyS overexpression and alte red B cell differentiation with Sjogren's syndrome
    • Groom J et al. Association of BAFF/BLyS overexpression and alte red B cell differentiation with Sjogren's syndrome. J Clin Invest 2002; 109: 59-68.
    • (2002) J Clin Invest , vol.109 , pp. 59-68
    • Groom, J.1
  • 77
    • 0036046296 scopus 로고    scopus 로고
    • B lymphocyte stimulator protein-associated increase in circulating autoantibody levels may require CD4+ T cells: lessons from HIV-infected patients
    • Stohl W et al. B lymphocyte stimulator protein-associated increase in circulating autoantibody levels may require CD4+ T cells: lessons from HIV-infected patients. Clin Immunol 2002;104: 115-122.
    • (2002) Clin Immunol , vol.104 , pp. 115-122
    • Stohl, W.1
  • 78
    • 3042548183 scopus 로고    scopus 로고
    • Toll-like receptor 9-dependent and-independent dendritic cell activation by chromatin-immunoglobulin G complexes
    • Boule MW et al. Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes. J Exp Med 2004; 199: 1631-1640.
    • (2004) J Exp Med , vol.199 , pp. 1631-1640
    • Boule, M.W.1
  • 79
    • 0035093233 scopus 로고    scopus 로고
    • Sustained improvement in rheumato id arthritis following a protocol designed to deplete B lymphocytes
    • Edwards JC, Cambridge G. Sustained improvement in rheumato id arthritis following a protocol designed to deplete B lymphocytes. Rheumatology 2001; 40: 205-211.
    • (2001) Rheumatology , vol.40 , pp. 205-211
    • Edwards, J.C.1    Cambridge, G.2
  • 80
    • 0042173008 scopus 로고    scopus 로고
    • SLE-Rituximab in lupus
    • Eisenberg R. SLE-Rituximab in lupus. Arthritis Res Ther 2003; 5: 157-159.
    • (2003) Arthritis Res Ther , vol.5 , pp. 157-159
    • Eisenberg, R.1
  • 81
    • 1242330312 scopus 로고    scopus 로고
    • B cell depletion in autoimmune disease
    • Gorman C et al. B cell depletion in autoimmune disease. Arthritis Res Ther 2003; 5(4): 17-21.
    • (2003) Arthritis Res Ther , vol.5 , Issue.4 , pp. 17-21
    • Gorman, C.1
  • 82
    • 1242285497 scopus 로고    scopus 로고
    • Targeting B cells for the treatment of rheumatoid arthritis
    • Oligino TJ, Dalrymple SA. Targeting B cells for the treatment of rheumatoid arthritis. Arthritis Res Ther 2003; 5(4): 7-11.
    • (2003) Arthritis Res Ther , vol.5 , Issue.4 , pp. 7-11
    • Oligino, T.J.1    Dalrymple, S.A.2
  • 83
    • 2942537697 scopus 로고    scopus 로고
    • Efficacy of B cell-targeted therapy with rituximab in patients with rheumatoid arthritis
    • Edwards JC et al. Efficacy of B cell-targeted therapy with rituximab in patients with rheumatoid arthritis. N Engl J Med 2004; 350: 2572-2581.
    • (2004) N Engl J Med , vol.350 , pp. 2572-2581
    • Edwards, J.C.1
  • 84
    • 12344329605 scopus 로고    scopus 로고
    • The current status of targeting BAFF/BLys for autoimmune diseases
    • Ramanujam M, Davidson A. The current status of targeting BAFF/BLys for autoimmune diseases, Arthritis Res Ther 2004; 6: 197-202.
    • (2004) Arthritis Res Ther , vol.6 , pp. 197-202
    • Ramanujam, M.1    Davidson, A.2
  • 85
    • 2642527095 scopus 로고    scopus 로고
    • Control of spontaneous B lymphocyte autoimmunity with adenovirus encoded soluble TACI
    • Liu W et al. Control of spontaneous B lymphocyte autoimmunity with adenovirus encoded soluble TACI. Arthritis Rheum 2004; 50: 1884-1896.
    • (2004) Arthritis Rheum , vol.50 , pp. 1884-1896
    • Liu, W.1
  • 86
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells lacking serum antibo dy reveals an antibody-independent role for B cells in murine lupus
    • Chan OTM et al. A novel mouse with B cells lacking serum antibo dy reveals an antibody-independent role for B cells in murine lupus. J Exp Med 1999; 189: 1639-1647.
    • (1999) J Exp Med , vol.189 , pp. 1639-1647
    • Chan, O.T.M.1
  • 87
    • 0035525528 scopus 로고    scopus 로고
    • From T to B and back again: positive feedback in systemic autoimmune disease
    • Shlomchik MJ et al. From T to B and back again: positive feedback in systemic autoimmune disease. Nat Rev Immunol 2001; 1: 147-153.
    • (2001) Nat Rev Immunol , vol.1 , pp. 147-153
    • Shlomchik, M.J.1
  • 88
    • 0035879123 scopus 로고    scopus 로고
    • Lymphoid neogenesis in rheumatoid synovitis
    • Takemura S et al. Lymphoid neogenesis in rheumatoid synovitis. J Immunol 2001; 167: 1072-1080.
    • (2001) J Immunol , vol.167 , pp. 1072-1080
    • Takemura, S.1
  • 89
    • 0035888030 scopus 로고    scopus 로고
    • T cell activation in rheumatoid synovium is B cell dependent
    • Takemura S et al. T cell activation in rheumatoid synovium is B cell dependent. J Immunol 2001; 167: 4710-4718.
    • (2001) J Immunol , vol.167 , pp. 4710-4718
    • Takemura, S.1
  • 90
    • 0038240921 scopus 로고    scopus 로고
    • Ectopic germinal center formation in rheumatoid synovitis
    • Weyland CM, Goronzy JJ. Ectopic germinal center formation in rheumatoid synovitis. Ann NY Acad Sci 2003; 987: 140-149.
    • (2003) Ann NY Acad Sci , vol.987 , pp. 140-149
    • Weyland, C.M.1    Goronzy, J.J.2
  • 91
    • 27144474948 scopus 로고    scopus 로고
    • B cell depletion inhibits arthritis in a collagen induced arthritis (CIA) model, but does not adversely affect humoral responses in a respiratory syncytial virus (RSV) vaccination model
    • Dunussi-Joannopoulos K et al. B cell depletion inhibits arthritis in a collagen induced arthritis (CIA) model, but does not adversely affect humoral responses in a respiratory syncytial virus (RSV) vaccination model. Blood 2005; 106: 2235-2243.
    • (2005) Blood , vol.106 , pp. 2235-2243
    • Dunussi-Joannopoulos, K.1
  • 92
    • 14844347864 scopus 로고    scopus 로고
    • Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis
    • O'Neill SK et al. Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis. J Immunol 2005; 174: 3781-3788.
    • (2005) J Immunol , vol.174 , pp. 3781-3788
    • O'Neill, S.K.1


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