Fast mouse PK (Fast PK): A rapid screening method to increase pharmacokinetic throughput in pre-clinical drug discovery

European Journal of Pharmaceutical Sciences

Volumn 47, Issue 2, 2012, Pages 444-450

  Reddy, Jitendar ^a   Madishetti, Sreedhar ^a   Vachaspati, Prakash R ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Drug discovery; High throughput screening; Pharmacokinetics

Indexed keywords

RIFAMPICIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SAFETY; DRUG SCREENING; FAST PHARMACOKINETICS; INTERMETHOD COMPARISON; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PHARMACOKINETICS; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, INTRAVENOUS; ADMINISTRATION, ORAL; ANIMALS; DRUG EVALUATION, PRECLINICAL; MALE; MICE; MICE, INBRED BALB C; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; RIFAMPIN;

EID: 84864408544     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.07.001     Document Type: Article

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