Protein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cells

Journal of Biological Chemistry

Volumn 287, Issue 31, 2012, Pages 26168-26176

  Haines, Ricci J ^a   Corbin, Karen D ^b   Pendleton, Laura C ^a   Eichler, Duane C ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b University of North Carolina   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININOSUCCINATE LYASE; ARGININOSUCCINATE SYNTHASE; BOVINE AORTIC ENDOTHELIAL CELLS; CALCIUM IONOPHORE; CITRULLINE; ENDOTHELIAL NITRIC-OXIDE SYNTHASE (ENOS); IN-VITRO; KINASE INHIBITION; L-ARGININE; NITRIC-OXIDE SYNTHASE; PROTEIN KINASE C; RATE LIMITING; RATE-LIMITING STEPS; SUBSTRATE ARGININE; THAPSIGARGINS; VASCULAR ENDOTHELIAL CELLS;

AMINO ACIDS; CALCIUM; ENDOTHELIAL CELLS; NITRIC OXIDE; PHOSPHORYLATION; POSITIVE IONS; SUBSTRATES;

ENZYMES;

ARGININOSUCCINATE SYNTHASE; CALCIUM IONOPHORE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROTEIN KINASE C ALPHA; SERINE; THAPSIGARGIN;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME REGULATION; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM;

ACETOPHENONES; AMINO ACID SUBSTITUTION; ANIMALS; AORTA; ARGININOSUCCINATE SYNTHASE; BENZOPYRANS; BRADYKININ; CALCIUM; CALCIUM SIGNALING; CATTLE; CELLS, CULTURED; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; INDOLES; ISOENZYMES; MALEIMIDES; MUTAGENESIS, SITE-DIRECTED; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OKADAIC ACID; PHOSPHORYLATION; PROTEIN KINASE C-ALPHA; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA INTERFERENCE; SERINE;

BOVINAE;

EID: 84864395361     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.378794     Document Type: Article

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