Calcium signalling in the endothelium

Handbook of Experimental Pharmacology

Volumn 176, Issue PART1, 2006, Pages 145-187

  Tran, Q K ^a   Watanabe, H ^b  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Calcium; Calcium entry; Calmodulin; Endothelial cells; Nitric oxide

Indexed keywords

CALCIUM CHANNEL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; NITRIC OXIDE; PROTEIN KINASE;

ANIMAL; CALCIUM SIGNALING; CHANNEL GATING; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; HUMAN; METABOLISM; MITOCHONDRION; REVIEW; SECOND MESSENGER; ULTRASTRUCTURE; VASCULAR ENDOTHELIUM;

ANIMALS; CALCIUM CHANNELS; CALCIUM SIGNALING; ENDOPLASMIC RETICULUM; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; ION CHANNEL GATING; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PROTEIN KINASES; SECOND MESSENGER SYSTEMS;

EID: 39049188436     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/3-540-32967-6_5     Document Type: Article

References (203)

1. Aarhus R, Graeff RM, Dickey DM, Walseth TF, Lee HC (1995) ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium-mobilizing metabolite fromNADP. J Biol Chem 270:30327-30333
2. Adams DJ, Hill MA (2004) Potassium channels and membrane potential in the modulation of intracellular calcium in vascular endothelial cells. J Cardiovasc Electrophysiol 15:598-610
3. Alvarez J, Montero M, Garcia-Sancho J (1991) Cytochrome P-450 may link intracellular Ca2+ stores with plasma membrane Ca2+ influx. Biochem J 274:193-197
4. Ando J, Kamiya A (1993) Blood flow and vascular endothelial cell function. Front Med Biol Eng 5:245-264
5. Anger M, Samuel JL, Marotte F, Wuytack F, Rappaport L, Lompre AM (1993) The sarco- (endo)plasmic reticulum Ca(2+)-ATPase mRNA isoform, SERCA 3, is expressed in endothelial and epithelial cells in various organs. FEBS Lett 334:45-48
6. Aramburu J, Rao A, Klee CB (2000) Calcineurin: from structure to function. Curr Top Cell Regul 36:237-295
7. Babnigg G, Bowersox SR, Villereal ML (1997) The role of pp60c-src in the regulation of calcium entry via store-operated calcium channels. J Biol Chem 272:29434-29437
8. Bakowski D, Glitsch MD, Parekh AB (2001) An examination of the secretion-like coupling model for the activation of the Ca2+ release-activated Ca2+ current I(CRAC) in RBL-1 cells. J Physiol 532:55-71
9. BerridgeM(2004) Conformational coupling: a physiological calcium entrymechanism. Sci STKE 2004:pe33
10. Berridge MJ (1990) Calcium oscillations. J Biol Chem 265:9583-9586
11. Berridge MJ (1993) Inositol trisphosphate and calcium signalling. Nature 361:315-325
12. Berridge MJ (1995) Capacitative calcium entry. Biochem J 312:1-11
13. Berridge MJ, Irvine RF (1984) Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature 312:315-321
14. Bhagyalakshmi A, Berthiaume F, Reich KM, Frangos JA (1992) Fluid shear stress stimulates membrane phospholipid metabolism in cultured human endothelial cells. J Vasc Res 29:443-449
15. Bishara NB, Murphy TV, Hill MA (2002) Capacitative Ca(2+) entry in vascular endothelial cells ismediatedviapathways sensitive to2aminoethoxydiphenylborate andxestospongin C. Br J Pharmacol 135:119-128
16. Blatter LA, Wier WG (1994) Nitric oxide decreases [Ca2+]i in vascular smooth muscle by inhibition of the calcium current. Cell Calcium 15:122-131
17. BolotinaVM,Najibi S, Palacino JJ, Pagano PJ,CohenRA(1994)Nitric oxide directly activates calcium-dependent potassium channels in vascular smoothmuscle. Nature 368:850-853
18. Bossu JL, Feltz A, Rodeau JL, Tanzi F (1989) Voltage-dependent transient calcium currents in freshly dissociated capillary endothelial cells. FEBS Lett 255:377-380
19. Bossu JL, Elhamdani A, Feltz A (1992) Voltage-dependent calcium entry in confluent bovine capillary endothelial cells. FEBS Lett 299:239-242
20. Bourguignon LY, Iida N, Sobrin L, Bourguignon GJ (1994) Identification of an IP3 receptor in endothelial cells. J Cell Physiol 159:29-34
21. Boyer JL, Waldo GL, Harden TK (1992) Beta gamma-subunit activation of G-proteinregulated phospholipase C. J Biol Chem 267:25451-25456
22. Brading AF, Sneddon P (1980) Evidence for multiple sources of calcium for activation of the contractile mechanism of guinea-pig taenia coli on stimulation with carbachol. Br J Pharmacol 70:229-240
23. BrauneisU, Gatmaitan Z, AriasIM(1992) Serotonin stimulates a Ca2+ permeant nonspecific cation channel in hepatic endothelial cells. Biochem Biophys Res Commun 186:1560-1566
24. Bredt DS, Snyder SH (1990) Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc Natl Acad Sci U S A 87:682-685
25. Broad LM, Cannon TR, Taylor CW (1999) A non-capacitative pathway activated by arachidonic acid is themajorCa2+entry mechanismin rat A7r5smoothmuscle cells stimulated with low concentrations of vasopressin. J Physiol 517:121-134
26. Broad LM, Braun FJ, Lievremont JP, Bird GS, Kurosaki T, Putney Jr. J.W. (2001) Role of the phospholipase C-inositol 1,4,5-trisphosphate pathway in calcium release-activated calcium current and capacitative calcium entry. J Biol Chem 276:15945-15952
27. Brophy CM, Mills I, Rosales O, Isales C, Sumpio BE (1993) Phospholipase C: a putative mechanotransducer for endothelial cell response to acute hemodynamic changes. Biochem Biophys Res Commun 190:576-581
28. Camps M, Carozzi A, Schnabel P, Scheer A, Parker PJ, Gierschik P (1992) Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits. Nature 360:684-686
29. Casteels R, Droogmans G (1981) Exchange characteristics of the noradrenaline-sensitive calcium store in vascular smoothmuscle cells or rabbit ear artery. J Physiol 317:263-279
30. Castonguay A, Robitaille R (2002) Xestospongin C is a potent inhibitor of SERCA at a vertebrate synapse. Cell Calcium 32:39-47
31. Cho HJ, Xie QW, Calaycay J,Mumford RA, Swiderek KM, Lee TD, Nathan C (1992) Calmodulin is a subunit of nitric oxide synthase from macrophages. J Exp Med 176:599-604
32. Cioffi DL,Wu S, Stevens T (2003) On the endothelial cell I(SOC). Cell Calcium 33:323-336
33. Clapham DE, Runnels LW, Strubing C (2001) The TRP ion channel family. Nat Rev Neurosci 2:387-396
34. Clapper DL,Walseth TF, Dargie PJ, LeeHC (1987) Pyridine nucleotide metabolites stimulate calcium release from sea urchin egg microsomes desensitized to inositol trisphosphate. J Biol Chem 262:9561-9568
35. Cohen RA,Weisbrod RM, GerickeM, YaghoubiM, Bierl C, Bolotina VM (1999)Mechanism of nitric oxide-induced vasodilatation: refilling of intracellular stores by sarcoplasmic reticulum Ca2+ ATPase and inhibition of store-operated Ca2+ influx. Circ Res 84:210-219
36. Colden-Stanfield M, SchillingWP, Possani LD, Kunze DL (1990) Bradykinin-induced potassium current in cultured bovine aortic endothelial cells. J Membr Biol 116:227-238
37. Cosens DJ, Manning A (1969) Abnormal electroretinogram from a Drosophila mutant. Nature 224:285-287
38. Crutchley DJ, Ryan JW, Ryan US, Fisher GH (1983) Bradykinin-induced release of prostacyclin and thromboxanes from bovine pulmonary artery endothelial cells. Studies with lower homologs and calcium antagonists. Biochim Biophys Acta 751:99-107
39. Csordas G, Thomas AP, Hajnoczky G (1999) Quasi-synaptic calcium signal transmission between endoplasmic reticulum and mitochondria. EMBO J 18:96-108
40. Csutora P, Su Z, Kim HY, Bugrim A, Cunningham KW, Nuccitelli R, Keizer JE, Hanley MR, Blalock JE, Marchase RB (1999) Calcium influx factor is synthesized by yeast and mammalian cells depleted of organellar calcium stores. Proc Natl Acad Sci U S A 96:121-126
41. Davies PF (1995) Flow-mediated endothelial mechanotransduction. Physiol Rev 75:519-560
42. Dedkova EN, Blatter LA (2002) Nitric oxide inhibits capacitative Ca2+ entry and enhances endoplasmic reticulum Ca2+ uptake in bovine vascular endothelial cells. J Physiol 539:77-91
43. Diver JM, Sage SO, Rosado JA (2001) The inositol trisphosphate receptor antagonist 2- aminoethoxydiphenylborate (2-APB) blocks Ca2+ entry channels in human platelets: cautions for its use in studying Ca2+ influx. Cell Calcium 30:323-329
44. Dolor RJ, Hurwitz LM, Mirza Z, Strauss HC, Whorton AR (1992) Regulation of extracellular calcium entry in endothelial cells: role of intracellular calcium pool. Am J Physiol 262:C171-C181
45. FalckeM,Hudson JL, Camacho P, Lechleiter JD (1999) Impact of mitochondrial Ca2+ cycling on pattern formation and stability. Biophys J 77:37-44
46. Fill M, Copello JA (2002) Ryanodine receptor calcium release channels. Physiol Rev 82:893-922
47. Fiorio Pla A,Munaron L (2001) Calcium influx, arachidonic acid, and control of endothelial cell proliferation. Cell Calcium 30:235-244
48. Fleming I, Busse R (1997) Tyrosine phosphorylation and bradykinin-induced signaling in endothelial cells. Am J Cardiol 80:102A-109A
49. Fleming I, Fisslthaler B, Busse R (1995) Calcium signaling in endothelial cells involves activation of tyrosine kinases and leads to activation of mitogen-activated protein kinases. Circ Res 76:522-529
50. Freichel M, Schweig U, Stauffenberger S, Freise D, Schorb W, Flockerzi V (1999) Storeoperated cation channels in the heart and cells of the cardiovascular system. Cell Physiol Biochem 9:270-283
51. Freichel M, Suh SH, Pfeifer A, Schweig U, Trost C,Weissgerber P, Biel M, Philipp S, Freise D, Droogmans G, Hofmann F, Flockerzi V, Nilius B (2001) Lack of an endothelial storeoperated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4?/? mice. Nat Cell Biol 3:121-127
52. Furuichi T, Yoshikawa S, Miyawaki A, Wada K, Maeda N, Mikoshiba K (1989) Primary structure and functional expression of the inositol 1,4,5-trisphosphate- binding protein P400. Nature 342:32-38
53. Galione A, Lee HC, Busa WB (1991) Ca(2+)-induced Ca2+ release in sea urchin egg homogenates: modulation by cyclic ADP-ribose. Science 253:1143-1146
54. Garcia JG, Lazar V, Gilbert-McClain LI, Gallagher PJ, Verin AD (1997) Myosin light chain kinase in endothelium: molecular cloning and regulation. Am J Respir Cell Mol Biol 16:489-494
55. Genazzani AA, Galione A (1996) Nicotinic acid-adenine dinucleotide phosphate mobilizes Ca2+ from a thapsigargin-insensitive pool. Biochem J 315:721-725
56. Gericke M, Droogmans G, Nilius B (1993) Thapsigargin discharges intracellular calcium stores and induces transmembrane currents in human endothelial cells. Pflugers Arch 422:552-557
57. Goldbeter A, Dupont G, Berridge MJ (1990) Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation. Proc Natl Acad Sci U S A 87:1461-1465
58. Gregory RB, Rychkov G, Barritt GJ (2001) Evidence that 2-aminoethyl diphenylborate is a novel inhibitor of store-operated Ca2+ channels in liver cells, and acts through a mechanism which does not involve inositol trisphosphate receptors. Biochem J 354:285-290
59. Groner M, Malchow D (1996) Calmodulin-antagonists inhibit vesicular Ca2+ uptake in Dictyostelium. Cell Calcium 19:105-111
60. Groschner K,GraierWF,KukovetzWR(1994)Histamine inducesK+,Ca2+,andCl? currents in human vascular endothelial cells. Role of ionic currents in stimulation of nitric oxide biosynthesis. Circ Res 75:304-314
61. Gu C, Cooper DM (1999) Calmodulin-binding sites on adenylyl cyclase type VIII. J Biol Chem 274:8012-8021
62. Gunter TE, Pfeiffer DR (1990) Mechanisms by which mitochondria transport calcium. Am J Physiol 258:C755-C786
63. Hajnoczky G, Hager R, Thomas AP (1999)Mitochondria suppress local feedback activation of inositol 1,4,5-trisphosphate receptors by Ca2+. J Biol Chem 274:14157-14162
64. Hardie RC, Minke B (1992) The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors. Neuron 8:643-651
65. Hardie RC, Minke B (1993) Novel Ca2+ channels underlying transduction in Drosophila photoreceptors: implications for phosphoinositide-mediated Ca2+ mobilization. Trends Neurosci 16:371-376
66. Hashimoto Y, Watanabe T, Kinoshita M, Tsukamoto K, Togo M, Horie Y, Matsuda Y, Kurokawa K (1993) Ca2+ entry pathways activated by the tumor promoter thapsigargin in human platelets. Biochim Biophys Acta 1220:37-41
67. He H, Venema VJ, Gu X, Venema RC,Marrero MB, Caldwell RB (1999) Vascular endothelial growth factor signals endothelial cell production of nitric oxide and prostacyclin through flk-1/KDR activation of c-Src. J Biol Chem 274:25130-25135
68. Helmlinger G, Berk BC,NeremRM(1995) Calciumresponses of endothelial cell monolayers subjected to pulsatile and steady laminar flow differ. Am J Physiol 269:C367-C375
69. Himmel HM,Whorton AR, StraussHC (1993) Intracellular calcium, currents, and stimulusresponse coupling in endothelial cells. Hypertension 21:112-127
70. Hofer AM, Curci S, Machen TE, Schulz I (1996) ATP regulates calcium leak from agonistsensitive internal calcium stores. Faseb J 10:302-308
71. Holda JR, Blatter LA (1997) Capacitative calcium entry is inhibited in vascular endothelial cells by disruption of cytoskeletal microfilaments. FEBS Lett 403:191-196
72. Hosoki E, Iijima T (1994) Chloride-sensitive Ca2+ entry by histamine and ATP in human aortic endothelial cells. Eur J Pharmacol 266:213-218
73. Hoth M,PennerR(1992)Depletion of intracellular calciumstores activates a calciumcurrent in mast cells. Nature 355:353-356
74. Ichas F, Jouaville LS, Mazat JP (1997) Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals. Cell 89:1145-1153
75. Jacob R (1990) Agonist-stimulated divalent cation entry into single cultured human umbilical vein endothelial cells. J Physiol 421:55-77
76. Jacob R, Merritt JE, Hallam TJ, Rink TJ (1988) Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells. Nature 335:40-45
77. Jena M, Minore JF, O'Neill WC (1997) A volume-sensitive, IP3-insensitive Ca2+ store in vascular endothelial cells. Am J Physiol 273:C316-C322
78. Johns A, Lategan TW, Lodge NJ, Ryan US, Van Breemen C, Adams DJ (1987) Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells.Tissue Cell 19:733-745
79. Kanai AJ, Strauss HC, Truskey GA, Crews AL, Grunfeld S, Malinski T (1995) Shear stress induces ATP-independent transient nitric oxide release from vascular endothelial cells, measured directly with a porphyrinic microsensor. Circ Res 77:284-293
80. Khan SZ, Longland CL, Michelangeli F (2000) The effects of phenothiazines and other calmodulin antagonists on the sarcoplasmic and endoplasmic reticulum Ca(2+) pumps. Biochem Pharmacol 60:1797-1806
81. Kruse HJ, Grunberg B, SiessW,Weber PC (1994) Formation of biologically active autacoids is regulated by calcium influx in endothelial cells. Arterioscler Thromb 14:1821-1828
82. Kukkonen JP, Lund PE, Akerman KE (2001) 2-Aminoethoxydiphenyl borate reveals heterogeneity in receptor-activated Ca(2+) discharge and store-operated Ca(2+) influx. Cell Calcium 30:117-129
83. Kwan HY, Huang Y, Yao X (2000) Store-operated calcium entry in vascular endothelial cells is inhibited by cGMP via a protein kinase G-dependent mechanism. J Biol Chem 275:6758-6763
84. Kwan HY, Leung PC, Huang Y, Yao X (2003) Depletion of intracellular Ca2+ stores sensitizes the flow-induced Ca2+ influx in rat endothelial cells. Circ Res 92:286-292
85. Lambert TL,Kent RS,WhortonAR (1986) Bradykinin stimulation of inositol polyphosphate production in porcine aortic endothelial cells. J Biol Chem 261:15288-15293
86. Lee HC (2000) NAADP: an emerging calcium signaling molecule. J Membr Biol 173:1-8
87. Lee HC, Aarhus R (1993) Wide distribution of an enzyme that catalyzes the hydrolysis of cyclic ADP-ribose. Biochim Biophys Acta 1164:68-74
88. Lee HC, Aarhus R (1995) A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose. J Biol Chem 270:2152-2157
89. Lee HC, Walseth TF, Bratt GT, Hayes RN, Clapper DL (1989) Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activity. J Biol Chem 264:1608-1615
90. Lee HC, Aarhus R, Graeff RM (1995) Sensitization of calcium-induced calcium release by cyclic ADP-ribose and calmodulin. J Biol Chem 270:9060-9066
91. Lee KM, Villereal ML (1996) Tyrosine phosphorylation and activation of pp60c-src and pp125FAK in bradykinin-stimulated fibroblasts. Am J Physiol 270:C1430-C1437
92. Lee KM, Toscas K, Villereal ML (1993) Inhibition of bradykinin- and thapsigargin-induced Ca2+ entry by tyrosine kinase inhibitors. J Biol Chem 268:9945-9948
93. Lesh RE, Marks AR, Somlyo AV, Fleischer S, Somlyo AP (1993) Anti-ryanodine receptor antibody binding sites in vascular and endocardial endothelium. Circ Res 72:481-488
94. Levitan IB (1999) It is calmodulin after all! Mediator of the calcium modulation of multiple ion channels. Neuron 22:645-648
95. Liang W, Buluc M, van Breemen C, Wang X (2004) Vectorial Ca2+ release via ryanodine receptors contributes to Ca2+ extrusion from freshly isolated rabbit aortic endothelial cells. Cell Calcium 36:431-443
96. Liao JK, Homcy CJ (1993) The G proteins of the G alpha i and G alpha q family couple the bradykinin receptor to the release of endothelium-derived relaxing factor. J Clin Invest 92:2168-2172
97. Lin S, Fagan KA, Li KX, Shaul PW, Cooper DM, Rodman DM (2000) Sustained endothelial nitric-oxide synthase activationrequires capacitativeCa2+entry. JBiolChem275:17979-17985
98. Liu LH, Paul RJ, Sutliff RL, Miller ML, Lorenz JN, Pun RY, Duffy JJ, Doetschman T, Kimura Y, MacLennan DH, Hoying JB, Shull GE (1997) Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3. J Biol Chem 272:30538-30545
99. Lomax RB, Camello C, Van Coppenolle F, Petersen OH, Tepikin AV (2002) Basal and physiological Ca(2+) leak from the endoplasmic reticulum of pancreatic acinar cells. Second messenger-activated channels and translocons. J Biol Chem 277:26479-26485
100. Luckhoff A, Busse R (1990) Calcium influx into endothelial cells and formation of endothelium- derived relaxing factor is controlled by the membrane potential. Pflugers Arch 416:305-311
101. Luo D, Broad LM, Bird GS, Putney Jr. J.W. (2001) Mutual antagonism of calcium entry by capacitative and arachidonic acid-mediated calcium entry pathways. J Biol Chem 276:20186-20189
102. Ma HT, Patterson RL, van Rossum DB, Birnbaumer L, Mikoshiba K, Gill DL (2000) Requirement of the inositol trisphosphate receptor for activation of store-operated Ca2+ channels. Science 287:1647-1651
103. Ma HT, Venkatachalam K, Li HS, Montell C, Kurosaki T, Patterson RL, Gill DL (2001) Assessment of the role of the inositol 1,4,5-trisphosphate receptor in the activation of transient receptor potential channels and store-operated Ca2+ entry channels. J Biol Chem 276:18888-18896
104. Macer DR, Koch GL (1988) Identification of a set of calcium-binding proteins in reticuloplasm, the luminal content of the endoplasmic reticulum. J Cell Sci 91:61-70
105. Mak DO, McBride S, Foskett JK (1998) Inositol 1,4,5-trisphosphate activation of inositol trisphosphate receptor Ca2+ channel by ligand tuning of Ca2+ inhibition. Proc Natl Acad Sci U S A 95:15821-15825
106. Malli R, Frieden M, OsibowK, Zoratti C,MayerM, Demaurex N,GraierWF(2003) Sustained Ca2+ transfer across mitochondria is Essential for mitochondrial Ca2+ buffering, soreoperated Ca2+ entry, and Ca2+ store refilling. J Biol Chem 278:44769-44779
107. Malli R, Frieden M, Trenker M,GraierWF(2005) The role of mitochondria for Ca2+ refilling of the endoplasmic reticulum. J Biol Chem 280:12114-12122
108. Matsumoto H, BaronCB,Coburn RF (1995)Smoothmuscle stretch-activated phospholipase C activity. Am J Physiol 268:C458-C465
109. Meyer RD, Latz C, Rahimi N (2003) Recruitment and activation of phospholipase Cgamma1 by vascular endothelial growth factor receptor-2 are required for tubulogenesis and differentiation of endothelial cells. J Biol Chem 278:16347-16355
110. Meyer T, Stryer L (1988) Molecular model for receptor-stimulated calcium spiking. Proc Natl Acad Sci U S A 85:5051-5055
111. Meyer T, Holowka D, Stryer L (1988) Highly cooperative opening of calcium channels by inositol 1,4,5-trisphosphate. Science 240:653-656
112. Mignen O, Shuttleworth TJ (2000) I(ARC), a novel arachidonate-regulated, noncapacitative Ca(2+) entry channel. J Biol Chem 275:9114-9119
113. Mignery GA, Sudhof TC, Takei K, De Camilli P (1989) Putative receptor for inositol 1,4,5- trisphosphate similar to ryanodine receptor. Nature 342:192-195
114. MikoshibaK,Huchet M, Changeux JP (1979) Biochemical andimmunological studies on the P400 protein, a protein characteristic of the Purkinje cell frommouse and rat cerebellum. Dev Neurosci 2:254-275
115. Missiaen L, Callewaert G, De Smedt H, Parys JB (2001) 2-Aminoethoxydiphenyl borate affects the inositol 1,4,5-trisphosphate receptor, the intracellular Ca2+ pump and the non-specific Ca2+ leak from the non-mitochondrial Ca2+ stores in permeabilized A7r5 cells. Cell Calcium 29:111-116
116. Moncada S, Higgs A (1993) The L-arginine-nitric oxide pathway. N Engl J Med 329:2002-2012
117. Moneer Z, Taylor CW (2002) Reciprocal regulation of capacitative and non-capacitative Ca2+ entry inA7r5 vascular smoothmuscle cells: only the latter operates during receptor activation. Biochem J 362:13-21
118. Moneer Z, Dyer JL, Taylor CW (2003) Nitric oxide co-ordinates the activities of the capacitative and non-capacitative Ca2+-entry pathways regulated by vasopressin. Biochem J 370:439-448
119. Montell C, Birnbaumer L, Flockerzi V, Bindels RJ, Bruford EA, Caterina MJ, Clapham DE, Harteneck C, Heller S, Julius D, Kojima I, Mori Y, Penner R, PrawittD, Scharenberg AM, Schultz G, Shimizu N, Zhu MX (2002) A unified nomenclature for the superfamily of TRP cation channels. Mol Cell 9:229-231
120. Montero M, Alvarez J, Garcia-Sancho J (1991) Agonist-induced Ca2+ influx in human neutrophils is secondary to the emptying of intracellular calcium stores. Biochem J 277:73-79
121. Montero M, Alvarez J, Garcia-Sancho J (1992) Control of plasma-membrane Ca2+ entry by the intracellular Ca2+ stores. Kinetic evidence for a short-lived mediator. Biochem J 288:519-525
122. Montero M, Garcia-Sancho J, Alvarez J (1994) Phosphorylation down-regulates the storeoperated Ca2+ entry pathway of human neutrophils. J Biol Chem 269:3963-3967
123. MoosekerMS, Cheney RE (1995) Unconventionalmyosins. Annu Rev Cell Dev Biol 11:633-675
124. MoreauB, Straube S, Fisher RJ,Putney Jr. J.W.,ParekhAB(2005) Ca2+-calmodulin-dependent facilitation and Ca2+ inactivation of Ca2+ release-activated Ca2+ channels. J Biol Chem 280:8776-8783
125. Mountian I, Manolopoulos VG, De Smedt H, Parys JB, Missiaen L, Wuytack F (1999) Expression patterns of sarco/endoplasmic reticulum Ca(2+)-ATPase and inositol 1,4,5- trisphosphate receptor isoforms in vascular endothelial cells. Cell Calcium 25:371-380
126. NairnAC, PicciottoMR(1994) Calcium/calmodulin-dependent protein kinases. Semin Cancer Biol 5:295-303
127. Nilius B, Droogmans G, Wondergem R (2003) Transient receptor potential channels in endothelium: solving the calcium entry puzzle? Endothelium 10:5-15
128. Norwood N, Moore TM, Dean DA, Bhattacharjee R, Li M, Stevens T (2000) Store-operated calcium entry and increased endothelial cell permeability. Am J Physiol Lung Cell Mol Physiol 279:L815-L824
129. Oike M, Droogmans G, Nilius B (1994) Mechanosensitive Ca2+ transients in endothelial cells from human umbilical vein. Proc Natl Acad Sci U S A 91:2940-2944
130. Oka T, Sato K, Hori M, Ozaki H, Karaki H (2002) Xestospongin C, a novel blocker of IP3 receptor, attenuates the increase in cytosolic calcium level and degranulation that is induced by antigen in RBL-2H3 mast cells. Br J Pharmacol 135:1959-1966
131. Oldershaw KA, Taylor CW (1993) Luminal Ca2+ increases the affinity of inositol 1,4,5- trisphosphate for its receptor. Biochem J 292:631-633
132. Paltauf-Doburzynska J, Frieden M, Graier WF (1999) Mechanisms of Ca2+ store depletion in single endothelial cells in a Ca(2+)-free environment. Cell Calcium 25:345-353
133. Parekh AB, Penner R (1995) Depletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells. Proc Natl Acad Sci U S A 92:7907-7911
134. Parekh AB, Putney Jr. J.W. (2005) Store-operated calcium channels. Physiol Rev 85:757-810
135. Patterson RL, van Rossum DB, Gill DL (1999) Store-operated Ca2+ entry: evidence for a secretion-like coupling model. Cell 98:487-499
136. Persechini A, Stemmer PM (2002) Calmodulin is a limiting factor in the cell. Trends Cardiovasc Med 12:32-37
137. Petersen OH, Cancela JM (1999) New Ca2+-releasing messengers: are they important in the nervous system? Trends Neurosci 22:488-495
138. Picton C, Shenolikar S, Grand R, Cohen P (1983) Calmodulin as an integral subunit of phosphorylase kinase from rabbit skeletal muscle. Methods Enzymol 102:219-227
139. Popp R, Gogelein H (1992) A calcium and ATP sensitive nonselective cation channel in the antiluminal membrane of rat cerebral capillary endothelial cells. Biochim Biophys Acta 1108:59-66
140. Prasad AR, Logan SA, Nerem RM, Schwartz CJ, Sprague EA (1993) Flow-related responses of intracellular inositol phosphate levels in cultured aortic endothelial cells. Circ Res 72:827-836
141. Prince WT, Berridge MJ, Rasmussen H (1972) Role of calcium and adenosine-3′:5′-cyclic monophosphate in controlling fly salivary gland secretion. Proc Natl Acad Sci U S A 69:553-557
142. Putney Jr. J.W. (1986) A model for receptor-regulated calcium entry. Cell Calcium 7:1-12
143. Putney Jr. J.W. (1990) Capacitative calcium entry revisited. Cell Calcium 11:611-624
144. Raeymaekers L, Wuytack F, Eggermont J, De Schutter G, Casteels R (1983) Isolation of a plasma-membrane fraction from gastric smooth muscle. Comparison of the calcium uptake with that in endoplasmic reticulum. Biochem J 210:315-322
145. Rakhilin SV, Olson PA, Nishi A, Starkova NN, Fienberg AA, Nairn AC, Surmeier DJ, Greengard P (2004) A network of control mediated by regulator of calcium/calmodulindependent signaling. Science 306:698-701
146. Randriamampita C, Tsien RY (1993) Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx. Nature 364:809-814
147. Rosado JA, Jenner S, Sage SO (2000) A role for the actin cytoskeleton in the initiation and maintenance of store-mediated calcium entry in human platelets. Evidence for conformational coupling. J Biol Chem 275:7527-7533
148. Rzigalinski BA,Willoughby KA,Hoffman SW, Falck JR, Ellis EF (1999) Calciuminflux factor, further evidence it is 5, 6-epoxyeicosatrienoic acid. J Biol Chem 274:175-182
149. Sargeant P, Farndale RW, Sage SO (1993) ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets. J Biol Chem 268:18151-18156
150. Sedova M, Klishin A, Huser J, Blatter LA (2000) Capacitative Ca2+ entry is graded with degree of intracellular Ca2+ store depletion in bovine vascular endothelial cells. J Physiol 523:549-559
151. Shuttleworth TJ (1996) Arachidonic acid activates the noncapacitative entry of Ca2+ during [Ca2+]i oscillations. J Biol Chem 271:21720-21725
152. Shuttleworth TJ, Thompson JL (1996a) Ca2+ entry modulates oscillation frequency by triggering Ca2+ release. Biochem J 313:815-819
153. Shuttleworth TJ, Thompson JL (1996b) Evidence for a non-capacitative Ca2+ entry during [Ca2+] oscillations. Biochem J 316:819-824
154. Shuttleworth TJ, Thompson JL (1998) Muscarinic receptor activation of arachidonatemediated Ca2+ entry in HEK293 cells is independent of phospholipase C. J Biol Chem 273:32636-32643
155. Singh BB, Liu X, Tang J, Zhu MX, Ambudkar IS (2002) Calmodulin regulates Ca(2+)- dependent feedback inhibition of store-operated Ca(2+) influx by interaction with a site in the C terminus of TrpC1. Mol Cell 9:739-750
156. Solovyova N, Fernyhough P, Glazner G, Verkhratsky A (2002) Xestospongin C empties the ER calcium store but does not inhibit InsP3-induced Ca2+ release in cultured dorsal root ganglia neurones. Cell Calcium 32:49-52
157. Streb H, Irvine RF, Berridge MJ, Schulz I (1983) Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate. Nature 306:67-69
158. Takahashi R, Watanabe H, Zhang XX, Kakizawa H, Hayashi H, Ohno R (1997) Roles of inhibitors of myosin light chain kinase and tyrosine kinase on cation influx in agoniststimulated endothelial cells. Biochem Biophys Res Commun 235:657-662
159. Takeuchi K, Watanabe H, Tran QK, Ozeki M, Uehara A, Katoh H, Satoh H, Terada H, Ohashi K, Hayashi H (2003) Effects of cytochrome P450 inhibitors on agonist-induced Ca2+ responses and production of NO and PGI2 in vascular endothelial cells. Mol Cell Biochem 248:129-134
160. Takeuchi K, Watanabe H, Tran QK, Ozeki M, Sumi D, Hayashi T, Iguchi A, Ignarro LJ, Ohashi K, Hayashi H (2004) Nitric oxide: inhibitory effects on endothelial cell calcium signaling, prostaglandin I2 production and nitric oxide synthase expression. Cardiovasc Res 62:194-201
161. Taylor CW, Laude AJ (2002) IP3 receptors and their regulation by calmodulin and cytosolic Ca2+. Cell Calcium 32:321-334
162. Thastrup O, Cullen PJ, Drobak BK, Hanley MR, Dawson AP (1990) Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase. Proc Natl Acad Sci U S A 87:2466-2470
163. Tornquist K (1993)Modulatory effect of protein kinase C on thapsigargin-induced calcium entry in thyroid FRTL-5 cells. Biochem J 290:443-447
164. Tran QK,WatanabeH(2003)Myosin light chain kinase in endothelial cell calcium signaling andendothelial functions. In:PierceGN,NaganoM,ZahradkaP, DhallaNS(eds)Progress in experimental cardiology, vol 8. Kluwer Academic/Plenum Publishers, New York pp 163-174
165. Tran QK, Watanabe H, Zhang XX, Takahashi R, Ohno R (1999) Involvement of myosin light-chain kinase in chloride-sensitive Ca2+ influx in porcine aortic endothelial cells. Cardiovasc Res 44:623-631
166. Tran QK, Ohashi K,Watanabe H (2000) Calcium signalling in endothelial cells. Cardiovasc Res 48:13-22
167. Tran QK, Watanabe H, Le HY, Pan L, Seto M, Takeuchi K, Ohashi K (2001) Myosin light chain kinase regulates capacitative ca(2+) entry in human monocytes/macrophages. Arterioscler Thromb Vasc Biol 21:509-515
168. Tran QK, Black DJ, Persechini A (2003) Intracellular coupling via limiting calmodulin. J Biol Chem 278:24247-24250
169. Tran QK, BlackDJ, PersechiniA(2005) Dominant affectors in the calmodulin network shape the time courses of target responses in the cell. Cell Calcium 37:541-553
170. Trepakova ES, Cohen RA, BolotinaVM(1999)Nitric oxide inhibits capacitative cation influx in human platelets by promoting sarcoplasmic/ endoplasmic reticulum Ca2+-ATPasedependent refilling of Ca2+ stores. Circ Res 84:201-209
171. Trepakova ES, Csutora P,HuntonDL,Marchase RB, Cohen RA, BolotinaVM(2000) Calcium influx factor directly activates store-operated cation channels in vascular smoothmuscle cells. J Biol Chem 275:26158-26163
172. Vaca L, Kunze DL (1995) IP3-activated Ca2+ channels in the plasma membrane of cultured vascular endothelial cells. Am J Physiol 269:C733-C738
173. Vaca L, SinkinsWG, Hu Y, Kunze DL, Schilling WP (1994) Activation of recombinant trp by thapsigargin in Sf9 insect cells. Am J Physiol 267:C1501-C1505
174. Vazquez G, Lievremont JP, St J Bird G, Putney Jr. J.W. (2001) Human Trp3 forms both inositol trisphosphate receptor-dependent and receptor-independent store-operated cation channels in DT40 avian B lymphocytes. Proc Natl Acad Sci U S A 98:11777-11782
175. Vermassen E, Parys JB, Mauger JP (2004) Subcellular distribution of the inositol 1,4,5- trisphosphate receptors: functional relevance and molecular determinants. Biol Cell 96:3-17
176. Vincenzi FF, Larsen FL (1980) The plasmamembrane calciumpump: regulation by a soluble Ca2+ binding protein. Fed Proc 39:2427-2431
177. Vischer UM, Lang U, Wollheim CB (1998) Autocrine regulation of endothelial exocytosis: von Willebrand factor release is induced by prostacyclin in cultured endothelial cells. FEBS Lett 424:211-215
178. Walseth TF, Lee HC (1993) Synthesis and characterization of antagonists of cyclic-ADPribose- induced Ca2+ release. Biochim Biophys Acta 1178:235-242
179. Wang X, Lau F, Li L,YoshikawaA, vanBreemenC(1995)Acetylcholine-sensitive intracellular Ca2+ store in fresh endothelial cells and evidence for ryanodine receptors. Circ Res 77:37-42
180. Wang Y, Shin WS, Kawaguchi H, Inukai M, Kato M, Sakamoto A, Uehara Y, Miyamoto M, Shimamoto N, Korenaga R, Ando J, Toyo-oka T (1996) Contribution of sustained Ca2+ elevation for nitric oxide production in endothelial cells and subsequent modulation of Ca2+ transient in vascular smoothmuscle cells in coculture. J Biol Chem 271:5647-5655
181. Watanabe H, Takahashi R, Zhang XX, Kakizawa H, Hayashi H, Ohno R (1996) Inhibition of agonist-induced Ca2+ entry in endothelial cells by myosin light-chain kinase inhibitor. Biochem Biophys Res Commun 225:777-784
182. Watanabe H,TakahashiR,ZhangXX,GotoY,Hayashi H,AndoJ, IsshikiM, SetoM,HidakaH, Niki I, Ohno R (1998) An essential role of myosin light-chain kinase in the regulation of agonist- and fluid flow-stimulated Ca2+ influx in endothelial cells. FASEB J 12:341-348
183. Watanabe H, Takahashi R, Tran QK, Takeuchi K, Kosuge K, Satoh H, Uehara A, Terada H, Hayashi H, Ohno R, Ohashi K (1999) Increased cytosolic Ca(2+)
184. Watanabe H, Tran QK, Takeuchi K, Fukao M, Liu MY, Kanno M, Hayashi T, Iguchi A, Seto M, Ohashi K (2001) Myosin light-chain kinase regulates endothelial calcium entry and endothelium-dependent vasodilation. FASEB J 15:282-284
185. Wedel BJ,Vazquez G,McKayRR, St JBirdG, Putney Jr. J.W. (2003)Acalmodulin/inositol 1,4,5- trisphosphate (IP3) receptor-binding region targets TRPC3 to the plasma membrane in a calmodulin/IP3 receptor-independent process. J Biol Chem 278:25758-25765
186. Wibo M,MorelN,GodfraindT(1981) Differentiation ofCa2+pumps linked to plasmamembrane and endoplasmic reticulum in the microsomal fraction from intestinal smooth muscle. Biochim Biophys Acta 649:651-660
187. Wissing F, Nerou EP, TaylorCW(2002) A novel Ca2+-induced Ca2+ release mechanism mediated by neither inositol trisphosphate nor ryanodine receptors. Biochem J 361:605-611
188. Wood PG, Gillespie JI (1998a) Evidence for mitochondrial Ca(2+)-induced Ca2+ release in permeabilised endothelial cells. Biochem Biophys Res Commun 246:543-548
189. Wood PG, Gillespie JI (1998b) In permeabilised endothelial cells IP3-induced Ca2+ release is dependent on the cytoplasmic concentration of monovalent cations. Cardiovasc Res 37:263-270
190. Wu S, Sangerman J, Li M, Brough GH, Goodman SR, Stevens T (2001) Essential control of an endothelial cell ISOC by the spectrin membrane skeleton. J Cell Biol 154:1225-1233
191. Wuytack F, Raeymaekers L,Missiaen L (2002)Molecular physiology of the SERCAand SPCA pumps. Cell Calcium 32:279-305
192. Xie Q, Zhang Y, Zhai C, Bonanno JA (2002) Calcium influx factor from cytochrome P-450 metabolism and secretion-like coupling mechanisms for capacitative calcium entry in corneal endothelial cells. J Biol Chem 277:16559-16566
193. XuW, Liu L, Charles IG, Moncada S (2004) Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response. Nat Cell Biol 6:1129-1134
194. Yamada N, Makino Y, Clark RA, Pearson DW, Mattei MG, Guenet JL, Ohama E, Fujino I, Miyawaki A, Furuichi T, et al (1994)Human inositol 1,4,5-trisphosphate type-1 receptor, InsP3R1: structure, function, regulation of expression and chromosomal localization. Biochem J 302:781-790
195. Yamamoto K, Korenaga R, Kamiya A, Ando J (2000) Fluid shear stress activates Ca(2+) influx into human endothelial cells via P2X4 purinoceptors. Circ Res 87:385-391
196. Yamamoto N, Watanabe H, Kakizawa H, Hirano M, Kobayashi A, Ohno R (1995) A study on thapsigargin-induced calcium ion and cation influx pathways in vascular endothelial cells. Biochim Biophys Acta 1266:157-162
197. Yamamoto-Hino M, Sugiyama T, Hikichi K,Mattei MG, Hasegawa K, Sekine S, Sakurada K, MiyawakiA, FuruichiT,Hasegawa M, et al (1994)Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors. Receptors Channels 2:9-22
198. Yao X, Kwan HY, Chan FL, Chan NW, Huang Y (2000) A protein kinase G-sensitive channel mediates flow-induced Ca(2+) entry into vascular endothelial cells. Faseb J 14:932-938
199. Zeng W, Mak DO, Li Q, Shin DM, Foskett JK, Muallem S (2003) A new mode of Ca2+ signaling by G protein-coupled receptors: gating of IP3 receptor Ca2+ release channels by Gbetagamma. Curr Biol 13:872-876
200. Zhang H, Inazu M, Weir B, Buchanan M, Daniel E (1994a) Cyclopiazonic acid stimulates Ca2+ influx through non-specific cation channels in endothelial cells. Eur J Pharmacol 251:119-125
201. Zhang H, Inazu M, Weir B, Daniel E (1994b) Endothelin-1 inhibits inward rectifier potassium channels and activates nonspecific cation channels in cultured endothelial cells. Pharmacology 49:11-22
202. Zhao M, Li P, Li X, Zhang L, Winkfein RJ, Chen SR (1999) Molecular identification of the ryanodine receptor pore-forming segment. J Biol Chem 274:25971-25974
203. Ziegelstein RC, Spurgeon HA, Pili R, Passaniti A, Cheng L, Corda S, Lakatta EG, Capogrossi MC (1994) A functional ryanodine-sensitive intracellular Ca2+ store is present in vascular endothelial cells. Circ Res 74:151-156