Resistance to a novel antichlamydial compound is mediated through mutations in Chlamydia trachomatis secY

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 8, 2012, Pages 4296-4302

  Sandoz, Kelsi M ^a   Eriksen, Steven G ^a   Jeffrey, Brendan M ^a   Suchland, Robert J ^c   Putman, Timothy E ^a   Hruby, Dennis E ^b   Jordan, Robert ^b   Rockey, Daniel D ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b SIGA Technologies Incorporated   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(3 METHOXYPHENYL) (4,4,7 TRIMETHYL 4,5 DIHYDRO 1H [1,2]DITHIOLO[3,4C]QUINOLIN 1 YLIDENE)AMINE; ANTIINFECTIVE AGENT; CHLORAMPHENICOL; RIFAMPICIN; SECY PROTEIN; TETRACYCLINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIUM MUTANT; CHLAMYDIA; CHLAMYDIA CAVIAE; CHLAMYDIA TRACHOMATIS; CRYSTAL STRUCTURE; DRUG IDENTIFICATION; DRUG SPECIFICITY; GENE MUTATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SECY GENE; SEQUENCE ANALYSIS;

4-CHLORO-7-NITROBENZOFURAZAN; AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CELL LINE; CERAMIDES; CHLAMYDIA TRACHOMATIS; DRUG RESISTANCE, BACTERIAL; MICE; MICROBIAL SENSITIVITY TESTS; MUTATION; QUINOLINES;

EID: 84864386290     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00356-12     Document Type: Article

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