Mutual role of PGRN/TNF-α on osteopenia developing in obesity's inflammation state

Minerva Medica

Volumn 103, Issue 3, 2012, Pages 165-175

  Hossein Nezhad, A ^a   Mirzaei, K ^a,b   Ansar, H ^a   Khooshechin, G ^a   Ahmadivand, Z ^a   Keshavarz, S A ^b  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Bone diseases, metabolic; Cytokines; Interleukins; Tumor necrosis factor alpha

Indexed keywords

25 HYDROXYVITAMIN D; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; PROGRANULIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; BONE DENSITY; BONE METABOLISM; DIET RESTRICTION; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HUMAN; LUMBAR SPINE; MAJOR CLINICAL STUDY; MALE; OBESITY; OSTEOPENIA; SIGNAL TRANSDUCTION;

25-HYDROXYVITAMIN D 2; ADULT; BIOLOGICAL MARKERS; BODY COMPOSITION; BONE DENSITY; BONE DISEASES, METABOLIC; COLLAGEN; FEMALE; HIP; HUMANS; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKINS; IRAN; LUMBOSACRAL REGION; MALE; MIDDLE AGED; OBESITY; PARATHYROID HORMONE; PEPTIDE FRAGMENTS; PROTEIN PRECURSORS; RECEPTORS, TUMOR NECROSIS FACTOR; SPINE; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84864378256     PISSN: 00264806     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. Ferrante AJ. Obesity-induced inflammation: a metabolic dialogue in the language of inflammation. J Intern Med 2007;262:408-14.
2. Wellen K, Hotamisligil G. Obesity-induced inflammatory changes in adipose tissue. J Clin Invest 2003;112:1785-8. (Pubitemid 38063699)
3. Vikram N, Bhatt S, Bhushan B, Luthra K, Misra A, Poddar P et al. Associations of -308G/A polymorphism of tumor necrosis factor (TNF)-α gene and serum TNF-α levels with measures of obesity, intra-abdominal and subcutaneous abdominal fat, subclinical inflammation and insulin resistance in Asian Indians in north India. Dis Markers 2011;31:39-46.
4. Yen M, Tsai H, Wu Y, Hwa H, Lee B, Hsu P. TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation from monocyte/macrophage lineage precursor cells. Mol Immunol 2008;45:2205-13.
5. Roggia C, Gao Y, Cenci S, Weitzmann M, Toraldo G, Isaia G et al. Up-regulation of TNF-producing T cells in the bone marrow: a key mechanism by which estrogen deficiency induces bone loss in vivo. Proc Natl Acad Sci U S A 2001;98:13960-5. (Pubitemid 33116006)
6. Zhao L, Huang J, Zhang H, Wang Y, Matesic L, Takahata M et al. TNF Inhibits Mesenchymal Stem Cell Differentiation into Osteoblasts via the Ubiquitin E3 Ligase Wwp1. Stem Cells 2011 [Epub ahead of print].
7. Fulton J. New guidelines for the prevention and treatment of osteoporosis. National Osteoporosis Foundation. Med Health R I 1999;82:110-11.
8. Mirzaei K, Hossein-Nezhad A, Karimi M, Hosseinzadeh-Attar M, Jafari N, Najmafshar A et al. Effect of green tea extract on bone turnover markers in type 2 diabetic patients; A double-blind, placebo-controlled clinical trial study. DARU 2009;17:38-44.
9. Zhao L, Jiang H, Papasian C, Maulik D, Drees B, Hamilton J et al. Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis. J Bone Miner Res 2008;23:17-29.
10. Xiao W, He J, Zhang H, Hu W, Gu J, Yue H et al. ALOX12 polymorphisms are associated with fat mass but not peak bone mineral density in Chinese nuclear families. Int J Obes (Lond) 2011;35:378-86.
11. Felson D, Zhang Y, Hannan M, Anderson J. Effects of weight and body mass index on bone mineral density in men and women: the Framingham study. J Bone Miner Res 1993;8:567-73. (Pubitemid 23127916)
12. Weiler H, Janzen L, Green K, Grabowski J, Seshia M, Yuen K et al. Percentage body fat and bone mass in healthy Canadian females 10 to 19 years of age. Bone 2000;27:203-7. (Pubitemid 30458812)
13. Kobayashi N, Ueki K, Okazaki Y, Iwane A, Kubota N, Ohsugi M et al. Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance. Proc Natl Acad Sci U S A 2011;108:5753-8.
14. O'Rourke R, Kay T, Lyle E, Traxler S, Deveney C, Jobe B et al. Alterations in peripheral blood lymphocyte cytokine expression in obesity. Clin Exp Immunol 2006;146:39-46. (Pubitemid 44393836)
15. Cao J. Effects of obesity on bone metabolism. J Orthop Surg Res 2011;6:30.
16. Kessenbrock K, Fröhlich L, Sixt M, Lämmermann T, Pfister H, Bateman A et al. Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. J Clin Invest 2008;118:2438-47. (Pubitemid 351949772)
17. Naphade S, Kigerl K, Jakeman L, Kostyk S, Popovich P, Kuret J. Progranulin expression is upregulated after spinal contusion in mice. Acta Neuropathol 2010;119:123-33.
18. Martz L. New front against TNF. SciBX 2011; 4.
19. Bateman A, Bennett H. The granulin gene family: from cancer to dementia. Bioessays 2009;31:1245-54.
20. Liu C. Progranulin: A promising therapeutic target for rheumatoid arthritis. FEBS Lett 2011 [E-pub ahead of print].
21. Tang W, Lu Y, Tian Q, Zhang Y, Guo F, Liu G et al. The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice. Science 2011;332:478-84.
22. Bateman A, Bennett H. The granulin gene family: from cancer to dementia. Bioessays 2009;31:1245-54.
23. Gilbert L, He X, Farmer P, Boden S, Kozlowski M, Rubin J et al. Inhibition of osteoblast differentiation by tumor necrosis factor-alpha. Endocrinology 2000;141:3956-64.
24. Hossein-Nezhad A, Nikoo M, Mirzaei K, Mokhtarei F, Meybodi H. Comparison of the bone turn-over markers in patients with multiple sclerosis and healthy control subjects. European J Inflammation 2010;8:67-73.
25. Hotamisligil G, Shargill N, Spiegelman B. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science (New York, NY) 1993;259:87-91. (Pubitemid 23036092)
26. Van Dyke T, Serhan C. Resolution of inflammation: a new paradigm for the pathogenesis of periodontal diseases. J Dent Res 2003;82:82-90. (Pubitemid 41764116)
27. Anandacoomarasamy A, Caterson I, Sambrook P, Fransen M, March L. The impact of obesity on the musculoskeletal system. International journal of obesity (2005) 2008;32:211-22.
28. Halade G, Rahman M, Williams P, Fernandes G. High fat diet-induced animal model of age-associated obesity and osteoporosis. J Nutr Biochem 2010;21:1162-9.
29. Hotamisligil G, Arner P, Caro J, Atkinson R, Spiegelman B. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 1995;95:2409-15.
30. Mundy G. Osteoporosis and inflammation. Nutr Rev 2007;65:S147-51.
31. Vargas S, Naprta A, Glaccum M, Lee S, Kalinowski J, Lorenzo J. Interleukin-6 expression and histomorphometry of bones from mice deficient in receptors for interleukin-1 or tumor necrosis factor. J Bone Miner Res 1996;11:1736-44. (Pubitemid 26367684)
32. Ammann P, Rizzoli R, Bonjour J, Bourrin S, Meyer J, Vassalli P et al. Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency. J Clin Invest 1997;99:1699-703. (Pubitemid 27163821)
33. Kimble R, Matayoshi A, Vannice J, Kung V, Williams C, Pacifici R. Simultaneous block of interleukin-1 and tumor necrosis factor is required to completely prevent bone loss in the early postovariectomy period. Endocrinology 1995;136:3054-61.
34. Pfeilschifter J, Koditz R, Pfohl M, Schatz H. Changes in proinflammatory cytokine activity after menopause. Endocrine reviews 2002;23:90-119. (Pubitemid 34185307)
35. Jilka R. Cell biology of osteoclasts and osteoblast and the hormones and cytokines that control their development and activity. Report of the 1st Joint Meeting of the International Bone and Mineral Society and the European Calcified Tissue Society 2001.
36. Silva-Santos A, Matos M, Galvão-Castro B. Reabsorption in bone metabolism of HIV-positive patients. Acta Ortop Bras 2009;17.
37. Kong Y, Penninger J. Molecular control of bone remodeling and osteoporosis. Exp Gerontol 2000;35:947-56.
38. Lewis D, Liggitt H, Effmann E, Motley S, Teitelbaum S, Jepsen K et al. Osteoporosis induced in mice by overproduction of interleukin 4. Proc Natl Acad Sci U S A 1993;90:11618-22. (Pubitemid 24008690)
39. Kyung T, Lee J, Phan T, Yu R, Choi H. Osteoclastogenesis by bone marrow-derived macrophages is enhanced in obese mice. J Nutr 2009;139:502-6.
40. Aeschlimann D, Evans B. The vital osteoclast: how is it regulated? Cell Death Differ 2004;11:S5-7. (Pubitemid 39136790)
41. Yen M, Tsai H, Wu Y, Hwa H, Lee B, Hsu P. TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation from monocyte/macrophage lineage precursor cells. Mol Immunol 2008;45:2205-13.
42. Tsuboi M, Kawakami A, Nakashima T, Matsuoka N, Urayama S, Kawabe Y et al. Tumor necrosis factor-α and interleukin-1β increase the Fas-mediated apoptosis of human osteoblasts (see comments). J Lab Clin Med 1999;134:222-31. (Pubitemid 29423094)
43. Kobayashi K, Takahashi N, Jimi E, Udagawa N, Takami M, Kotake S et al. Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med 2000;191:275-86.
44. Yang C, Wang J, Hsieh S, Wang S, Hsu T, Lin W Decoy receptor 3 (DcR3) induces osteoclast formation from monocyte/macrophage lineage precursor cells. Cell Death Differ 2004;11:S97-107.
45. Cuevas-Antonio R, Cancino C, Arechavaleta-Velasco F, Andrade A, Barron L, Estrada I et al. Expression of progranulin (Acrogranin/PCDGF/Granulin-Epithelin Precursor) in benign and malignant ovarian tumors and activation of MAPK signaling in ovarian cancer cell line. Cancer Invest 2010;28:452-8.
46. Ong C, Bateman A. Progranulin (granulin-epithelin precursor, PC-cell derived growth factor, acrogranin) in proliferation and tumorigenesis. Histol Histopathol 2003;18:1275-88. (Pubitemid 37265028)
47. Daniel R, He Z, Carmichael K, Halper J, Bateman A. Cellular localization of gene expression for progranulin. J Histochem Cytochem 2000;48:999-1009. (Pubitemid 30421564)
48. Ong C, He Z, Kriazhev L, Shan X, Palfree R, Bateman A. Regulation of progranulin expression in myeloid cells. Acta Neuropathol 2010;119:123-33.
49. Chantry D, DeMaggio A, Brammer H, Raport C, Wood C, Schweickart V et al. Profile of human macrophage transcripts: insights into macrophage biology and identification of novel chemokines. J Leukoc Biol 1998;64:49-54. (Pubitemid 28304673)
50. Deng G, Zheng L, Chan F, Lenardo M. Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors. Nat Med 2005;11:1066-72. (Pubitemid 41486828)
51. Feldmann M, Maini R. Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases. Nat Med 2003;9:1245-50. (Pubitemid 37279838)
52. Zanin-Zhorov A, Ding Y, Kumari S, Attur M, Hippen K, Brown M et al. Protein kinase C-theta mediates negative feedback on regulatory T cell function. Science 2010;328:372-6.