Progranulin: A promising therapeutic target for rheumatoid arthritis

FEBS Letters

Volumn 585, Issue 23, 2011, Pages 3675-3680

  Liu, Chuan Ju ^a,b  

^a NYU HOSPITAL FOR JOINT DISEASES   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Atsttrin; Inflammatory arthritis; PGRN; TNF ; TNFR

Indexed keywords

ADALIMUMAB; ANTIINFLAMMATORY AGENT; ATSTTRIN; CARTILAGE OLIGOMERIC MATRIX PROTEIN; CELL SURFACE RECEPTOR; ETANERCEPT; INFLIXIMAB; METALLOPROTEINASE; PROGRANULIN; PROTEIN ADAMTS 12; PROTEIN ADAMTS 7; RECOMBINANT ATSTTRIN; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RECOMBINANT PROGRANULIN; RECOMBINANT PROTEIN; SCLEROPROTEIN; TOCILIZUMAB; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; TUMOR NECROSIS FACTOR ALPHA INHIBITOR; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; AUTOIMMUNE DISEASE; CANCER INHIBITION; CANCER RISK; CARTILAGE DEGENERATION; CHRONIC INFLAMMATION; DISEASE ACTIVITY; DISEASE CONTROL; DISEASE COURSE; DISEASE EXACERBATION; DISEASE SEVERITY; DRUG ABSORPTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG SAFETY; DRUG STABILITY; GENE; HUMAN; IMMUNOPATHOGENESIS; NONHUMAN; PGRN GENE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SINGLE DRUG DOSE;

ANIMALS; ARTHRITIS, RHEUMATOID; EXTRACELLULAR MATRIX PROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR TARGETED THERAPY; PROTEOLYSIS; RECOMBINANT FUSION PROTEINS;

EID: 80053268356     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.04.065     Document Type: Review

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