Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques

Human Gene Therapy

Volumn 23, Issue 7, 2012, Pages 754-768

  Verhoeyen, Els ^a   Relouzat, Francis ^b,c   Cambot, Marie ^d   Costa, Caroline ^a   Nègre, Didier ^a   Legrand, Faézeh ^e   Joubert, Christophe ^b   Grand, Roger Le ^b,c   Cosset, François Loïc ^a   Leboulch, Philippe ^b,c,f   Dubart Kupperschmitt, Anne ^d   Prost, Stephane ^b,c  

^a UNIVERSITÉ LYON 1   (France)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d INSERM   (France)

^e UNIVERSITY HOSPITAL OF BESANÇON   (France)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUDARABINE; FLUDARABINE PHOSPHATE; STEM CELL FACTOR; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CELL LINEAGE; CONTROLLED STUDY; HEMOPHILIA; MACACA; MALE; NONHUMAN; SIMIAN IMMUNODEFICIENCY VIRUS; WHOLE BODY RADIATION;

ANIMALS; ANTIGENS, CD34; CHIMERISM; GENETIC THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HEMOPHILIA A; HUMANS; LYMPHOCYTE COUNT; MACACA FASCICULARIS; MALE; MYELOABLATIVE AGONISTS; RADIATION-SENSITIZING AGENTS; RECOMBINANT PROTEINS; SIMIAN IMMUNODEFICIENCY VIRUS; STEM CELL FACTOR; TRANSDUCTION, GENETIC; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, AUTOLOGOUS; VIDARABINE; WHOLE-BODY IRRADIATION;

MACACA; PRIMATES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 84864365022     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2012.020     Document Type: Article

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