P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells

Journal of Neuro-Oncology

Volumn 107, Issue 3, 2012, Pages 503-516

  Bajbouj, K ^a,b   Mawrin, C ^a   Hartig, R ^a   Schulze Luehrmann, J ^c   Wilisch Neumann, A ^a   Roessner, A ^a   Schneider Stock, R ^a,c  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Cell cycle; Epigenetic regulation; Glioblastoma; p21WAF1; Trichostatin A

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1; HISTONE DEACETYLASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; HISTONE H4; MUTANT PROTEIN; PROTEIN P53; TRICHOSTATIN A; ANTINEOPLASTIC AGENT; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; HYDROXAMIC ACID; TP53 PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; DRUG TARGETING; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; EPIGENETICS; G1 PHASE CELL CYCLE CHECKPOINT; GLIOBLASTOMA; GLIOBLASTOMA CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MITOSIS; PROMOTER REGION; PROTEIN BINDING; PROTEIN TRANSPORT; S PHASE CELL CYCLE CHECKPOINT; TUMOR CELL; TUMOR RESISTANCE; UPREGULATION; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GENETICS; IMMUNOBLOTTING; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION PROFILING; GLIOBLASTOMA; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; IMMUNOBLOTTING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84864354431     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-011-0791-2     Document Type: Article

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