L-2-oxothiazolidine-4-carboxylic acid or α-lipoic acid Attenuates airway remodeling: Involvement of nuclear factor-κb (NF-κB), nuclear factor erythroid 2p45-related factor-2 (Nrf2), and hypoxia-inducible factor (HIF)

International Journal of Molecular Sciences

Volumn 13, Issue 7, 2012, Pages 7915-7937

  Park, Seoung Ju ^a   Lee, Kyung Sun ^a   Lee, Su Jeong ^a   Kim, So Ri ^a   Park, Seung Yong ^a   Jeon, Myoung Shin ^a   Lee, Heung Bum ^a   Lee, Yong Chul ^a  

^a Chonbuk National University Medical School   (South Korea)

Author keywords

Airway remodeling; Antioxidant; Hypoxia inducible factor; Nuclear factor erythroid 2p45 related factor 2; Nuclear factor B; Oxidative stress

Indexed keywords

2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; GLUTATHIONE; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OVALBUMIN; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; THIOCTIC ACID; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN; 2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID; ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIF1A PROTEIN, MOUSE; NFE2L2 PROTEIN, MOUSE; PYROGLUTAMIC ACID; THIAZOLIDINE DERIVATIVE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A;

AIRWAY REMODELING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS MUSCLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; LONG TERM EXPOSURE; LUNG FIBROSIS; MOUSE; MUCUS SECRETION; NONHUMAN; PROTEIN EXPRESSION; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; ANIMAL; ASTHMA; C57BL MOUSE; DRUG EFFECTS; DRUG SCREENING; IMMUNOLOGY; LUNG; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; SIGNAL TRANSDUCTION; SMOOTH MUSCLE;

ANIMALIA; MURINAE;

AIRWAY REMODELING; ANIMALS; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS; ASTHMA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DRUG EVALUATION, PRECLINICAL; FEMALE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LUNG; MAP KINASE SIGNALING SYSTEM; MICE, INBRED C57BL; MUSCLE, SMOOTH; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; PYRROLIDONECARBOXYLIC ACID; THIAZOLIDINES; THIOCTIC ACID; TRANSFORMING GROWTH FACTOR BETA1; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84864332617     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13077915     Document Type: Article

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