메뉴 건너뛰기




Volumn 13, Issue 8, 2012, Pages

Markers for individualised therapy in endometrial carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ARZOXIFENE; BETA CATENIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; ENDOXIFEN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR ALPHA; EVEROLIMUS; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FLUORODEOXYGLUCOSE F 18; FULVESTRANT; GROWTH DIFFERENTIATION FACTOR 15; LAPATINIB; LETROZOLE; MAMMALIAN TARGET OF RAPAMYCIN; MEDROXYPROGESTERONE; MEGESTROL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGESTERONE RECEPTOR; PROTEIN KINASE B; PROTEIN P16; PROTEIN P53; RIDAFOROLIMUS; STATHMIN; TEMSIROLIMUS; TRASTUZUMAB; TUMOR MARKER; UNINDEXED DRUG; VASCULOTROPIN;

EID: 84864330983     PISSN: 14702045     EISSN: 14745488     Source Type: Journal    
DOI: 10.1016/S1470-2045(12)70213-9     Document Type: Review
Times cited : (229)

References (75)
  • 3
    • 0029799612 scopus 로고    scopus 로고
    • Endometrial carcinoma
    • Rose PG Endometrial carcinoma. N Engl J Med 1996, 335:640-649.
    • (1996) N Engl J Med , vol.335 , pp. 640-649
    • Rose, P.G.1
  • 4
    • 77649130174 scopus 로고    scopus 로고
    • Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial
    • the PORTEC Study Group
    • Nout RA, Smit VT, Putter H, et al. Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): an open-label, non-inferiority, randomised trial. Lancet 2010, 375:816-823. the PORTEC Study Group.
    • (2010) Lancet , vol.375 , pp. 816-823
    • Nout, R.A.1    Smit, V.T.2    Putter, H.3
  • 5
    • 58149186453 scopus 로고    scopus 로고
    • Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): pooled trial results, systematic review, and meta-analysis
    • the ASTEC/EN.5 Study Group
    • Blake P, Swart AM, Orton J, et al. Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): pooled trial results, systematic review, and meta-analysis. Lancet 2009, 373:137-146. the ASTEC/EN.5 Study Group.
    • (2009) Lancet , vol.373 , pp. 137-146
    • Blake, P.1    Swart, A.M.2    Orton, J.3
  • 7
    • 80052010923 scopus 로고    scopus 로고
    • Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group
    • Oza AM, Elit L, Tsao MS, et al. Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group. J Clin Oncol 2011, 29:3278-3285.
    • (2011) J Clin Oncol , vol.29 , pp. 3278-3285
    • Oza, A.M.1    Elit, L.2    Tsao, M.S.3
  • 9
    • 63849308483 scopus 로고    scopus 로고
    • Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation
    • Salvesen HB, Carter SL, Mannelqvist M, et al. Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation. Proc Natl Acad Sci USA 2009, 106:4834-4839.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 4834-4839
    • Salvesen, H.B.1    Carter, S.L.2    Mannelqvist, M.3
  • 10
    • 70449370331 scopus 로고    scopus 로고
    • A perspective on challenges and issues in biomarker development and drug and biomarker codevelopment
    • Taube SE, Clark GM, Dancey JE, McShane LM, Sigman CC, Gutman SI A perspective on challenges and issues in biomarker development and drug and biomarker codevelopment. J Natl Cancer Inst 2009, 101:1453-1463.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1453-1463
    • Taube, S.E.1    Clark, G.M.2    Dancey, J.E.3    McShane, L.M.4    Sigman, C.C.5    Gutman, S.I.6
  • 11
    • 0020660717 scopus 로고
    • Two pathogenetic types of endometrial carcinoma
    • Bokhman JV Two pathogenetic types of endometrial carcinoma. Gynecol Oncol 1983, 15:10-17.
    • (1983) Gynecol Oncol , vol.15 , pp. 10-17
    • Bokhman, J.V.1
  • 12
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group
    • Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 2001, 69:89-95. Biomarkers Definitions Working Group.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 89-95
  • 13
    • 0026060964 scopus 로고
    • Relationship between surgical-pathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium: a Gynecologic Oncology Group study
    • Morrow CP, Bundy BN, Kurman RJ, et al. Relationship between surgical-pathological risk factors and outcome in clinical stage I and II carcinoma of the endometrium: a Gynecologic Oncology Group study. Gynecol Oncol 1991, 40:55-65.
    • (1991) Gynecol Oncol , vol.40 , pp. 55-65
    • Morrow, C.P.1    Bundy, B.N.2    Kurman, R.J.3
  • 14
    • 2142640269 scopus 로고    scopus 로고
    • Outcome of high-risk stage IC, grade 3, compared with stage I endometrial carcinoma patients: the Postoperative Radiation Therapy in Endometrial Carcinoma Trial
    • the postoperative Radiation Therapy in Endometrial Carcinoma Trial
    • Creutzberg CL, van Putten WL, Wárlám-Rodenhuis CC, et al. Outcome of high-risk stage IC, grade 3, compared with stage I endometrial carcinoma patients: the Postoperative Radiation Therapy in Endometrial Carcinoma Trial. J Clin Oncol 2004, 22:1234-1241. the postoperative Radiation Therapy in Endometrial Carcinoma Trial.
    • (2004) J Clin Oncol , vol.22 , pp. 1234-1241
    • Creutzberg, C.L.1    van Putten, W.L.2    Wárlám-Rodenhuis, C.C.3
  • 15
    • 67651085571 scopus 로고    scopus 로고
    • Clinical factors affecting the diagnostic accuracy of assessing dilation and curettage vs frozen section specimens for histologic grade and depth of myometrial invasion in endometrial carcinoma
    • 194.10
    • Wang X, Zhang H, Di W, Li W Clinical factors affecting the diagnostic accuracy of assessing dilation and curettage vs frozen section specimens for histologic grade and depth of myometrial invasion in endometrial carcinoma. Am J Obstet Gynecol 2009, 201:194.e1. 194.10.
    • (2009) Am J Obstet Gynecol , vol.201
    • Wang, X.1    Zhang, H.2    Di, W.3    Li, W.4
  • 16
    • 0037393654 scopus 로고    scopus 로고
    • Concordance of FIGO grade of endometrial adenocarcinomas in biopsy and hysterectomy specimens
    • Mitchard J, Hirschowitz L Concordance of FIGO grade of endometrial adenocarcinomas in biopsy and hysterectomy specimens. Histopathology 2003, 42:372-378.
    • (2003) Histopathology , vol.42 , pp. 372-378
    • Mitchard, J.1    Hirschowitz, L.2
  • 17
    • 34249868742 scopus 로고    scopus 로고
    • MRI of malignant neoplasms of the uterine corpus and cervix
    • Sala E, Wakely S, Senior E, Lomas D MRI of malignant neoplasms of the uterine corpus and cervix. AJR Am J Roentgenol 2007, 188:1577-1587.
    • (2007) AJR Am J Roentgenol , vol.188 , pp. 1577-1587
    • Sala, E.1    Wakely, S.2    Senior, E.3    Lomas, D.4
  • 18
    • 67349227876 scopus 로고    scopus 로고
    • Staging of endometrial cancer with MRI: guidelines of the European Society of Urogenital Imaging
    • the European Society of Urogenital Imaging
    • Kinkel K, Forstner R, Danza FM, et al. Staging of endometrial cancer with MRI: guidelines of the European Society of Urogenital Imaging. Eur Radiol 2009, 19:1565-1574. the European Society of Urogenital Imaging.
    • (2009) Eur Radiol , vol.19 , pp. 1565-1574
    • Kinkel, K.1    Forstner, R.2    Danza, F.M.3
  • 19
    • 61449442444 scopus 로고    scopus 로고
    • PET and PET-CT imaging of gynecological malignancies: present role and future promise
    • Basu S, Li G, Alavi A PET and PET-CT imaging of gynecological malignancies: present role and future promise. Expert Rev Anticancer Ther 2009, 9:75-96.
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 75-96
    • Basu, S.1    Li, G.2    Alavi, A.3
  • 20
    • 84655161371 scopus 로고    scopus 로고
    • Staging of endometrial carcinomas with MRI using traditional and novel MRI techniques
    • Haldorsen IS, Salvesen HB Staging of endometrial carcinomas with MRI using traditional and novel MRI techniques. Clin Radiol 2012, 67:2-12.
    • (2012) Clin Radiol , vol.67 , pp. 2-12
    • Haldorsen, I.S.1    Salvesen, H.B.2
  • 21
    • 51949102428 scopus 로고    scopus 로고
    • Preoperative local staging of endometrial cancer: transvaginal sonography vs. magnetic resonance imaging
    • Savelli L, Ceccarini M, Ludovisi M, et al. Preoperative local staging of endometrial cancer: transvaginal sonography vs. magnetic resonance imaging. Ultrasound Obstet Gynecol 2008, 31:560-566.
    • (2008) Ultrasound Obstet Gynecol , vol.31 , pp. 560-566
    • Savelli, L.1    Ceccarini, M.2    Ludovisi, M.3
  • 22
    • 84864710942 scopus 로고    scopus 로고
    • Standard 1.5-T MRI of endometrial carcinomas: modest agreement between radiologists
    • published online March 28.
    • Haldorsen IS, Husby JA, Werner HM, et al. Standard 1.5-T MRI of endometrial carcinomas: modest agreement between radiologists. Eur Radiol 2012, published online March 28. 10.1007/s00330-012-2400-y.
    • (2012) Eur Radiol
    • Haldorsen, I.S.1    Husby, J.A.2    Werner, H.M.3
  • 23
    • 79951578968 scopus 로고    scopus 로고
    • Three-dimensional ultrasound for assessing women with gynecological cancer: a systematic review
    • Alcázar JL, Jurado M Three-dimensional ultrasound for assessing women with gynecological cancer: a systematic review. Gynecol Oncol 2011, 120:340-346.
    • (2011) Gynecol Oncol , vol.120 , pp. 340-346
    • Alcázar, J.L.1    Jurado, M.2
  • 24
    • 46849091934 scopus 로고    scopus 로고
    • Detection of lymph node metastasis in cervical and uterine cancers by diffusion-weighted magnetic resonance imaging at 3T
    • Lin G, Ho KC, Wang JJ, et al. Detection of lymph node metastasis in cervical and uterine cancers by diffusion-weighted magnetic resonance imaging at 3T. J Magn Reson Imaging 2008, 28:128-135.
    • (2008) J Magn Reson Imaging , vol.28 , pp. 128-135
    • Lin, G.1    Ho, K.C.2    Wang, J.J.3
  • 25
    • 65549114650 scopus 로고    scopus 로고
    • Magnetic resonance lymphography: a novel technique for lymph node assessment in gynecologic malignancies
    • Narayanan P, Iyngkaran T, Sohaib SA, Reznek RH, Rockall AG Magnetic resonance lymphography: a novel technique for lymph node assessment in gynecologic malignancies. Cancer Biomark 2009, 5:81-88.
    • (2009) Cancer Biomark , vol.5 , pp. 81-88
    • Narayanan, P.1    Iyngkaran, T.2    Sohaib, S.A.3    Reznek, R.H.4    Rockall, A.G.5
  • 26
    • 78049348519 scopus 로고    scopus 로고
    • Comparative performance of the 2009 international Federation of gynecology and obstetrics' staging system for uterine corpus cancer
    • Lewin SN, Herzog TJ, Barrena Medel NI, et al. Comparative performance of the 2009 international Federation of gynecology and obstetrics' staging system for uterine corpus cancer. Obstet Gynecol 2010, 116:1141-1149.
    • (2010) Obstet Gynecol , vol.116 , pp. 1141-1149
    • Lewin, S.N.1    Herzog, T.J.2    Barrena Medel, N.I.3
  • 27
    • 84858335801 scopus 로고    scopus 로고
    • Revision of FIGO surgical staging in 2009 for endometrial cancer validates to improve risk stratification
    • the MoMaTEC study group
    • Werner HM, Trovik J, Marcickiewicz J, et al. Revision of FIGO surgical staging in 2009 for endometrial cancer validates to improve risk stratification. Gynecol Oncol 2012, 125:103-108. the MoMaTEC study group.
    • (2012) Gynecol Oncol , vol.125 , pp. 103-108
    • Werner, H.M.1    Trovik, J.2    Marcickiewicz, J.3
  • 28
    • 0023232969 scopus 로고
    • Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study
    • Creasman WT, Morrow CP, Bundy BN, Homesley HD, Graham JE, Heller PB Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group Study. Cancer 1987, 60(suppl):2035-2041.
    • (1987) Cancer , vol.60 , Issue.SUPPL. , pp. 2035-2041
    • Creasman, W.T.1    Morrow, C.P.2    Bundy, B.N.3    Homesley, H.D.4    Graham, J.E.5    Heller, P.B.6
  • 29
    • 57349198710 scopus 로고    scopus 로고
    • Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial
    • Benedetti Panici P, Basile S, Maneschi F, et al. Systematic pelvic lymphadenectomy vs. no lymphadenectomy in early-stage endometrial carcinoma: randomized clinical trial. J Natl Cancer Inst 2008, 100:1707-1716.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1707-1716
    • Benedetti Panici, P.1    Basile, S.2    Maneschi, F.3
  • 30
    • 77950188128 scopus 로고    scopus 로고
    • Survival effect of para-aortic lymphadenectomy in endometrial cancer (SEPAL study): a retrospective cohort analysis
    • Todo Y, Kato H, Kaneuchi M, Watari H, Takeda M, Sakuragi N Survival effect of para-aortic lymphadenectomy in endometrial cancer (SEPAL study): a retrospective cohort analysis. Lancet 2010, 375:1165-1172.
    • (2010) Lancet , vol.375 , pp. 1165-1172
    • Todo, Y.1    Kato, H.2    Kaneuchi, M.3    Watari, H.4    Takeda, M.5    Sakuragi, N.6
  • 31
    • 78650649478 scopus 로고    scopus 로고
    • The current status of lymphadenectomy in the management of endometrial cancer
    • Creasman WT The current status of lymphadenectomy in the management of endometrial cancer. Womens Health (Lond Engl) 2011, 7:33-35.
    • (2011) Womens Health (Lond Engl) , vol.7 , pp. 33-35
    • Creasman, W.T.1
  • 32
    • 58149191223 scopus 로고    scopus 로고
    • Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study
    • the ASTEC study group
    • Kitchener H, Swart AM, Qian Q, Amos C, Parmar MK Efficacy of systematic pelvic lymphadenectomy in endometrial cancer (MRC ASTEC trial): a randomised study. Lancet 2009, 373:125-136. the ASTEC study group.
    • (2009) Lancet , vol.373 , pp. 125-136
    • Kitchener, H.1    Swart, A.M.2    Qian, Q.3    Amos, C.4    Parmar, M.K.5
  • 33
    • 79952358569 scopus 로고    scopus 로고
    • Influence of gynecologic oncologists on the survival of patients with endometrial cancer
    • Chan JK, Sherman AE, Kapp DS, et al. Influence of gynecologic oncologists on the survival of patients with endometrial cancer. J Clin Oncol 2011, 29:832-838.
    • (2011) J Clin Oncol , vol.29 , pp. 832-838
    • Chan, J.K.1    Sherman, A.E.2    Kapp, D.S.3
  • 34
    • 81855176025 scopus 로고    scopus 로고
    • Lymphadenectomy influences the utilization of adjuvant radiation treatment for endometrial cancer
    • e1-9.
    • Sharma C, Deutsch I, Lewin SN, et al. Lymphadenectomy influences the utilization of adjuvant radiation treatment for endometrial cancer. Am J Obstet Gynecol 2011, 205:562-569. e1-9.
    • (2011) Am J Obstet Gynecol , vol.205 , pp. 562-569
    • Sharma, C.1    Deutsch, I.2    Lewin, S.N.3
  • 35
    • 84859607775 scopus 로고    scopus 로고
    • Improved survival related to changes in endometrial cancer treatment, a 30-year population based perspective
    • Trovik J, Mauland KK, Werner HM, Wik E, Helland H, Salvesen HB Improved survival related to changes in endometrial cancer treatment, a 30-year population based perspective. Gynecol Oncol 2012, 125:381-387.
    • (2012) Gynecol Oncol , vol.125 , pp. 381-387
    • Trovik, J.1    Mauland, K.K.2    Werner, H.M.3    Wik, E.4    Helland, H.5    Salvesen, H.B.6
  • 36
    • 0842304361 scopus 로고    scopus 로고
    • Prognostic significance and interobserver variability of histologic grading systems for endometrial carcinoma
    • Scholten AN, Smit VT, Beerman H, van Putten WL, Creutzberg CL Prognostic significance and interobserver variability of histologic grading systems for endometrial carcinoma. Cancer 2004, 100:764-772.
    • (2004) Cancer , vol.100 , pp. 764-772
    • Scholten, A.N.1    Smit, V.T.2    Beerman, H.3    van Putten, W.L.4    Creutzberg, C.L.5
  • 37
    • 0033863946 scopus 로고    scopus 로고
    • A binary architectural grading system for uterine endometrial endometrioid carcinoma has superior reproducibility compared with FIGO grading and identifies subsets of advance-stage tumors with favorable and unfavorable prognosis
    • Lax SF, Kurman RJ, Pizer ES, Wu L, Ronnett BM A binary architectural grading system for uterine endometrial endometrioid carcinoma has superior reproducibility compared with FIGO grading and identifies subsets of advance-stage tumors with favorable and unfavorable prognosis. Am J Surg Pathol 2000, 24:1201-1208.
    • (2000) Am J Surg Pathol , vol.24 , pp. 1201-1208
    • Lax, S.F.1    Kurman, R.J.2    Pizer, E.S.3    Wu, L.4    Ronnett, B.M.5
  • 38
    • 79251577132 scopus 로고    scopus 로고
    • Significant variation in the assessment of cervical involvement in endometrial carcinoma: an interobserver variation study
    • McCluggage WG, Hirschowitz L, Wilson GE, Oliva E, Soslow RA, Zaino RJ Significant variation in the assessment of cervical involvement in endometrial carcinoma: an interobserver variation study. Am J Surg Pathol 2011, 35:289-294.
    • (2011) Am J Surg Pathol , vol.35 , pp. 289-294
    • McCluggage, W.G.1    Hirschowitz, L.2    Wilson, G.E.3    Oliva, E.4    Soslow, R.A.5    Zaino, R.J.6
  • 39
    • 0034651530 scopus 로고    scopus 로고
    • The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways
    • Lax SF, Kendall B, Tashiro H, Slebos RJ, Hedrick L The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinoma: evidence of distinct molecular genetic pathways. Cancer 2000, 88:814-824.
    • (2000) Cancer , vol.88 , pp. 814-824
    • Lax, S.F.1    Kendall, B.2    Tashiro, H.3    Slebos, R.J.4    Hedrick, L.5
  • 40
    • 1842506206 scopus 로고    scopus 로고
    • Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification
    • Lax SF Molecular genetic pathways in various types of endometrial carcinoma: from a phenotypical to a molecular-based classification. Virchows Arch 2004, 444:213-223.
    • (2004) Virchows Arch , vol.444 , pp. 213-223
    • Lax, S.F.1
  • 41
    • 0033813298 scopus 로고    scopus 로고
    • Methylation of hMLH1 in a population-based series of endometrial carcinomas
    • Salvesen HB, MacDonald N, Ryan A, et al. Methylation of hMLH1 in a population-based series of endometrial carcinomas. Clin Cancer Res 2000, 6:3607-3613.
    • (2000) Clin Cancer Res , vol.6 , pp. 3607-3613
    • Salvesen, H.B.1    MacDonald, N.2    Ryan, A.3
  • 42
    • 0034667718 scopus 로고    scopus 로고
    • Clinical significance of microsatellite instability in endometrial carcinoma
    • Basil JB, Goodfellow PJ, Rader JS, Mutch DG, Herzog TJ Clinical significance of microsatellite instability in endometrial carcinoma. Cancer 2000, 89:1758-1764.
    • (2000) Cancer , vol.89 , pp. 1758-1764
    • Basil, J.B.1    Goodfellow, P.J.2    Rader, J.S.3    Mutch, D.G.4    Herzog, T.J.5
  • 43
    • 54849432745 scopus 로고    scopus 로고
    • GATA3 expression in estrogen receptor alpha-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival
    • Engelsen IB, Stefansson IM, Akslen LA, Salvesen HB GATA3 expression in estrogen receptor alpha-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival. Am J Obstet Gynecol 2008, 199:543-547.
    • (2008) Am J Obstet Gynecol , vol.199 , pp. 543-547
    • Engelsen, I.B.1    Stefansson, I.M.2    Akslen, L.A.3    Salvesen, H.B.4
  • 44
    • 33744828734 scopus 로고    scopus 로고
    • HER-2 is an independent prognostic factor in endometrial cancer: association with outcome in a large cohort of surgically staged patients
    • Morrison C, Zanagnolo V, Ramirez N, et al. HER-2 is an independent prognostic factor in endometrial cancer: association with outcome in a large cohort of surgically staged patients. J Clin Oncol 2006, 24:2376-2385.
    • (2006) J Clin Oncol , vol.24 , pp. 2376-2385
    • Morrison, C.1    Zanagnolo, V.2    Ramirez, N.3
  • 45
    • 28244490997 scopus 로고    scopus 로고
    • High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma
    • Oda K, Stokoe D, Taketani Y, McCormick F High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma. Cancer Res 2005, 65:10669-10673.
    • (2005) Cancer Res , vol.65 , pp. 10669-10673
    • Oda, K.1    Stokoe, D.2    Taketani, Y.3    McCormick, F.4
  • 46
    • 0032422644 scopus 로고    scopus 로고
    • PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics
    • Risinger JI, Hayes K, Maxwell GL, et al. PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics. Clin Cancer Res 1998, 4:3005-3010.
    • (1998) Clin Cancer Res , vol.4 , pp. 3005-3010
    • Risinger, J.I.1    Hayes, K.2    Maxwell, G.L.3
  • 47
    • 79956000555 scopus 로고    scopus 로고
    • Stathmin overexpression identifies high-risk patients and lymph node metastasis in endometrial cancer
    • the MoMaTec Study Group
    • Trovik J, Wik E, Stefansson IM, et al. Stathmin overexpression identifies high-risk patients and lymph node metastasis in endometrial cancer. Clin Cancer Res 2011, 17:3368-3377. the MoMaTec Study Group.
    • (2011) Clin Cancer Res , vol.17 , pp. 3368-3377
    • Trovik, J.1    Wik, E.2    Stefansson, I.M.3
  • 48
    • 33748805531 scopus 로고    scopus 로고
    • Pathologic expression of p53 or p16 in preoperative curettage specimens identifies high-risk endometrial carcinomas
    • Engelsen IB, Stefansson I, Akslen LA, Salvesen HB Pathologic expression of p53 or p16 in preoperative curettage specimens identifies high-risk endometrial carcinomas. Am J Obstet Gynecol 2006, 195:979-986.
    • (2006) Am J Obstet Gynecol , vol.195 , pp. 979-986
    • Engelsen, I.B.1    Stefansson, I.2    Akslen, L.A.3    Salvesen, H.B.4
  • 49
    • 0033979559 scopus 로고    scopus 로고
    • Loss of nuclear p16 protein expression is not associated with promoter methylation but defines a subgroup of aggressive endometrial carcinomas with poor prognosis
    • Salvesen HB, Das S, Akslen LA Loss of nuclear p16 protein expression is not associated with promoter methylation but defines a subgroup of aggressive endometrial carcinomas with poor prognosis. Clin Cancer Res 2000, 6:153-159.
    • (2000) Clin Cancer Res , vol.6 , pp. 153-159
    • Salvesen, H.B.1    Das, S.2    Akslen, L.A.3
  • 50
    • 2142760943 scopus 로고    scopus 로고
    • Prognostic impact of alterations in P-cadherin expression and related cell adhesion markers in endometrial cancer
    • Stefansson IM, Salvesen HB, Akslen LA Prognostic impact of alterations in P-cadherin expression and related cell adhesion markers in endometrial cancer. J Clin Oncol 2004, 22:1242-1252.
    • (2004) J Clin Oncol , vol.22 , pp. 1242-1252
    • Stefansson, I.M.1    Salvesen, H.B.2    Akslen, L.A.3
  • 51
    • 0036792576 scopus 로고    scopus 로고
    • Beta-catenin and E-cadherin expression patterns in high-grade endometrial carcinoma are associated with histological subtype
    • Schlosshauer PW, Ellenson LH, Soslow RA Beta-catenin and E-cadherin expression patterns in high-grade endometrial carcinoma are associated with histological subtype. Mod Pathol 2002, 15:1032-1037.
    • (2002) Mod Pathol , vol.15 , pp. 1032-1037
    • Schlosshauer, P.W.1    Ellenson, L.H.2    Soslow, R.A.3
  • 52
    • 0345269867 scopus 로고    scopus 로고
    • Abnormalities of E- and P-cadherin and catenin (beta-, gamma-catenin, and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia
    • Moreno-Bueno G, Hardisson D, Sarrió D, et al. Abnormalities of E- and P-cadherin and catenin (beta-, gamma-catenin, and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia. J Pathol 2003, 199:471-478.
    • (2003) J Pathol , vol.199 , pp. 471-478
    • Moreno-Bueno, G.1    Hardisson, D.2    Sarrió, D.3
  • 53
    • 47249122523 scopus 로고    scopus 로고
    • Drug-sensitive FGFR2 mutations in endometrial carcinoma
    • Dutt A, Salvesen HB, Chen TH, et al. Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proc Natl Acad Sci USA 2008, 105:8713-8717.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8713-8717
    • Dutt, A.1    Salvesen, H.B.2    Chen, T.H.3
  • 54
    • 84860456239 scopus 로고    scopus 로고
    • Prognostic importance of DNA ploidy and DNA index in stage I and II endometrioid adenocarcinoma of the endometrium
    • Pradhan M, Abeler VM, Danielsen HE, et al. Prognostic importance of DNA ploidy and DNA index in stage I and II endometrioid adenocarcinoma of the endometrium. Ann Oncol 2012, 23:1178-1184.
    • (2012) Ann Oncol , vol.23 , pp. 1178-1184
    • Pradhan, M.1    Abeler, V.M.2    Danielsen, H.E.3
  • 55
    • 38849154186 scopus 로고    scopus 로고
    • HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas
    • Engelsen IB, Stefansson IM, Beroukhim R, et al. HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas. Int J Oncol 2008, 32:307-316.
    • (2008) Int J Oncol , vol.32 , pp. 307-316
    • Engelsen, I.B.1    Stefansson, I.M.2    Beroukhim, R.3
  • 56
    • 0033932042 scopus 로고    scopus 로고
    • Pretreatment assessment of prognostic indicators in endometrial cancer
    • Mariani A, Sebo TJ, Katzmann JA, et al. Pretreatment assessment of prognostic indicators in endometrial cancer. Am J Obstet Gynecol 2000, 182:1535-1544.
    • (2000) Am J Obstet Gynecol , vol.182 , pp. 1535-1544
    • Mariani, A.1    Sebo, T.J.2    Katzmann, J.A.3
  • 57
    • 70749115766 scopus 로고    scopus 로고
    • Deoxyribonucleic acid ploidy in endometrial carcinoma: a reproducible and valid prognostic marker in a routine diagnostic setting
    • Wik E, Trovik J, Iversen OE, et al. Deoxyribonucleic acid ploidy in endometrial carcinoma: a reproducible and valid prognostic marker in a routine diagnostic setting. Am J Obstet Gynecol 2009, 201:603-607.
    • (2009) Am J Obstet Gynecol , vol.201 , pp. 603-607
    • Wik, E.1    Trovik, J.2    Iversen, O.E.3
  • 58
    • 0027396974 scopus 로고
    • Prognostic significance of hormone receptors in endometrial cancer
    • Creasman WT Prognostic significance of hormone receptors in endometrial cancer. Cancer 1993, 71(suppl):1467-1470.
    • (1993) Cancer , vol.71 , Issue.SUPPL. , pp. 1467-1470
    • Creasman, W.T.1
  • 59
    • 34447643260 scopus 로고    scopus 로고
    • Relationship of estrogen and progesterone receptors to clinical outcome in metastatic endometrial carcinoma: a Gynecologic Oncology Group Study
    • Singh M, Zaino RJ, Filiaci VJ, Leslie KK Relationship of estrogen and progesterone receptors to clinical outcome in metastatic endometrial carcinoma: a Gynecologic Oncology Group Study. Gynecol Oncol 2007, 106:325-333.
    • (2007) Gynecol Oncol , vol.106 , pp. 325-333
    • Singh, M.1    Zaino, R.J.2    Filiaci, V.J.3    Leslie, K.K.4
  • 60
    • 0022536523 scopus 로고
    • Prediction of clinical outcome with estrogen and progestin receptor concentrations and their relationships to clinical and histopathological variables in endometrial cancer
    • Kauppila AJ, Isotalo HE, Kivinen ST, Vihko RK Prediction of clinical outcome with estrogen and progestin receptor concentrations and their relationships to clinical and histopathological variables in endometrial cancer. Cancer Res 1986, 46:5380-5384.
    • (1986) Cancer Res , vol.46 , pp. 5380-5384
    • Kauppila, A.J.1    Isotalo, H.E.2    Kivinen, S.T.3    Vihko, R.K.4
  • 62
    • 1842582530 scopus 로고    scopus 로고
    • A significance of immunohistochemical determination of steroid receptors, cell proliferation factor Ki-67 and protein p53 in endometrial carcinoma
    • Oreskovic S, Babic D, Kalafatic D, Barisic D, Beketic-Oreskovic L A significance of immunohistochemical determination of steroid receptors, cell proliferation factor Ki-67 and protein p53 in endometrial carcinoma. Gynecol Oncol 2004, 93:34-40.
    • (2004) Gynecol Oncol , vol.93 , pp. 34-40
    • Oreskovic, S.1    Babic, D.2    Kalafatic, D.3    Barisic, D.4    Beketic-Oreskovic, L.5
  • 63
    • 0023021498 scopus 로고
    • Flow cytometric deoxyribonucleic acid index: a prognostic factor in endometrial carcinoma
    • Iversen OE Flow cytometric deoxyribonucleic acid index: a prognostic factor in endometrial carcinoma. Am J Obstet Gynecol 1986, 155:770-776.
    • (1986) Am J Obstet Gynecol , vol.155 , pp. 770-776
    • Iversen, O.E.1
  • 64
    • 33847385938 scopus 로고    scopus 로고
    • Ten-year results of a prospective study on the prognostic role of ploidy in endometrial carcinoma: dNA aneuploidy identifies high-risk cases among the so-called 'low-risk' patients with well and moderately differentiated tumors
    • Susini T, Amunni G, Molino C, et al. Ten-year results of a prospective study on the prognostic role of ploidy in endometrial carcinoma: dNA aneuploidy identifies high-risk cases among the so-called 'low-risk' patients with well and moderately differentiated tumors. Cancer 2007, 109:882-890.
    • (2007) Cancer , vol.109 , pp. 882-890
    • Susini, T.1    Amunni, G.2    Molino, C.3
  • 65
    • 2642557954 scopus 로고    scopus 로고
    • Prognostic impact of histological grade and vascular invasion compared with tumour cell proliferation in endometrial carcinoma of endometrioid type
    • Stefansson IM, Salvesen HB, Immervoll H, Akslen LA Prognostic impact of histological grade and vascular invasion compared with tumour cell proliferation in endometrial carcinoma of endometrioid type. Histopathology 2004, 44:472-479.
    • (2004) Histopathology , vol.44 , pp. 472-479
    • Stefansson, I.M.1    Salvesen, H.B.2    Immervoll, H.3    Akslen, L.A.4
  • 66
    • 0032896335 scopus 로고    scopus 로고
    • Prognostic significance of angiogenesis and Ki-67, p53, and p21 expression: a population-based endometrial carcinoma study
    • Salvesen HB, Iversen OE, Akslen LA Prognostic significance of angiogenesis and Ki-67, p53, and p21 expression: a population-based endometrial carcinoma study. J Clin Oncol 1999, 17:1382-1390.
    • (1999) J Clin Oncol , vol.17 , pp. 1382-1390
    • Salvesen, H.B.1    Iversen, O.E.2    Akslen, L.A.3
  • 67
    • 4143100453 scopus 로고    scopus 로고
    • Her-2/neu overexpression and amplification in uterine papillary serous carcinoma
    • Slomovitz BM, Broaddus RR, Burke TW, et al. Her-2/neu overexpression and amplification in uterine papillary serous carcinoma. J Clin Oncol 2004, 22:3126-3132.
    • (2004) J Clin Oncol , vol.22 , pp. 3126-3132
    • Slomovitz, B.M.1    Broaddus, R.R.2    Burke, T.W.3
  • 69
    • 34250687198 scopus 로고    scopus 로고
    • Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity
    • Saal LH, Johansson P, Holm K, et al. Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity. Proc Natl Acad Sci USA 2007, 104:7564-7569.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 7564-7569
    • Saal, L.H.1    Johansson, P.2    Holm, K.3
  • 70
    • 66649102458 scopus 로고    scopus 로고
    • Stathmin and tubulin expression and survival of ovarian cancer patients receiving platinum treatment with and without paclitaxel
    • Su D, Smith SM, Preti M, et al. Stathmin and tubulin expression and survival of ovarian cancer patients receiving platinum treatment with and without paclitaxel. Cancer 2009, 115:2453-2463.
    • (2009) Cancer , vol.115 , pp. 2453-2463
    • Su, D.1    Smith, S.M.2    Preti, M.3
  • 71
    • 79960390271 scopus 로고    scopus 로고
    • Elevated plasma growth differentiation factor-15 correlates with lymph node metastases and poor survival in endometrial cancer
    • Staff AC, Trovik J, Eriksson AG, et al. Elevated plasma growth differentiation factor-15 correlates with lymph node metastases and poor survival in endometrial cancer. Clin Cancer Res 2011, 17:4825-4833.
    • (2011) Clin Cancer Res , vol.17 , pp. 4825-4833
    • Staff, A.C.1    Trovik, J.2    Eriksson, A.G.3
  • 72
    • 84859415553 scopus 로고    scopus 로고
    • Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer
    • Brooks AN, Kilgour E, Smith PD Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer. Clin Cancer Res 2012, 18:1855-1862.
    • (2012) Clin Cancer Res , vol.18 , pp. 1855-1862
    • Brooks, A.N.1    Kilgour, E.2    Smith, P.D.3
  • 73
    • 84863338519 scopus 로고    scopus 로고
    • PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations
    • Janku F, Wheler JJ, Westin SN, et al. PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations. J Clin Oncol 2012, 30:777-782.
    • (2012) J Clin Oncol , vol.30 , pp. 777-782
    • Janku, F.1    Wheler, J.J.2    Westin, S.N.3
  • 74
    • 34447264769 scopus 로고    scopus 로고
    • Biomarker-adaptive threshold design: a procedure for evaluating treatment with possible biomarker-defined subset effect
    • Jiang W, Freidlin B, Simon R Biomarker-adaptive threshold design: a procedure for evaluating treatment with possible biomarker-defined subset effect. J Natl Cancer Inst 2007, 99:1036-1043.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 1036-1043
    • Jiang, W.1    Freidlin, B.2    Simon, R.3
  • 75
    • 84856303989 scopus 로고    scopus 로고
    • Stratification based on high tumour cell content in fresh frozen tissue promotes selection of aggressive endometrial carcinomas
    • Halle MK, Werner HM, Krakstad C, et al. Stratification based on high tumour cell content in fresh frozen tissue promotes selection of aggressive endometrial carcinomas. Histopathology 2012, 60:516-519.
    • (2012) Histopathology , vol.60 , pp. 516-519
    • Halle, M.K.1    Werner, H.M.2    Krakstad, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.