Magnetic resonance lymphography: A novel technique for lymph node assessment in gynecologic malignancies

Cancer Biomarkers

Volumn 5, Issue 2, 2009, Pages 81-88

  Narayanana, Priya ^a,c   Iyngkarana, T ^a   Sohaibb, S A ^b   Rezneka, R H ^a   Rockalla, A G ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b ROYAL MARSDEN HOSPITAL   (United Kingdom)

^c Academic Department of Radiology   (United Kingdom)

Author keywords

Gynecologic imaging; Magnetic resonance lymphography (MRL); Nanoparticles

Indexed keywords

FERUMOXTRAN 10; FLUORODEOXYGLUCOSE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE; UNCLASSIFIED DRUG;

ARTICLE; BACKACHE; CANCER STAGING; CANCER SURVIVAL; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; DIAGNOSTIC PROCEDURE; DIFFUSION WEIGHTED IMAGING; DRUG ERUPTION; DRUG INDUCED HEADACHE; DRUG TOLERABILITY; DRUG UPTAKE; ENDOMETRIUM CANCER; ERYTHEMA; HOT FLUSH; HUMAN; INGUINAL LYMPH NODE; LYMPH NODE METASTASIS; LYMPHADENECTOMY; LYMPHOGRAPHY; MAGNETIC RESONANCE LYMPHOGRAPHY; MUSCLE CRAMP; NANOIMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROGNOSIS; SENSITIVITY AND SPECIFICITY; UTERINE CERVIX CANCER; VULVA CANCER;

CLINICAL TRIALS AS TOPIC; FEMALE; GENITAL NEOPLASMS, FEMALE; HUMANS; IRON; LYMPH NODES; LYMPHOGRAPHY; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; OXIDES; POSITRON-EMISSION TOMOGRAPHY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 65549114650     PISSN: 15740153     EISSN: None     Source Type: Journal    
DOI: 10.3233/CBM-2009-0543     Document Type: Article

References (32)

1. S.J. Vinnicombe, A.R. Norman, V. Nicolson and J.E. Husband, Normal pelvic lymph nodes: Evaluation with CT after bipedal lymphography, Radiology 194 (1995), 349-355.
2. W.T. Yang, W.W. Lam, M.Y. Yu, T.H. Cheung and C. Metreweli, Comparison of dynamic helical CT and dynamic MR imaging in the evaluation of pelvic lymph nodes in cervical carcinoma, AJR 175 (2003), 759-766.
3. G. Brown, C.J. Richards, M.W. Bourne et al., Morphologic predictors of lymph node status in rectal cancer with use of high spatial resolution MR imaging with histopathologic comparison, Radiology 227 (2003), 371-377.
4. D.M. Koh, M. Hughes and J.E. Husband, Cross-sectional imaging of nodal metastases in the abdomen and pelvis, Abdominal Imaging 31 (6) (2006), 632-643.
5. A.D. Williams, C. Cousins, W.P. Soutter et al., Detection of pelvic lymph node metastases in gynaecological malignancy: A comparison of CT, MR imaging and positron emission tomography, AJR 177 (2001), 343-348.
6. H. Kaur, P.M. Silverman, R.B. Iyer et al., Diagnosis, staging and surveillance of cervical carcinoma, AJR 180 (2003), 1621-1631.
7. T. Inoue and K. Morita, The prognostic significance of number of positive nodes in cervical carcinoma stages IB, IIA and IIB, Cancer 55 (1990), 1923-1927.
8. T. Kamura, N. Tsukamoto, N. Tsuruchi et al., Multivariate analysis of the histopathologic prognostic factors of cervical cancer in patients undergoing radical hysterectomy, Cancer 69 (1992), 1923-1927.
9. L.D. Lagasse, W.T. Creasman, H.M. Shingleton, J.H. Ford and Blessing, Results and complications of operative staging in cervical cancer: experience of the Gynecologic Oncology Group, Gynecol Oncol 9 (1) (1980), 90-98.
10. D. Cavanagh and M.S. Hoffman, Controversies in the management of vulvar carcinoma, Br J Obstet Gynaecol 103 (1996), 293-300.
11. M. Harisinghani, M.A. Saksena and P.F. Hahn, Ferumoxtran-10-Enhanced MR Lymphangiography: Does contrast-enhanced imaging alone suffice for accurate lymph node characterisation, AJR 186 (2006), 144-148.
12. M. Saksena, M. Harisinghani, P.F. Hahn et al., Comparison of Lymphotropic Nanoparticle-Enhanced MRI Sequences in Patients with various primary cancers, AJR 187 (2006), W582-W588.
13. M. Harisinghani, J. Barentsz, P.F. Hahn et al., Noninvasive detection of clinically occult lymph node metastases in prostate cancer, NEJM 348(25) (2003), 2491-2499.
14. Y. Anzai, C.W. Piccoli, E.K. Outwater et al., Evaluation of neck and body metastases to nodes with ferumoxtran 10-enhanced MR imaging:pHase III safety and efficacy study, Radiology 228 (2003), 777-788.
15. A.G. Rockall, S.A. Sohaib, M. Harisinghani et al., Diagnostic performance of nanoparticle enhanced magnetic resonance imaging in the diagnosis of lymph node metastases in patients with endometrial and cervical cancer, J Clin Onc 23(12) (2005), 813-2821.
16. D.M. Koh, G. Brown, L. Temple et al., Rectal cancer: Mesorectal lymph nodes at MR imaging with USPIO versus histopathologic findings - initial observations, Radiology 231 (2004), 91-99.
17. M.A. Saksena, A. Saokar and M. Harisinghani, Lymphotropic nanoparticle enhanced MR imaging (LNMRI) technique for lymph node imaging, Eur J Rad 58 (2006), 367-364.
18. T. Iyngkaran, P. Narayanan, S.A. Sohaib et al., Pearls and pitfalls of magnetic resonance lymphography. RSNA 93rd Scientific Assembly and Annual Meeting 2007, Chicago:947 (LLOB2712).
19. T.M. Keller, S.C. Michel, J. Frohlich et al., USPIO enhanced MRI for preoperative staging of gynaecological pelvic tumours: Preliminary results, Eur Radiol 14 (2004), 937-944.
20. O. Will, S. Purkaysatha, C. Chan et al., Diagnostic precision of nanoparticle-enhanced MRI for lymph node metastases: A meta-analysis, Lancet Oncol 7(1) (2006), 52-60.
21. R. Weissleder, G. Elizondo, J. Wittenberg et al., Ultrasmall superparamagnetic iron oxide: An intravenous contrast agent for assessing lymph nodes with MR imaging, Radiology 175 (1990), 494-498.
22. M. Bellin, C. Roy, K. Kinkel et al., Lymph node metastases: Safety and effectiveness of MR imaging with ultrasmall superparamagnetic iron oxide particles - Initial Clinical Experience, Radiology 207 (1998), 799-808.
23. S.C. Michel, T.M. Keller, J.M. Frohlich et al., Preoperative breast cancer staging: MR imaging of the axilla with ultrasmall superparamagnetic iron oxide enhancement, Radiology 225 (2002), 527-536.
24. A. Laghi, P. Paolantonio, V. Panebianco et al., Decrease of signal intensity of myometrium and cervical stroma after ultrasmall superparamagnetic iron oxide (USPIO) particles administration, Invest Radiol 39(11) (2004), 666-670.
25. N. Pierce, S.A. Sohaib, A. Rockall et al., MRI appearances of primary vulval cancer following MRL, Cancer Imaging 7 (2007), S159.
26. H.H. Chou, T.C. Chang, T.C. Yen et al., Low value of [18F] -fluro -2-deoxy-D-glucose positron emission tomography in primary staging of early stage cervical cancer before radical hysterectomy, J Clin Onc 24(1) (2006), 128-128.
27. H.J. Choi, J.W. Roh, S.-S.Seo et al., Comparison of the accuracy of magnetic resonance imaging and positron emission tomography/computed tomography in the presurgical detection of lymph node metastases in patients with uterine cervical carcinoma. A prospective study, Cancer 24(1) (2006), 123-128.
28. A.L. Loft, A.K. Berthelsen, H. Roed et al., The diagnostic value of PET/ CT scanning in patients with cervical cancer: A prospectice study, Gynae Oncol 106 (2007), 29-34.
29. S.H. Choi, W.K. Moon and J.H. Hong, Lymph node metastasis: Ultrasmall superparamagnetic iron oxide - enhanced MR imaging versus PET/CT in a rabbit model, Radiology 242(1) (2007), 137-143.
30. http://www.acrin.org.
31. A.F. Burnett, L.D. Roman, A.T. O'Meara et al., Radical vaginal trachelectomy and pelvic lymphadenectomy for preservation of fertility in early cervical carcinoma, Gynecol Oncol 88(3) (2003), 419-423.
32. A. Taylor, A.G. Rockall, R.H. Reznek and M.E. Powell, Mapping pelvic lymph nodes: Guidelines for delineation in intensity-modulated radiotherapy, Int J Oncol Biol Phys 63(5) (2005), 1604-1612.