Clinical significance of microsatellite instability in endometrial carcinoma

Cancer

Volumn 89, Issue 8, 2000, Pages 1758-1764

  Basil, Jack B ^a   Goodfellow, Paul J ^a,b   Rader, Janet S ^a   Mutch, David G ^a   Herzog, Thomas J ^a,b  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Clinicopathologic factors; Endometrial carcinoma; Microsatellite instability

Indexed keywords

MICROSATELLITE DNA;

ARTICLE; CALCULATION; CANCER RECURRENCE; CANCER STAGING; ENDOMETRIUM CANCER; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; STATISTICAL ANALYSIS; SURVIVAL RATE;

DNA, NEOPLASM; ENDOMETRIAL NEOPLASMS; FEMALE; GENETIC MARKERS; HUMAN; HYSTERECTOMY; MICROSATELLITE REPEATS; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; OVARIECTOMY; RACIAL STOCKS; RECURRENCE; SUPPORT, U.S. GOV'T, P.H.S.; SURVIVAL ANALYSIS;

EID: 0034667718     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0142(20001015)89:8<1758::AID-CNCR16>3.0.CO;2-A     Document Type: Article

References (39)

1. Cancer statistics 2000
2. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: An updated review
3. Hypermutability and mismatch repair deficiency in RER+ tumor cells
4. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
5. Mutations of mutS homolog in hereditary nonpolyposis colorectal cancer
6. Mutation of mutL homolog in hereditary colon cancer
7. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer
8. Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer
9. Microsatellite instability: Impact on cancer progression in proximal and distal colorectal cancers
10. Replication error in colorectal carcinoma: Association with loss of heterozygosity at mismatch repair loci and clinicopathological variables
11. Tumor microsatellite instability and clinical outcome in young patients with colorectal cancer
12. Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers
13. Genetic instability of microsatellites in endometrial carcinoma
14. Microsatellite instability in endometrial carcinoma
15. Allelic loss of sequences from the long arm of chromosome 10 and replication errors in endometrial cancers
16. Microsatellite instability in sporadic endometrial carcinoma
17. The frequency of p53, K-ras mutations, and microsatellite instability differs in uterine endometrioid and serous carcinomas
18. Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma
19. Microsatellite instability in endometrial carcinomas: Clinicopathologic correlations in a series of 42 cases
20. Microsatellite instability in endometrial cancer: Relation to histologic subtypes
21. A simple salting out procedure for extracting DNA from human nucleated cells
22. A rapid nonenzymatic method for the preparation of HMW DNA from blood for RFLP studies
23. Mutational analysis of MLH1 and MSH2 in 25 prospectively-acquired RER + endometrial cancers
24. A national cancer institute workshop on microsatellite instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
25. FIGO stages: 1988 Revision
26. A genetic model for colorectal tumorigenesis
27. Lessons from hereditary colorectal cancer
28. Race and clinical outcome in endometriai carcinoma
29. Uterine papillary serous carcinoma: Patterns of metastatic spread
30. Surgical pathologic spread patterns of endometrial cancer. A Gynecologic Oncology Group study
31. Recurrent adenocarcinoma of the endometrium: A clinical and histopathological study of 379 patients
32. Frequency and prognostic impact of microsatellite instability in a large population-based study of endometrial carcinomas
33. MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers
34. MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas
35. hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents
36. Dependence on RAD52 and RAD1 for anti-cancer drug resistance mediated by inactivation of mismatch repair genes
37. A role for methylation of the hMLH1 promoter in loss of hMLH1 expression and drug resistance in ovarian cancer
38. The role of hMLH1, hMSH3, and hMSH6 defects in cisplatin and oxaliplatin resistance: Correlation with replicative bypass of platinum-DNA adducts
39. The role of DNA mismatch repair in platinum drug resistance