Folate deprivation enhances invasiveness of human colon cancer cells mediated by activation of sonic hedgehog signaling through promoter hypomethylation and cross action with transcription nuclear factor-kappa B pathway

Carcinogenesis

Volumn 33, Issue 6, 2012, Pages 1158-1168

  Wang, Tz Ping ^a   Hsu, Shu Han ^a   Feng, Hsin Chun ^a   Huang, Rwei Fen S ^a  

^a FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; CYCLOPAMINE; FOLIC ACID; GELATINASE A; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN PATCHED; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR SNAIL; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN;

ARTICLE; CANCER INVASION; CARCINOMA CELL; CELL INVASION; CELL MIGRATION; COLON CARCINOGENESIS; COLON CARCINOMA; CONTROLLED STUDY; DNA BINDING; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN METHYLATION; SIGNAL TRANSDUCTION;

ANTIGENS, CD29; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; DNA; DNA METHYLATION; EPITHELIAL-MESENCHYMAL TRANSITION; FOLIC ACID DEFICIENCY; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; I-KAPPA B KINASE; MATRIX METALLOPROTEINASE 2; NEOPLASM INVASIVENESS; NF-KAPPA B; NITRILES; PROMOTER REGIONS, GENETIC; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; SULFONES; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA; VERATRUM ALKALOIDS;

EID: 84864293976     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs138     Document Type: Article

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