Exogenous and endogenous ghrelin counteracts GLP-1 action to stimulate cAMP signaling and insulin secretion in islet β-cells

FEBS Letters

Volumn 586, Issue 16, 2012, Pages 2555-2562

  Damdindorj, Boldbaatar ^a   Dezaki, Katsuya ^a   Kurashina, Tomoyuki ^a   Sone, Hideyuki ^a   Rita, Rauza ^a   Kakei, Masafumi ^a   Yada, Toshihiko ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

cAMP; Cytosolic Ca 2+; Ghrelin; GLP 1; Insulin release; Islet cell

Indexed keywords

CALCIUM ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; GHRELIN; GLUCAGON LIKE PEPTIDE 1; GLUCOSE;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; ENZYME INHIBITION; INSULIN LIKE ACTIVITY; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; ANIMALS; CALCIUM; CYCLIC AMP; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; GHRELIN; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MODELS, BIOLOGICAL; RATS; RATS, WISTAR; TIME FACTORS;

RATTUS;

EID: 84864289974     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.06.034     Document Type: Article

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