-
1
-
-
78651247731
-
Genome-wide analysis of copy number variants in age-related macular degeneration
-
Meyer KJ, Davis LK, Schindler EI, Beck JS, Rudd DS, Grundstad AJ, Scheetz TE, Braun TA, Fingert JH, Alward WL, Kwon YH, Folk JC, Russell SR, Wassink TH, Stone EM, Sheffield VC (2010) Genome-wide analysis of copy number variants in age-related macular degeneration. Hum Genet 129:91-100
-
(2010)
Hum Genet
, vol.129
, pp. 91-100
-
-
Meyer, K.J.1
Davis, L.K.2
Schindler, E.I.3
Beck, J.S.4
Rudd, D.S.5
Grundstad, A.J.6
Scheetz, T.E.7
Braun, T.A.8
Fingert, J.H.9
Alward, W.L.10
Kwon, Y.H.11
Folk, J.C.12
Russell, S.R.13
Wassink, T.H.14
Stone, E.M.15
Sheffield, V.C.16
-
2
-
-
16244368037
-
Risk factors for the incidence of advanced age-related macular degeneration in the Age-Related Eye Disease Study (AREDS): AREDS report no. 19
-
DOI 10.1016/j.ophtha.2004.10.047, PII S0161642004017944
-
Clemons TE, Milton RC, Klein R, Seddon JM, Ferris FL 3rd (2005) Age-related eye disease study research group. Risk factors for the incidence of advanced age-related macular degeneration in the age-related eye disease study (AREDS) AREDS report no. 19. Ophthalmology 112:533-539 (Pubitemid 41108849)
-
(2005)
Ophthalmology
, vol.112
, Issue.4
, pp. 533-539
-
-
Milton, R.C.1
Clemons, T.E.2
Klien, R.3
Seddon, J.M.4
Ferris III, F.L.5
-
3
-
-
84860257625
-
-
World Health Organization (WHO) Accessed October 2009
-
World Health Organization (WHO). Priority eye diseases.http://www.who. int/blindness/causes/priority/en/index8.html. Accessed October 2009
-
Priority Eye Diseases
-
-
-
4
-
-
33751103471
-
Age-related macular degeneration - Emerging pathogenetic and therapeutic concepts
-
DOI 10.1080/07853890600946724, PII P30P0084J262W715
-
Gehrs KM, Anderson DH, Johnson LV, Hageman GS (2006) Age-related macular degeneration emerging pathogenetic and therapeutic concepts. Ann Med 38:450-471 (Pubitemid 44767496)
-
(2006)
Annals of Medicine
, vol.38
, Issue.7
, pp. 450-471
-
-
Gehrs, K.M.1
Anderson, D.H.2
Johnson, L.V.3
Hageman, G.S.4
-
5
-
-
77954686229
-
-
National Eye Institute, US National Institutes Of Health Accessed August 2010
-
National Eye Institute, US National Institutes of Health. Facts about age-related macular degeneration. http://www.nei.nih.gov/health/maculardegen/ armd-facts.asp. Accessed August 2010
-
Facts about Age-related Macular Degeneration
-
-
-
8
-
-
0022585542
-
Retinal pigment epithelial lipofuscin and melanin and choroidal melanin in human eyes
-
Weiter JJ, Delori FC, Wing GL, Fitch KA (1986) Retinal pigment epithelial lipofuscin and melanin and choroidal melanin in human eyes. Invest Ophthalmol Vis Sci 27:145-152 (Pubitemid 16129780)
-
(1986)
Investigative Ophthalmology and Visual Science
, vol.27
, Issue.2
, pp. 145-152
-
-
Weiter, J.J.1
Delori, F.C.2
Wing, G.L.3
Fitch, K.A.4
-
9
-
-
48149112109
-
Prevalence and risk factors for age-related macular degeneration in an adult japanese population: The fun-agata study
-
Kawasaki R, Wang JJ, Ji GJ, Taylor B, Oizumi T, Daimon M, Kato T, Kawata S, Kayama T, Tano Y, Mitchell P, Yamashita H, Wong TY (2008) Prevalence and risk factors for age-related macular degeneration in an adult Japanese population: the Fun-agata study. Ophthalmology 115:1376-1381
-
(2008)
Ophthalmology
, vol.115
, pp. 1376-1381
-
-
Kawasaki, R.1
Wang, J.J.2
Ji, G.J.3
Taylor, B.4
Oizumi, T.5
Daimon, M.6
Kato, T.7
Kawata, S.8
Kayama, T.9
Tano, Y.10
Mitchell, P.11
Yamashita, H.12
Wong, T.Y.13
-
10
-
-
77953928470
-
Analysis of single nucleotide polymorphisms in the nos2a gene and interaction with smoking in age-related macular degeneration
-
Ayala-Haedo JA, Gallins PJ, Whitehead PL, Schwartz SG, Kov-ach JL, Postel EA, Agarwal A, Wang G, Haines JL, Pericak-Vance MA, Scott WK (2010) Analysis of single nucleotide polymorphisms in the NOS2A gene and interaction with smoking in age-related macular degeneration. Ann Hum Genet 74:195-201
-
(2010)
Ann Hum Genet
, vol.74
, pp. 195-201
-
-
Ayala-Haedo, J.A.1
Gallins, P.J.2
Whitehead, P.L.3
Schwartz, S.G.4
Kov-Ach, J.L.5
Postel, E.A.6
Agarwal, A.7
Wang, G.8
Haines, J.L.9
Pericak-Vance, M.A.10
Scott, W.K.11
-
11
-
-
0032921559
-
Can antioxidant vitamins materially reduce oxidative damage in humans?
-
DOI 10.1016/S0891-5849(98)00302-5, PII S0891584998003025
-
McCall MR, Frei B (1999) Can antioxidant vitamins materially reduce oxidative damage in humans? Free Radic Biol Med 26: 1034-1053 (Pubitemid 29198377)
-
(1999)
Free Radical Biology and Medicine
, vol.26
, Issue.7-8
, pp. 1034-1053
-
-
McCall, M.R.1
Frei, B.2
-
13
-
-
79952112401
-
Oxidation and age-related mac-ular degeneration: Insights from molecular biology
-
Khandhadia S, Lotery A (2010) Oxidation and age-related mac-ular degeneration: insights from molecular biology. Expert Rev Mol Med 12:e34
-
(2010)
Expert Rev Mol Med
, vol.12
-
-
Khandhadia, S.1
Lotery, A.2
-
14
-
-
72449197100
-
Oxidative macromolecular damage in age-related macular degeneration
-
Totan Y, Yaǧci R, Bardak Y, Ozyurt H, Kendir F, Yilmaz G, Sahin S, Sahin Tiǧ U (2009) Oxidative macromolecular damage in age-related macular degeneration. Curr Eye Res 34:1089-1093
-
(2009)
Curr Eye Res
, vol.34
, pp. 1089-1093
-
-
Totan, Y.1
Yaǧci, R.2
Bardak, Y.3
Ozyurt, H.4
Kendir, F.5
Yilmaz, G.6
Sahin, S.7
Sahin Tig, U.8
-
15
-
-
37349032828
-
Iron toxicity as a potential factor in AMD
-
DOI 10.1097/IAE.0b013e318074c290, PII 0000698220071000000001
-
Wong RW, Richa DC, Hahn P, Green WR, Dunaief JL (2007) Iron toxicity as a potential factor in AMD. Retina 27:997-1003 (Pubitemid 350303998)
-
(2007)
Retina
, vol.27
, Issue.8
, pp. 997-1003
-
-
Wong, R.W.1
Richa, D.C.2
Hahn, P.3
Green, W.R.4
Dunaief, J.L.5
-
16
-
-
79955038329
-
Implications of altered iron homeostasis for age-related macular degeneration
-
Blasiak J, Szaflik J, Szaflik JP (2011) Implications of altered iron homeostasis for age-related macular degeneration. Front Biosci 16:1551-1559
-
(2011)
Front Biosci
, vol.16
, pp. 1551-1559
-
-
Blasiak, J.1
Szaflik, J.2
Szaflik, J.P.3
-
17
-
-
33845638434
-
Iron levels in human retina: Sex difference and increase with age
-
DOI 10.1097/WNR.0b013e3280107776, PII 0000175620061127000010
-
Hahn P, Ying GS, Beard J, Dunaief JL (2006) Iron levels in human retina: sex difference and increase with age. Neuroreport 17:1803-1806 (Pubitemid 44948111)
-
(2006)
NeuroReport
, vol.17
, Issue.17
, pp. 1803-1806
-
-
Hahn, P.1
Ying, G.-S.2
Beard, J.3
Dunaief, J.L.4
-
19
-
-
0036097438
-
Risk factors for age-related macular degeneration: An update
-
DOI 10.1097/00055735-200206000-00007
-
Hyman L, Neborsky R (2002) Risk factors for age-related mac-ular degeneration: an update. Curr Opin Ophthalmol 13:171-175 (Pubitemid 34518202)
-
(2002)
Current Opinion in Ophthalmology
, vol.13
, Issue.3
, pp. 171-175
-
-
Hyman, L.1
Neborsky, R.2
-
20
-
-
33846935944
-
An update on the genetics of age-related macular degeneration
-
Scholl HP, Fleckenstein M, Charbel IP, Keilhauer C, Holz FG, Weber BH (2007) An update on the genetics of age-related macular degeneration. Mol Vis 13:196-205 (Pubitemid 46232110)
-
(2007)
Molecular Vision
, vol.13
, pp. 196-205
-
-
Scholl, H.P.N.1
Fleckenstein, M.2
Issa, P.C.3
Keilhauer, C.4
Holz, F.G.5
Weber, B.H.F.6
-
21
-
-
14944364782
-
The US twin study of age-related macular degeneration: Relative roles of genetic and environmental influences
-
DOI 10.1001/archopht.123.3.321
-
Seddon JM, Cote J, Page WF, Aggen SH, Neale MC (2005) The US twin study of age-related macular degeneration: relative roles of genetic and environmental influences. Arch Ophthalmol 123: 321-327 (Pubitemid 41007575)
-
(2005)
Archives of Ophthalmology
, vol.123
, Issue.3
, pp. 321-327
-
-
Seddon, J.M.1
Cote, J.2
Page, W.F.3
Aggen, S.H.4
Neale, M.C.5
-
22
-
-
0032438352
-
Genetic risk of age-related maculopathy: Population-based familial aggregation study
-
Klaver CC, Wolfs RC, Assink JJ, van Duijn CM, Hofman A, de Jong PT (1998) Genetic risk of age-related maculopathy population-based familial aggregation study. Arch Ophthalmol 116: 1646-1651 (Pubitemid 29001964)
-
(1998)
Archives of Ophthalmology
, vol.116
, Issue.12
, pp. 1646-1651
-
-
Klaver, C.C.W.1
Wolfs, R.C.W.2
Assink, J.J.M.3
Van Duijn, C.M.4
Hofman, A.5
De Jong, P.T.V.M.6
-
23
-
-
34247470278
-
Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration
-
DOI 10.1001/jama.297.16.1793
-
Seddon JM, Francis PJ, George S, Schultz DW, Rosner B, Klein ML (2007) Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration. JAMA 297:1793-1800 (Pubitemid 46658648)
-
(2007)
Journal of the American Medical Association
, vol.297
, Issue.16
, pp. 1793-1800
-
-
Seddon, J.M.1
Francis, P.J.2
George, S.3
Schultz, D.W.4
Rosner, B.5
Klein, M.L.6
-
25
-
-
38749154667
-
Familial aggregation of age-related macular degeneration in the Utah population
-
DOI 10.1016/j.visres.2007.11.013, PII S004269890700510X
-
Luo L, Harmon J, Yang X, Chen H, Patel S, Mineau G, Yang Z, Constantine R, Buehler J, Kaminoh Y, Ma X, Wong TY, Zhang M, Zhang K (2008) Familial aggregation of age-related macular degeneration in the Utah population. Vis Res 48:494-500 (Pubitemid 351179527)
-
(2008)
Vision Research
, vol.48
, Issue.3
, pp. 494-500
-
-
Luo, L.1
Harmon, J.2
Yang, X.3
Chen, H.4
Patel, S.5
Mineau, G.6
Yang, Z.7
Constantine, R.8
Buehler, J.9
Kaminoh, Y.10
Ma, X.11
Wong, T.Y.12
Zhang, M.13
Zhang, K.14
-
26
-
-
70350572321
-
Association between vascular endo-thelial growth factor gene polymorphisms and age-related mac-ular degeneration in a polish population
-
Janik-Papis K, Zaras M, Krzyzanowska A, Wozniak K, Blasiak J, Szaflik J, Szaflik JP (2009) Association between vascular endo-thelial growth factor gene polymorphisms and age-related mac-ular degeneration in a Polish population. Exp Mol Pathol 87(3):234-238
-
(2009)
Exp Mol Pathol
, vol.87
, Issue.3
, pp. 234-238
-
-
Janik-Papis, K.1
Zaras, M.2
Krzyzanowska, A.3
Wozniak, K.4
Blasiak, J.5
Szaflik, J.6
Szaflik, J.P.7
-
27
-
-
79951813768
-
Polymorphisms in arms2 (LOC387715) and loxl1 genes in the japanese with age-related macular degeneration
-
Fuse N, Mengkegale M, Miyazawa A, Abe T, Nakazawa T, Wakusawa R, Nishida K (2011) Polymorphisms in ARMS2 (LOC387715) and LOXL1 genes in the Japanese with age-related macular degeneration. Am J Ophthalmol 151:550-556
-
(2011)
Am J Ophthalmol
, vol.151
, pp. 550-556
-
-
Fuse, N.1
Mengkegale, M.2
Miyazawa, A.3
Abe, T.4
Nakazawa, T.5
Wakusawa, R.6
Nishida, K.7
-
28
-
-
78650868796
-
Glutathione s-transferase m1, gstt1 and gstp1 genetic polymorphisms and the risk of age-related macular degeneration
-
Güven M, Görgün E, Unal M, Yenerel M, Batar B, Küçümen B, Dinç UA, Güven GS, Ulus T, Yüksel A (2011) Glutathione S-transferase M1, GSTT1 and GSTP1 genetic polymorphisms and the risk of age-related macular degeneration. Ophthalmic Res 46:31-37
-
(2011)
Ophthalmic Res
, vol.46
, pp. 31-37
-
-
Güven, M.1
Görgün, E.2
Unal, M.3
Yenerel, M.4
Batar, B.5
Küçümen, B.6
Dinç, U.A.7
Güven, G.S.8
Ulus, T.9
Yüksel, A.10
-
29
-
-
84969148359
-
The genetics basis of pharmatoge-nomics
-
Zdanowicz MM (ed) American Society of Health-System Pharmacists, Bethesda
-
Langaee T, Shin J (2010) The genetics basis of pharmatoge-nomics. In: Zdanowicz MM (ed) Concepts in pharmacogenomics. American Society of Health-System Pharmacists, Bethesda, p 29
-
(2010)
Concepts in Pharmacogenomics
, pp. 29
-
-
Langaee, T.1
Shin, J.2
-
30
-
-
34247134216
-
Age-related macular degeneration in very old individuals with family history
-
DOI 10.1016/j.ajo.2006.11.057, PII S0002939406013754
-
Geirsdottir A, Stefansson E, Jonasson F, Helgadottir G, Sig-urdsson H (2007) Age-related macular degeneration in very old individuals with family history. Am J Ophthalmol 143:889-890 (Pubitemid 46601367)
-
(2007)
American Journal of Ophthalmology
, vol.143
, Issue.5
, pp. 889-890
-
-
Geirsdottir, A.1
Stefansson, E.2
Jonasson, F.3
Helgadottir, G.4
Sigurdsson, H.5
-
32
-
-
0029836759
-
Age-related macular degeneration and smoking: The Rotterdam study
-
Vingerling JR, Hofman A, Grobbee DE, de Jong PT (1996) Age-related macular degeneration and smoking. The Rotterdam study. Arch Ophthalmol 114:1193-1196 (Pubitemid 26338849)
-
(1996)
Archives of Ophthalmology
, vol.114
, Issue.10
, pp. 1193-1196
-
-
Vingerling, J.R.1
Hofman, A.2
Grobbee, D.E.3
De Jong, P.T.V.M.4
-
33
-
-
29744442338
-
Smoking and age related macular degeneration: The number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation
-
DOI 10.1136/bjo.2005.073643
-
Khan JC, Thurlby DA, Shahid H, Clayton DG, Yates JR, Bradley M, Moore AT, Bird AC, Genetic factors in AMD study (2006) Smoking and age related macular degeneration: the number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation. Br J Ophthalmol 90:75-80 (Pubitemid 43029901)
-
(2006)
British Journal of Ophthalmology
, vol.90
, Issue.1
, pp. 75-80
-
-
Khan, J.C.1
Thurlby, D.A.2
Shahid, H.3
Clayton, D.G.4
Yates, J.R.W.5
Bradley, M.6
Moore, A.T.7
Bird, A.C.8
-
34
-
-
34247143301
-
Iron induced oxidative damage as a potential factor in age-related macular degeneration: The Cogan lecture
-
DOI 10.1167/iovs.06-0568
-
Dunaief JL (2006) Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan lecture. Invest Ophthalmol Vis Sci 47:4660-4664 (Pubitemid 46586359)
-
(2006)
Investigative Ophthalmology and Visual Science
, vol.47
, Issue.11
, pp. 4660-4664
-
-
Dunaief, J.L.1
-
35
-
-
0033795036
-
The role of oxidative stress in the pathogenesis of age-related macular degeneration
-
Beatty S, Koh H, Phil M, Henson D, Boulton M (2000) The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 45:115-134
-
(2000)
Surv Ophthalmol
, vol.45
, pp. 115-134
-
-
Beatty, S.1
Koh, H.2
Phil, M.3
Henson, D.4
Boulton, M.5
-
36
-
-
18244383260
-
Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa
-
DOI 10.1002/jcp.20346
-
Shen J, Yang X, Dong A, Petters RM, Peng YW, Wong F, Campochiaro PA (2005) Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa. J Cell Physiol 203:457-464 (Pubitemid 40629006)
-
(2005)
Journal of Cellular Physiology
, vol.203
, Issue.3
, pp. 457-464
-
-
Shen, J.1
Yang, X.2
Dong, A.3
Petters, R.M.4
Peng, Y.-W.5
Wong, F.6
Campochiaro, P.A.7
-
37
-
-
34547963062
-
Oxidative stress modulates complement factor H expression in retinal pigmented epithelial cells by acetylation of FOXO3
-
DOI 10.1074/jbc.M702321200
-
Wu Z, Lauer TW, Sick A, Hackett SF, Campochiaro PA (2007) Oxidative stress modulates complement factor H expression in retinal pigmented epithelial cells by acetylation of FOXO3. J Biol Chem 282:22414-22425 (Pubitemid 47267308)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.31
, pp. 22414-22425
-
-
Wu, Z.1
Lauer, T.W.2
Sick, A.3
Hackett, S.F.4
Campochiaro, P.A.5
-
38
-
-
0034788401
-
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and e and beta carotene for age-related cataract and vision loss: AREDS report no. 9
-
Age-related eye disease study research group (AREDS)
-
Age-related eye disease study research group (AREDS) (2001) A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol 119:1439-1452
-
(2001)
Arch Ophthalmol
, vol.119
, pp. 1439-1452
-
-
-
39
-
-
2442658143
-
Increased expression of iron-regulating genes in monkey and human glaucoma
-
DOI 10.1167/iovs.03-0872
-
Farkas RH, Chowers I, Hackam AS, Kageyama M, Nickells RW, Otteson DC, Duh EJ, Wang C, Valenta DF, Gunatilaka TL, Pease ME, Quigley HA, Zack DJ (2004) Increased expression of iron-regulating genes in monkey and human glaucoma. Invest Oph-thalmol Vis Sci 45:1410-1417 (Pubitemid 38859319)
-
(2004)
Investigative Ophthalmology and Visual Science
, vol.45
, Issue.5
, pp. 1410-1417
-
-
Farkas, R.H.1
Chowers, I.2
Hackam, A.S.3
Kageyama, M.4
Nickells, R.W.5
Otteson, D.C.6
Duh, E.J.7
Wang, C.8
Valenta, D.F.9
Gunatilaka, T.L.10
Pease, M.E.11
Quigley, H.A.12
Zack, D.J.13
-
40
-
-
1842504357
-
The metabolism of neuronal iron and its pathogenic role in neurological disease review
-
DOI 10.1196/annals.1306.002
-
Moos T, Morgan EH (2004) The metabolism of neuronal iron and its pathogenic role in neurological disease: review. Ann N Y Acad Sci 1012:14-26 (Pubitemid 38453512)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1012
, pp. 14-26
-
-
Moos, T.1
Morgan, E.H.2
-
41
-
-
0041560975
-
Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane
-
DOI 10.1001/archopht.121.8.1099
-
Hahn P, Milam AH, Dunaief JL (2003) Maculas affected by age-related macular degeneration contain increased chelatable iron in the retinal pigment epithelium and Bruch's membrane. Arch Ophthalmol 12:1099-1105 (Pubitemid 36962162)
-
(2003)
Archives of Ophthalmology
, vol.121
, Issue.8
, pp. 1099-1105
-
-
Hahn, P.1
Milam, A.H.2
Dunaief, J.L.3
-
42
-
-
4644293303
-
Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration
-
DOI 10.1073/pnas.0405146101
-
Hahn P, Qian Y, Dentchev T, Chen L, Beard J, Harris ZL, Dunaief JL (2004) Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration. Proc Natl Acad Sci USA 10138:13850-13855 (Pubitemid 39298496)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.38
, pp. 13850-13855
-
-
Hahn, P.1
Qian, Y.2
Dentchev, T.3
Chen, L.4
Beard, J.5
Harris, Z.L.6
Dunaief, J.L.7
-
43
-
-
50949102412
-
Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network
-
Muckenthaler MU, Galy B, Hentze MW (2008) Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network. Annu Rev Nutr 28: 197-213
-
(2008)
Annu Rev Nutr
, vol.28
, pp. 197-213
-
-
Muckenthaler, M.U.1
Galy, B.2
Hentze, M.W.3
-
44
-
-
39149112760
-
The functional duality of iron regulatory protein 1
-
Volz K (2008) The functional duality of iron regulatory protein 1. Curr Opin Struct Biol 18:106-111
-
(2008)
Curr Opin Struct Biol
, vol.18
, pp. 106-111
-
-
Volz, K.1
-
45
-
-
68949204940
-
In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation
-
Viatte L, Gröne HJ, Hentze MW, Galy B (2009) In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation. J Mol Med (Berl) 87:913-921
-
(2009)
J Mol Med (Berl)
, vol.87
, pp. 913-921
-
-
Viatte, L.1
Gröne, H.J.2
Hentze, M.W.3
Galy, B.4
-
46
-
-
7044247550
-
Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina
-
Hahn P, Dentchev T, Qian Y, Rouault T, Harris ZL, Dunaief JL (2004) Immunolocalization and regulation of iron handling proteins ferritin and ferroportin in the retina. Mol Vis 10:598-607 (Pubitemid 41358237)
-
(2004)
Molecular Vision
, vol.10
, pp. 598-607
-
-
Hahn, P.1
Dentchev, T.2
Qian, Y.3
Rouault, T.4
Harris, Z.L.5
Dunaief, J.L.6
-
47
-
-
33645307993
-
Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development
-
Smith SR, Ghosh MC, Ollivierre-Wilson H, Hang Tong W, Rouault TA (2006) Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development. Blood Cells Mol Dis 36:283-287
-
(2006)
Blood Cells Mol Dis
, vol.36
, pp. 283-287
-
-
Smith, S.R.1
Ghosh, M.C.2
Ollivierre-Wilson, H.3
Hang Tong, W.4
Rouault, T.A.5
-
48
-
-
37449009448
-
Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum
-
Galy B, Ferring-Appel D, Kaden S, Gröne HJ, Hentze MW (2008) Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum. Cell Metab 7:79-85
-
(2008)
Cell Metab
, vol.7
, pp. 79-85
-
-
Galy, B.1
Ferring-Appel, D.2
Kaden, S.3
Gröne, H.J.4
Hentze, M.W.5
-
49
-
-
0029758487
-
Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress
-
DOI 10.1073/pnas.93.16.8175
-
Hentze MW, Kühn LC (1996) Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress. Proc Natl Acad Sci USA 93:8175-8182 (Pubitemid 26269529)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.16
, pp. 8175-8182
-
-
Hentze, M.W.1
Kuhn, L.C.2
-
50
-
-
33746361251
-
The role of iron regulatory proteins in mammalian iron homeostasis and disease
-
DOI 10.1038/nchembio807, PII NCHEMBIO807
-
Rouault TA (2006) The role of iron regulatory proteins in mammalian iron homeostasis and disease. Nat Chem Biol 2: 406-414 (Pubitemid 44114917)
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.8
, pp. 406-414
-
-
Rouault, T.A.1
-
51
-
-
75649133245
-
Multiple determinants within iron-responsive elements dictate iron regulatory protein binding and regulatory hierarchy
-
Goforth JB, Anderson SA, Nizzi CP, Eisenstein RS (2010) Multiple determinants within iron-responsive elements dictate iron regulatory protein binding and regulatory hierarchy. RNA 16:154-169
-
(2010)
RNA
, vol.16
, pp. 154-169
-
-
Goforth, J.B.1
Anderson, S.A.2
Nizzi, C.P.3
Eisenstein, R.S.4
-
52
-
-
0021289327
-
Deferoxamine (Desferal®)-induced toxic retinal pigmentary degeneration and presumed optic neuropathy
-
Lakhanpal V, Schocket SS, Jiji R (1984) Deferoxamine (desfer-al)-induced toxic retinal pigmentary degeneration and presumed optic neuropathy. Ophthalmology 91:443-451 (Pubitemid 14149071)
-
(1984)
Ophthalmology
, vol.91
, Issue.5
, pp. 443-451
-
-
Lakhanpal, V.1
Schocket, S.S.2
Jiji, R.3
-
53
-
-
0022657047
-
Experimental study of the retinal toxicity of hemoglobinic iron
-
Doly M, Bonhomme B, Vennat JC (1986) Experimental study of the retinal toxicity of hemoglobinic iron. Ophthalmic Res 18: 21-27 (Pubitemid 16170338)
-
(1986)
Ophthalmic Research
, vol.18
, Issue.1
, pp. 21-27
-
-
Doly, M.1
Bonhomme, B.2
Vennat, J.C.3
-
54
-
-
0031935652
-
Iron-induced apoptosis in the photoreceptor cells of rats
-
Wang ZJ, Lam KW, Lam TT, Tso MO (1998) Iron-induced apoptosis in the photoreceptor cells of rats. Invest Ophthalmol Vis Sci 39:631-633 (Pubitemid 28110697)
-
(1998)
Investigative Ophthalmology and Visual Science
, vol.39
, Issue.3
, pp. 631-633
-
-
Wang, Z.-J.1
Lam, K.-W.2
Lam, T.T.3
Tso, M.O.M.4
-
55
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
DOI 10.1126/science.1110359
-
Haines JL, Hauser MA, Schmidt S, Scott WK, Olson LM, Gallins P, Spencer KL, Kwan SY, Noureddine M, Gilbert JR, Schnetz-Boutaud N, Agarwal A, Postel EA, Pericak-Vance MA (2005) Complement factor H variant increases the risk of age-related macular degeneration. Science 308:419-421 (Pubitemid 40530081)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 419-421
-
-
Haines, J.L.1
Hauser, M.A.2
Schmidt, S.3
Scott, W.K.4
Olson, L.M.5
Gallins, P.6
Spencer, K.L.7
Shu, Y.K.8
Noureddine, M.9
Gilbert, J.R.10
Schnetz-Boutaud, N.11
Agarwal, A.12
Postel, E.A.13
Pericak-Vance, M.A.14
-
56
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
DOI 10.1126/science.1109557
-
Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308:385-389 (Pubitemid 40530070)
-
(2005)
Science
, vol.308
, Issue.5720
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.-Y.4
Sackler, R.S.5
Haynes, C.6
Henning, A.K.7
SanGiovanni, J.P.8
Mane, S.M.9
Mayne, S.T.10
Bracken, M.B.11
Ferris, F.L.12
Ott, J.13
Barnstable, C.14
Hoh, J.15
-
57
-
-
36049042661
-
A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration
-
DOI 10.1073/pnas.0703933104
-
Kanda A, Chen W, Othman M, Branham KE, Brooks M, Khanna R, He S, Lyons R, Abecasis GR, Swaroop A (2007) A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. Proc Natl Acad Sci USA 104:16227-16232 (Pubitemid 350099389)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.41
, pp. 16227-16232
-
-
Kanda, A.1
Chen, W.2
Othman, M.3
Branham, K.E.H.4
Brooks, M.5
Khanna, R.6
He, S.7
Lyons, R.8
Abecasis, G.R.9
Swaroop, A.10
-
58
-
-
37549048032
-
Review of genetics in age related macular degeneration
-
Montezuma SR, Sobrin L, Seddon JM (2007) Review of genetics in age related macular degeneration. Semin Ophthalmol 22:229-240
-
(2007)
Semin Ophthalmol
, vol.22
, pp. 229-240
-
-
Montezuma, S.R.1
Sobrin, L.2
Seddon, J.M.3
-
59
-
-
46249098503
-
Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA
-
DOI 10.1038/ng.170, PII NG170
-
Fritsche LG, Loenhardt T, Janssen A, Fisher SA, Rivera A, Keilhauer CN, Weber BH (2008) Age-related macular degeneration is associated with an unstable ARMS2 (LOC387715) mRNA. Nat Genet 40:892-896 (Pubitemid 351913654)
-
(2008)
Nature Genetics
, vol.40
, Issue.7
, pp. 892-896
-
-
Fritsche, L.G.1
Loenhardt, T.2
Janssen, A.3
Fisher, S.A.4
Rivera, A.5
Keilhauer, C.N.6
Weber, B.H.F.7
-
60
-
-
45449085894
-
Age-related macular degeneration: A perspective on genetic studies
-
DOI 10.1038/sj.eye.6702844, PII 6702844
-
Patel N, Adewoyin T, Chong NV (2008) Age-related macular degeneration: a perspective on genetic studies. Eye 22(6):768-776 (Pubitemid 351850512)
-
(2008)
Eye
, vol.22
, Issue.6
, pp. 768-776
-
-
Patel, N.1
Adewoyin, T.2
Chong, N.V.3
-
61
-
-
59849104241
-
Molecular pathology of age-related macular degeneration
-
Ding X, Patel M, Chan CC (2009) Molecular pathology of age-related macular degeneration. Prog Retin Eye Res 28:1-18
-
(2009)
Prog Retin Eye Res
, vol.28
, pp. 1-18
-
-
Ding, X.1
Patel, M.2
Chan, C.C.3
-
62
-
-
2042546096
-
Balancing acts: Molecular control of mammalian iron metabolism
-
DOI 10.1016/S0092-8674(04)00343-5, PII S0092867404003435
-
Hentze MW, Muckenthaler MU, Andrews NC (2004) Balancing acts: molecular control of mammalian iron metabolism. Cell 117:285-297 (Pubitemid 38534536)
-
(2004)
Cell
, vol.117
, Issue.3
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
63
-
-
34547782810
-
Copper and iron disorders of the brain
-
DOI 10.1146/annurev.neuro.30.051606.094232
-
Madsen E, Gitlin JD (2007) Copper and iron disorders of the brain. Annu Rev Neurosci 30:317-337 (Pubitemid 47224759)
-
(2007)
Annual Review of Neuroscience
, vol.30
, pp. 317-337
-
-
Madsen, E.1
Gitlin, J.D.2
|