Increased TGF-β1-mediated suppression of growth and motility in castrate-resistant prostate cancer cells is consistent with Smad2/3 signaling

Prostate

Volumn 72, Issue 12, 2012, Pages 1339-1350

  Miles, Fayth L ^a   Tung, Navpreet S ^b   Aguiar, Adam A ^a   Kurtoglu, Senem ^a   Sikes, Robert A ^a  

^a UNIVERSITY OF DELAWARE   (United States)

^b DELAWARE STATE UNIVERSITY   (United States)

Author keywords

androgen sensitive; castrate resistant; cell cycle regulation; growth; invasion; motility; prostate cancer; TGF 1

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; CYCLIN D; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 2B; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CANCER CELL; CANCER INHIBITION; CANCER INVASION; CASTRATION RESISTANT PROSTATE CANCER; CELL CYCLE; CELL INVASION; CELL MOTILITY; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA CONTENT; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; GROWTH INHIBITORS; HUMANS; MALE; ORCHIECTOMY; PHOSPHORYLATION; PROSTATIC NEOPLASMS; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84864286794     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.22482     Document Type: Article

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