Estimating intrinsic structural preferences of de novo emerging random-sequence proteins: Is aggregation the main bottleneck?

FEBS Letters

Volumn 586, Issue 16, 2012, Pages 2468-2472

  Ángyán, Annamária F ^a   Perczel, András ^a,b   Gáspári, Zoltán ^c  

^a EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c PÁZMÁNY PÉTER CATHOLIC UNIVERSITY   (Hungary)

Author keywords

Aggregation propensity; De novo protein; Protein evolution; Random sequence; Structure prediction

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; COMPUTER MODEL; COMPUTER PREDICTION; DNA BASE COMPOSITION; DNA SEQUENCE; GENETIC DATABASE; GENOMICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; QUALITY CONTROL; STRUCTURE ANALYSIS;

ANIMALS; BASE COMPOSITION; EVOLUTION, MOLECULAR; GENOME, HUMAN; HUMANS; MICE; NUCLEOTIDES; OPEN READING FRAMES; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; PROTEINS; PROTEOMICS; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA;

EID: 84864285455     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.06.007     Document Type: Article

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