메뉴 건너뛰기




Volumn 174, Issue 3, 2012, Pages 177-185

RNA-Mediated Gene Silencing in Candida albicans: Inhibition of Hyphae Formation by Use of RNAi Technology

Author keywords

Candida albicans; EFG1 gene; Pathogenesis; RNAi

Indexed keywords

ANTIFUNGAL AGENT; BIOLOGICAL PRODUCT; DNA BINDING PROTEIN; EFG1 PROTEIN, CANDIDA ALBICANS; FUNGAL PROTEIN; FUNGAL RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

EID: 84864281651     PISSN: 0301486X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11046-012-9539-6     Document Type: Article
Times cited : (17)

References (33)
  • 1
    • 0036348629 scopus 로고    scopus 로고
    • Fungal morphogenesis and host invasion
    • Gow NA, Brown AJ, Odds FC. Fungal morphogenesis and host invasion. Curr Opin Microbiol. 2002; 5(4): 366-71.
    • (2002) Curr Opin Microbiol , vol.5 , Issue.4 , pp. 366-371
    • Gow, N.A.1    Brown, A.J.2    Odds, F.C.3
  • 2
    • 0036202213 scopus 로고    scopus 로고
    • Linking fungal morphogenesis with virulence
    • Rooney PJ, Klein BS. Linking fungal morphogenesis with virulence. Cell Microbiol. 2002; 4(3): 127-37.
    • (2002) Cell Microbiol , vol.4 , Issue.3 , pp. 127-137
    • Rooney, P.J.1    Klein, B.S.2
  • 4
    • 0034115442 scopus 로고    scopus 로고
    • Role of hyphal formation in interactions of Candida albicans with endothelial cells
    • Phan QT, Belanger PH, Filler SG. Role of hyphal formation in interactions of Candida albicans with endothelial cells. Infect Immun. 2000; 68(6): 3485-90.
    • (2000) Infect Immun , vol.68 , Issue.6 , pp. 3485-3490
    • Phan, Q.T.1    Belanger, P.H.2    Filler, S.G.3
  • 5
    • 0034053028 scopus 로고    scopus 로고
    • EFG1 null mutants of Candida albicans switch but cannot express the complete phenotype of white-phase budding cells
    • Srikantha T, Tsai LK, Daniels K, Soll DR. EFG1 null mutants of Candida albicans switch but cannot express the complete phenotype of white-phase budding cells. J Bacteriol. 2000; 182(6): 1580-91.
    • (2000) J Bacteriol , vol.182 , Issue.6 , pp. 1580-1591
    • Srikantha, T.1    Tsai, L.K.2    Daniels, K.3    Soll, D.R.4
  • 6
    • 0036081594 scopus 로고    scopus 로고
    • Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs
    • Felk A, Kretschmar M, Albrecht A, Schaller M, Beinhauer S, Nichterlein T, et al. Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs. Infect Immun. 2002; 70(7): 3689-700.
    • (2002) Infect Immun , vol.70 , Issue.7 , pp. 3689-3700
    • Felk, A.1    Kretschmar, M.2    Albrecht, A.3    Schaller, M.4    Beinhauer, S.5    Nichterlein, T.6
  • 7
    • 0033870274 scopus 로고    scopus 로고
    • Transcription factors in Candida albicans-environmental control of morphogenesis
    • Ernst JF. Transcription factors in Candida albicans-environmental control of morphogenesis. Microbiology. 2000; 146(8): 1763.
    • (2000) Microbiology , vol.146 , Issue.8 , pp. 1763
    • Ernst, J.F.1
  • 8
    • 0032775156 scopus 로고    scopus 로고
    • Regulatory networks controlling Candida albicans morphogenesis
    • Brown AJP, Gow NAR. Regulatory networks controlling Candida albicans morphogenesis. Trends Microbiol. 1999; 7(8): 333-8.
    • (1999) Trends Microbiol , vol.7 , Issue.8 , pp. 333-338
    • Brown, A.J.P.1    Gow, N.A.R.2
  • 9
    • 0030945488 scopus 로고    scopus 로고
    • Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi
    • Stoldt VR, Sonneborn A, Leuker CE, Ernst JF. Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi. EMBO J. 1997; 16(8): 1982-91.
    • (1997) EMBO J , vol.16 , Issue.8 , pp. 1982-1991
    • Stoldt, V.R.1    Sonneborn, A.2    Leuker, C.E.3    Ernst, J.F.4
  • 11
    • 47049118329 scopus 로고    scopus 로고
    • Functional mapping of the Candida albicans Efg1 regulator
    • Noffz CS, Liedschulte V, Lengeler K, Ernst JF. Functional mapping of the Candida albicans Efg1 regulator. Eukaryot Cell. 2008; 7(5): 881-93.
    • (2008) Eukaryot Cell , vol.7 , Issue.5 , pp. 881-893
    • Noffz, C.S.1    Liedschulte, V.2    Lengeler, K.3    Ernst, J.F.4
  • 12
    • 27244436568 scopus 로고    scopus 로고
    • Contributions of hyphae and hypha-co-regulated genes to Candida albicans virulence
    • Kumamoto CA, Vinces MD. Contributions of hyphae and hypha-co-regulated genes to Candida albicans virulence. Cell Microbiol. 2005; 7(11): 1546-54.
    • (2005) Cell Microbiol , vol.7 , Issue.11 , pp. 1546-1554
    • Kumamoto, C.A.1    Vinces, M.D.2
  • 13
    • 0344199896 scopus 로고    scopus 로고
    • Chlamydospore formation in Candida albicans requires the Efg1p morphogenetic regulator
    • Sonneborn A, Bockmuhl DP, Ernst JF. Chlamydospore formation in Candida albicans requires the Efg1p morphogenetic regulator. Infect Immun. 1999; 67(10): 5514-7.
    • (1999) Infect Immun , vol.67 , Issue.10 , pp. 5514-5517
    • Sonneborn, A.1    Bockmuhl, D.P.2    Ernst, J.F.3
  • 14
    • 0036156250 scopus 로고    scopus 로고
    • Transcriptional regulators Cph1p and Efg1p mediate activation of the Candida albicans virulence gene SAP5 during infection
    • Staib P, Kretschmar M, Nichterlein T, Hof H, Morschhauser J. Transcriptional regulators Cph1p and Efg1p mediate activation of the Candida albicans virulence gene SAP5 during infection. Infect Immun. 2002; 70(2): 921-7.
    • (2002) Infect Immun , vol.70 , Issue.2 , pp. 921-927
    • Staib, P.1    Kretschmar, M.2    Nichterlein, T.3    Hof, H.4    Morschhauser, J.5
  • 15
    • 0042028356 scopus 로고    scopus 로고
    • Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efg1 mutant is associated with attenuated virulence during infection of oral epithelium
    • Korting HC, Hube B, Oberbauer S, Januschke E, Hamm G, Albrecht A, et al. Reduced expression of the hyphal-independent Candida albicans proteinase genes SAP1 and SAP3 in the efg1 mutant is associated with attenuated virulence during infection of oral epithelium. J Med Microbiol. 2003; 52(Pt 8): 623-32.
    • (2003) J Med Microbiol , vol.52 , Issue.Pt 8 , pp. 623-632
    • Korting, H.C.1    Hube, B.2    Oberbauer, S.3    Januschke, E.4    Hamm, G.5    Albrecht, A.6
  • 16
    • 0031819787 scopus 로고    scopus 로고
    • Candida albicans ALS3 and insights into the nature of the ALS gene family
    • Hoyer LL, Payne TL, Bell M, Myers AM, Scherer S. Candida albicans ALS3 and insights into the nature of the ALS gene family. Curr Genet. 1998; 33(6): 451-9.
    • (1998) Curr Genet , vol.33 , Issue.6 , pp. 451-459
    • Hoyer, L.L.1    Payne, T.L.2    Bell, M.3    Myers, A.M.4    Scherer, S.5
  • 17
    • 0032880015 scopus 로고    scopus 로고
    • HWP1 functions in the morphological development of Candida albicans downstream of EFG1, TUP1, and RBF1
    • Sharkey LL, McNemar MD, Saporito-Irwin SM, Sypherd PS, Fonzi WA. HWP1 functions in the morphological development of Candida albicans downstream of EFG1, TUP1, and RBF1. J Bacteriol. 1999; 181(17): 5273-9.
    • (1999) J Bacteriol , vol.181 , Issue.17 , pp. 5273-5279
    • Sharkey, L.L.1    McNemar, M.D.2    Saporito-Irwin, S.M.3    Sypherd, P.S.4    Fonzi, W.A.5
  • 18
    • 0036224725 scopus 로고    scopus 로고
    • Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway
    • Fu Y, Ibrahim AS, Sheppard DC, Chen YC, French SW, Cutler JE, et al. Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway. Mol Microbiol. 2002; 44(1): 61-72.
    • (2002) Mol Microbiol , vol.44 , Issue.1 , pp. 61-72
    • Fu, Y.1    Ibrahim, A.S.2    Sheppard, D.C.3    Chen, Y.C.4    French, S.W.5    Cutler, J.E.6
  • 19
    • 26944471385 scopus 로고    scopus 로고
    • RNA silencing in fungi: mechanisms and applications
    • Nakayashiki H. RNA silencing in fungi: mechanisms and applications. FEBS Lett. 2005; 579(26): 5950-7.
    • (2005) FEBS Lett , vol.579 , Issue.26 , pp. 5950-5957
    • Nakayashiki, H.1
  • 21
    • 70349665214 scopus 로고    scopus 로고
    • Life without RNAi: noncoding RNAs and their functions in Saccharomyces cerevisiae
    • Harrison BR, Yazgan O, Krebs JE. Life without RNAi: noncoding RNAs and their functions in Saccharomyces cerevisiae. Biochem Cell Biol. 2009; 87(5): 767-79.
    • (2009) Biochem Cell Biol , vol.87 , Issue.5 , pp. 767-779
    • Harrison, B.R.1    Yazgan, O.2    Krebs, J.E.3
  • 23
    • 58749113430 scopus 로고    scopus 로고
    • A three-dimensional view of the molecular machinery of RNA interference
    • Jinek M, Doudna JA. A three-dimensional view of the molecular machinery of RNA interference. Nature. 2009; 457(7228): 405-12.
    • (2009) Nature , vol.457 , Issue.7228 , pp. 405-412
    • Jinek, M.1    Doudna, J.A.2
  • 24
    • 0026441194 scopus 로고
    • Quelling: transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences
    • Romano N, Macino G. Quelling: transient inactivation of gene expression in Neurospora crassa by transformation with homologous sequences. Mol Microbiol. 1992; 6(22): 3343-53.
    • (1992) Mol Microbiol , vol.6 , Issue.22 , pp. 3343-3353
    • Romano, N.1    Macino, G.2
  • 25
    • 3142621221 scopus 로고    scopus 로고
    • RNA interference in Histoplasma capsulatum demonstrates a role for alpha-(1,3)-glucan in virulence
    • Rappleye CA, Engle JT, Goldman WE. RNA interference in Histoplasma capsulatum demonstrates a role for alpha-(1, 3)-glucan in virulence. Mol Microbiol. 2004; 53(1): 153-65.
    • (2004) Mol Microbiol , vol.53 , Issue.1 , pp. 153-165
    • Rappleye, C.A.1    Engle, J.T.2    Goldman, W.E.3
  • 26
    • 56949099196 scopus 로고    scopus 로고
    • RNA interference: roles in fungal biology
    • Nakayashiki H, Nguyen QB. RNA interference: roles in fungal biology. Curr Opin Microbiol. 2008; 11(6): 494-502.
    • (2008) Curr Opin Microbiol , vol.11 , Issue.6 , pp. 494-502
    • Nakayashiki, H.1    Nguyen, Q.B.2
  • 27
    • 24144437391 scopus 로고    scopus 로고
    • Efficient RNAi-based gene family knockdown via set cover optimization
    • Zhao W, Fanning ML, Lane T. Efficient RNAi-based gene family knockdown via set cover optimization. Artif Intell Med. 2005; 35(1-2): 61-73.
    • (2005) Artif Intell Med , vol.35 , Issue.1-2 , pp. 61-73
    • Zhao, W.1    Fanning, M.L.2    Lane, T.3
  • 28
    • 0036188983 scopus 로고    scopus 로고
    • RNA interference in the pathogenic fungus Cryptococcus neoformans
    • Liu H, Cottrell TR, Pierini LM, Goldman WE, Doering TL. RNA interference in the pathogenic fungus Cryptococcus neoformans. Genetics. 2002; 160(2): 463-70.
    • (2002) Genetics , vol.160 , Issue.2 , pp. 463-470
    • Liu, H.1    Cottrell, T.R.2    Pierini, L.M.3    Goldman, W.E.4    Doering, T.L.5
  • 29
    • 0037452674 scopus 로고    scopus 로고
    • Uptake and antifungal activity of oligonucleotides in Candida albicans
    • Disney MD, Haidaris CG, Turner DH. Uptake and antifungal activity of oligonucleotides in Candida albicans. Proc Natl Acad Sci USA. 2003; 100(4): 1530-4.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.4 , pp. 1530-1534
    • Disney, M.D.1    Haidaris, C.G.2    Turner, D.H.3
  • 30
    • 78349309117 scopus 로고    scopus 로고
    • Characterizing the role of RNA silencing components in Cryptococcus neoformans
    • Janbon G, Maeng S, Yang DH, Ko YJ, Jung KW, Moyrand F, et al. Characterizing the role of RNA silencing components in Cryptococcus neoformans. Fungal Genet Biol. 2010; 47(12): 1070-80.
    • (2010) Fungal Genet Biol , vol.47 , Issue.12 , pp. 1070-1080
    • Janbon, G.1    Maeng, S.2    Yang, D.H.3    Ko, Y.J.4    Jung, K.W.5    Moyrand, F.6
  • 31
    • 34248213643 scopus 로고    scopus 로고
    • Targeting polyamines of Aspergillus nidulans by siRNA specific to fungal ornithine decarboxylase gene
    • Khatri M, Rajam MV. Targeting polyamines of Aspergillus nidulans by siRNA specific to fungal ornithine decarboxylase gene. Med Mycol. 2007; 45(3): 211-20.
    • (2007) Med Mycol , vol.45 , Issue.3 , pp. 211-220
    • Khatri, M.1    Rajam, M.V.2
  • 32
    • 78650435515 scopus 로고    scopus 로고
    • Hairpin dsRNA does not trigger RNA interference in Candida albicans cells
    • Staab JF, White TC, Marr KA. Hairpin dsRNA does not trigger RNA interference in Candida albicans cells. Yeast. 2011; 28(1): 1-8.
    • (2011) Yeast , vol.28 , Issue.1 , pp. 1-8
    • Staab, J.F.1    White, T.C.2    Marr, K.A.3
  • 33
    • 0035103447 scopus 로고    scopus 로고
    • An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans
    • De Backer MD, Nelissen B, Logghe M, Viaene J, Loonen I, Vandoninck S, et al. An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans. Nat Biotechnol. 2001; 19(3): 235-41.
    • (2001) Nat Biotechnol , vol.19 , Issue.3 , pp. 235-241
    • de Backer, M.D.1    Nelissen, B.2    Logghe, M.3    Viaene, J.4    Loonen, I.5    Vandoninck, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.