Role of hyphal formation in interactions of Candida albicans with endothelial cells

Infection and Immunity

Volumn 68, Issue 6, 2000, Pages 3485-3490

  Phan, Quynh T ^a   Belanger, Paul H ^a   Filler, Scott G ^a,b,c  

^a St John's Cardiovascular Research Center   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1;

ARTICLE; CANDIDA ALBICANS; CELL DAMAGE; CELL INTERACTION; CELL TRANSFORMATION; ENDOCYTOSIS; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VIRULENCE;

CANDIDA ALBICANS; DNA-BINDING PROTEINS; E-SELECTIN; ENDOCYTOSIS; ENDOTHELIUM, VASCULAR; FUNGAL PROTEINS; GENES, FUNGAL; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MORPHOGENESIS; MUTATION; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS;

EID: 0034115442     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.6.3485-3490.2000     Document Type: Article

References (31)

1. Braun, B. R., and A. D. Johnson. 1997. Control of filament formation in Candida albicans by the transcriptional repressor TUP1. Science 277:105-109.
2. Brown, A. J., and N. A. Gow. 1999. Regulatory networks controlling Candida albicans morphogenesis. Trends Microbiol. 7:333-338.
3. Csank, C., K. Schroppel, E. Leberer, D. Harcus, O. Mohamed, S. Meloche, D. Y. Thomas, and M. Whiteway. 1998. Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis. Infect. Immun. 66:2713-2721.
4. Deslauriers, N., J. Michaud, B. Carre, and C. Leveillee. 1996. Dynamic expression of cell-surface antigens probed with Candida albicans-specific monoclonal antibodies. Microbiology 142:1239-1248.
5. Edmond, M. B., S. E. Wallace, D. K. McClish, M. A. Pfaller, R. N. Jones, and R. P. Wenzel. 1999. Nosocomial bloodstream infections in United States hospitals: a three-year analysis. Clin. Infect. Dis. 29:239-244.
6. Edwards, J. E., Jr. 1995. Candida species, p. 2289-2306. In G. L. Mandell, J. E. Bennett, and R. Dolin (ed.), Mandell, Douglas and Bennett's principals and practice of infectious diseases, 4th ed. Churchill Livingston, New York, N.Y.
7. Filler, S. G., B. O. Ibe, A. S. Ibrahim, M. A. Ghannoum, J. U. Raj, and J. E. Edwards, Jr. 1994. Mechanisms by which Candida albicans induces endothelial cell prostaglandin synthesis. Infect. Immun. 62:1064-1069.
8. Filler, S. G., B. O. Ibe, P. M. Luckett, J. U. Raj, and J. E. Edwards, Jr. 1991. Candida albicans stimulates endothelial cell eicosanoid production. J. Infect. Dis. 164:928-935.
9. Filler, S. G., A. S. Pfunder, B. J. Spellberg, J. P. Spellberg, and J. E. Edwards, Jr. 1996. Candida albicans stimulates cytokine production and leukocyte adhesion molecule expression by endothelial cells. Infect. Immun. 64:2609-2617.
10. Filler, S. G., J. N. Swerdloff, C. Hobbs, and P. M. Luckett. 1995. Penetration and damage of endothelial cells by Candida albicans. Infect. Immun. 63:976-983.
11. Fonzi, W. A., and M. Y. Irwin. 1993. Isogenic strain construction and gene mapping in Candida albicans. Genetics 134:717-728.
12. Fratti, R. A., P. H. Belanger, M. A. Ghannoum, J. E. Edwards, Jr., and S. G. Filler. 1998. Endothelial cell injury caused by Candida albicans is dependent on iron. Infect. Immun. 66:191-196.
13. Fratti, R. A., M. A. Ghannoum, J. E. Edwards, Jr., and S. G. Filler. 1996. Gamma interferon protects endothelial cells from damage by Candida albicans by inhibiting endothelial cell phagocytosis. Infect. Immun. 64:4714-4718.
14. Hoover, C. I., M. J. Jantapour, G. Newport, N. Agabian, and S. J. Fisher. 1998. Cloning and regulated expression of the Candida albicans phospholipase B (PLB1) gene. FEMS Microbiol. Lett. 167:163-169.
15. Ibrahim, A. S., S. G. Filler, D. Sanglard, J. E. Edwards, Jr., and B. Hube. 1998. Secreted aspartyl proteinases and interactions of Candida albicans with human endothelial cells. Infect. Immun. 66:3003-3005.
16. Jaffe, E. A., R. L. Nachman, C. G. Becker, and C. R. Minick. 1973. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Investig. 52:2745-2756.
17. Kapteyn, J. C., P. Van Egmond, E. Sievi, H. Van Den Ende, M. Makarow, and F. M. Klis. 1999. The contribution of the O-glycosylated protein Pir2p/ Hsp150 to the construction of the yeast cell wall in wild-type cells and beta 1,6-glucan-deficient mutants. Mol. Microbiol. 31:1835-1844.
18. Kohler, J. R., and G. R. Fink. 1996. Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development. Proc. Natl. Acad. Sci. USA 93:13223-13228.
19. Leberer, E., D. Harcus, I. D. Broadbent, K. L. Clark, D. Dignard, K. Ziegelbauer, A. Schmidt, N. A. Gow, A. J. Brown, and D. Y. Thomas. 1996. Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans. Proc. Natl. Acad. Sci. USA 93:13217-13222.
20. Leberer, E., K. Ziegelbauer, A. Schmidt, D. Harcus, D. Dignard, J. Ash, L. Johnson, and D. Y. Thomas. 1997. Virulence and hyphal formation of Candida albicans require the Ste20p-like protein kinase CaCla4p. Curr. Biol. 7:539-546.
21. Leidich, S. D., A. S. Ibrahim, Y. Fu, A. Koul, C. Jessup, J. Vitullo, W. Fonzi, F. Mirbod, S. Nakashima, Y. Nozawa, and M. A. Ghannoum. 1998. Cloning and disruption of caPLB1, a phospholipase B gene involved in the pathogenicity of Candida albicans. J. Biol. Chem. 273:26078-26086.
22. Levitz, S. M., D. J. DiBenedetto, and R. D. Diamond. 1987. A rapid fluorescent assay to distinguish attached from phagocytized yeast particles. J. Immunol. Methods 101:37-42.
23. Liu, H., J. Kohler, and G. R. Fink. 1994. Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog. Science 266:1723-1726.
24. Lo, H. J., J. R. Kohler, B. DiDomenico, D. Loebenberg, A. Cacciapuoti, and G. R. Fink. 1997. Nonfilamentous C. albicans mutants are avirulent. Cell 90: 939-949.
25. Noel, R. F., Jr., T. T. Sato, C. Mendez, M. C. Johnson, and T. H. Pohlman. 1995. Activation of human endothelial cells by viable or heat-killed gram-negative bacteria requires soluble CD14. Infect. Immun. 63:4046-4053.
26. Orozco, A. S., X. Zhou, and S. G. Filler. 2000. Mechanisms of the proinflammatory response of endothelial cells to Candida albicans infection. Infect. Immun. 68:1134-1141.
27. Russo, P., N. Kalkkinen, H. Sareneva, J. Paakkola, and M. Makarow. 1992. A heat shock gene from Saccharomyces cerevisiae encoding a secretory glycoprotein. Proc. Natl. Acad. Sci. USA 89:3671-3675.
28. Schena, M., D. Shalon, R. W. Davis, and P. O. Brown. 1995. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270:467-470.
29. Schena, M., D. Shalon, R. Heller, A. Chai, P. O. Brown, and R. W. Davis. 1996. Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. Proc. Natl. Acad. Sci. USA 93:10614-10619.
30. Stoldt, V. R., A. Sonneborn, C. E. Leuker, and J. F. Ernst. 1997. Efg1p, an essential regulator of morphogenesis of the human pathogen Candida albicans, is a member of a conserved class of bHLH proteins regulating morphogenetic processes in fungi. EMBO J. 16:1982-1991.
31. Torosantucci, A., M. J. Gomez, C. Bromuro, I. Casalinuovo, and A. Cassone. 1991. Biochemical and antigenic characterization of mannoprotein constituents released from yeast and mycelial forms of Candida albicans. J. Med. Vet. Mycol. 29:361-372.