Lipid-soluble extracts from Salvi miltiorrhiz inhibit production of LPS-induced inflammatory mediators vi NF-κB modulation in RAW 264.7 cells and perform antiinflammatory effects in vivo

Phytotherapy Research

Volumn 26, Issue 8, 2012, Pages 1195-1204

  Li, Meng ^a,b   Zhang, Lei ^c   Cai, Run Lan ^a   Gao, Yuan ^a   Qi, Yun ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c CENTER FOR DRUG EVALUATION   (China)

Author keywords

antiinflammatory effect; inflammatory mediators; NF B; RAW 264.7 cells; Salvi miltiorrhiza

Indexed keywords

15,16 DIHYDROTANSHINONE I; CD14 ANTIGEN; CRYPTOTANSHINONE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PLANT MEDICINAL PRODUCT; REACTIVE OXYGEN METABOLITE; SALVIA MILTIORRHIZA EXTRACT; SALVIA MILTIORRHIZA LIPID SOLUBLE EXTRACT; TANSHINONE; TANSHINONE I; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL LINE; CELL NUCLEUS; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; DOSE RESPONSE; DRUG DOSE COMPARISON; EAR EDEMA; ENDOTOXEMIA; ENZYME INHIBITION; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SEPSIS; SURVIVAL RATE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD14; CELL LINE, TUMOR; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DRUGS, CHINESE HERBAL; ENDOTOXEMIA; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPIDS; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED ICR; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PHYTOTHERAPY; REACTIVE OXYGEN SPECIES; SALVIA MILTIORRHIZA; SEPSIS; SOLUBILITY; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; MUS;

EID: 84864268543     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3680     Document Type: Article

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