Optimal experiment selection for parameter estimation in biological differential equation models

BMC Bioinformatics

Volumn 13, Issue 1, 2012, Pages

  Transtrum, Mark K ^a   Qiu, Peng ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Data fitting; Differential equation models; Experimental design; Parameter estimation; Systems biology

Indexed keywords

ADDITIONAL DATUM; BEST FIT; BIOLOGICAL MODELS; DATA FITTINGS; DECAY RATE; DIFFERENTIAL EQUATION MODEL; EXPERIMENT DATA; FISHER INFORMATION; GENE REGULATORY NETWORKS; HILL COEFFICIENT; LOCAL MINIMUMS; MICHAELIS-MENTEN CONSTANT; MINIMIZATION PROBLEMS; MODEL CALIBRATION; MODEL PREDICTION; OPTIMAL EXPERIMENTS; PARAMETER VALUES; PREDICTING MODELS; SYSTEMS BIOLOGY;

DECAY (ORGANIC); DESIGN OF EXPERIMENTS; DIFFERENTIAL EQUATIONS; EXPERIMENTS; FISHER INFORMATION MATRIX; GENES; REACTION RATES;

PARAMETER ESTIMATION;

ALGORITHM; ARTICLE; BIOLOGICAL MODEL; GENE REGULATORY NETWORK; MATHEMATICAL COMPUTING; METHODOLOGY; STATISTICS;

ALGORITHMS; GENE REGULATORY NETWORKS; MATHEMATICAL COMPUTING; MODELS, GENETIC; RESEARCH DESIGN;

MLCS; MLOWN;

EID: 84864259005     PISSN: None     EISSN: 14712105     Source Type: Journal    
DOI: 10.1186/1471-2105-13-181     Document Type: Article

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