메뉴 건너뛰기




Volumn 31, Issue 5, 2012, Pages 473-482

Piperine as an adjuvant increases the efficacy of curcumin in mitigating benzo(a)pyrene toxicity

Author keywords

antioxidant; benzo(a)pyrene; curcumin; oxidative stress; piperine; reactive oxygen species

Indexed keywords

BENZO[A]PYRENE; CARBONYL DERIVATIVE; CATALASE; CURCUMIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; PIPERINE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 84864253544     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327111421943     Document Type: Article
Times cited : (41)

References (57)
  • 3
    • 0034729280 scopus 로고    scopus 로고
    • Potentiation of benzo[a]pyrene-induced pulmonary and forestomach tumorigenesis in mice by D,L-buthionine-S,R-sulfoximine-mediated tissue glutathione depletion
    • DOI 10.1016/S0304-3835(00)00333-5, PII S0304383500003335
    • Srivastava SK, Xia H, Pal A, Hu X, Guo J, Singh SV. Potentiation of benzo[a]pyrene-induced pulmonary and forestomach tumorigenesis in mice by D,L-buthionine-S,R-sulfoximine-mediated tissue glutathione depletion. Cancer Lett. 2000 ; 153: 35-39 (Pubitemid 30209840)
    • (2000) Cancer Letters , vol.153 , Issue.1-2 , pp. 35-39
    • Srivastava, S.K.1    Xia, H.2    Pal, A.3    Hu, X.4    Guo, J.5    Singh, S.V.6
  • 4
    • 0025893062 scopus 로고
    • Benzo-a-pyrene: Environmental partitioning and human exposure
    • Hattemer-Frey HA, Travis CC. Benzo-a-pyrene: environmental partitioning and human exposure. Toxicol Ind Health. 1991 ; 7: 141-157
    • (1991) Toxicol Ind Health , vol.7 , pp. 141-157
    • Hattemer-Frey, H.A.1    Travis, C.C.2
  • 5
    • 0342327333 scopus 로고    scopus 로고
    • The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics
    • Seidegard J, Ekstro G. The role of human glutathione transferases and epoxide hydrolases in the metabolism of xenobiotics. Environ Health Perspect. 1997 ; 105: 791-799 (Pubitemid 27372964)
    • (1997) Environmental Health Perspectives , vol.105 , Issue.SUPPL. 4 , pp. 791-799
    • Seidegard, J.1    Ekstrom, G.2
  • 6
    • 0038678902 scopus 로고    scopus 로고
    • Benzo[a]pyrene diones are produced by photochemical and enzymatic oxidation and induce concentration-dependent decreases in the proliferative state of human pulmonary epithelial cells
    • DOI 10.1080/15287390306409
    • Reed M, Monske M, Lauer F, Meserole S, Born J, Burchiel S. Benzo[a]pyrene diones are produced by photochemical and enzymatic oxidation and induce concentration-dependent decreases in the proliferative state of human pulmonary epithelial cells. J Toxicol Environ Health A. 2003 ; 66: 1189-1205 (Pubitemid 36918525)
    • (2003) Journal of Toxicology and Environmental Health - Part A , vol.66 , Issue.13 , pp. 1189-1205
    • Reed, M.D.1    Monske, M.L.2    Lauer, F.T.3    Meserole, S.P.4    Born, J.L.5    Burchiel, S.W.6
  • 7
    • 0342981512 scopus 로고    scopus 로고
    • DNA strand scission by polycyclic aromatic hydrocarbon o-quinones: Role of reactive oxygen species, Cu(II)/Cu(I) redox cycling, and o-Semiquinone Anion radicals
    • DOI 10.1021/bi970367p
    • Flowers L, Ohnishi ST, Penning TM. DNA strand scission by polycyclic aromatic hydrocarbon o-quinones: role of reactive oxygen species, Cu(II)/Cu(I) redox cycling, and o-semiquinone anion radicals. Biochemistry. 1997 ; 36: 8640-8648 (Pubitemid 27305149)
    • (1997) Biochemistry , vol.36 , Issue.28 , pp. 8640-8648
    • Flowers, L.1    Ohnishi, T.2    Penning, T.M.3
  • 8
    • 0019829342 scopus 로고
    • Mechanisms of chemical carcinogenesis
    • Miller EC, Miller JA. Mechanisms of chemical carcinogenesis. Cancer. 1981 ; 47: 1055-1064 (Pubitemid 11159574)
    • (1981) Cancer , vol.47 , Issue.SUPPL. 5 , pp. 1055-1064
    • Miller, E.C.1    Miller, J.A.2
  • 9
    • 0021964203 scopus 로고
    • Prooxidant states and tumor promotion
    • Cerutti PA. Prooxidant states and tumor promotion. Science. 1985 ; 227: 375-381 (Pubitemid 15153495)
    • (1985) Science , vol.227 , Issue.4685 , pp. 375-381
    • Cerutti, P.A.1
  • 11
    • 67650071137 scopus 로고    scopus 로고
    • Targeting cancer cells by ROS-mediated mechanisms: A radical therapeutic approach?
    • Trachootham D, Alexandre J, Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?. Nat Rev Drug Discov. 2009 ; 8: 579-591
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 579-591
    • Trachootham, D.1    Alexandre, J.2    Huang, P.3
  • 12
    • 27644477094 scopus 로고    scopus 로고
    • Cancer chemoprevention: Scientific promise, clinical uncertainty
    • DOI 10.1038/ncponc0319, PII N0319
    • Sporn MB, Liby KT. Cancer chemoprevention: scientific promise, clinical uncertainty. Nat Clin Pract Oncol. 2005 ; 2: 518-525 (Pubitemid 41553936)
    • (2005) Nature Clinical Practice Oncology , vol.2 , Issue.10 , pp. 518-525
    • Sporn, M.B.1    Liby, K.T.2
  • 13
    • 0037236792 scopus 로고    scopus 로고
    • Anticancer potential of curcumin: Preclinical and clinical studies
    • Aggarwal BB, Kumar A, Bharti AC. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. 2003 ; 23: 363-398 (Pubitemid 36361976)
    • (2003) Anticancer Research , vol.23 , Issue.A1 , pp. 363-398
    • Aggarwal, B.B.1    Kumar, A.2    Bharti, A.C.3
  • 14
    • 0031860081 scopus 로고    scopus 로고
    • Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
    • DOI 10.1055/s-2006-957450
    • Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998 ; 64: 353-356 (Pubitemid 28234275)
    • (1998) Planta Medica , vol.64 , Issue.4 , pp. 353-356
    • Shoba, G.1    Joy, D.2    Joseph, T.3    Majeed, M.4    Rajendran, R.5    Srinivas, P.S.S.R.6
  • 16
    • 61449250919 scopus 로고    scopus 로고
    • Inhibition of benzo[a]pyrene- and cyclophoshamide-induced mutagenicity by Cinnamomum cassia
    • Sharma N, Trikha P,, Athar M, Raisuddin S. Inhibition of benzo[a]pyrene- and cyclophoshamide-induced mutagenicity by Cinnamomum cassia. Mutat Res. 2001 ; 179-188: 480-481
    • (2001) Mutat Res , vol.179-188 , pp. 480-481
    • Sharma, N.1    Trikha, P.2    Athar, M.3    Raisuddin, S.4
  • 17
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Beuge JA, Aust SD. Microsomal lipid peroxidation. Meth Enzymol. 1978 ; 5: 302-310
    • (1978) Meth Enzymol , vol.5 , pp. 302-310
    • Beuge, J.A.1    Aust, S.D.2
  • 18
  • 19
    • 0018327389 scopus 로고
    • Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver
    • Moron MS, Depierre JW, Mannervik B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochim Biophys Acta. 1979 ; 582: 67-78 (Pubitemid 9065588)
    • (1979) Biochimica et Biophysica Acta , vol.582 , Issue.1 , pp. 67-78
    • Moron, M.S.1    Depierre, J.W.2    Mannervik, B.3
  • 21
    • 0021752183 scopus 로고
    • Low activities of glutathione-related enzymes as factors in the genesis of urinary bladder cancer
    • Mohandas J, Marshall JJ, Duggin GG, Horvath JS, Tiller DJ. Low activities of glutathione-related enzymes as factors in the genesis of urinary bladder cancer. Cancer Res. 1984 ; 44: 5086-5091 (Pubitemid 15204468)
    • (1984) Cancer Research , vol.44 , Issue.11 , pp. 5086-5091
    • Mohandas, J.1    Marshall, J.J.2    Duggin, G.G.3
  • 23
    • 0002191974 scopus 로고
    • Bergmeyer HU, ed. New York: Academy Press
    • Luck H Methods of enzymatic analysis. Bergmeyer HU, ed. New York: Academy Press ; 1971: 885-893.
    • (1971) Methods of Enzymatic Analysis , pp. 885-893
    • Luck, H.1
  • 24
    • 0017804313 scopus 로고
    • Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase
    • Kono Y. Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase. Arch Biochem Biophys. 1978 ; 186: 189-195 (Pubitemid 8290500)
    • (1978) Archives of Biochemistry and Biophysics , vol.186 , Issue.1 , pp. 189-195
    • Kono, Y.1
  • 26
    • 0020535865 scopus 로고
    • An application of acridine orange fluorescent staining to the micronuclear test
    • Hayashi M, Sofuni JI, Ishidate M. An application of acridine orange fluorescent staining to the micronucleus test. Mutat Res. 1983 ; 120: 241-247 (Pubitemid 13103085)
    • (1983) Mutation Research , vol.120 , Issue.4 , pp. 241-247
    • Hayashi, M.1    Sofuni, T.2    Ishidate Jr., M.3
  • 27
    • 0020508747 scopus 로고
    • Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases
    • Ames BN. Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science. 1983 ; 22: 1256-1264
    • (1983) Science , vol.22 , pp. 1256-1264
    • Ames, B.N.1
  • 30
    • 0001047585 scopus 로고    scopus 로고
    • Reactive oxygen species: Oxidative damage and pathogenesis
    • Bandyopadhyay U, Das D, Banerjee RK. Reactive oxygen species: oxidative damage and pathogenesis. Curr Sci. 1999 ; 77: 658-666 (Pubitemid 129558409)
    • (1999) Current Science , vol.77 , Issue.5 , pp. 658-666
    • Bandyopadhyay, U.1    Das, D.2    Banerjee, R.K.3
  • 31
    • 35348922189 scopus 로고    scopus 로고
    • Effects of benzo(a)pyrene and ethanol on oxidative stress of brain, lung tissues and lung morphology in rats
    • Emre MH, Aktay G, Polat A, Vardt N. Effects of benzo(a)pyrene and ethanol on oxidative stress of brain, lung tissues and lung morphology in rats. Chin J Physiol. 2007 ; 50: 143-148
    • (2007) Chin J Physiol , vol.50 , pp. 143-148
    • Emre, M.H.1    Aktay, G.2    Polat, A.3    Vardt, N.4
  • 32
    • 0024780087 scopus 로고
    • Current status review: Free radicals, reactive oxygen species and human disease: A critical evaluation with special reference to atherosclerosis
    • Halliwell B. Free radicals, reactive oxygen species and human disease: a critical evaluation with special reference to atherosclerosis. Br J Exp Pathol. 1989 ; 70: 737-757 (Pubitemid 20022141)
    • (1989) British Journal of Experimental Pathology , vol.70 , Issue.6 , pp. 737-757
    • Halliwell, B.1
  • 33
    • 53449087528 scopus 로고    scopus 로고
    • Olive oil protects rat liver microsomes against benzo(a)pyrene-induced oxidative damages: An in vitro study
    • Devi KP, Kiruthiga PV, Pandian SK, Archunan G, Arun S. Olive oil protects rat liver microsomes against benzo(a)pyrene-induced oxidative damages: an in vitro study. Mol Nutr Food Res. 2008 ; 52: 95-102
    • (2008) Mol Nutr Food Res , vol.52 , pp. 95-102
    • Devi, K.P.1    Kiruthiga, P.V.2    Pandian, S.K.3    Archunan, G.4    Arun, S.5
  • 34
    • 77953083779 scopus 로고    scopus 로고
    • An insight into the chemopreventive role of curcumin and quercetin during promotional phase of benzo(a)pyrene-induced lung carcinogenesis in mice
    • Nair P, Malhotra A, Dhawan DK. An insight into the chemopreventive role of curcumin and quercetin during promotional phase of benzo(a)pyrene-induced lung carcinogenesis in mice. Toxicol Environ Chem. 2009 ; 92: 1187-1197
    • (2009) Toxicol Environ Chem , vol.92 , pp. 1187-1197
    • Nair, P.1    Malhotra, A.2    Dhawan, D.K.3
  • 35
    • 27444442482 scopus 로고    scopus 로고
    • Protective role of tetrahydrocurcumin (THC) an active principle of turmeric on chloroquine induced hepatotoxicity in rats
    • Pari L, Amali DR. Protective role of tetrahydrocurcumin (THC) an active principle of turmeric on chloroquine induced hepatotoxicity in rats. J Pharm Pharm Sci. 2005 ; 8: 115-123 (Pubitemid 41528877)
    • (2005) Journal of Pharmacy and Pharmaceutical Sciences , vol.8 , Issue.1 , pp. 115-123
    • Pari, L.1    Amali, D.R.2
  • 36
    • 0024432603 scopus 로고
    • Regulation of cellular glutathione
    • Deneke SM, Fanburg BL. Regulation of cellular glutathione. Am J Physiol. 1989 ; 257: 163-173
    • (1989) Am J Physiol , vol.257 , pp. 163-173
    • Deneke, S.M.1    Fanburg, B.L.2
  • 39
    • 4444322884 scopus 로고    scopus 로고
    • Taurine restores ethanol-induced depletion of antioxidants and attenuates oxidative stress in rat tissues
    • DOI 10.1007/s00726-004-0066-8
    • Pushpakiran G, Mahalakshmi K, Anuradha CV. Taurine restores ethanol-induced depletion of antioxidants and attenuates oxidative stress in rat tissues. Amino Acids. 2004 ; 27: 91-96 (Pubitemid 39178953)
    • (2004) Amino Acids , vol.27 , Issue.1 , pp. 91-96
    • Pushpakiran, G.1    Mahalakshmi, K.2    Anuradha, C.V.3
  • 40
    • 34648825471 scopus 로고    scopus 로고
    • Zinc mediated normalization of histoarchitecture and antioxidant status offers protection against initiation of experimental carcinogenesis
    • DOI 10.1007/s11010-007-9490-x
    • Chadha VD, Vaiphei K, Dhawan DK. Zinc mediated normalization of histoarchitecture and antioxidant status offers protection against initiation of experimental carcinogenesis. Mol cell Biochem. 2007 ; 304: 101-108 (Pubitemid 47456856)
    • (2007) Molecular and Cellular Biochemistry , vol.304 , Issue.1-2 , pp. 101-108
    • Chadha, V.D.1    Vaiphei, K.2    Dhawan, D.K.3
  • 41
    • 34250794390 scopus 로고    scopus 로고
    • Chemopreventive potential of zinc in experimentally induced colon carcinogenesis
    • DOI 10.1016/j.toxlet.2007.02.002, PII S0378427407000616
    • Dani V, Goel A, Vaiphei K, Dhawan DK. Chemopreventive potential of zinc in experimentally induced colon carcinogenesis. Toxicol Lett. 2007 ; 171: 10-18 (Pubitemid 46990664)
    • (2007) Toxicology Letters , vol.171 , Issue.1-2 , pp. 10-18
    • Dani, V.1    Goel, A.2    Vaiphei, K.3    Dhawan, D.K.4
  • 42
    • 0031586757 scopus 로고    scopus 로고
    • Oxidative stress to DNA, protein, and antioxidant enzymes (superoxide dismutase and catalase) in rats treated with benzo(a)pyrene
    • DOI 10.1016/S0304-3835(97)04610-7, PII S0304383597046107
    • Kim KB, Lee BM. Oxidative stress to DNA, protein, and antioxidant enzymes (superoxide dismutase and catalase) in rats treated with benzo(a)pyrene. Cancer Lett. 1997 ; 113: 205-212 (Pubitemid 27113250)
    • (1997) Cancer Letters , vol.113 , Issue.1-2 , pp. 205-212
    • Kim, K.B.1    Lee, B.M.2
  • 43
    • 0028278766 scopus 로고
    • Effect of dietary turmeric (Curcuma longa) on iron-induced lipid peroxidation in the rat liver
    • DOI 10.1016/0278-6915(94)90201-1
    • Reddy AC, Lokesh BR. Effect of dietary turmeric (Curcuma longa) on iron-induced lipid peroxidation in the rat liver. Food Chem Toxicol. 1994 ; 32: 279-283 (Pubitemid 24128085)
    • (1994) Food and Chemical Toxicology , vol.32 , Issue.3 , pp. 279-283
    • Reddy, A.C.P.1    Lokesh, B.R.2
  • 44
    • 0025283870 scopus 로고
    • Antimutagens and anticarcinogens: A survey of putative interceptor molecules
    • DOI 10.1002/em.2850150305
    • Hartman PE, Shankel DM. Antimutagens and anticarcinogens: a survey of putative interceptor molecules. Environ Mol Mutagen. 1990 ; 15: 145-182 (Pubitemid 20179118)
    • (1990) Environmental and Molecular Mutagenesis , vol.15 , Issue.3 , pp. 145-182
    • Hartman, P.E.1    Shankel, D.M.2
  • 45
    • 0031665666 scopus 로고    scopus 로고
    • Glutathione S-transferases and prevention of cellular free radical damage
    • Ketterer B. Glutathione S-transferases and prevention of cellular free radical damage. Free Radic Res. 1998 ; 28: 647-658 (Pubitemid 28454257)
    • (1998) Free Radical Research , vol.28 , Issue.6 , pp. 647-658
    • Ketterer, B.1
  • 47
    • 0345074085 scopus 로고    scopus 로고
    • Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: Possible role in protection against chemical carcinogenesis and toxicity
    • DOI 10.1034/j.1600-0773.2003.920106.x
    • Iqbal M, Sharma SD, Okazaki Y, Fujisawa M, Okada S. Dietary supplementation of curcumin enhances antioxidant and phase II metabolizing enzymes in ddY male mice: possible role in protection against chemical carcinogenesis and toxicity. Pharmacol Toxicol. 2003 ; 92: 33-38 (Pubitemid 36238075)
    • (2003) Pharmacology and Toxicology , vol.92 , Issue.1 , pp. 33-38
    • Iqbal, M.1    Sharma, S.D.2    Okazaki, Y.3    Fujisawa, M.4    Okada, S.5
  • 48
    • 46949104416 scopus 로고    scopus 로고
    • Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: Mechanism of its anti-initiating action
    • DOI 10.1093/carcin/bgn064
    • Garg R, Gupta S, Maru GB. Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action. Carcinogenesis. 2008 ; 29: 1022-1032 (Pubitemid 351982248)
    • (2008) Carcinogenesis , vol.29 , Issue.5 , pp. 1022-1032
    • Garg, R.1    Gupta, S.2    Maru, G.B.3
  • 49
    • 0031691297 scopus 로고    scopus 로고
    • Mechanism of inhibition of benzo[a]pyrene-induced forestomach cancer in mice by dietary curcumin
    • DOI 10.1093/carcin/19.8.1357
    • Singh SV, Hu X, Srivastava SK, Singh M, Xia H, Orchard JL, et al. Mechanism of inhibition of benzo[a]pyrene-induced forestomach cancer in mice by dietary curcumin. Carcinogenesis. 1998 ; 19: 1357-1360 (Pubitemid 28409831)
    • (1998) Carcinogenesis , vol.19 , Issue.8 , pp. 1357-1360
    • Singh, S.V.1    Hu, X.2    Srivastava, S.K.3    Singh, M.4    Xia, H.5    Orchard, J.L.6    Zaren, H.A.7
  • 50
    • 57349163481 scopus 로고    scopus 로고
    • Antigenotoxic effects of curcumin and piperine alone or in combination against 7,12-dimethylbenz(a)anthracene induced genotoxicity in bone marrow of golden Syrian hamsters
    • DOI 10.1080/15376510701781520, PII 901550732
    • Balakrishnan S, Vellaichamy L, Menon VP, Manoharan S. Antigenotoxic effects of curcumin and piperine alone or in combination against 7,12-dimethylbenz(a)anthracene induced genotoxicity in bone marrow of Golden Syrian hamsters. Toxicol Mech Methods. 2008 ; 18: 691-696 (Pubitemid 352790074)
    • (2008) Toxicology Mechanisms and Methods , vol.18 , Issue.9 , pp. 691-696
    • Balakrishnan, S.1    Vellaichamy, L.2    Menon, V.P.3    Manoharan, S.4
  • 52
    • 35948951161 scopus 로고    scopus 로고
    • Black pepper and its pungent principle-piperine: A review of diverse physiological effects
    • DOI 10.1080/10408390601062054, PII 783867875
    • Srinivasan K. Black pepper and its pungent principle-piperine: a review of diverse physiological effects. Crit Rev Food Sci Nutr. 2007 ; 47: 735-748 (Pubitemid 350072517)
    • (2007) Critical Reviews in Food Science and Nutrition , vol.47 , Issue.8 , pp. 735-748
    • Srinivasan, K.1
  • 53
    • 75649095989 scopus 로고    scopus 로고
    • Bioavailability enhancing activities of natural compounds from medicinal plants
    • Kang MJ, Cho JY, Shim BH, Kim DK, Lee J. Bioavailability enhancing activities of natural compounds from medicinal plants. J Med Plants Res. 2009 ; 3: 1204-1211
    • (2009) J Med Plants Res , vol.3 , pp. 1204-1211
    • Kang, M.J.1    Cho, J.Y.2    Shim, B.H.3    Kim, D.K.4    Lee, J.5
  • 54
    • 0025930990 scopus 로고
    • Effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers
    • Bano G, Raina RK, Zutshi U, Bedi KL, Johri RK, Sharma SC. Effect of piperine on bioavailability and pharmacokinetics of propranolol and theophylline in healthy volunteers. Eur J Clin Pharmacol. 1991 ; 41: 615-617
    • (1991) Eur J Clin Pharmacol , vol.41 , pp. 615-617
    • Bano, G.1    Raina, R.K.2    Zutshi, U.3    Bedi, K.L.4    Johri, R.K.5    Sharma, S.C.6
  • 55
    • 77952379134 scopus 로고    scopus 로고
    • Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats
    • Suresh D, Srinivasan K. Tissue distribution & elimination of capsaicin, piperine & curcumin following oral intake in rats. Indian J Med Res. 2010 ; 131: 682-691
    • (2010) Indian J Med Res , vol.131 , pp. 682-691
    • Suresh, D.1    Srinivasan, K.2
  • 56
    • 0036250151 scopus 로고    scopus 로고
    • Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: Influence on brush border membrane fluidity, ultrastructure and enzyme kinetics
    • Khajuria A, Thusu N, Zutshi U. Piperine modulates permeability characteristics of intestine by inducing alterations in membrane dynamics: influence on brush border membrane fluidity, ultrastructure and enzyme kinetics. Phytomedicine. 2002 ; 9: 224-231 (Pubitemid 34475555)
    • (2002) Phytomedicine , vol.9 , Issue.3 , pp. 224-231
    • Khajuria, A.1    Thusu, N.2    Zutshi, U.3
  • 57
    • 5144221545 scopus 로고    scopus 로고
    • Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder
    • DOI 10.1016/j.bcp.2004.07.009, PII S0006295204004800
    • Chearwae W, Anuchapreeda S, Nandigama K, Ambudkar SV, Limtrakul P. Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from turmeric powder. Biochem Pharmacol. 2004 ; 68: 2043-2052 (Pubitemid 39346194)
    • (2004) Biochemical Pharmacology , vol.68 , Issue.10 , pp. 2043-2052
    • Chearwae, W.1    Anuchapreeda, S.2    Nandigama, K.3    Ambudkar, S.V.4    Limtrakul, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.