메뉴 건너뛰기




Volumn 7, Issue 7, 2012, Pages

Overexpression of the DEC1 protein induces senescence in vitro and is related to better survival in esophageal squamous cell carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; DIFFERENTIATED EMBRYO CHONDROCYTE EXPRESSED GENE 1 PROTEIN; TRANSCRIPTION FACTOR; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 84864230998     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041862     Document Type: Article
Times cited : (30)

References (57)
  • 1
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • Ferlay J, Shin HR, Bray F, Forman D, Mathers C, et al. (2010) Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 127: 2893-2917.
    • (2010) Int J Cancer , vol.127 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3    Forman, D.4    Mathers, C.5
  • 3
    • 0033621939 scopus 로고    scopus 로고
    • Topological analysis of p21WAF1/CIP1 expression in esophageal squamous dysplasia
    • Shirakawa Y, Naomoto Y, Kimura M, Kawashima R, Yamatsuji T, et al. (2000) Topological analysis of p21WAF1/CIP1 expression in esophageal squamous dysplasia. Clin Cancer Res 6: 541-550.
    • (2000) Clin Cancer Res , vol.6 , pp. 541-550
    • Shirakawa, Y.1    Naomoto, Y.2    Kimura, M.3    Kawashima, R.4    Yamatsuji, T.5
  • 4
    • 33846588894 scopus 로고    scopus 로고
    • Tissue microarray analysis reveals a tight correlation between protein expression pattern and progression of esophageal squamous cell carcinoma
    • Xue LY, Hu N, Song YM, Zou SM, Shou JZ, et al. (2006) Tissue microarray analysis reveals a tight correlation between protein expression pattern and progression of esophageal squamous cell carcinoma. BMC Cancer 6: 296.
    • (2006) BMC Cancer , vol.6 , pp. 296
    • Xue, L.Y.1    Hu, N.2    Song, Y.M.3    Zou, S.M.4    Shou, J.Z.5
  • 5
    • 19944433844 scopus 로고    scopus 로고
    • Histological precursors of oesophageal squamous cell carcinoma: results from a 13 year prospective follow up study in a high risk population
    • Wang GQ, Abnet CC, Shen Q, Lewin KJ, Sun XD, et al. (2005) Histological precursors of oesophageal squamous cell carcinoma: results from a 13 year prospective follow up study in a high risk population. Gut 54: 187-192.
    • (2005) Gut , vol.54 , pp. 187-192
    • Wang, G.Q.1    Abnet, C.C.2    Shen, Q.3    Lewin, K.J.4    Sun, X.D.5
  • 6
    • 78651454406 scopus 로고    scopus 로고
    • An expert opinion on esophageal cancer therapy
    • Cohen DJ, Ajani J, (2011) An expert opinion on esophageal cancer therapy. Expert Opin Pharmacother 12: 225-239.
    • (2011) Expert Opin Pharmacother , vol.12 , pp. 225-239
    • Cohen, D.J.1    Ajani, J.2
  • 7
    • 0035660618 scopus 로고    scopus 로고
    • Expression of cell cycle regulatory proteins in the multistep process of oesophageal carcinogenesis: stepwise over-expression of cyclin E and p53, reduction of p21(WAF1/CIP1) and dysregulation of cyclin D1 and p27(KIP1)
    • Ohbu M, Kobayashi N, Okayasu I, (2001) Expression of cell cycle regulatory proteins in the multistep process of oesophageal carcinogenesis: stepwise over-expression of cyclin E and p53, reduction of p21(WAF1/CIP1) and dysregulation of cyclin D1 and p27(KIP1). Histopathology 39: 589-596.
    • (2001) Histopathology , vol.39 , pp. 589-596
    • Ohbu, M.1    Kobayashi, N.2    Okayasu, I.3
  • 8
    • 63449126920 scopus 로고    scopus 로고
    • MicroRNA-21 regulates the proliferation and invasion in esophageal squamous cell carcinoma
    • Hiyoshi Y, Kamohara H, Karashima R, Sato N, Imamura Y, et al. (2009) MicroRNA-21 regulates the proliferation and invasion in esophageal squamous cell carcinoma. Clin Cancer Res 15: 1915-1922.
    • (2009) Clin Cancer Res , vol.15 , pp. 1915-1922
    • Hiyoshi, Y.1    Kamohara, H.2    Karashima, R.3    Sato, N.4    Imamura, Y.5
  • 9
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick L, Moorhead PS, (1961) The serial cultivation of human diploid cell strains. Exp Cell Res 25: 585-621.
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 10
    • 50549218525 scopus 로고
    • The Limited in Vitro Lifetime of Human Diploid Cell Strains
    • Hayflick L, (1965) The Limited in Vitro Lifetime of Human Diploid Cell Strains. Exp Cell Res 37: 614-636.
    • (1965) Exp Cell Res , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 11
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB, Greider CW, (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345: 458-460.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 12
    • 14644410453 scopus 로고    scopus 로고
    • The signals and pathways activating cellular senescence
    • Ben-Porath I, Weinberg RA, (2005) The signals and pathways activating cellular senescence. Int J Biochem Cell Biol 37: 961-976.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 961-976
    • Ben-Porath, I.1    Weinberg, R.A.2
  • 13
    • 52949152429 scopus 로고    scopus 로고
    • Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation
    • Gewirtz DA, Holt SE, Elmore LW, (2008) Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation. Biochem Pharmacol 76: 947-957.
    • (2008) Biochem Pharmacol , vol.76 , pp. 947-957
    • Gewirtz, D.A.1    Holt, S.E.2    Elmore, L.W.3
  • 14
    • 70349093119 scopus 로고    scopus 로고
    • Senescence impairs successful reprogramming to pluripotent stem cells
    • Banito A, Rashid ST, Acosta JC, Li S, Pereira CF, et al. (2009) Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev 23: 2134-2139.
    • (2009) Genes Dev , vol.23 , pp. 2134-2139
    • Banito, A.1    Rashid, S.T.2    Acosta, J.C.3    Li, S.4    Pereira, C.F.5
  • 15
    • 33748422079 scopus 로고    scopus 로고
    • Oncogene-induced cell senescence-halting on the road to cancer
    • Mooi WJ, Peeper DS, (2006) Oncogene-induced cell senescence-halting on the road to cancer. N Engl J Med 355: 1037-1046.
    • (2006) N Engl J Med , vol.355 , pp. 1037-1046
    • Mooi, W.J.1    Peeper, D.S.2
  • 17
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: when bad things happen to good cells
    • Campisi J, d'Adda di Fagagna F, (2007) Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 8: 729-740.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 729-740
    • Campisi, J.1    d'Adda di Fagagna, F.2
  • 19
    • 23244461708 scopus 로고    scopus 로고
    • Oncogene-induced senescence as an initial barrier in lymphoma development
    • Braig M, Lee S, Loddenkemper C, Rudolph C, Peters AH, et al. (2005) Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 436: 660-665.
    • (2005) Nature , vol.436 , pp. 660-665
    • Braig, M.1    Lee, S.2    Loddenkemper, C.3    Rudolph, C.4    Peters, A.H.5
  • 20
    • 23244460597 scopus 로고    scopus 로고
    • Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
    • Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, et al. (2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436: 725-730.
    • (2005) Nature , vol.436 , pp. 725-730
    • Chen, Z.1    Trotman, L.C.2    Shaffer, D.3    Lin, H.K.4    Dotan, Z.A.5
  • 22
    • 0030766777 scopus 로고    scopus 로고
    • Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells
    • Boudjelal M, Taneja R, Matsubara S, Bouillet P, Dolle P, et al. (1997) Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells. Genes Dev 11: 2052-2065.
    • (1997) Genes Dev , vol.11 , pp. 2052-2065
    • Boudjelal, M.1    Taneja, R.2    Matsubara, S.3    Bouillet, P.4    Dolle, P.5
  • 23
    • 0031577301 scopus 로고    scopus 로고
    • Molecular characterization of the novel basic helix-loop-helix protein DEC1 expressed in differentiated human embryo chondrocytes
    • Shen M, Kawamoto T, Yan W, Nakamasu K, Tamagami M, et al. (1997) Molecular characterization of the novel basic helix-loop-helix protein DEC1 expressed in differentiated human embryo chondrocytes. Biochem Biophys Res Commun 236: 294-298.
    • (1997) Biochem Biophys Res Commun , vol.236 , pp. 294-298
    • Shen, M.1    Kawamoto, T.2    Yan, W.3    Nakamasu, K.4    Tamagami, M.5
  • 25
    • 41449091585 scopus 로고    scopus 로고
    • DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence
    • Qian Y, Zhang J, Yan B, Chen X, (2008) DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence. J Biol Chem 283: 2896-2905.
    • (2008) J Biol Chem , vol.283 , pp. 2896-2905
    • Qian, Y.1    Zhang, J.2    Yan, B.3    Chen, X.4
  • 26
    • 0034635983 scopus 로고    scopus 로고
    • Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms
    • Sun H, Taneja R, (2000) Stra13 expression is associated with growth arrest and represses transcription through histone deacetylase (HDAC)-dependent and HDAC-independent mechanisms. Proc Natl Acad Sci U S A 97: 4058-4063.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 4058-4063
    • Sun, H.1    Taneja, R.2
  • 27
    • 33745712849 scopus 로고    scopus 로고
    • The power and the promise of oncogene-induced senescence markers
    • Collado M, Serrano M, (2006) The power and the promise of oncogene-induced senescence markers. Nat Rev Cancer 6: 472-476.
    • (2006) Nat Rev Cancer , vol.6 , pp. 472-476
    • Collado, M.1    Serrano, M.2
  • 28
    • 3242711377 scopus 로고    scopus 로고
    • The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissues and tumours
    • Turley H, Wykoff CC, Troup S, Watson PH, Gatter KC, et al. (2004) The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissues and tumours. J Pathol 203: 808-813.
    • (2004) J Pathol , vol.203 , pp. 808-813
    • Turley, H.1    Wykoff, C.C.2    Troup, S.3    Watson, P.H.4    Gatter, K.C.5
  • 29
    • 4644312033 scopus 로고    scopus 로고
    • The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers
    • Chakrabarti J, Turley H, Campo L, Han C, Harris AL, et al. (2004) The transcription factor DEC1 (stra13, SHARP2) is associated with the hypoxic response and high tumour grade in human breast cancers. Br J Cancer 91: 954-958.
    • (2004) Br J Cancer , vol.91 , pp. 954-958
    • Chakrabarti, J.1    Turley, H.2    Campo, L.3    Han, C.4    Harris, A.L.5
  • 30
    • 69249120887 scopus 로고    scopus 로고
    • The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in gastric cancer
    • Zheng Y, Jia Y, Wang Y, Wang M, Li B, et al. (2009) The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in gastric cancer. OMICS 13: 301-306.
    • (2009) OMICS , vol.13 , pp. 301-306
    • Zheng, Y.1    Jia, Y.2    Wang, Y.3    Wang, M.4    Li, B.5
  • 31
    • 0037108919 scopus 로고    scopus 로고
    • Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation
    • Li Y, Zhang H, Xie M, Hu M, Ge S, et al. (2002) Abundant expression of Dec1/stra13/sharp2 in colon carcinoma: its antagonizing role in serum deprivation-induced apoptosis and selective inhibition of procaspase activation. Biochem J 367: 413-422.
    • (2002) Biochem J , vol.367 , pp. 413-422
    • Li, Y.1    Zhang, H.2    Xie, M.3    Hu, M.4    Ge, S.5
  • 32
    • 0037531790 scopus 로고    scopus 로고
    • DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer
    • Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Wykoff CC, et al. (2003) DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. J Pathol 200: 222-228.
    • (2003) J Pathol , vol.200 , pp. 222-228
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3    Turley, H.4    Wykoff, C.C.5
  • 33
    • 79955935685 scopus 로고    scopus 로고
    • DEC1 nuclear expression: a marker of differentiation grade in hepatocellular carcinoma
    • Shi XH, Zheng Y, Sun Q, Cui J, Liu QH, et al. (2011) DEC1 nuclear expression: a marker of differentiation grade in hepatocellular carcinoma. World J Gastroenterol 17: 2037-2043.
    • (2011) World J Gastroenterol , vol.17 , pp. 2037-2043
    • Shi, X.H.1    Zheng, Y.2    Sun, Q.3    Cui, J.4    Liu, Q.H.5
  • 34
    • 77958153013 scopus 로고    scopus 로고
    • Hypoxia inducible BHLHB2 is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma
    • Wang W, Reiser-Erkan C, Michalski CW, Raggi MC, Quan L, et al. (2010) Hypoxia inducible BHLHB2 is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. Biochem Biophys Res Commun 401: 422-428.
    • (2010) Biochem Biophys Res Commun , vol.401 , pp. 422-428
    • Wang, W.1    Reiser-Erkan, C.2    Michalski, C.W.3    Raggi, M.C.4    Quan, L.5
  • 35
    • 0036725992 scopus 로고    scopus 로고
    • Senescence-like changes induced by expression of p21(waf1/Cip1) in NIH3T3 cell line
    • Chen X, Zhang W, Gao YF, Su XQ, Zhai ZH, (2002) Senescence-like changes induced by expression of p21(waf1/Cip1) in NIH3T3 cell line. Cell Res 12: 229-233.
    • (2002) Cell Res , vol.12 , pp. 229-233
    • Chen, X.1    Zhang, W.2    Gao, Y.F.3    Su, X.Q.4    Zhai, Z.H.5
  • 37
    • 33845485257 scopus 로고    scopus 로고
    • Epidemiology and pathogenesis of esophageal cancer
    • Holmes RS, Vaughan TL, (2007) Epidemiology and pathogenesis of esophageal cancer. Semin Radiat Oncol 17: 2-9.
    • (2007) Semin Radiat Oncol , vol.17 , pp. 2-9
    • Holmes, R.S.1    Vaughan, T.L.2
  • 38
    • 23244463191 scopus 로고    scopus 로고
    • Differential protein expression between esophageal squamous cell carcinoma and dysplasia, and prognostic significance of protein markers
    • Chang MS, Lee HS, Lee BL, Kim YT, Lee JS, et al. (2005) Differential protein expression between esophageal squamous cell carcinoma and dysplasia, and prognostic significance of protein markers. Pathol Res Pract 201: 417-425.
    • (2005) Pathol Res Pract , vol.201 , pp. 417-425
    • Chang, M.S.1    Lee, H.S.2    Lee, B.L.3    Kim, Y.T.4    Lee, J.S.5
  • 39
    • 66149134040 scopus 로고    scopus 로고
    • Genomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers
    • Kashyap MK, Marimuthu A, Kishore CJ, Peri S, Keerthikumar S, et al. (2009) Genomewide mRNA profiling of esophageal squamous cell carcinoma for identification of cancer biomarkers. Cancer Biol Ther 8: 36-46.
    • (2009) Cancer Biol Ther , vol.8 , pp. 36-46
    • Kashyap, M.K.1    Marimuthu, A.2    Kishore, C.J.3    Peri, S.4    Keerthikumar, S.5
  • 40
    • 33750454439 scopus 로고    scopus 로고
    • Predictive and prognostic molecular markers in outcome of esophageal cancer
    • Vallbohmer D, Lenz HJ, (2006) Predictive and prognostic molecular markers in outcome of esophageal cancer. Dis Esophagus 19: 425-432.
    • (2006) Dis Esophagus , vol.19 , pp. 425-432
    • Vallbohmer, D.1    Lenz, H.J.2
  • 41
    • 33645526114 scopus 로고    scopus 로고
    • Oncogene-induced senescence: putting the brakes on tumor development
    • Braig M, Schmitt CA, (2006) Oncogene-induced senescence: putting the brakes on tumor development. Cancer Res 66: 2881-2884.
    • (2006) Cancer Res , vol.66 , pp. 2881-2884
    • Braig, M.1    Schmitt, C.A.2
  • 42
    • 78649629320 scopus 로고    scopus 로고
    • Oncogene-induced senescence: the bright and dark side of the response
    • Gorgoulis VG, Halazonetis TD, (2010) Oncogene-induced senescence: the bright and dark side of the response. Curr Opin Cell Biol 22: 816-827.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 816-827
    • Gorgoulis, V.G.1    Halazonetis, T.D.2
  • 43
    • 33845235459 scopus 로고    scopus 로고
    • Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
    • Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, et al. (2006) Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444: 633-637.
    • (2006) Nature , vol.444 , pp. 633-637
    • Bartkova, J.1    Rezaei, N.2    Liontos, M.3    Karakaidos, P.4    Kletsas, D.5
  • 44
    • 41549149451 scopus 로고    scopus 로고
    • Cellular senescence in vivo: a barrier to tumorigenesis
    • Prieur A, Peeper DS, (2008) Cellular senescence in vivo: a barrier to tumorigenesis. Curr Opin Cell Biol 20: 150-155.
    • (2008) Curr Opin Cell Biol , vol.20 , pp. 150-155
    • Prieur, A.1    Peeper, D.S.2
  • 45
    • 84855443905 scopus 로고    scopus 로고
    • TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence
    • Skinner HD, Sandulache VC, Ow TJ, Meyn RE, Yordy JS, et al. (2012) TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence. Clin Cancer Res 18: 290-300.
    • (2012) Clin Cancer Res , vol.18 , pp. 290-300
    • Skinner, H.D.1    Sandulache, V.C.2    Ow, T.J.3    Meyn, R.E.4    Yordy, J.S.5
  • 47
    • 34247897276 scopus 로고    scopus 로고
    • Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis
    • Sarkisian CJ, Keister BA, Stairs DB, Boxer RB, Moody SE, et al. (2007) Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. Nat Cell Biol 9: 493-505.
    • (2007) Nat Cell Biol , vol.9 , pp. 493-505
    • Sarkisian, C.J.1    Keister, B.A.2    Stairs, D.B.3    Boxer, R.B.4    Moody, S.E.5
  • 48
    • 0028834114 scopus 로고
    • Frequent microsatellite alterations on chromosome 3p in esophageal squamous cell carcinoma
    • Ogasawara S, Maesawa C, Tamura G, Satodate R, (1995) Frequent microsatellite alterations on chromosome 3p in esophageal squamous cell carcinoma. Cancer Res 55: 891-894.
    • (1995) Cancer Res , vol.55 , pp. 891-894
    • Ogasawara, S.1    Maesawa, C.2    Tamura, G.3    Satodate, R.4
  • 49
    • 77954893634 scopus 로고    scopus 로고
    • Study of abnormal chromosome regions in esophageal squamous cell carcinoma by comparative genomic hybridization: relationship of lymph node metastasis and distant metastasis to selected abnormal regions
    • Sakai N, Kajiyama Y, Iwanuma Y, Tomita N, Amano T, et al. (2010) Study of abnormal chromosome regions in esophageal squamous cell carcinoma by comparative genomic hybridization: relationship of lymph node metastasis and distant metastasis to selected abnormal regions. Dis Esophagus 23: 415-421.
    • (2010) Dis Esophagus , vol.23 , pp. 415-421
    • Sakai, N.1    Kajiyama, Y.2    Iwanuma, Y.3    Tomita, N.4    Amano, T.5
  • 50
    • 80052767384 scopus 로고    scopus 로고
    • Mapping of genetic deletions on chromosome 3 in colorectal cancer: loss of 3p25-pter is associated with distant metastasis and poor survival
    • Tsai MH, Fang WH, Lin SH, Tzeng ST, Huang CS, et al. (2011) Mapping of genetic deletions on chromosome 3 in colorectal cancer: loss of 3p25-pter is associated with distant metastasis and poor survival. Ann Surg Oncol 18: 2662-2670.
    • (2011) Ann Surg Oncol , vol.18 , pp. 2662-2670
    • Tsai, M.H.1    Fang, W.H.2    Lin, S.H.3    Tzeng, S.T.4    Huang, C.S.5
  • 51
    • 13944270339 scopus 로고    scopus 로고
    • Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors
    • Campisi J, (2005) Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell 120: 513-522.
    • (2005) Cell , vol.120 , pp. 513-522
    • Campisi, J.1
  • 52
    • 84861469589 scopus 로고    scopus 로고
    • Cellular senescence: a double-edged sword in the fight against cancer
    • Ohtani N, Takahashi A, Mann DJ, Hara E, (2012) Cellular senescence: a double-edged sword in the fight against cancer. Exp Dermatol 21: 1-4.
    • (2012) Exp Dermatol , vol.21 , pp. 1-4
    • Ohtani, N.1    Takahashi, A.2    Mann, D.J.3    Hara, E.4
  • 53
    • 82755160671 scopus 로고    scopus 로고
    • Epigenetic alterations associated with cellular senescence: A barrier against tumorigenesis or a red carpet for cancer?
    • Decottignies A, d'Adda di Fagagna F, (2011) Epigenetic alterations associated with cellular senescence: A barrier against tumorigenesis or a red carpet for cancer? Semin Cancer Biol 21: 360-366.
    • (2011) Semin Cancer Biol , vol.21 , pp. 360-366
    • Decottignies, A.1    d'Adda di Fagagna, F.2
  • 54
    • 75449097024 scopus 로고    scopus 로고
    • Oncogene-induced cellular senescence
    • Chandeck C, Mooi WJ, (2010) Oncogene-induced cellular senescence. Adv Anat Pathol 17: 42-48.
    • (2010) Adv Anat Pathol , vol.17 , pp. 42-48
    • Chandeck, C.1    Mooi, W.J.2
  • 55
    • 0031822837 scopus 로고    scopus 로고
    • Tissue microarrays for high-throughput molecular profiling of tumor specimens
    • Kononen J, Bubendorf L, Kallioniemi A, Barlund M, Schraml P, et al. (1998) Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 4: 844-847.
    • (1998) Nat Med , vol.4 , pp. 844-847
    • Kononen, J.1    Bubendorf, L.2    Kallioniemi, A.3    Barlund, M.4    Schraml, P.5
  • 56
    • 12244275736 scopus 로고    scopus 로고
    • [Establishment and comparative genomic hybridization analysis of human esophageal carcinomas cell line EC9706]
    • Han Y, Wei F, Xu X, Cai Y, Chen B, et al. (2002) [Establishment and comparative genomic hybridization analysis of human esophageal carcinomas cell line EC9706]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 19: 455-457.
    • (2002) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.19 , pp. 455-457
    • Han, Y.1    Wei, F.2    Xu, X.3    Cai, Y.4    Chen, B.5
  • 57
    • 74949127989 scopus 로고    scopus 로고
    • Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo
    • Debacq-Chainiaux F, Erusalimsky JD, Campisi J, Toussaint O, (2009) Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo. Nat Protoc 4: 1798-1806.
    • (2009) Nat Protoc , vol.4 , pp. 1798-1806
    • Debacq-Chainiaux, F.1    Erusalimsky, J.D.2    Campisi, J.3    Toussaint, O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.