Effect of endoplasmic reticulum stress on inflammation and adiponectin regulation in human adipocytes

Metabolic Syndrome and Related Disorders

Volumn 10, Issue 4, 2012, Pages 297-306

  Mondal, Ashis K ^a   Das, Swapan K ^a   Varma, Vijayalakshmi ^b   Nolen, Greg T ^b   McGehee, Robert E ^c   Elbein, Steven C ^a   Wei, Jeanne Y ^d   Ranganathan, Gouri ^d  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; BIOLOGICAL MARKER; CHAPERONE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; I KAPPA B ALPHA; INITIATION FACTOR 2ALPHA; MESSENGER RNA; PALMITIC ACID; THAPSIGARGIN; TUMOR NECROSIS FACTOR ALPHA; TUNICAMYCIN;

ADIPOCYTE; ARTICLE; CELL GROWTH; CONTROLLED STUDY; DNA DAMAGE; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; INFLAMMATION; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MULTIMERIZATION; PROTEIN PHOSPHORYLATION; RNA SPLICING; STEM CELL; UPREGULATION;

ADIPOCYTES; ADIPONECTIN; BODY MASS INDEX; CELL LINE; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; PALMITIC ACID; PHOSPHORYLATION; RNA; RNA, MESSENGER; STEM CELLS; THAPSIGARGIN; TUNICAMYCIN;

EID: 84864211208     PISSN: 15404196     EISSN: 15578518     Source Type: Journal    
DOI: 10.1089/met.2012.0002     Document Type: Article

References (34)

1. Ozcan U, Cao Q, Yilmaz E, et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004;306:457-461. (Pubitemid 39372439)
2. Wu J, Kaufman RJ. From acute ER stress to physiological roles of the unfolded protein response. Cell Death Differ 2006;13:374-384.
3. Oh DK, Ciaraldi T, Henry RR. Adiponectin in health and disease. Diabetes Obes Metab 2007;9:282-289. (Pubitemid 46502045)
4. Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Circ Res 2005;96:939-949. (Pubitemid 40712793)
5. Wang Y, Lam KS, Yau MH, Xu A. Post-translational modifications of adiponectin: Mechanisms and functional implications. Biochem J 2008;409:623-633. (Pubitemid 351214189)
6. Pajvani UB, Hawkins M, Combs TP, et al. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem 2004;279:12152-12162. (Pubitemid 38445780)
7. Tonelli J, Li W, Kishore P, et al. Mechanisms of early insulinsensitizing effects of thiazolidinediones in type 2 diabetes. Diabetes 2004;53:1621-1629. (Pubitemid 38697679)
8. Nakatani Y, Kaneto H, Kawamori D, et al. Involvement of endoplasmic reticulum stress in insulin resistance and diabetes. J Biol Chem 2005;280:847-851. (Pubitemid 40165054)
9. Rodbell M. Metabolism of isolated fat cells. I. Effects of hormone on glucose metabolism and lipolysis. J Biol Chem 1964;239:375-380.
10. Di Gregorio GB, Yao-Borengasser A, Rasouli N, et al. Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: Association with cytokine expression, insulin resistance, and reduction by pioglitazone. Diabetes 2005; 54:2305-2313. (Pubitemid 41134256)
11. Van Harmelen.V., Skurk T, Rohrig K, et al. Effect of BMI and age on adipose tissue cellularity and differentiation capacity in women. Int J Obes Relat Metab Disord 2003; 27:889-895. (Pubitemid 36918609)
12. Das SK, Chu WS, Mondal AK, et al. Effect of pioglitazone treatment on endoplasmic reticulum stress response in human adipose and in palmitate-induced stress in human liver and adipose cell lines. Am J Physiol Endocrinol Metab 2008; 295:E393-E400.
13. Wang ZV, Schraw TD, Kim JY, et al. Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention. Mol Cell Biol 2007;27:3716-3731. (Pubitemid 46726179)
14. Boden G, Duan X, Homko C, et al. Increase in endoplasmic reticulum (ER) stress related proteins and genes in adipose tissue of obese, insulin resistant individuals. Diabetes 2008; 57:2438-2444.
15. Yamauchi T, Kamon J, Waki H, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nature Med 2001;7:941-946. (Pubitemid 32756432)
16. Altomonte J, Harbaran S, Richter A, et al. Fat depot-specific expression of adiponectin is impaired in Zucker fatty rats. Metab Clin Exper 2003;52:958-963. (Pubitemid 37098362)
17. Hosogai N, Fukuhara A, Oshima K, et al. Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes 2007;56:901-911. (Pubitemid 46525054)
18. Zhou L, Liu M, Zhang J, et al. DsbA-L alleviates endoplasmic reticulum stress-induced adiponectin downregulation. Diabetes 2010;59:2809-2816.
19. Hotamisligil GS. Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes. Diabetes 2005;54(Suppl 2):S73-S78. (Pubitemid 43343334)
20. Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science 2005;307:384-387. (Pubitemid 40139974)
21. Koh EH, Park JY, Park HS, et al. Essential role of mitochondrial function in adiponectin synthesis in adipocytes. Diabetes 2007;56:2973-2981.
22. Trayhurn P, Wang B, Wood IS. Hypoxia in adipose tissue: A basis for the dysregulation of tissue function in obesity? Br J Nutr 2008;100:227-235.
23. Das SK, Sharma NK, Hasstedt SJ, et al. An integrative genomics approach identifies activation of thioredoxin/thioredoxin reductase-1-mediated oxidative stress defense pathway and inhibition of angiogenesis in obese nondiabetic human subjects. J Clin Endocrinol Metab 2011;96:E1308-E1313.
24. Sharma NK, Das SK, Mondal AK, et al. Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects. J Clin Endocrinol Metab 2008;93:4532-4541. (Pubitemid 352789557)
25. Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007;8:519-529. (Pubitemid 46985379)
26. Kern PA, Di Gregorio GB, Lu T, et al. Adiponectin expression from human adipose tissue: Relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression. Diabetes 2003;52:1779-1785. (Pubitemid 36792470)
27. Lara-Castro C, Luo N, Wallace P, et al. Adiponectin multimeric complexes and the metabolic syndrome trait cluster. Diabetes 2006;55:249-259. (Pubitemid 43343322)
28. Novoa I, Zeng H, Harding HP, et al. Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J Cell Biol 2001;153:1011-1022.
29. Bastard JP, Maachi M, Lagathu C, et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw 2006;17:4-12.
30. Bakkar N, Guttridge DC. NF-kappaB signaling: A tale of two pathways in skeletal myogenesis. Physiol Rev 2010;90: 495-511.
31. Ouchi N, Kihara S, Arita Y, et al. Adiponectin, an adipocytederived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway. Circulation 2000;102:1296-1301.
32. Ruan H, Pownall HJ, Lodish HF. Troglitazone antagonizes tumor necrosis factor-alpha-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-kappaB. J Biol Chem 2003;278: 28181-28192. (Pubitemid 36900018)
33. Kassardjian A, Kreydiyyeh SI. JNK modulates the effect of caspases and NF-kappaB in the TNFalpha-induced downregulation of Na+/K+ATPase in HepG2 cells. J Cell Physiol 2008;216:615-620.
34. Neumeier M, Weigert J, Schaffler A, et al. Different effects of adiponectin isoforms in human monocytic cells. J Leukoc Biol 2006;79:803-808. (Pubitemid 44835612)