-
1
-
-
0027953771
-
Hox genes in vertebrate development
-
Krumlauf R, (1994) Hox genes in vertebrate development. Cell 78: 191-201.
-
(1994)
Cell
, vol.78
, pp. 191-201
-
-
Krumlauf, R.1
-
2
-
-
0036782277
-
Deregulated homeobox gene expression in cancer: cause or consequence?
-
Abate-Shen C, (2002) Deregulated homeobox gene expression in cancer: cause or consequence? Nat Rev Cancer 2: 777-785.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 777-785
-
-
Abate-Shen, C.1
-
3
-
-
19944427423
-
Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model
-
Iwasaki M, Kuwata T, Yamazaki Y, Jenkins NA, Copeland NG, et al. (2005) Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood 105: 784-793.
-
(2005)
Blood
, vol.105
, pp. 784-793
-
-
Iwasaki, M.1
Kuwata, T.2
Yamazaki, Y.3
Jenkins, N.A.4
Copeland, N.G.5
-
4
-
-
0032126633
-
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
-
Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, et al. (1998) Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J 17: 3714-3725.
-
(1998)
EMBO J
, vol.17
, pp. 3714-3725
-
-
Kroon, E.1
Krosl, J.2
Thorsteinsdottir, U.3
Baban, S.4
Buchberg, A.M.5
-
5
-
-
33750328319
-
HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition
-
Wu X, Chen H, Parker B, Rubin E, Zhu T, et al. (2006) HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition. Cancer Res 66: 9527-9534.
-
(2006)
Cancer Res
, vol.66
, pp. 9527-9534
-
-
Wu, X.1
Chen, H.2
Parker, B.3
Rubin, E.4
Zhu, T.5
-
6
-
-
33750598939
-
The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer
-
Ma XJ, Hilsenbeck SG, Wang W, Ding L, Sgroi DC, et al. (2006) The HOXB13:IL17BR expression index is a prognostic factor in early-stage breast cancer. J Clin Oncol 24: 4611-4619.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4611-4619
-
-
Ma, X.J.1
Hilsenbeck, S.G.2
Wang, W.3
Ding, L.4
Sgroi, D.C.5
-
7
-
-
2942578063
-
A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen
-
Ma XJ, Wang Z, Ryan PD, Isakoff SJ, Barmettler A, et al. (2004) A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell 5: 607-616.
-
(2004)
Cancer Cell
, vol.5
, pp. 607-616
-
-
Ma, X.J.1
Wang, Z.2
Ryan, P.D.3
Isakoff, S.J.4
Barmettler, A.5
-
8
-
-
0347986652
-
HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8
-
Chen H, Chung S, Sukumar S, (2004) HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8. Mol Cell Biol 24: 924-935.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 924-935
-
-
Chen, H.1
Chung, S.2
Sukumar, S.3
-
9
-
-
0034702232
-
Compromised HOXA5 function can limit p53 expression in human breast tumours
-
Raman V, Martensen SA, Reisman D, Evron E, Odenwald WF, et al. (2000) Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature 405: 974-978.
-
(2000)
Nature
, vol.405
, pp. 974-978
-
-
Raman, V.1
Martensen, S.A.2
Reisman, D.3
Evron, E.4
Odenwald, W.F.5
-
11
-
-
0031019639
-
Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain-demonstration of Hox-dependent targeting of E2a-Pbx1 in vivo
-
Lu Q, Kamps MP, (1997) Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specifities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain-demonstration of Hox-dependent targeting of E2a-Pbx1 in vivo. Oncogene 14: 75-83.
-
(1997)
Oncogene
, vol.14
, pp. 75-83
-
-
Lu, Q.1
Kamps, M.P.2
-
12
-
-
0028947525
-
Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins
-
Chang CP, Shen WF, Rozenfeld S, Lawrence HJ, Largman C, et al. (1995) Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. Genes Dev 9: 663-674.
-
(1995)
Genes Dev
, vol.9
, pp. 663-674
-
-
Chang, C.P.1
Shen, W.F.2
Rozenfeld, S.3
Lawrence, H.J.4
Largman, C.5
-
13
-
-
0029054140
-
Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes
-
Lu Q, Knoepfler PS, Scheele J, Wright DD, Kamps MP, (1995) Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes. Mol Cell Biol 15: 3786-3795.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3786-3795
-
-
Lu, Q.1
Knoepfler, P.S.2
Scheele, J.3
Wright, D.D.4
Kamps, M.P.5
-
14
-
-
0034796574
-
The HOX homeodomain proteins block CBP histone acetyltransferase activity
-
Shen WF, Krishnan K, Lawrence HJ, Largman C, (2001) The HOX homeodomain proteins block CBP histone acetyltransferase activity. Mol Cell Biol 21: 7509-7522.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7509-7522
-
-
Shen, W.F.1
Krishnan, K.2
Lawrence, H.J.3
Largman, C.4
-
15
-
-
33644917701
-
Smads oppose Hox transcriptional activities
-
Li X, Nie S, Chang C, Qiu T, Cao X, (2006) Smads oppose Hox transcriptional activities. Exp Cell Res 312: 854-864.
-
(2006)
Exp Cell Res
, vol.312
, pp. 854-864
-
-
Li, X.1
Nie, S.2
Chang, C.3
Qiu, T.4
Cao, X.5
-
16
-
-
23344431857
-
Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability
-
Williams TM, Williams ME, Heaton JH, Gelehrter TD, Innis JW, (2005) Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability. Nucleic Acids Res 33: 4475-4484.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4475-4484
-
-
Williams, T.M.1
Williams, M.E.2
Heaton, J.H.3
Gelehrter, T.D.4
Innis, J.W.5
-
17
-
-
33847713655
-
A role for the HOXB7 homeodomain protein in DNA repair
-
Rubin E, Wu X, Zhu T, Cheung JC, Chen H, et al. (2007) A role for the HOXB7 homeodomain protein in DNA repair. Cancer Res 67: 1527-1535.
-
(2007)
Cancer Res
, vol.67
, pp. 1527-1535
-
-
Rubin, E.1
Wu, X.2
Zhu, T.3
Cheung, J.C.4
Chen, H.5
-
18
-
-
18944390248
-
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
-
Jagtap P, Szabo C, (2005) Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov 4: 421-440.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 421-440
-
-
Jagtap, P.1
Szabo, C.2
-
19
-
-
24344454692
-
Poly(ADP-ribosyl)ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal
-
Kim MY, Zhang T, Kraus WL, (2005) Poly(ADP-ribosyl)ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal. Genes Dev 19: 1951-1967.
-
(2005)
Genes Dev
, vol.19
, pp. 1951-1967
-
-
Kim, M.Y.1
Zhang, T.2
Kraus, W.L.3
-
20
-
-
0034615948
-
Poly(ADP-ribose) polymerase is a B-MYB coactivator
-
Cervellera MN, Sala A, (2000) Poly(ADP-ribose) polymerase is a B-MYB coactivator. J Biol Chem 275: 10692-10696.
-
(2000)
J Biol Chem
, vol.275
, pp. 10692-10696
-
-
Cervellera, M.N.1
Sala, A.2
-
21
-
-
0035857099
-
PARP co-activates B-MYB through enhanced phosphorylation at cyclin/cdk2 sites
-
Santilli G, Cervellera MN, Johnson TK, Lewis RE, Iacobelli S, et al. (2001) PARP co-activates B-MYB through enhanced phosphorylation at cyclin/cdk2 sites. Oncogene 20: 8167-8174.
-
(2001)
Oncogene
, vol.20
, pp. 8167-8174
-
-
Santilli, G.1
Cervellera, M.N.2
Johnson, T.K.3
Lewis, R.E.4
Iacobelli, S.5
-
22
-
-
0033953753
-
Identification of poly(ADP-ribose) polymerase as a transcriptional coactivator of the human T-cell leukemia virus type 1 Tax protein
-
Anderson MG, Scoggin KE, Simbulan-Rosenthal CM, Steadman JA, (2000) Identification of poly(ADP-ribose) polymerase as a transcriptional coactivator of the human T-cell leukemia virus type 1 Tax protein. J Virol 74: 2169-2177.
-
(2000)
J Virol
, vol.74
, pp. 2169-2177
-
-
Anderson, M.G.1
Scoggin, K.E.2
Simbulan-Rosenthal, C.M.3
Steadman, J.A.4
-
23
-
-
40349108704
-
Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expression
-
Elser M, Borsig L, Hassa PO, Erener S, Messner S, et al. (2008) Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expression. Mol Cancer Res 6: 282-290.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 282-290
-
-
Elser, M.1
Borsig, L.2
Hassa, P.O.3
Erener, S.4
Messner, S.5
-
24
-
-
0031558781
-
Interaction of the transcription factor YY1 with human poly(ADP-ribosyl) transferase
-
Oei SL, Griesenbeck J, Schweiger M, Babich V, Kropotov A, et al. (1997) Interaction of the transcription factor YY1 with human poly(ADP-ribosyl) transferase. Biochem Biophys Res Commun 240: 108-111.
-
(1997)
Biochem Biophys Res Commun
, vol.240
, pp. 108-111
-
-
Oei, S.L.1
Griesenbeck, J.2
Schweiger, M.3
Babich, V.4
Kropotov, A.5
-
25
-
-
0032959888
-
Poly(ADP-ribose) polymerase binds with transcription enhancer factor 1 to MCAT1 elements to regulate muscle-specific transcription
-
Butler AJ, Ordahl CP, (1999) Poly(ADP-ribose) polymerase binds with transcription enhancer factor 1 to MCAT1 elements to regulate muscle-specific transcription. Mol Cell Biol 19: 296-306.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 296-306
-
-
Butler, A.J.1
Ordahl, C.P.2
-
26
-
-
33745255099
-
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription
-
Ju BG, Lunyak VV, Perissi V, Garcia-Bassets I, Rose DW, et al. (2006) A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science 312: 1798-1802.
-
(2006)
Science
, vol.312
, pp. 1798-1802
-
-
Ju, B.G.1
Lunyak, V.V.2
Perissi, V.3
Garcia-Bassets, I.4
Rose, D.W.5
-
27
-
-
0035937826
-
A role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expression
-
Nirodi C, NagDas S, Gygi SP, Olson G, Aebersold R, et al. (2001) A role for poly(ADP-ribose) polymerase in the transcriptional regulation of the melanoma growth stimulatory activity (CXCL1) gene expression. J Biol Chem 276: 9366-9374.
-
(2001)
J Biol Chem
, vol.276
, pp. 9366-9374
-
-
Nirodi, C.1
NagDas, S.2
Gygi, S.P.3
Olson, G.4
Aebersold, R.5
-
28
-
-
20144389926
-
PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator
-
Pavri R, Lewis B, Kim TK, Dilworth FJ, Erdjument-Bromage H, et al. (2005) PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator. Mol Cell 18: 83-96.
-
(2005)
Mol Cell
, vol.18
, pp. 83-96
-
-
Pavri, R.1
Lewis, B.2
Kim, T.K.3
Dilworth, F.J.4
Erdjument-Bromage, H.5
-
29
-
-
0038682011
-
PARP goes transcription
-
Kraus WL, Lis JT, (2003) PARP goes transcription. Cell 113: 677-683.
-
(2003)
Cell
, vol.113
, pp. 677-683
-
-
Kraus, W.L.1
Lis, J.T.2
-
30
-
-
0035871879
-
Identification of novel functional regions important for the activity of HOXB7 in mammalian cells
-
Yaron Y, McAdara JK, Lynch M, Hughes E, Gasson JC, (2001) Identification of novel functional regions important for the activity of HOXB7 in mammalian cells. J Immunol 166: 5058-5067.
-
(2001)
J Immunol
, vol.166
, pp. 5058-5067
-
-
Yaron, Y.1
McAdara, J.K.2
Lynch, M.3
Hughes, E.4
Gasson, J.C.5
-
31
-
-
33747885367
-
The poly(ADP-ribose) polymerase 1 interacts with Sry and modulates its biological functions
-
Li Y, Oh HJ, Lau YF, (2006) The poly(ADP-ribose) polymerase 1 interacts with Sry and modulates its biological functions. Mol Cell Endocrinol 257-258: 35-46.
-
(2006)
Mol Cell Endocrinol
, vol.257-258
, pp. 35-46
-
-
Li, Y.1
Oh, H.J.2
Lau, Y.F.3
-
32
-
-
21444458209
-
Identification of transcriptional targets of HOXA5
-
Chen H, Rubin E, Zhang H, Chung S, Jie CC, et al. (2005) Identification of transcriptional targets of HOXA5. J Biol Chem 280: 19373-19380.
-
(2005)
J Biol Chem
, vol.280
, pp. 19373-19380
-
-
Chen, H.1
Rubin, E.2
Zhang, H.3
Chung, S.4
Jie, C.C.5
-
33
-
-
0028852624
-
Role of glutamic acid 988 of human poly-ADP-ribose polymerase in polymer formation. Evidence for active site similarities to the ADP-ribosylating toxins
-
Marsischky GT, Wilson BA, Collier RJ, (1995) Role of glutamic acid 988 of human poly-ADP-ribose polymerase in polymer formation. Evidence for active site similarities to the ADP-ribosylating toxins. J Biol Chem 270: 3247-3254.
-
(1995)
J Biol Chem
, vol.270
, pp. 3247-3254
-
-
Marsischky, G.T.1
Wilson, B.A.2
Collier, R.J.3
-
34
-
-
1542682335
-
HOX genes: emerging stars in cancer
-
Chen H, Sukumar S, (2003) HOX genes: emerging stars in cancer. Cancer Biol Ther 2: 524-525.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 524-525
-
-
Chen, H.1
Sukumar, S.2
-
35
-
-
33846362869
-
DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation
-
Cohen-Armon M, Visochek L, Rozensal D, Kalal A, Geistrikh I, et al. (2007) DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation. Molecular cell 25: 297-308.
-
(2007)
Molecular Cell
, vol.25
, pp. 297-308
-
-
Cohen-Armon, M.1
Visochek, L.2
Rozensal, D.3
Kalal, A.4
Geistrikh, I.5
-
36
-
-
0033604898
-
IkappaB-alpha enhances transactivation by the HOXB7 homeodomain-containing protein
-
Chariot A, Princen F, Gielen J, Merville MP, Franzoso G, et al. (1999) IkappaB-alpha enhances transactivation by the HOXB7 homeodomain-containing protein. J Biol Chem 274: 5318-5325.
-
(1999)
J Biol Chem
, vol.274
, pp. 5318-5325
-
-
Chariot, A.1
Princen, F.2
Gielen, J.3
Merville, M.P.4
Franzoso, G.5
-
37
-
-
0033536244
-
CBP and histone deacetylase inhibition enhance the transactivation potential of the HOXB7 homeodomain-containing protein
-
Chariot A, van Lint C, Chapelier M, Gielen J, Merville MP, et al. (1999) CBP and histone deacetylase inhibition enhance the transactivation potential of the HOXB7 homeodomain-containing protein. Oncogene 18: 4007-4014.
-
(1999)
Oncogene
, vol.18
, pp. 4007-4014
-
-
Chariot, A.1
van Lint, C.2
Chapelier, M.3
Gielen, J.4
Merville, M.P.5
-
38
-
-
0029118224
-
The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1
-
Knoepfler PS, Kamps MP, (1995) The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1. Mol Cell Biol 15: 5811-5819.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5811-5819
-
-
Knoepfler, P.S.1
Kamps, M.P.2
-
39
-
-
0346122893
-
PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase
-
Simbulan-Rosenthal CM, Rosenthal DS, Luo R, Samara R, Espinoza LA, et al. (2003) PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase. Oncogene 22: 8460-8471.
-
(2003)
Oncogene
, vol.22
, pp. 8460-8471
-
-
Simbulan-Rosenthal, C.M.1
Rosenthal, D.S.2
Luo, R.3
Samara, R.4
Espinoza, L.A.5
-
40
-
-
0028947525
-
Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins
-
Chang CP, Shen WF, Rozenfeld S, Lawrence HJ, Largman C, et al. (1995) Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. Genes & development 9: 663-674.
-
(1995)
Genes & Development
, vol.9
, pp. 663-674
-
-
Chang, C.P.1
Shen, W.F.2
Rozenfeld, S.3
Lawrence, H.J.4
Largman, C.5
-
41
-
-
0024465662
-
The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16
-
Stern S, Tanaka M, Herr W, (1989) The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16. Nature 341: 624-630.
-
(1989)
Nature
, vol.341
, pp. 624-630
-
-
Stern, S.1
Tanaka, M.2
Herr, W.3
-
42
-
-
34248175954
-
Functional interaction between the transcription factor Kruppel-like factor 5 and poly(ADP-ribose) polymerase-1 in cardiovascular apoptosis
-
Suzuki T, Nishi T, Nagino T, Sasaki K, Aizawa K, et al. (2007) Functional interaction between the transcription factor Kruppel-like factor 5 and poly(ADP-ribose) polymerase-1 in cardiovascular apoptosis. J Biol Chem 282: 9895-9901.
-
(2007)
J Biol Chem
, vol.282
, pp. 9895-9901
-
-
Suzuki, T.1
Nishi, T.2
Nagino, T.3
Sasaki, K.4
Aizawa, K.5
-
43
-
-
4344625329
-
Dual regulation of AP-2alpha transcriptional activation by poly(ADP-ribose) polymerase-1
-
Li M, Naidu P, Yu Y, Berger NA, Kannan P, (2004) Dual regulation of AP-2alpha transcriptional activation by poly(ADP-ribose) polymerase-1. Biochem J 382: 323-329.
-
(2004)
Biochem J
, vol.382
, pp. 323-329
-
-
Li, M.1
Naidu, P.2
Yu, Y.3
Berger, N.A.4
Kannan, P.5
-
44
-
-
0037470044
-
Human growth hormone-regulated HOXA1 is a human mammary epithelial oncogene
-
Zhang X, Zhu T, Chen Y, Mertani HC, Lee KO, et al. (2003) Human growth hormone-regulated HOXA1 is a human mammary epithelial oncogene. J Biol Chem 278: 7580-7590.
-
(2003)
J Biol Chem
, vol.278
, pp. 7580-7590
-
-
Zhang, X.1
Zhu, T.2
Chen, Y.3
Mertani, H.C.4
Lee, K.O.5
-
45
-
-
0037022627
-
Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia
-
Ha HC, Hester LD, Snyder SH, (2002) Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia. Proc Natl Acad Sci U S A 99: 3270-3275.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3270-3275
-
-
Ha, H.C.1
Hester, L.D.2
Snyder, S.H.3
-
46
-
-
34250203586
-
Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation
-
Zhang S, Fei T, Zhang L, Zhang R, Chen F, et al. (2007) Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation. Mol Cell Biol 27: 4488-4499.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4488-4499
-
-
Zhang, S.1
Fei, T.2
Zhang, L.3
Zhang, R.4
Chen, F.5
|