Heterodimerization of Hox proteins with Pbx1 and oncoprotein E2a-Pbx1 generates unique DNA-binding specificities at nucleotides predicted to contact the N-terminal arm of the Hox homeodomain- demonstration of Hox-dependent targeting of E2a-Pbx1 in vivo

Oncogene

Volumn 14, Issue 1, 1997, Pages 75-83

  Lu, Qiang ^a   Kamps, Mark P ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

E2a pbx1; Homeodomain; Hox; Oncoprotein

Indexed keywords

DNA; DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; MUTANT PROTEIN; NUCLEOTIDE; ONCOPROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIMERIZATION; DNA SEQUENCE; GENE TARGETING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION;

EID: 0031019639     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1200799     Document Type: Article

References (39)

1. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA and Struhl K. (1989). Current Protocols in Molecular Biology, 1, 8.1.1-8.1.6.
2. Carroll A, Crist W, Parmley R, Roper M, Cooper M and Finley W. (1984). Blood, 63, 721-724.
3. Chan SK, Jaffe L, Capovilla M, Botas J and Mann R. (1994). Cell, 78, 603-615.
4. Chan SK and Mann RS. (1996). Proc. Natl. Acad. Sci. USA, 93, 5223-5228.
5. Chang CP, Shen WF, Rozenfeld S, Lawrence HJ, Largman C and Cleary ML. (1995). Genes & Dev., 9, 663-674.
6. Dedera DA, Waller EK, Lebrun DP, Sen-Majumbar A, Stevens ME, Barsh GS and Cleary ML. (1993). Cell, 74, 833-843.
7. Furukbo-Tokunaga K, Flister S and Gehring WJ. (1993). Proc. Natl. Acad. Sci. USA, 90, 6360-6364.
8. Gehring WJ, Affolter M and Bürglin T. (1994a). Annu. Rev. Biochem., 63, 487-526.
9. Gehring WJ, Qian YQ, Billeter M, Furukubo-Tokunaga K, Schier AF, Resendcz-perez D, Affolter M, Otting G and Wüthrich K. (1994b). Cell, 78, 211-223.
10. Johnson FB, Parker E and Krasnow MA. (1995). Proc. Natl. Acad. Sci., 92, 739-743.
11. Kamps MP, Murre C, Sun X and Baltimore D. (1991). Cell, 60, 547-555.
12. Kamps MP and Baltimore D. (1993). Mol. Cell. Biol., 13, 351-357.
13. Kamps MP and Wright D. (1994). Oncogene, 9, 3159-3166.
14. Kamps MP, Wright DD and Lu Q. (1996). Oncogene, 12, 19-30.
15. Kissinger CR, Liu BS, Martin-Blabco E, Kornberg TB and Pabo CO. (1990). Cell, 63, 579-590.
16. Knoepfler P and Kamps MP. (1995). Mol. Cell. Biol., 15, 5811-5819.
17. Knoepfler P. Lu Q and Kamps M. (1996). Nuc. Acid. Res., 24, 2288-2294.
18. Krumlauf R. (1994). Cell, 78, 191-201.
19. Kunkel TA, Roberts JD and Zakour RA. (1987). Meth. Enzymol., 154, 367-378.
20. Laughon A. (1991). Biochemistry, 30, 11357-11367.
21. Lawrence H, Stage K, Mathews C, Detmer K, Scibienski R, MacKenzi M, Migliaccio E, Boncinelli E and Largmen C. (1993). Cell Growth and Differentiation, 4, 665-669.
22. Lebrun DP and Cleary ML. (1994). Oncogene, 9, 1641-1647.
23. Lu Q, Wright DD and Kamps MP. (1994). Mol. Cell. Biol., 6, 3938-3948.
24. Lu Q, Knoepfler P, Scheele J, Wright DD and Kamps MP. (1995). Mol. Cell. Biol., 15, 3786-3795.
25. Lu Q and Kamps MP. (1996). Mol. Cell. Biol., 16, 1632-1640.
26. Mathews C, Detmer K, Boncinelli E, Lawrence H and Largmen C. (1991). Blood, 78, 2248-2252.
27. McGinnis N, Kuziora M and McGinnis W. (1990). Cell, 63, 969-976.
28. Monica K, Galili N, Nourse J, Saltman D and Cleary ML. (1991). Mol. Cell. Biol., 11, 6149-6157.
29. Neuteboom STC, Peltenburg LTC, Van Dijk MA and Murre C. (1995). Proc. Natl. Acad. Sci. USA, 92, 9166-9170.
30. Nourse J, Mellentin JD, Galili N, Wilkinson J, Stanbridge E, Smith SD and Cleary ML. (1990). Cell, 60, 535-545.
31. Peers B, Sharma S, Johnson T, Kamps MP and Montminy M. (1995). Mol. Cell. Biol., 15, 7091-7097.
32. Petrini M, Quaranta M, Testa U, Samoggia P, Tritarelli E, Care A, Cianetti L, Valtieri M, Barletta C and Peschle C. (1992). Blood, 80, 185-193.
33. Pöpperl H, Bienz M, Studer M, Chan SK, Aparicio S, Brenner S, Mann RS and Krumlauf R. (1995). Cell, 81, 1031-1042.
34. Pöpperl H and Featherstone M. (1992). EMBO J., 11, 3673-3680.
35. Regulski M, Dessain S, McGinnis N and McGinnis W. (1991). Genes & Dev., 5, 278-286.
36. Van Dijk MA, Voorhoeve P and Murre C. (1993). Proc. Natl. Acad. Sci. USA, 90, 6061-6065.
37. Van Dijk MA and Murre C. (1994). Cell, 78, 617-624.
38. Vieille-Grosjean I, Roullot V and Courtois G. (1992). BBRC, 183, 1124-1130.
39. Zeng W, Andrew DJ, Mathies LD, Horner MA and Scott MP. (1993). Development, 118, 339-352.