TRPA1 Mediates Mechanical currents in the plasma membrane of Mouse Sensory Neurons

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Vilceanu, Daniel ^a   Stucky, Cheryl L ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HC 030031; ISOLECTIN B4; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; TRANSIENT RECEPTOR POTENTIAL CHANNEL AFFECTING AGENT; UNCLASSIFIED DRUG; ANKTM1 PROTEIN, MOUSE; LECTIN; TRANSIENT RECEPTOR POTENTIAL CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CELL SIZE; CELL STRAIN HEK293; CONTROLLED STUDY; ELECTRIC CAPACITANCE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MALE; MECHANICAL STIMULATION; MECHANOTRANSDUCTION; MOUSE; NERVE CELL CULTURE; NERVE CELL MEMBRANE; NERVE CELL MEMBRANE STEADY POTENTIAL; NONHUMAN; PROTEIN BINDING; SENSORY NERVE CELL; SLOW INWARD CURRENT; SPINAL GANGLION; WILD TYPE; ADAPTATION; ANIMAL; BIOMECHANICS; CELL LINE; CELL MEMBRANE; CYTOLOGY; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; SENSORY RECEPTOR; TIME;

MUS;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BIOMECHANICS; CELL LINE; CELL MEMBRANE; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; LECTINS; MALE; MICE; SENSORY RECEPTOR CELLS; TIME FACTORS; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 77957860650     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012177     Document Type: Article

References (31)

1. Stokes NR, Murray HD, Subramaniam C, Gourse RL, Louis P, et al. (2003) A role for mechanosensitive channels in survival of stationary phase: regulation of channel expression by RpoS. Proc Natl Acad Sci U S A 100: 15959-15964.
2. Martinac B, Saimi Y, Kung C (2008) Ion channels in microbes. Physiol Rev 88: 1449-1490.
3. Anishkin A, Kung C (2005) Microbial mechanosensation. Curr Opin Neurobiol 15: 397-405.
4. Chalfie M (2009) Neurosensory mechanotransduction. Nat Rev Mol Cell Biol 10: 44-52.
5. Inoue R, Jian Z, Kawarabayashi Y (2009) Mechanosensitive TRP channels in cardiovascular pathophysiology. Pharmacol Ther 123: 371-385.
6. Christensen AP, Corey DP (2007) TRP channels in mechanosensation: direct or indirect activation? Nat Rev Neurosci 8: 510-521.
7. Drew LJ, Wood JN, Cesare P (2002) Distinct mechanosensitive properties of capsaicin-sensitive and -insensitive sensory neurons. J Neurosci 22: RC228.
8. Hu J, Lewin GR (2006) Mechanosensitive currents in the neurites of cultured mouse sensory neurones. J Physiol 577: 815-828.
9. Jaquemar D, Schenker T, Trueb B (1999) An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts. J Biol Chem 274: 7325-7333.
10. Story GM, Peier AM, Reeve AJ, Eid SR, Mosbacher J, et al. (2003) ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112: 819-829.
11. Corey DP, Garcia-Anoveros J, Holt JR, Kwan KY, Lin SY, et al. (2004) TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells. Nature 432: 723-730.
12. Sotomayor M, Corey DP, Schulten K (2005) In search of the hair-cell gating spring elastic properties of ankyrin and cadherin repeats. Structure 13: 669-682.
13. Kwan KY, Allchorne AJ, Vollrath MA, Christensen AP, Zhang DS, et al. (2006) TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction. Neuron 50: 277-289.
14. Kwan KY, Glazer JM, Corey DP, Rice FL, Stucky CL (2009) TRPA1 modulates mechanotransduction in cutaneous sensory neurons. J Neurosci 29: 4808-4819.
15. McNamara CR, Mandel-Brehm J, Bautista DM, Siemens J, Deranian KL, et al. (2007) TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci U S A 104: 13525-13530.
16. Kerstein PC, del Camino D, Moran MM, Stucky CL (2009) Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors. Mol Pain 5: 19.
17. Anand U, Otto WR, Facer P, Zebda N, Selmer I, et al. (2008) TRPA1 receptor localisation in the human peripheral nervous system and functional studies in cultured human and rat sensory neurons. Neurosci Lett 438: 221-227.
18. Atoyan R, Shander D, Botchkareva NV (2009) Non-neuronal expression of transient receptor potential type A1 (TRPA1) in human skin. J Invest Dermatol 129: 2312-2315.
19. McCarter GC, Reichling DB, Levine JD (1999) Mechanical transduction by rat dorsal root ganglion neurons in vitro. Neurosci Lett 273: 179-182.
20. Jordt SE, Bautista DM, Chuang HH, McKemy DD, Zygmunt PM, et al. (2004) Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427: 260-265.
21. Dirajlal S, Pauers LE, Stucky CL (2003) Differential response properties of IB(4)-positive and -negative unmyelinated sensory neurons to protons and capsaicin. J Neurophysiol 89: 513-524.
22. Stucky CL, Lewin GR (1999) Isolectin B(4)-positive and -negative nociceptors are functionally distinct. J Neurosci 19: 6497-6505.
23. Lechner SG, Frenzel H, Wang R, Lewin GR (2009) Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development. EMBO J 28: 1479-1491.
24. McCarter GC, Levine JD (2006) Ionic basis of a mechanotransduction current in adult rat dorsal root ganglion neurons. Mol Pain 2: 28.
25. Vilceanu D, Honore P, Hogan QH, Stucky CL (2010) Spinal nerve ligation in mouse upregulates TRPV1 heat function in injured IB4-positive nociceptors. J Pain 11: 588-599.
26. Tsunozaki M, Bautista DM (2009) Mammalian somatosensory mechanotransduction. Curr Opin Neurobiol 19: 362-369.
27. Rugiero F, Wood JN (2009) The mechanosensitive cell line ND-C does not express functional thermoTRP channels. Neuropharmacology 56: 1138-1146.
28. Akopian AN, Ruparel NB, Jeske NA, Hargreaves KM (2007) Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1-irected internalization. J Physiol 583: 175-193.
29. Salas MM, Hargreaves KM, Akopian AN (2009) TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1. Eur J Neurosci 29: 1568-1578.
30. Zurborg S, Yurgionas B, Jira JA, Caspani O, Heppenstall PA (2007) Direct activation of the ion channel TRPA1 by Ca2+. Nat Neurosci 10: 277-279.
31. Doerner JF, Gisselmann G, Hatt H, Wetzel CH (2007) Transient receptor potential channel A1 is directly gated by calcium ions. J Biol Chem 282: 13180-13189.