메뉴 건너뛰기




Volumn 50, Issue 29, 2011, Pages 6295-6300

The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR LEVELS; CURRENT KINETICS; DIAGNOSTIC ASSAYS; DISSOCIATION RATES; EXTRACELLULAR; HEK293 CELLS; HIGH-THROUGHPUT; MECHANICAL STRESS; MECHANOSENSITIVE ION CHANNELS; MECHANOSENSITIVITY; MICROMOLAR CONCENTRATION; MIRROR IMAGES; OPEN CHANNELS; PHARMACOLOGICAL AGENTS;

EID: 79960498823     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200770q     Document Type: Article
Times cited : (354)

References (31)
  • 2
    • 0021287115 scopus 로고
    • Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle
    • Guharay, F. and Sachs, F. (1984) Stretch-activated single ion channel currents in tissue-cultured embryonic chick skeletal muscle J. Physiol. 352, 685-701 (Pubitemid 14059646)
    • (1984) Journal of Physiology , vol.352 , pp. 685-701
    • Guharay, F.1    Sachs, F.2
  • 3
    • 0034103610 scopus 로고    scopus 로고
    • Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels
    • DOI 10.1085/jgp.115.5.583
    • Suchyna, T. M., Johnson, J. H., Hamer, K., Leykam, J. F., Gage, D. A., Clemo, H. F., Baumgarten, C. M., and Sachs, F. (2000) Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels J. Gen. Physiol. 115, 583-598 (Pubitemid 30249974)
    • (2000) Journal of General Physiology , vol.115 , Issue.5 , pp. 583-598
    • Suchyna, T.M.1    Johnson, J.H.2    Hamer, K.3    Leykam, J.F.4    Gage, D.A.5    Clemo, H.F.6    Baumgarten, C.M.7    Sachs, F.8
  • 5
    • 5644275478 scopus 로고    scopus 로고
    • 2P channels and their role in general anaesthesia and neuroprotection
    • DOI 10.1016/j.tips.2004.09.003, PII S0165614704002536
    • Franks, N. P. and Honore, E. (2004) The TREK K2P channels and their role in general anaesthesia and neuroprotection Trends Pharmacol. Sci. 25, 601-608 (Pubitemid 39371151)
    • (2004) Trends in Pharmacological Sciences , vol.25 , Issue.11 , pp. 601-608
    • Franks, N.P.1    Honore, E.2
  • 7
    • 33747785243 scopus 로고    scopus 로고
    • A novel membrane protein, encoded by the gene covering KIAA0233, is transcriptionally induced in senile plaque-associated astrocytes
    • DOI 10.1016/j.brainres.2006.06.050, PII S0006899306018002
    • Satoh, K., Hata, M., Takahara, S., Tsuzaki, H., Yokota, H., Akatsu, H., Yamamoto, T., Kosaka, K., and Yamada, T. (2006) A novel membrane protein, encoded by the gene covering KIAA0233, is transcriptionally induced in senile plaque-associated astrocytes Brain Res. 1108, 19-27 (Pubitemid 44278021)
    • (2006) Brain Research , vol.1108 , Issue.1 , pp. 19-27
    • Satoh, K.1    Hata, M.2    Takahara, S.3    Tsuzaki, H.4    Yokota, H.5    Akatsu, H.6    Yamamoto, T.7    Kosaka, K.8    Yamada, T.9
  • 8
    • 72449161735 scopus 로고    scopus 로고
    • Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum
    • McHugh, B. J., Buttery, R., Lad, Y., Banks, S., Haslett, C., and Sethi, T. (2010) Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum J. Cell Sci. 123, 51-61
    • (2010) J. Cell Sci. , vol.123 , pp. 51-61
    • McHugh, B.J.1    Buttery, R.2    Lad, Y.3    Banks, S.4    Haslett, C.5    Sethi, T.6
  • 9
    • 34147177561 scopus 로고    scopus 로고
    • Properties and Mechanism of the Mechanosensitive Ion Channel Inhibitor GsMTx4, a Therapeutic Peptide Derived from Tarantula Venom
    • In (Hamill, O., Ed.) pp, Academic Press, New York
    • Gottlieb, P., Suchyna, T., and Sachs, F. (2006) Properties and Mechanism of the Mechanosensitive Ion Channel Inhibitor GsMTx4, a Therapeutic Peptide Derived from Tarantula Venom. In Current Topics in Membranes and Transport (Hamill, O., Ed.) pp 81-109, Academic Press, New York.
    • (2006) Current Topics in Membranes and Transport , pp. 81-109
    • Gottlieb, P.1    Suchyna, T.2    Sachs, F.3
  • 10
    • 33846426807 scopus 로고    scopus 로고
    • Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: History, properties, mechanisms and pharmacology
    • DOI 10.1016/j.toxicon.2006.09.030, PII S0041010106003564
    • Bowman, C. L., Gottlieb, P. A., Suchyna, T. M., Murphy, Y. K., and Sachs, F. (2007) Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: History, properties, mechanisms and pharmacology Toxicon 49, 249-270 (Pubitemid 46148998)
    • (2007) Toxicon , vol.49 , Issue.2 , pp. 249-270
    • Bowman, C.L.1    Gottlieb, P.A.2    Suchyna, T.M.3    Murphy, Y.K.4    Sachs, F.5
  • 11
    • 0037072815 scopus 로고    scopus 로고
    • Solution structure of peptide toxins that block mechanosensitive ion channels
    • Oswald, R. E., Suchyna, T. M., McFeeters, R., Gottlieb, P., and Sachs, F. (2002) Solution structure of peptide toxins that block mechanosensitive ion channels J. Biol. Chem. 277, 34443-34450
    • (2002) J. Biol. Chem. , vol.277 , pp. 34443-34450
    • Oswald, R.E.1    Suchyna, T.M.2    McFeeters, R.3    Gottlieb, P.4    Sachs, F.5
  • 12
    • 3142652571 scopus 로고    scopus 로고
    • Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers
    • DOI 10.1038/nature02743
    • Suchyna, T. M., Tape, S. E., Koeppe, R. E., II, Andersen, O. S., Sachs, F., and Gottlieb, P. A. (2004) Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers Nature 430, 235-240 (Pubitemid 38902435)
    • (2004) Nature , vol.430 , Issue.6996 , pp. 235-240
    • Suchyna, T.M.1    Tape, S.E.2    Koeppe II, R.E.3    Andersen, O.S.4    Sachs, F.5    Gottlieb, P.A.6
  • 13
    • 0242349155 scopus 로고    scopus 로고
    • CDNA sequence and in vitro folding of GsMTx4, a specific peptide inhibitor of mechanosensitive channels
    • DOI 10.1016/S0041-0101(03)00141-7
    • Ostrow, K. L., Mammoser, A., Suchyna, T., Sachs, F., Oswald, R., Kubo, S., Chino, N., and Gottlieb, P. A. (2003) cDNA sequence and in vitro folding of GsMTx4, a specific peptide inhibitor of mechanosensitive channels Toxicon 42, 263-274 (Pubitemid 37338163)
    • (2003) Toxicon , vol.42 , Issue.3 , pp. 263-274
    • Ostrow, K.L.1    Mammoser, A.2    Suchyna, T.3    Sachs, F.4    Oswald, R.5    Kubo, S.6    Chino, N.7    Gottlieb, P.A.8
  • 15
    • 77952611737 scopus 로고    scopus 로고
    • A mechanosensitive ion channel regulating cell volume
    • Hua, S. Z., Gottlieb, P. A., Heo, J., and Sachs, F. (2010) A mechanosensitive ion channel regulating cell volume Am. J. Physiol. 298, C1424-C1430
    • (2010) Am. J. Physiol. , vol.298
    • Hua, S.Z.1    Gottlieb, P.A.2    Heo, J.3    Sachs, F.4
  • 16
    • 0035804258 scopus 로고    scopus 로고
    • Tarantula peptide inhibits atrial fibrillation
    • DOI 10.1038/35051165
    • Bode, F., Sachs, F., and Franz, M. R. (2001) Tarantula Peptide Inhibits Atrial Fibrillation During Stretch Nature 409, 35-36 (Pubitemid 32098613)
    • (2001) Nature , vol.409 , Issue.6816 , pp. 35-36
    • Bode, F.1    Sachs, F.2    Franz, M.R.3
  • 17
    • 68849117075 scopus 로고    scopus 로고
    • Biophysics and structure of the patch and the gigaseal
    • Suchyna, T. M., Markin, V. S., and Sachs, F. (2009) Biophysics and structure of the patch and the gigaseal Biophys. J. 97, 738-747
    • (2009) Biophys. J. , vol.97 , pp. 738-747
    • Suchyna, T.M.1    Markin, V.S.2    Sachs, F.3
  • 19
    • 0030013925 scopus 로고    scopus 로고
    • The pharmacology of mechanogated membrane ion channels
    • Hamill, O. P. and McBride, D. W., Jr. (1996) The pharmacology of mechanogated membrane ion channels Pharmacol. Rev. 48, 231-252 (Pubitemid 26196587)
    • (1996) Pharmacological Reviews , vol.48 , Issue.2 , pp. 231-252
    • Hamill, O.P.1    Mcbride Jr., D.W.2
  • 20
    • 17844405808 scopus 로고    scopus 로고
    • Maximum likelihood estimation of ion channel kinetics from macroscopic currents
    • DOI 10.1529/biophysj.104.053256
    • Milescu, L. S., Akk, G., and Sachs, F. (2005) Maximum likelihood estimation of ion channel kinetics from macroscopic currents Biophys. J. 88, 2494-2515 (Pubitemid 40976119)
    • (2005) Biophysical Journal , vol.88 , Issue.4 , pp. 2494-2515
    • Milescu, L.S.1    Akk, G.2    Sachs, F.3
  • 21
    • 85040875608 scopus 로고
    • Cambridge University Press, Cambridge, U.K
    • Johnson, K. L. (1985) Contact mechanics, Cambridge University Press, Cambridge, U.K.
    • (1985) Contact Mechanics
    • Johnson, K.L.1
  • 22
  • 23
    • 78349242176 scopus 로고    scopus 로고
    • Effects of GsMTx4 on bacterial mechanosensitive channels in inside-out patches from giant spheroplasts
    • Kamaraju, K., Gottlieb, P. A., Sachs, F., and Sukharev, S. (2010) Effects of GsMTx4 on bacterial mechanosensitive channels in inside-out patches from giant spheroplasts Biophys. J. 99, 2870-2878
    • (2010) Biophys. J. , vol.99 , pp. 2870-2878
    • Kamaraju, K.1    Gottlieb, P.A.2    Sachs, F.3    Sukharev, S.4
  • 24
    • 4544280751 scopus 로고    scopus 로고
    • Thermodynamics of mechanosensitivity
    • DOI 10.1088/1478-3967/1/2/007, PII S1478396704811434, 007
    • Markin, V. S. and Sachs, F. (2004) Thermodynamics of mechanosensitivity Phys. Biol. 1, 110-124 (Pubitemid 44362307)
    • (2004) Physical Biology , vol.1 , Issue.2 , pp. 110-124
    • Markin, V.S.1    Sachs, F.2
  • 25
    • 34248172959 scopus 로고    scopus 로고
    • Mechanosensitive channel properties and membrane mechanics in mouse dystrophic myotubes
    • DOI 10.1113/jphysiol.2006.125021
    • Suchyna, T. M. and Sachs, F. (2007) Mechanosensitive channel properties and membrane mechanics in mouse dystrophic myotubes J. Physiol. 581, 369-387 (Pubitemid 46712046)
    • (2007) Journal of Physiology , vol.581 , Issue.1 , pp. 369-387
    • Suchyna, T.M.1    Sachs, F.2
  • 26
    • 0032171587 scopus 로고    scopus 로고
    • Membrane tension in swelling and shrinking molluscan neurons
    • Dai, J., Sheetz, M. P., Wan, X., and Morris, C. E. (1998) Membrane tension in swelling and shrinking molluscan neurons J. Neurosci. 18, 6681-6692 (Pubitemid 28388000)
    • (1998) Journal of Neuroscience , vol.18 , Issue.17 , pp. 6681-6692
    • Dai, J.1    Sheetz, M.P.2    Wan, X.3    Morris, C.E.4
  • 27
    • 0025837411 scopus 로고
    • Mechanosensitive ion channels as reporters of bilayer expansion. A theoretical model
    • Markin, V. S. and Martinac, B. (1991) Mechanosensitive ion channels as reporters of bilayer expansion. A theoretical model Biophys. J. 60, 1120-1127
    • (1991) Biophys. J. , vol.60 , pp. 1120-1127
    • Markin, V.S.1    Martinac, B.2
  • 28
    • 34548214197 scopus 로고    scopus 로고
    • Is lipid bilayer binding a common property of inhibitor cysteine knot ion-channel blockers?
    • Posokhov, Y. O., Gottlieb, P. A., Morales, M. J., Sachs, F., and Ladokhin, A. S. (2007) Is lipid bilayer binding a common property of inhibitor cysteine knot ion-channel blockers? Biophys. J. 93, L20-L22
    • (2007) Biophys. J. , vol.93
    • Posokhov, Y.O.1    Gottlieb, P.A.2    Morales, M.J.3    Sachs, F.4    Ladokhin, A.S.5
  • 29
    • 33846863603 scopus 로고    scopus 로고
    • Quenching-enhanced fluorescence titration protocol for accurate determination of free energy of membrane binding
    • DOI 10.1016/j.ab.2006.11.022, PII S0003269706008451
    • Posokhov, Y. O., Gottlieb, P. A., and Ladokhin, A. S. (2007) Quenching-enhanced fluorescence titration protocol for accurate determination of free energy of membrane binding Anal. Biochem. 362, 290-292 (Pubitemid 46227311)
    • (2007) Analytical Biochemistry , vol.362 , Issue.2 , pp. 290-292
    • Posokhov, Y.O.1    Gottlieb, P.A.2    Ladokhin, A.S.3
  • 30
    • 0032568955 scopus 로고    scopus 로고
    • Isolation and characterization of monomeric and dimeric CP47-reaction center photosystem II complexes
    • DOI 10.1074/jbc.273.26.16122
    • Zheleva, D., Sharma, J., Panico, M., Morris, H. R., and Barber, J. (1998) Isolation and characterization of monomeric and dimeric CP47-reaction center photosystem II complexes J. Biol. Chem. 273, 16122-16127 (Pubitemid 28311382)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.26 , pp. 16122-16127
    • Zheleva, D.1    Sharma, J.2    Panico, M.3    Morris, H.R.4    Barber, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.