메뉴 건너뛰기




Volumn 7, Issue 7, 2012, Pages

P53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiation

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN 14; PHORBOL 13 ACETATE 12 MYRISTATE; PIFITHRIN ALPHA; PROTEIN P160; PROTEIN P53; TRANSCRIPTION FACTOR SP1;

EID: 84864199929     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041742     Document Type: Article
Times cited : (22)

References (64)
  • 2
    • 0031310665 scopus 로고    scopus 로고
    • 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression
    • Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, et al. (1997) 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Mol Cell 1: 3-11.
    • (1997) Mol Cell , vol.1 , pp. 3-11
    • Hermeking, H.1    Lengauer, C.2    Polyak, K.3    He, T.C.4    Zhang, L.5
  • 3
    • 0037377761 scopus 로고    scopus 로고
    • The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
    • Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA, (2003) The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol Cell Biol 23: 2264-2276.
    • (2003) Mol Cell Biol , vol.23 , pp. 2264-2276
    • Westfall, M.D.1    Mays, D.J.2    Sniezek, J.C.3    Pietenpol, J.A.4
  • 4
    • 38349046731 scopus 로고    scopus 로고
    • TAp63-dependent induction of growth differentiation factor 15 (GDF15) plays a critical role in the regulation of keratinocyte differentiation
    • Ichikawa T, Suenaga Y, Koda T, Ozaki T, Nakagawara A, (2008) TAp63-dependent induction of growth differentiation factor 15 (GDF15) plays a critical role in the regulation of keratinocyte differentiation. Oncogene 27: 409-420.
    • (2008) Oncogene , vol.27 , pp. 409-420
    • Ichikawa, T.1    Suenaga, Y.2    Koda, T.3    Ozaki, T.4    Nakagawara, A.5
  • 5
    • 70350674206 scopus 로고    scopus 로고
    • Identification and functional characterization of two new transcriptional variants of the human p63 gene
    • Mangiulli M, Valletti A, Caratozzolo MF, Tullo A, Sbisa E, et al. (2009) Identification and functional characterization of two new transcriptional variants of the human p63 gene. Nucleic Acids Res 37: 6092-6104.
    • (2009) Nucleic Acids Res , vol.37 , pp. 6092-6104
    • Mangiulli, M.1    Valletti, A.2    Caratozzolo, M.F.3    Tullo, A.4    Sbisa, E.5
  • 6
    • 0033594491 scopus 로고    scopus 로고
    • p63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, et al. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398: 708-713.
    • (1999) Nature , vol.398 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.J.3    Vogel, H.4    Roop, D.R.5
  • 7
    • 0033594485 scopus 로고    scopus 로고
    • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, et al. (1999) p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 398: 714-718.
    • (1999) Nature , vol.398 , pp. 714-718
    • Yang, A.1    Schweitzer, R.2    Sun, D.3    Kaghad, M.4    Walker, N.5
  • 9
    • 0034576495 scopus 로고    scopus 로고
    • P63 and P73: P53 mimics, menaces and more
    • Yang A, McKeon F, (2000) P63 and P73: P53 mimics, menaces and more. Nat Rev Mol Cell Biol 1: 199-207.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 199-207
    • Yang, A.1    McKeon, F.2
  • 10
    • 0032161624 scopus 로고    scopus 로고
    • p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, et al. (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 2: 305-316.
    • (1998) Mol Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5
  • 11
    • 0030935565 scopus 로고    scopus 로고
    • The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation
    • Eckert RL, Crish JF, Robinson NA, (1997) The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation. Phys Rev 77: 397-424.
    • (1997) Phys Rev , vol.77 , pp. 397-424
    • Eckert, R.L.1    Crish, J.F.2    Robinson, N.A.3
  • 12
    • 29144524913 scopus 로고    scopus 로고
    • TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis
    • Koster MI, Kim S, Huang J, Williams T, Roop DR, (2006) TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis. Dev Biol 289: 253-261.
    • (2006) Dev Biol , vol.289 , pp. 253-261
    • Koster, M.I.1    Kim, S.2    Huang, J.3    Williams, T.4    Roop, D.R.5
  • 13
    • 33646797744 scopus 로고    scopus 로고
    • Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice
    • Candi E, Rufini A, Terrinoni A, Dinsdale D, Ranalli M, et al. (2006) Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice. Cell Death Differ 13: 1037-1047.
    • (2006) Cell Death Differ , vol.13 , pp. 1037-1047
    • Candi, E.1    Rufini, A.2    Terrinoni, A.3    Dinsdale, D.4    Ranalli, M.5
  • 14
    • 66049096917 scopus 로고    scopus 로고
    • An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate
    • Romano RA, Ortt K, Birkaya B, Smalley K, Sinha S, (2009) An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate. PLoS One 4: e5623.
    • (2009) PLoS One , vol.4
    • Romano, R.A.1    Ortt, K.2    Birkaya, B.3    Smalley, K.4    Sinha, S.5
  • 15
    • 84863676587 scopus 로고    scopus 로고
    • A half-site of the p53 binding site on the keratin 14 promoter is specifically activated by p63
    • doi:10.1093/jb/mvs053
    • Cai BH, Chao CF, Lu MH, Lin HC, Chen JY, (2012) A half-site of the p53 binding site on the keratin 14 promoter is specifically activated by p63. J Biochem doi:10.1093/jb/mvs053.
    • (2012) J Biochem
    • Cai, B.H.1    Chao, C.F.2    Lu, M.H.3    Lin, H.C.4    Chen, J.Y.5
  • 16
    • 52149090309 scopus 로고    scopus 로고
    • A method for quantifying melanosome transfer efficacy from melanocytes to keratinocytes in vitro
    • Lin HC, Shieh BH, Lu MH, Chen JY, Chang LT, et al. (2008) A method for quantifying melanosome transfer efficacy from melanocytes to keratinocytes in vitro. Pigment Cell Melanoma Res 21: 559-564.
    • (2008) Pigment Cell Melanoma Res , vol.21 , pp. 559-564
    • Lin, H.C.1    Shieh, B.H.2    Lu, M.H.3    Chen, J.Y.4    Chang, L.T.5
  • 17
    • 0034302907 scopus 로고    scopus 로고
    • Temporal and spatial sequence expression of cytokeratin K19 in cultured human keratinocyte
    • Lu MH, Yang PC, Chang LT, Chao CF, (2000) Temporal and spatial sequence expression of cytokeratin K19 in cultured human keratinocyte. Proc Natl Sci Counc Repub China B 24: 169-177.
    • (2000) Proc Natl Sci Counc Repub China B , vol.24 , pp. 169-177
    • Lu, M.H.1    Yang, P.C.2    Chang, L.T.3    Chao, C.F.4
  • 18
    • 0023928104 scopus 로고
    • Early signals for keratinocyte differentiation: role of Ca2+-mediated inositol lipid metabolism in normal and neoplastic epidermal cells
    • Jaken S, Yuspa SH, (1988) Early signals for keratinocyte differentiation: role of Ca2+-mediated inositol lipid metabolism in normal and neoplastic epidermal cells. Carcinogenesis 9: 1033-1038.
    • (1988) Carcinogenesis , vol.9 , pp. 1033-1038
    • Jaken, S.1    Yuspa, S.H.2
  • 19
    • 0035884402 scopus 로고    scopus 로고
    • Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in mammary carcinoma
    • Pal S, Datta K, Mukhopadhyay D, (2001) Central role of p53 on regulation of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) expression in mammary carcinoma. Cancer Res 61: 6952-6957.
    • (2001) Cancer Res , vol.61 , pp. 6952-6957
    • Pal, S.1    Datta, K.2    Mukhopadhyay, D.3
  • 20
    • 13844280115 scopus 로고    scopus 로고
    • p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription
    • Innocente SA, Lee JM, (2005) p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription. FEBS Lett 579: 1001-1007.
    • (2005) FEBS Lett , vol.579 , pp. 1001-1007
    • Innocente, S.A.1    Lee, J.M.2
  • 21
    • 0029909531 scopus 로고    scopus 로고
    • Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein
    • Farmer G, Friedlander P, Colgan J, Manley JL, Prives C, (1996) Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein. Nucleic Acids Res 24: 4281-4288.
    • (1996) Nucleic Acids Res , vol.24 , pp. 4281-4288
    • Farmer, G.1    Friedlander, P.2    Colgan, J.3    Manley, J.L.4    Prives, C.5
  • 22
    • 0035843156 scopus 로고    scopus 로고
    • Negative regulation of bcl-2 expression by p53 in hematopoietic cells
    • Wu Y, Mehew JW, Heckman CA, Arcinas M, Boxer LM, (2001) Negative regulation of bcl-2 expression by p53 in hematopoietic cells. Oncogene 20: 240-251.
    • (2001) Oncogene , vol.20 , pp. 240-251
    • Wu, Y.1    Mehew, J.W.2    Heckman, C.A.3    Arcinas, M.4    Boxer, L.M.5
  • 23
    • 22544441310 scopus 로고    scopus 로고
    • Physical and functional interactions between members of the tumour suppressor p53 and the Sp families of transcription factors: importance for the regulation of genes involved in cell-cycle arrest and apoptosis
    • Koutsodontis G, Vasilaki E, Chou WC, Papakosta P, Kardassis D, (2005) Physical and functional interactions between members of the tumour suppressor p53 and the Sp families of transcription factors: importance for the regulation of genes involved in cell-cycle arrest and apoptosis. Biochem J 389: 443-455.
    • (2005) Biochem J , vol.389 , pp. 443-455
    • Koutsodontis, G.1    Vasilaki, E.2    Chou, W.C.3    Papakosta, P.4    Kardassis, D.5
  • 24
    • 41849146852 scopus 로고    scopus 로고
    • C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity
    • Sauer M, Bretz AC, Beinoraviciute-Kellner R, Beitzinger M, Burek C, et al. (2008) C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity. Nucleic Acids Res 36: 1900-1912.
    • (2008) Nucleic Acids Res , vol.36 , pp. 1900-1912
    • Sauer, M.1    Bretz, A.C.2    Beinoraviciute-Kellner, R.3    Beitzinger, M.4    Burek, C.5
  • 25
    • 64549154804 scopus 로고    scopus 로고
    • Functional four-base A/T gap core sequence CATTAG of P53 response elements specifically bound tetrameric P53 differently than two-base A/T gap core sequence CATG bound both dimeric and tetrameric P53
    • Cai BH, Chen JY, Lu MH, Chang LT, Lin HC, et al. (2009) Functional four-base A/T gap core sequence CATTAG of P53 response elements specifically bound tetrameric P53 differently than two-base A/T gap core sequence CATG bound both dimeric and tetrameric P53. Nucleic Acids Res 37: 1984-1990.
    • (2009) Nucleic Acids Res , vol.37 , pp. 1984-1990
    • Cai, B.H.1    Chen, J.Y.2    Lu, M.H.3    Chang, L.T.4    Lin, H.C.5
  • 26
    • 0023239517 scopus 로고
    • Functional inactivation of genes by dominant negative mutations
    • Herskowitz I, (1987) Functional inactivation of genes by dominant negative mutations. Nature 329: 219-222.
    • (1987) Nature , vol.329 , pp. 219-222
    • Herskowitz, I.1
  • 27
    • 0025731379 scopus 로고
    • Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation
    • Milner J, Medcalf EA, (1991) Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation. Cell 65: 765-774.
    • (1991) Cell , vol.65 , pp. 765-774
    • Milner, J.1    Medcalf, E.A.2
  • 28
    • 1842609721 scopus 로고    scopus 로고
    • How many mutant p53 molecules are needed to inactivate a tetramer?
    • Chan WM, Siu WY, Lau A, Poon RY, (2004) How many mutant p53 molecules are needed to inactivate a tetramer? Mol Cell Biol 24: 3536-3551.
    • (2004) Mol Cell Biol , vol.24 , pp. 3536-3551
    • Chan, W.M.1    Siu, W.Y.2    Lau, A.3    Poon, R.Y.4
  • 29
    • 0033543728 scopus 로고    scopus 로고
    • A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy
    • Komarov PG, Komarova EA, Kondratov RV, Christov-Tselkov K, Coon JS, et al. (1999) A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285: 1733-1737.
    • (1999) Science , vol.285 , pp. 1733-1737
    • Komarov, P.G.1    Komarova, E.A.2    Kondratov, R.V.3    Christov-Tselkov, K.4    Coon, J.S.5
  • 30
    • 0034523382 scopus 로고    scopus 로고
    • p53 is phosphorylated at the carboxyl terminus and promotes the differentiation of human HaCaT keratinocytes
    • Paramio JM, Segrelles C, Lain S, Gomez-Casero E, Lane DP, et al. (2000) p53 is phosphorylated at the carboxyl terminus and promotes the differentiation of human HaCaT keratinocytes. Mol Carcinog 29: 251-262.
    • (2000) Mol Carcinog , vol.29 , pp. 251-262
    • Paramio, J.M.1    Segrelles, C.2    Lain, S.3    Gomez-Casero, E.4    Lane, D.P.5
  • 31
    • 14644427199 scopus 로고    scopus 로고
    • p73 is a p53-independent, Sp1-dependent repressor of cyclin B1 transcription
    • Innocente SA, Lee JM, (2005) p73 is a p53-independent, Sp1-dependent repressor of cyclin B1 transcription. Biochem Biophys Res Commun 329: 713-718.
    • (2005) Biochem Biophys Res Commun , vol.329 , pp. 713-718
    • Innocente, S.A.1    Lee, J.M.2
  • 33
    • 33751230475 scopus 로고    scopus 로고
    • p63 regulates proliferation and differentiation of developmentally mature keratinocytes
    • Truong AB, Kretz M, Ridky TW, Kimmel R, Khavari PA, (2006) p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev 20: 3185-3197.
    • (2006) Genes Dev , vol.20 , pp. 3185-3197
    • Truong, A.B.1    Kretz, M.2    Ridky, T.W.3    Kimmel, R.4    Khavari, P.A.5
  • 34
    • 0942301281 scopus 로고    scopus 로고
    • p63 is the molecular switch for initiation of an epithelial stratification program
    • Koster MI, Kim S, Mills AA, DeMayo FJ, Roop DR, (2004) p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev 18: 126-131.
    • (2004) Genes Dev , vol.18 , pp. 126-131
    • Koster, M.I.1    Kim, S.2    Mills, A.A.3    DeMayo, F.J.4    Roop, D.R.5
  • 35
    • 0036060364 scopus 로고    scopus 로고
    • Inhibition of serum- and calcium-induced terminal differentiation of human keratinocytes by HPV 16 E6: study of the association with p53 degradation, inhibition of p53 transactivation, and binding to E6BP
    • Sherman L, Itzhaki H, Jackman A, Chen JJ, Koval D, et al. (2002) Inhibition of serum- and calcium-induced terminal differentiation of human keratinocytes by HPV 16 E6: study of the association with p53 degradation, inhibition of p53 transactivation, and binding to E6BP. Virology 292: 309-320.
    • (2002) Virology , vol.292 , pp. 309-320
    • Sherman, L.1    Itzhaki, H.2    Jackman, A.3    Chen, J.J.4    Koval, D.5
  • 36
    • 34248175814 scopus 로고    scopus 로고
    • Regulation of Notch1 gene expression by p53 in epithelial cells
    • Yugawa T, Handa K, Narisawa-Saito M, Ohno S, Fujita M, et al. (2007) Regulation of Notch1 gene expression by p53 in epithelial cells. Mol Cell Biol 27: 3732-3742.
    • (2007) Mol Cell Biol , vol.27 , pp. 3732-3742
    • Yugawa, T.1    Handa, K.2    Narisawa-Saito, M.3    Ohno, S.4    Fujita, M.5
  • 37
    • 0037370310 scopus 로고    scopus 로고
    • Notch1 functions as a tumor suppressor in mouse skin
    • Nicolas M, Wolfer A, Raj K, Kummer JA, Mill P, et al. (2003) Notch1 functions as a tumor suppressor in mouse skin. Nat Genet 33: 416-421.
    • (2003) Nat Genet , vol.33 , pp. 416-421
    • Nicolas, M.1    Wolfer, A.2    Raj, K.3    Kummer, J.A.4    Mill, P.5
  • 38
    • 33645894992 scopus 로고    scopus 로고
    • Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
    • Nguyen BC, Lefort K, Mandinova A, Antonini D, Devgan V, et al. (2006) Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev 20: 1028-1042.
    • (2006) Genes Dev , vol.20 , pp. 1028-1042
    • Nguyen, B.C.1    Lefort, K.2    Mandinova, A.3    Antonini, D.4    Devgan, V.5
  • 39
    • 0028589636 scopus 로고
    • Differential expression of heat shock protein 70 (HSP70) and heat shock cognate protein 70 (HSC70) in human epidermis
    • Boehncke WH, Dahlke A, Zollner TM, Sterry W, (1994) Differential expression of heat shock protein 70 (HSP70) and heat shock cognate protein 70 (HSC70) in human epidermis. Arch Dermatol Res 287: 68-71.
    • (1994) Arch Dermatol Res , vol.287 , pp. 68-71
    • Boehncke, W.H.1    Dahlke, A.2    Zollner, T.M.3    Sterry, W.4
  • 40
    • 13444250890 scopus 로고    scopus 로고
    • DeltaNp63alpha up-regulates the Hsp70 gene in human cancer
    • Wu G, Osada M, Guo Z, Fomenkov A, Begum S, et al. (2005) DeltaNp63alpha up-regulates the Hsp70 gene in human cancer. Cancer Res 65: 758-766.
    • (2005) Cancer Res , vol.65 , pp. 758-766
    • Wu, G.1    Osada, M.2    Guo, Z.3    Fomenkov, A.4    Begum, S.5
  • 41
    • 0027469281 scopus 로고
    • Regulation of the human hsp70 promoter by p53
    • Agoff SN, Hou J, Linzer DI, Wu B, (1993) Regulation of the human hsp70 promoter by p53. Science 259: 84-87.
    • (1993) Science , vol.259 , pp. 84-87
    • Agoff, S.N.1    Hou, J.2    Linzer, D.I.3    Wu, B.4
  • 42
    • 0032929014 scopus 로고    scopus 로고
    • p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding
    • Lee KC, Crowe AJ, Barton MC, (1999) p53-mediated repression of alpha-fetoprotein gene expression by specific DNA binding. Mol Cell Biol 19: 1279-1288.
    • (1999) Mol Cell Biol , vol.19 , pp. 1279-1288
    • Lee, K.C.1    Crowe, A.J.2    Barton, M.C.3
  • 43
    • 65849180296 scopus 로고    scopus 로고
    • DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodeling
    • Banerjee T, Nath S, Roychoudhury S, (2009) DNA damage induced p53 downregulates Cdc20 by direct binding to its promoter causing chromatin remodeling. Nucleic Acids Res 37: 2688-2698.
    • (2009) Nucleic Acids Res , vol.37 , pp. 2688-2698
    • Banerjee, T.1    Nath, S.2    Roychoudhury, S.3
  • 44
    • 0027318117 scopus 로고
    • Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53
    • Mack DH, Vartikar J, Pipas JM, Laimins LA, (1993) Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53. Nature 363: 281-283.
    • (1993) Nature , vol.363 , pp. 281-283
    • Mack, D.H.1    Vartikar, J.2    Pipas, J.M.3    Laimins, L.A.4
  • 45
    • 20244390478 scopus 로고    scopus 로고
    • Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters
    • Imbriano C, Gurtner A, Cocchiarella F, Di Agostino S, Basile V, et al. (2005) Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters. Mol Cell Biol 25: 3737-3751.
    • (2005) Mol Cell Biol , vol.25 , pp. 3737-3751
    • Imbriano, C.1    Gurtner, A.2    Cocchiarella, F.3    Di Agostino, S.4    Basile, V.5
  • 47
    • 0035839535 scopus 로고    scopus 로고
    • Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1
    • Li B, Lee MY, (2001) Transcriptional regulation of the human DNA polymerase delta catalytic subunit gene POLD1 by p53 tumor suppressor and Sp1. J Biol Chem 276: 29729-29739.
    • (2001) J Biol Chem , vol.276 , pp. 29729-29739
    • Li, B.1    Lee, M.Y.2
  • 48
    • 20144383378 scopus 로고    scopus 로고
    • Tumor suppressor p53 represses transcription of RECQ4 helicase
    • Sengupta S, Shimamoto A, Koshiji M, Pedeux R, Rusin M, et al. (2005) Tumor suppressor p53 represses transcription of RECQ4 helicase. Oncogene 24: 1738-1748.
    • (2005) Oncogene , vol.24 , pp. 1738-1748
    • Sengupta, S.1    Shimamoto, A.2    Koshiji, M.3    Pedeux, R.4    Rusin, M.5
  • 49
    • 0033215387 scopus 로고    scopus 로고
    • Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a
    • Murphy M, Ahn J, Walker KK, Hoffman WH, Evans RM, et al. (1999) Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a. Genes Dev 13: 2490-2501.
    • (1999) Genes Dev , vol.13 , pp. 2490-2501
    • Murphy, M.1    Ahn, J.2    Walker, K.K.3    Hoffman, W.H.4    Evans, R.M.5
  • 50
    • 0038751837 scopus 로고    scopus 로고
    • Transcriptional repression mediated by the p53 tumour suppressor
    • Ho J, Benchimol S, (2003) Transcriptional repression mediated by the p53 tumour suppressor. Cell Death Differ 10: 404-408.
    • (2003) Cell Death Differ , vol.10 , pp. 404-408
    • Ho, J.1    Benchimol, S.2
  • 51
    • 33845230349 scopus 로고    scopus 로고
    • Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene
    • Maeda Y, Hwang-Verslues WW, Wei G, Fukazawa T, Durbin ML, et al. (2006) Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene. Biochem J 400: 303-313.
    • (2006) Biochem J , vol.400 , pp. 303-313
    • Maeda, Y.1    Hwang-Verslues, W.W.2    Wei, G.3    Fukazawa, T.4    Durbin, M.L.5
  • 52
    • 0031840253 scopus 로고    scopus 로고
    • ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins
    • Waterman MJ, Stavridi ES, Waterman JL, Halazonetis TD, (1998) ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins. Nat Genet 19: 175-178.
    • (1998) Nat Genet , vol.19 , pp. 175-178
    • Waterman, M.J.1    Stavridi, E.S.2    Waterman, J.L.3    Halazonetis, T.D.4
  • 54
    • 77950361185 scopus 로고    scopus 로고
    • Mechanistic differences in the transcriptional activation of p53 by 14-3-3 isoforms
    • Rajagopalan S, Sade RS, Townsley FM, Fersht AR, (2010) Mechanistic differences in the transcriptional activation of p53 by 14-3-3 isoforms. Nucleic Acids Res 38: 893-906.
    • (2010) Nucleic Acids Res , vol.38 , pp. 893-906
    • Rajagopalan, S.1    Sade, R.S.2    Townsley, F.M.3    Fersht, A.R.4
  • 55
    • 0026598362 scopus 로고
    • Delayed onset of epidermal differentiation in psoriasis
    • Bernerd F, Magnaldo T, Darmon M, (1992) Delayed onset of epidermal differentiation in psoriasis. J Invest Dermatol 98: 902-910.
    • (1992) J Invest Dermatol , vol.98 , pp. 902-910
    • Bernerd, F.1    Magnaldo, T.2    Darmon, M.3
  • 57
    • 0037007427 scopus 로고    scopus 로고
    • Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes
    • Qin JZ, Chaturvedi V, Denning MF, Bacon P, Panella J, et al. (2002) Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes. Oncogene 21: 2991-3002.
    • (2002) Oncogene , vol.21 , pp. 2991-3002
    • Qin, J.Z.1    Chaturvedi, V.2    Denning, M.F.3    Bacon, P.4    Panella, J.5
  • 58
    • 0345304246 scopus 로고    scopus 로고
    • Positive and negative regulation of deltaN-p63 promoter activity by p53 and deltaN-p63-alpha contributes to differential regulation of p53 target genes
    • Harmes DC, Bresnick E, Lubin EA, Watson JK, Heim KE, et al. (2003) Positive and negative regulation of deltaN-p63 promoter activity by p53 and deltaN-p63-alpha contributes to differential regulation of p53 target genes. Oncogene 22: 7607-7616.
    • (2003) Oncogene , vol.22 , pp. 7607-7616
    • Harmes, D.C.1    Bresnick, E.2    Lubin, E.A.3    Watson, J.K.4    Heim, K.E.5
  • 59
    • 3142729912 scopus 로고    scopus 로고
    • Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation
    • Murphy PJ, Galigniana MD, Morishima Y, Harrell JM, Kwok RP, et al. (2004) Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation. J Biol Chem 279: 30195-30201.
    • (2004) J Biol Chem , vol.279 , pp. 30195-30201
    • Murphy, P.J.1    Galigniana, M.D.2    Morishima, Y.3    Harrell, J.M.4    Kwok, R.P.5
  • 60
    • 33744943247 scopus 로고    scopus 로고
    • Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells
    • Chua CC, Liu X, Gao J, Hamdy RC, Chua BH, (2006) Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells. Am J Physiol Heart Circ Physiol 290: H2606-2613.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Chua, C.C.1    Liu, X.2    Gao, J.3    Hamdy, R.C.4    Chua, B.H.5
  • 61
    • 77956824672 scopus 로고    scopus 로고
    • p73 participates in male germ cells apoptosis induced by etoposide
    • Codelia VA, Cisterna M, Alvarez AR, Moreno RD, (2010) p73 participates in male germ cells apoptosis induced by etoposide. Mol Hum Reprod 16: 734-742.
    • (2010) Mol Hum Reprod , vol.16 , pp. 734-742
    • Codelia, V.A.1    Cisterna, M.2    Alvarez, A.R.3    Moreno, R.D.4
  • 62
    • 79955542144 scopus 로고    scopus 로고
    • Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (TAP63alpha)
    • Sun R, Zhang Y, Lv Q, Liu B, Jin M, et al. (2011) Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (TAP63alpha). J Biol Chem 286: 15918-15928.
    • (2011) J Biol Chem , vol.286 , pp. 15918-15928
    • Sun, R.1    Zhang, Y.2    Lv, Q.3    Liu, B.4    Jin, M.5
  • 63
    • 0042856287 scopus 로고    scopus 로고
    • Role of protein kinase C and the Sp1-p53 complex in activation of p21(WAF-1) expression by 12-O-tetradecanoylphorbol-13-acetate in human T cells
    • Schavinsky-Khrapunsky Y, Huleihel M, Aboud M, Torgeman A, (2003) Role of protein kinase C and the Sp1-p53 complex in activation of p21(WAF-1) expression by 12-O-tetradecanoylphorbol-13-acetate in human T cells. Oncogene 22: 5315-5324.
    • (2003) Oncogene , vol.22 , pp. 5315-5324
    • Schavinsky-Khrapunsky, Y.1    Huleihel, M.2    Aboud, M.3    Torgeman, A.4
  • 64
    • 16344381702 scopus 로고    scopus 로고
    • p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation
    • Ou YH, Chung PH, Sun TP, Shieh SY, (2005) p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation. Mol Biol Cell 16: 1684-1695.
    • (2005) Mol Biol Cell , vol.16 , pp. 1684-1695
    • Ou, Y.H.1    Chung, P.H.2    Sun, T.P.3    Shieh, S.Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.