Physical and functional interactions between members of the tumour suppressor p53 and the Sp families of transcription factors: Importance for the regulation of genes involved in cell-cycle arrest and apoptosis

Biochemical Journal

Volumn 389, Issue 2, 2005, Pages 443-455

  Koutsodontis, George ^a   Vasilaki, Eleftheria ^a   Chou, Wan Chih ^a,c   Papakosta, Paraskevi ^a   Kardassis, Dimitris ^a,b  

^a UNIVERSITY OF CRETE   (Greece)

^b INSTITUTE OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY   (Greece)

^c Novartis Pharma GmbH   (Austria)

Author keywords

Apoptosis; Cell cycle; p21; p53; p53 up regulated mediator of apoptosis (PUMA); Specificity protein 1 (Sp1)

Indexed keywords

AMINO ACIDS; BINDING ENERGY; BIOASSAY; CELL CULTURE; CHEMOTHERAPY; DRUG INTERACTIONS; GENES; TUMORS;

CELLULAR RESPONSES; MUTANTS; PROMOTERS; TUMOR SUPPRESSORS;

PROTEINS;

CYCLIN DEPENDENT KINASE INHIBITOR 1; GLUTATHIONE TRANSFERASE; PROTEIN P53; PROTEIN P53 UPREGULATED MEDIATOR OF APOPTOSIS; PROTEIN P63; PROTEIN P73; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP2; TRANSCRIPTION FACTOR SP3; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CONTROLLED STUDY; DNA BINDING; DROSOPHILA; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL CYCLE; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; HUMANS; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; SP TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 22544441310     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041980     Document Type: Article

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