A synthetic compound, 1,5-bis(2-methoxyphenyl)penta- 1,4-dien-3-one (B63), induces apoptosis and activates endoplasmic reticulum stress in non-small cell lung cancer cells

International Journal of Cancer

Volumn 131, Issue 6, 2012, Pages 1455-1465

  Xiao, Jian ^a   Wang, Yi ^a   Peng, Jing ^a   Guo, Lu ^a   Hu, Jie ^a   Cao, Menghua ^a   Zhang, Xie ^a   Zhang, Hanqing ^a   Wang, Zhouguang ^a   Li, Xiaokun ^a   Yang, Shulin ^b   Yang, Huiling ^c   Liang, Guang ^a,b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

1,5 bis(2 methoxyphenyl)penta 1,4 dien 3 one; apoptosis; curcumin; ER stress; non small cell lung cancer

Indexed keywords

1,5 BIS(2 METHOXYPHENYL)PENTA 1,4 DIEN 3 ONE; ACTIVATING TRANSCRIPTION FACTOR 4; CALCIUM; CASPASE 3; CASPASE 9; CCAAT ENHANCER BINDING PROTEIN; CURCUMIN; GLUCOSE REGULATED PROTEIN 78; POLYPHENOL DERIVATIVE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CANCER CELL; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; ENDOPLASMIC RETICULUM STRESS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG FIBROBLAST; LUNG NON SMALL CELL CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR VOLUME;

ANIMALS; ANISOLES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CURCUMIN; ENDOPLASMIC RETICULUM STRESS; HUMANS; KETONES; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C;

EID: 84864153632     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.27406     Document Type: Article

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