Desipramine induces apoptosis in rat glioma cells via endoplasmic reticulum stress-dependent CHOP pathway

Journal of Neuro-Oncology

Volumn 101, Issue 1, 2011, Pages 41-48

  Ma, Jian ^a   Qiu, Yu ^a   Yang, Lan ^a   Peng, Liang ^a   Xia, Zheng ^a   Hou, Li Na ^a   Fang, Chao ^a   Qi, Hong ^a   Chen, Hong Zhuan ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Apoptosis; CHOP GADD153; Desipramine; Endoplasmic reticulum stress; GADD34

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; DESIPRAMINE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; MESSENGER RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL VIABILITY; CHROMATIN CONDENSATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME ACTIVITY; GLIOMA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; APOPTOSIS; BLOTTING, WESTERN; CELL LINE, TUMOR; DESIPRAMINE; ENDOPLASMIC RETICULUM; GLIOMA; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR CHOP;

EID: 78651298891     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-010-0237-2     Document Type: Article

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