Mutations of the serine protease CAP1/Prss8 lead to reduced embryonic viability, skin defects, and decreased ENaC activity

American Journal of Pathology

Volumn 181, Issue 2, 2012, Pages 605-615

  Frateschi, Simona ^a   Keppner, Anna ^a   Malsure, Sumedha ^a   Iwaszkiewicz, Justyna ^a   Sergi, Chloé ^a   Merillat, Anne Marie ^a   Fowler Jaeger, Nicole ^a   Randrianarison, Nadia ^b   Planès, Carole ^b   Hummler, Edith ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITÉ PARIS 13   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CAP1 PROTEIN; EPITHELIAL SODIUM CHANNEL; PRSS8 PROTEIN; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; COLON MUCOSA; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; ENZYME ACTIVITY; ENZYME INACTIVATION; FEMALE; GENE MUTATION; GLYCOSYLATION; HAIRLESS RAT; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VIVO STUDY; INTESTINE; MALE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN STRUCTURE; RAT; SKIN DEFECT; WEIGHT REDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BODY WEIGHT; DEHYDRATION; EMBRYO, MAMMALIAN; EPITHELIAL SODIUM CHANNELS; GENE EXPRESSION REGULATION; HAIR; HEK293 CELLS; HUMANS; INHERITANCE PATTERNS; ION CHANNEL GATING; MICE; MODELS, ANIMAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; ORGAN SPECIFICITY; PHENOTYPE; PROTEIN STRUCTURE, TERTIARY; RATS; SERINE ENDOPEPTIDASES; SKIN; STRUCTURAL HOMOLOGY, PROTEIN; XENOPUS;

EID: 84864148752     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.05.007     Document Type: Article

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