Oligomerization and maturation of Na,K-ATPase: Functional interaction of the cytoplasmic NH2 terminus of the β subunit with the α subunit

Journal of Cell Biology

Volumn 133, Issue 6, 1996, Pages 1193-1204

  Geering, Käthi ^a   Beggah, Ahmed ^a   Good, Peter ^b   Girardet, Sylvie ^a   Roy, Sophie ^a   Schaer, Danièle ^a   Jaunin, Philippe ^a  

^a University of Lausanne Departement de Pharmacologie et de Toxicologie   (Switzerland)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

STROPHANTHUS GRATUS; ANIMALIA;

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM);

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME DEGRADATION; ENZYME SUBUNIT; NONHUMAN; OLIGOMERIZATION; OOCYTE; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PROTEIN INTERACTION; SODIUM TRANSPORT; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BIOLOGICAL TRANSPORT; BREFELDIN A; CYCLOPENTANES; ENDOPLASMIC RETICULUM; MOLECULAR SEQUENCE DATA; NA(+)-K(+)-EXCHANGING ATPASE; OOCYTES; PROTEIN CONFORMATION; PROTEIN SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS C-MYC; RECOMBINANT FUSION PROTEINS; RNA, COMPLEMENTARY; RUBIDIUM RADIOISOTOPES; TRYPSIN; XENOPUS;

EID: 0029905492     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.133.6.1193     Document Type: Article

References (38)

1. Ackermann, U., and K. Geering. 1990. Mutual dependence of Na, K-ATP-ase α-subunits and β-subunits for correct posttranslational processing and intracellular transport. FEBS Lett. 269:105-108.
2. Beggah, A.T., P. Beguin, P. Jaunin, M.C. Peitsch, and K. Geering. 1993. Hydrophobie C-terminal amino acids in the β-subunit are involved in assembly with the α-subunit of Na, K-ATPase. Biochemistry. 32:14117-14124.
3. Blanco, G., A.W. Detomaso, J. Koster, Z.J. Xie, and R.W. Mercer. 1994. The α-subunit of the Na,K-ATPase has catalytic activity independent of the β-subunit. J. Biol. Chem. 269:23420-23425.
4. +-ATPase using an inhibitory monoclonal antibody. Am. J. Physiol. 265:C1562-C1570.
5. Doms, R.W., R.A. Lamb, J.K. Rose, and A. Helenius. 1993. Folding and assembly of viral membrane proteins. Virology. 193:545-562.
6. +. J. Biol. Chem. 269:6550-6557.
7. Fambrough, D.M., M.V. Lemas, M. Hamrick, M. Emerick, K.J. Renaud, E.M. Inman, B. Hwang, and K. Takeyasu. 1994. Analysis of subunit assembly of the Na-K-ATPase. Am. J. Physiol. 266:C579-C589.
8. Geering, K. 1990. Subunit assembly and functional maturation of Na,K-ATPase. J. Membr. Biol. 115:109-121.
9. Geering, K. 1991. The functional role of the β-subunit in the maturation and intracellular transport of Na,K-ATPase. FEBS Lett. 285:189-193.
10. +-ATPase in Xenopus oocytes. Am. J. Physiol. 257:C851-C858.
11. +)-ATPase subunits. Biochem. J. 20:6684-6691.
12. Good, P.J., R.C. Welch, A. Barkan, M.B. Somasekhar, and J.E. Mertz. 1988. Both VP2 and VP3 are synthesized from each of the alternatively spliced late 19S RNA species of simian virus 40. J. Virol. 62:944-953.
13. +-ATPase expressed during early development of Xenopus laevis. Proc. Natl. Acad. Sci. USA. 87:9088-9092.
14. Green, W.N., and T. Claudio. 1993. Acetylcholine receptor assembly: subunit folding and oligomerization occur sequentially. Cell. 74:57-69.
15. Helenius, A., T. Marquardt, and I. Braakman. 1992. The endoplasmic reticulum as a protein-folding compartment. Trends Cell Biol. 2:227-231.
16. +-ATPase α subunit. Mol. Cell. Biol. 9:5742-5745.
17. Jaisser, F., CM. Canessa, J.D. Horisberger, and B.C. Rossier. 1992. Primary sequence and functional expression of a novel ouabain-resistant Na,K-ATPase: The β-subunit modulates potassium activation of the Na,K-pump. J. Biol. Chem. 267:16895-16903.
18. Jaisser, F., P. Jaunin, K. Geering, B.C. Rossier, and J.D. Horisberger. 1994. Modulation of the Na,K-pump function by β-subunit isoforms. J. Gen. Physiol. 103:605-623.
19. Jaunin, P., J.D. Horisberger, K. Richter, P.J. Good, B.C. Rossier, and K. Geering. 1992. Processing, intracellular transport, and functional expression of endogenous and exogenous α-β3 Na,K-ATPase complexes in Xenopus oocytes. J. Biol. Chem. 267:577-585.
20. Jaunin, P., F. Jaisser, A.T. Beggah, K. Takeyasu, P. Mangeat, B.C. Rossier, J.D. Horisberger, and K. Geering. 1993. Role of the transmembrane and extracytoplasmic domain of β-subunits in subunit assembly, intracellular transport, and functional expression of Na,K-pumps. J. Cell Biol. 123:1751-1759.
21. 2 conformational transition in Na,K-pump and Ca-pump protein. J. Membr. Biol. 103:95-120.
22. +-ATPase. Methods Enzymol. 156:291-301.
23. 831 of the α chain of Na/K-ATPase at the cytoplasmic surface. Implication for topological models. J. Biol. Chem. 268:3471-3478.
24. Kawakami, K., and K. Nagano. 1988. The transmembrane segment of the human Na,K-ATPase β-subunit acts as the membrane incorporation signal. J. Biochem. 103:54-60.
25. Kolodziej, P.A., and R.A. Young. 1991. Epitope tagging and protein surveillance. Methods Enzymol. 194:508-519.
26. Lippincott-Schwartz, J., J.G. Donaldson, A. Schweizer, E.G. Berger, H.-P. Hauri, L.C. Yuan, and R.D. Klausner. 1990. Microtubule-dependent retrograde transport of proteins into the ER in presence of brefeldin A suggests an ER recycling pathway. Cell. 60:821-836.
27. Lutsenko, S., and J.H. Kaplan. 1994. Molecular events in close proximity to the membrane associated with the binding of ligands to the Na,K-ATPase. J. Biol. Chem. 269:4555-4564.
28. Melton, D.A., P.A. Krieg, M.R. Rebagliati, T. Maniatis, K. Zinn, and M.R. Green. 1984. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res. 12:7035-7056.
29. Nelson, R.M., and G.L. Long. 1989. A general method of site-specific mutagenesis using a modification of the Thermus aquaticus polymerase chain reaction. Anal. Biochem. 180:147-151.
30. +-ATPase isozyme during meiotic maturation of Xenopus laevis oocytes. Am. J. Physiol. 262:C1520-C1530.
31. Renaud, K.J., E.M. Inman, and D.M. Fambrough. 1991. Cytoplasmic and transmembrane domain deletions of Na,K-ATPase β-subunit: effects on subunit assembly and intracellular transport. J. Biol. Chem. 266:20491-20497.
32. Sanger, F., S. Nicklen, and A.R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA. 74:5463-5467.
33. +-activated ATPase from ox brain. Eur. J. Biochem. 1:334-343.
34. Schmalzing, G., S. Kroner, M. Schachner, and S. Gloor. 1992. The adhesion molecule on glia (AMOG/β2) and α1 subunits assemble to functional sodium pumps in Xenopus-oocytes. J. Biol. Chem. 267:20212-20216.
35. Shainskaya, A., and S.J.D. Karlish. 1994. Evidence that the cation occlusion domain of Na/K-ATPase consists of a complex of membrane-spanning segments: analysis of limit membrane-embedded tryptic fragments. J. Biol. Chem. 269:10780-10789.
36. Shainskaya, A., and S.J.D. Karlish. 1996. Modulation of cation occlusion on Na/K-ATPase by the cytoplasmic domain of the β subunit. J. Biol. Chem. 271:10309-10316.
37. +-ATPase and its localization in A6 kidney cells. Am. J. Physiol. 256:F1034-F1043.
38. +-ATPase transport. Am. J. Physiol. 256:C958-C966.