Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells

PLoS ONE

Volumn 3, Issue 4, 2008, Pages

  Kondo, Yutaka ^a,b   Shen, Lanlan ^b   Ahmed, Saira ^b   Boumber, Yanis ^b   Sekido, Yoshitaka ^a   Haddad, Bassem R ^c   Issa, Jean Pierre J ^b  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b UNIVERSITY OF TEXAS   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE METHYLTRANSFERASE; PROTEIN P16; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; METHYLTRANSFERASE; RASSF1 PROTEIN, HUMAN; REPRESSOR PROTEIN; SUV39H1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DISRUPTION; CELL STRUCTURE; CENTROSOME; CHROMOSOMAL INSTABILITY; CHROMOSOME DUPLICATION; CHROMOSOME NUMBER; CHROMOSOME STRUCTURE; CONTROLLED STUDY; DNA CONTENT; DOWN REGULATION; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION REGULATION; GENETIC GAIN; HUMAN; HUMAN CELL; KARYOTYPE; KNOCKOUT GENE; LUNG CANCER; MICROARRAY ANALYSIS; PHENOTYPE; PROSTATE CANCER; PROTEIN FUNCTION; PROTEIN TARGETING; UPREGULATION; ENZYMOLOGY; GENETIC EPIGENESIS; GENETICS; METABOLISM; NEOPLASM; PATHOLOGY; TELOMERE; TUMOR CELL LINE;

CELL LINE, TUMOR; CENTROSOME; CHROMOSOMAL INSTABILITY; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DOWN-REGULATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; LYSINE; METHYLTRANSFERASES; NEOPLASMS; REPRESSOR PROTEINS; TELOMERE; TUMOR SUPPRESSOR PROTEINS;

EID: 44249128891     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002037     Document Type: Article

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