Effects of the natural flavone trimethylapigenin on cardiac potassium currents

Biochemical Pharmacology

Volumn 84, Issue 4, 2012, Pages 498-506

  Liu, Yi ^a,b   Xu, Xiao Hui ^a   Liu, Zheng ^c   Du, Xin Ling ^c   Chen, Kui Hao ^a,b   Xin, Xin ^a,b   Jin, Zhen Dong ^a   Shen, Ji Zhong ^a,b   Hu, Yan ^a,b   Li, Gui Rong ^d   Jin, Man Wen ^a,b  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b Key Laboratory for Drug Target Researches and Pharmacodynamic Evaluation of Hubei Province   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Acetylcholine activated K + current; hKv1.5; Open channel blocker; Trimethylapigenin

Indexed keywords

3,5,7,3',4' PENTAMETHYLQUECERTIN; 3,7,3',4' TETRAMETHYLQUECERTIN; 5,7,4' TRIMETHYLAPIGENIN; 7,4' DIMETHYLAPIGENIN; ACETYLCHOLINE; APIGENIN; DELAYED RECTIFIER POTASSIUM CHANNEL; FLAVONE; POTASSIUM CHANNEL HERG; POTASSIUM CHANNEL KV1.5; QUERCETIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ATRIAL MYOCYTE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HEART ATRIUM; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MALE; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; TRANSIENT OUTWARD POTASSIUM CURRENT;

ANIMALS; APIGENIN; ETHER-A-GO-GO POTASSIUM CHANNELS; FEMALE; HEART ATRIA; HEK293 CELLS; HUMANS; KV1.5 POTASSIUM CHANNEL; MALE; MYOCARDIUM; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84864138148     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.05.002     Document Type: Article

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