Molecular basis for a high-potency open-channel block of Kv1.5 channel by the endocannabinoid anandamide

Molecular Pharmacology

Volumn 77, Issue 5, 2010, Pages 751-758

  Moreno Galindo, Eloy G ^a   Barrio Echavarría, Gabriel F ^a   Vásquez, José C ^a   Decher, Niels ^b   Sachse, Frank B ^c,d   Tristani Firouzi, Martin ^c   Sánchez Chapula, José A ^a   Navarro Polanco, Ricardo A ^a  

^a UNIVERSIDAD DE COLIMA   (Mexico)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^d University of Utah   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANANDAMIDE; ENDOCANNABINOID; POTASSIUM CHANNEL KV1.5;

AMINO ACID SEQUENCE; ARTICLE; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; HUMAN; HUMAN CELL; IC 50; MOLECULAR DOCKING; MOLECULAR MODEL; MUTAGENESIS; PATCH CLAMP; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ARACHIDONIC ACIDS; BINDING SITES; CANNABINOIDS; CELL LINE; CELL MEMBRANE; CLONING, MOLECULAR; CYTOPLASM; HUMANS; KIDNEY; KV1.5 POTASSIUM CHANNEL; MUTAGENESIS, SITE-DIRECTED; PLASMIDS; POLYMERASE CHAIN REACTION; POLYUNSATURATED ALKAMIDES;

EID: 77951086898     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.063008     Document Type: Article

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