메뉴 건너뛰기




Volumn 57, Issue 2, 2010, Pages 103-111

Trans-10,cis-12-CLA-caused lipodystrophy is associated with profound changes of fatty acid profiles of liver, white adipose tissue and erythrocytes in mice: Possible link to tissue-specific alterations of fatty acid desaturation

Author keywords

Desaturation index; Liver steatosis; Stearoyl CoA desaturase; t10,c12 conjugated linoleic acid; White adipose

Indexed keywords

ACYL COENZYME A DESATURASE; CONJUGATED LINOLEIC ACID; FATTY ACID ESTER; MONOUNSATURATED FATTY ACID; SUNFLOWER OIL;

EID: 77957302602     PISSN: 02506807     EISSN: None     Source Type: Journal    
DOI: 10.1159/000319877     Document Type: Article
Times cited : (30)

References (59)
  • 1
    • 31044454934 scopus 로고    scopus 로고
    • Overweight and obesity in Germany 1984-2003. Bundesgesundheitsblatt Gesundheitsforschung
    • Mensink GB, Lampert T, Bergmann E: Overweight and obesity in Germany 1984-2003. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2005;48:1348-1356.
    • (2005) Gesundheitsschutz , vol.48 , pp. 1348-1356
    • Mensink, G.B.1    Lampert, T.2    Bergmann, E.3
  • 3
    • 33847324492 scopus 로고    scopus 로고
    • The role of conjugated linoleic acid in reducing body fat and preventing holiday weight gain
    • Watras AC, Buchholz AC, Close RN, Zhang Z, Schoeller DA: The role of conjugated linoleic acid in reducing body fat and preventing holiday weight gain. Int J Obes (Lond) 2007;31:481-487.
    • (2007) Int. J. Obes (Lond) , vol.31 , pp. 481-487
    • Watras, A.C.1    Buchholz, A.C.2    Close, R.N.3    Zhang, Z.4    Schoeller, D.A.5
  • 5
    • 0036730666 scopus 로고    scopus 로고
    • Treatment with trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome
    • Riserus U, Arner P, Brismar K, Vessby B: Treatment with trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome. Diabetes Care 2002;25:1516-1521.
    • (2002) Diabetes Care , vol.25 , pp. 1516-1521
    • Riserus, U.1    Arner, P.2    Brismar, K.3    Vessby, B.4
  • 6
    • 0037044425 scopus 로고    scopus 로고
    • Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: A potential link to fatty acid-induced insulin resistance
    • Riserus U, Basu S, Jovinge S, Fredrikson GN, Arnlov J, Vessby B: Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance. Circulation 2002;106:1925-1929.
    • (2002) Circulation , vol.106 , pp. 1925-1929
    • Riserus, U.1    Basu, S.2    Jovinge, S.3    Fredrikson, G.N.4    Arnlov, J.5    Vessby, B.6
  • 7
    • 49449090273 scopus 로고    scopus 로고
    • An oil mixture with trans-10, ris-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in post1 menopausal women
    • Tholstrup T, Raff M, Straarup EM, Lund P, Basu S, Bruun JM: An oil mixture with trans-10, ris-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in post1 menopausal women. J Nutr 2008;138:1445-1451.
    • (2008) J. Nutr. , vol.138 , pp. 1445-1451
    • Tholstrup, T.1    Raff, M.2    Straarup, E.M.3    Lund, P.4    Basu, S.5    Bruun, J.M.6
  • 8
    • 33748291462 scopus 로고    scopus 로고
    • Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue
    • Poirier H, Shapiro JS, Kim RJ, Lazar MA: Nutritional supplementation with trans-10, cis-12-conjugated linoleic acid induces inflammation of white adipose tissue. Diabetes 2006;55:1634-1641.
    • (2006) Diabetes , vol.55 , pp. 1634-1641
    • Poirier, H.1    Shapiro, J.S.2    Kim, R.J.3    Lazar, M.A.4
  • 11
    • 1542404084 scopus 로고    scopus 로고
    • Theroleofstearoyl-CoA desaturase in body weight regulation
    • Dobrzyn A, Ntambi JM: Theroleofstearoyl-CoA desaturase in body weight regulation. Trends Cardiovasc Med 2004;14:77-81.
    • (2004) Trends Cardiovasc. Med. , vol.14 , pp. 77-81
    • Dobrzyn, A.1    Ntambi, J.M.2
  • 12
    • 0032581382 scopus 로고    scopus 로고
    • Conjugated linoleic acid decreases hepatic stearoyl-CoA desaturase mRNA expression
    • Lee KN, Pariza MW, Ntambi JM: Conjugated linoleic acid decreases hepatic stearoyl-CoA desaturase mRNA expression. Biochem Biophys Res Commun 1998;248:817-821.
    • (1998) Biochem. Biophys. Res. Commun. , vol.248 , pp. 817-821
    • Lee, K.N.1    Pariza, M.W.2    Ntambi, J.M.3
  • 13
    • 0033929212 scopus 로고    scopus 로고
    • The trans-10, cis-12 isomer of conjugated linoleic acid downregulates stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes
    • Choi Y, Kim YC, Han YB, Park Y, Pariza MW, Ntambi JM: The trans-10, cis-12 isomer of conjugated linoleic acid downregulates stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes. J Nutr 2000;130:1920-1924.
    • (2000) J. Nutr. , vol.130 , pp. 1920-1924
    • Choi, Y.1    Kim, Y.C.2    Han, Y.B.3    Park, Y.4    Pariza, M.W.5    Ntambi, J.M.6
  • 14
    • 0034686661 scopus 로고    scopus 로고
    • Inhibition of hepatic stearoyl-CoA desaturase activity by trans-10, ds-12 conjugated linoleic acid and its derivatives
    • Park Y, Storkson JM, Ntambi JM, Cook ME, Sih CJ, Pariza MW: Inhibition of hepatic stearoyl-CoA desaturase activity by trans-10, ds-12 conjugated linoleic acid and its derivatives. Biochim Biophys Acta 2000;1486:285-292.
    • (2000) Biochim Biophys. Acta. , vol.1486 , pp. 285-292
    • Park, Y.1    Storkson, J.M.2    Ntambi, J.M.3    Cook, M.E.4    Sih, C.J.5    Pariza, M.W.6
  • 15
    • 0034805403 scopus 로고    scopus 로고
    • Regulation of stearoyl-CoA desaturase activity by the trans-10, cis-12 isomer of conjugated linoleic acid in HepG2 cells
    • Choi Y, Park Y, Pariza MW, Ntambi JM: Regulation of stearoyl-CoA desaturase activity by the trans-10, cis-12 isomer of conjugated linoleic acid in HepG2 cells. Biochem Biophys Res Commun 2001;284:689-693.
    • (2001) Biochem. Biophys. Res. Commun. , vol.284 , pp. 689-693
    • Choi, Y.1    Park, Y.2    Pariza, M.W.3    Ntambi, J.M.4
  • 16
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ: A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959;37:911-917.
    • (1959) Can J. Biochem. Physiol. , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 17
    • 0042624711 scopus 로고    scopus 로고
    • Differences in CLA isomer distribution in cow's milk lipids
    • Kraft J, Collomb M, Möckel P, Sieber R, Jahreis G: Differences in CLA isomer distribution in cow's milk lipids. Lipids 2003;38:657-664.
    • (2003) Lipids , vol.38 , pp. 657-664
    • Kraft, J.1    Collomb, M.2    Möckel, P.3    Sieber, R.4    Jahreis, G.5
  • 18
    • 0032955643 scopus 로고    scopus 로고
    • Evidence that the trans-10,cis-12 isomer of conjugated linoleic acid induces body composition changes in mice
    • Park Y, Storkson JM, Albright KJ, Liu W, Pariza MW: Evidence that the trans-10, cis-12 isomer of conjugated linoleic acid induces body composition changes in mice. Lipids 1999;34:235-241. (Pubitemid 29169626)
    • (1999) Lipids , vol.34 , Issue.3 , pp. 235-241
    • Park, Y.1    Storkson, J.M.2    Albright, K.J.3    Liu, W.4    Pariza, M.W.5
  • 19
    • 1842682842 scopus 로고    scopus 로고
    • Contrasting effects of fl0, cl2-and c9, fll-conjugated linoleic acid isomers on the fatty acid profiles of mouse liver lipids
    • Kelley DS, Bartolini GL, Warren JM, Simon VA, Mackey BE, Erickson KL: Contrasting effects of fl0, cl2-and c9, fll-conjugated linoleic acid isomers on the fatty acid profiles of mouse liver lipids. Lipids 2004;39:135-141.
    • (2004) Lipids , vol.39 , pp. 135-141
    • Kelley, D.S.1    Bartolini, G.L.2    Warren, J.M.3    Simon, V.A.4    Mackey, B.E.5    Erickson, K.L.6
  • 20
    • 33745614287 scopus 로고    scopus 로고
    • Trans-10, cis-12 conjugated linoleic acid inhibits lipoprotein lipase but increases the activity of lipogenic enzymes in adipose tissue from hamsters fed an atherogenic diet
    • Zabala A, Churruca I, Fernández-Quintela A, Rodriguez VM, Macarulla MT, Martinez JA, Portillo MP: Trans-10, cis-12 conjugated linoleic acid inhibits lipoprotein lipase but increases the activity of lipogenic enzymes in adipose tissue from hamsters fed an atherogenic diet. Br J Nutr 2006;95:1112-1119.
    • (2006) Br. J. Nutr. , vol.95 , pp. 1112-1119
    • Zabala, A.1    Churruca, I.2    Fernández-Quintela, A.3    Rodriguez, V.M.4    Macarulla, M.T.5    Martinez, J.A.6    Portillo, M.P.7
  • 22
    • 33644680390 scopus 로고    scopus 로고
    • Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production
    • Chung S, Brown JM, Provo JN, Hopkins R, Mcintosh MK: Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production. J Biol Chem 2005;280:38445-38456.
    • (2005) J. Biol. Chem. , vol.280 , pp. 38445-38456
    • Chung, S.1    Brown, J.M.2    Provo, J.N.3    Hopkins, R.4    Mcintosh, M.K.5
  • 23
    • 12744262842 scopus 로고    scopus 로고
    • Interaction of fish oil and conjugated linoleic acid in affecting hepatic activity of lipogenic enzymes and gene expression in liver and adipose tissue
    • Ide T: Interaction of fish oil and conjugated linoleic acid in affecting hepatic activity of lipogenic enzymes and gene expression in liver and adipose tissue. Diabetes 2005;54:412-423.
    • (2005) Diabetes , vol.54 , pp. 412-423
    • Ide, T.1
  • 24
    • 17044375113 scopus 로고    scopus 로고
    • Conjugated linoleic acid deteriorates insulin resistance in obese/diabetic mice in association with decreased production of adiponectin and leptin
    • Ohashi A, Matsushita Y, Kimura K, Belury MA: Conjugated linoleic acid deteriorates insulin resistance in obese/diabetic mice in association with decreased production of adiponectin and leptin. J Nutr Sci Vitaminol (Tokyo) 2004;50:416-421.
    • (2004) J. Nutr Sci. Vitaminol (Tokyo) , vol.50 , pp. 416-421
    • Ohashi, A.1    Matsushita, Y.2    Kimura, K.3    Belury, M.A.4
  • 25
    • 34250363500 scopus 로고    scopus 로고
    • Effects of trans-10, ds-12 conjugated linoleic acid on the expression of uncoupling proteins in hamsters fed an atherogenic diet
    • Ribot J, Portillo MP, Picó C, Macarulla MT, Palou A: Effects of trans-10, ds-12 conjugated linoleic acid on the expression of uncoupling proteins in hamsters fed an atherogenic diet. Br J Nutr 2007;97:1074-1082.
    • (2007) Br. J. Nutr. , vol.97 , pp. 1074-1082
    • Ribot, J.1    Portillo, M.P.2    Picó, C.3    Macarulla, M.T.4    Palou, A.5
  • 26
    • 0037494961 scopus 로고    scopus 로고
    • Association of liver steatosis with lipid oversecretion and hypotriglyceridemia in C57BL/6j mice fed trans-10, ds-12-linoleic acid
    • Degrace P, Demizieux L, Gresti J, Chardigny JM, Sébédio JL, Clouet P: Association of liver steatosis with lipid oversecretion and hypotriglyceridemia in C57BL/6j mice fed trans-10, ds-12-linoleic acid. FEBS Letters 2003;546:335-339.
    • (2003) FEBS Letters , vol.546 , pp. 335-339
    • Degrace, P.1    Demizieux, L.2    Gresti, J.3    Chardigny, J.M.4    Sébédio, J.L.5    Clouet, P.6
  • 27
    • 33847092559 scopus 로고    scopus 로고
    • Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver
    • Rasooly R, Kelley DS, Greg J, Mackey BE: Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. Br J Nutr 2007;97:58-66.
    • (2007) Br. J. Nutr. , vol.97 , pp. 58-66
    • Rasooly, R.1    Kelley, D.S.2    Greg, J.3    Mackey, B.E.4
  • 28
    • 0035661902 scopus 로고    scopus 로고
    • Trans-10, cis-12 conjugated linoleic acid reduces triglyceride content while differentially affecting peroxisome proliferator activated receptor gamma2 and aP2 expression in 3T3-L1 preadipocytes
    • Evans M, Park Y, Pariza M, Curtis L, Kuebler B, Mcintosh M: Trans-10, cis-12 conjugated linoleic acid reduces triglyceride content while differentially affecting peroxisome proliferator activated receptor gamma2 and aP2 expression in 3T3-L1 preadipocytes. Lipids 2001;36:1223-1232.
    • (2001) Lipids , vol.36 , pp. 1223-1232
    • Evans, M.1    Park, Y.2    Pariza, M.3    Curtis, L.4    Kuebler, B.5    Mcintosh, M.6
  • 30
    • 0037432675 scopus 로고    scopus 로고
    • Trans-10, cis-12 CLA inhibits differentiation of 3T3-L1 adipocytes and decreases PPAR7 expression
    • Kang K, Liu W, Albright KJ, Park Y, Pariza MW: Trans-10, cis-12 CLA inhibits differentiation of 3T3-L1 adipocytes and decreases PPAR7 expression. Biochem Biophys Res Commun 2003;303:795-799.
    • (2003) Biochem. Biophys. Res. Commun. , vol.303 , pp. 795-799
    • Kang, K.1    Liu, W.2    Albright, K.J.3    Park, Y.4    Pariza, M.W.5
  • 31
    • 0037629888 scopus 로고    scopus 로고
    • Trans-10, cis-12 CLA increases liver and decreases adipose tissue lipids in mice: Possible roles of specific lipid metabolism genes
    • Warren JM, Simon VA, Bartolini G, Erickson KL, Mackey BE, Kelley DS: Trans-10, cis-12 CLA increases liver and decreases adipose tissue lipids in mice: possible roles of specific lipid metabolism genes. Lipids 2003;38:497-504.
    • (2003) Lipids , vol.38 , pp. 497-504
    • Warren, J.M.1    Simon, V.A.2    Bartolini, G.3    Erickson, K.L.4    Mackey, B.E.5    Kelley, D.S.6
  • 34
    • 0037426318 scopus 로고    scopus 로고
    • Activity and mRNA levels of enzymes involved in hepatic fatty acid synthesis and oxidation in mice fed conjugated linoleic acid
    • Takahashi Y, Kushiro M, Shinohara K, Ide T: Activity and mRNA levels of enzymes involved in hepatic fatty acid synthesis and oxidation in mice fed conjugated linoleic acid. Biochem Biophys Acta 2003;1631:265-273.
    • (2003) Biochem. Biophys. Acta. , vol.1631 , pp. 265-273
    • Takahashi, Y.1    Kushiro, M.2    Shinohara, K.3    Ide, T.4
  • 35
    • 0034693259 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
    • Osborne TF: Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action. J Biol Chem 2000;275:32379-32382.
    • (2000) J. Biol. Chem. , vol.275 , pp. 32379-32382
    • Osborne, T.F.1
  • 36
    • 0034804783 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Transcriptional regulators of lipid synthetic genes
    • Shimano H: Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes. Proc Lipid Res 2001;40:439-452.
    • (2001) Proc. Lipid Res. , vol.40 , pp. 439-452
    • Shimano, H.1
  • 37
    • 34247604581 scopus 로고    scopus 로고
    • TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-lc (SREBP-lc)
    • Endo M, Masaki T, Seike M, Yoshimatsu H: TNF-alpha induces hepatic steatosis in mice by enhancing gene expression of sterol regulatory element binding protein-lc (SREBP-lc). Exp Biol Med 2007;232:614-621.
    • (2007) Exp. Biol. Med. , vol.232 , pp. 614-621
    • Endo, M.1    Masaki, T.2    Seike, M.3    Yoshimatsu, H.4
  • 39
    • 36148934111 scopus 로고    scopus 로고
    • Slow absorption of conjugated linoleic acid in rat intestines, and similar absorption rates of 9c, 11t-conjugated linoleic acid and 10t, 12c-conjugated linoleic acid
    • Tsuzuki T, Ikeda I: Slow absorption of conjugated linoleic acid in rat intestines, and similar absorption rates of 9c, 11t-conjugated linoleic acid and 10t, 12c-conjugated linoleic acid. Biosci Biotechnol Biochem 2007;71:2034-2040.
    • (2007) Biosci Biotechnol. Biochem. , vol.71 , pp. 2034-2040
    • Tsuzuki, T.1    Ikeda, I.2
  • 40
    • 33846027504 scopus 로고    scopus 로고
    • Effects of cis-9, trans-11 and trans-10, cis-12 CLA isomers on liver and adipose tissue fatty acid profile in hamsters
    • Zabala A, Portillo MP, Macarulla MT, Rodriguez VM, Fernández- Quintela A: Effects of cis-9, trans-11 and trans-10, cis-12 CLA isomers on liver and adipose tissue fatty acid profile in hamsters. Lipids 2006;41:993-1001.
    • (2006) Lipids , vol.41 , pp. 993-1001
    • Zabala, A.1    Portillo, M.P.2    Macarulla, M.T.3    Rodriguez, V.M.4    Fernández-Quintela, A.5
  • 41
    • 33846603206 scopus 로고    scopus 로고
    • Intestinal bifidobacteria that produce trans-9, trans-11 conjugated linoleic acid: A fatty acid with antiproliferative activity against human colon SW480 and HT-29 cancer cells
    • Coakley M, Johnson MC, McGrath E, Rahman S, Ross RP, Fitzgerald GF, Devery R, Stanton C: Intestinal bifidobacteria that produce trans-9, trans-11 conjugated linoleic acid: a fatty acid with antiproliferative activity against human colon SW480 and HT-29 cancer cells. Nutr Cancer 2006;56:95-102.
    • (2006) Nutr Cancer , vol.56 , pp. 95-102
    • Coakley, M.1    Johnson, M.C.2    McGrath, E.3    Rahman, S.4    Ross, R.P.5    Fitzgerald, G.F.6    Devery, R.7    Stanton, C.8
  • 42
    • 19244381422 scopus 로고    scopus 로고
    • Geometry of conjugated double bonds of CLA isomers in a commercial mixture and in their hepatic 20:4 metabolites
    • Sébédio JL, Juanéda P, Grégoire S, Chardigny JM, Martin JC, Ginies C: Geometry of conjugated double bonds of CLA isomers in a commercial mixture and in their hepatic 20:4 metabolites. Lipids 1999;34:1319-1325.
    • (1999) Lipids , vol.34 , pp. 1319-1325
    • Sébédio, J.L.1    Juanéda, P.2    Grégoire, S.3    Chardigny, J.M.4    Martin, J.C.5    Ginies, C.6
  • 44
    • 28444481355 scopus 로고    scopus 로고
    • Detection of conjugated dienoic fatty acids in human vascular smooth muscle cells treated with conjugated linoleic acid
    • Muller A, Ringseis R, Dusterloh K, Gahler S, Eder K, Steinhart H: Detection of conjugated dienoic fatty acids in human vascular smooth muscle cells treated with conjugated linoleic acid. Biochim Biophys Acta 2005;1737:145-151.
    • (2005) Biochim Biophys. Acta. , vol.1737 , pp. 145-151
    • Muller, A.1    Ringseis, R.2    Dusterloh, K.3    Gahler, S.4    Eder, K.5    Steinhart, H.6
  • 45
    • 0346494715 scopus 로고    scopus 로고
    • Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: Regulation by alpha-tocopherol and cyclo-oxygenase-2 inhibitor
    • Smedman A, Vessby B, Basu S: Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: regulation by alpha-tocopherol and cyclo-oxygenase-2 inhibitor. Clin Sci (Lond) 2004;106:67-73.
    • (2004) Clin. Sci. (Lond) , vol.106 , pp. 67-73
    • Smedman, A.1    Vessby, B.2    Basu, S.3
  • 47
    • 0033868038 scopus 로고    scopus 로고
    • Conjugated linoleic acid supplementation in humans: Effects on body composition and energy expenditure
    • Zambell KL, Keim NL, Van Loan MD, Gale B, Benito P, Kelley DS, Nelson GJ: Conjugated linoleic acid supplementation in humans: effects on body composition and energy expenditure. Lipids 2000;35:777-782.
    • (2000) Lipids , vol.35 , pp. 777-782
    • Zambell, K.L.1    Keim, N.L.2    Van Loan, M.D.3    Gale, B.4    Benito, P.5    Kelley, D.S.6    Nelson, G.J.7
  • 49
    • 0038681580 scopus 로고    scopus 로고
    • The effect of conjugated linoleic acid supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects
    • Kamphius MM, Lejeune MP, Saris WH, Westerterp-Plantenga MS: The effect of conjugated linoleic acid supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects. Int J Obes 2003;27:840-847.
    • (2003) Int. J. Obes. , vol.27 , pp. 840-847
    • Kamphius, M.M.1    Lejeune, M.P.2    Saris, W.H.3    Westerterp-Plantenga, M.S.4
  • 50
    • 0038647713 scopus 로고    scopus 로고
    • Modulation of body composition and immune cell functions by conjugated linoleic acid in humans and animal models: Benefits vs. risks
    • Kelley DS, Erickson KL: Modulation of body composition and immune cell functions by conjugated linoleic acid in humans and animal models: Benefits vs. risks. Lipids 2003;38:377-386.
    • (2003) Lipids , vol.38 , pp. 377-386
    • Kelley, D.S.1    Erickson, K.L.2
  • 52
    • 33645633309 scopus 로고    scopus 로고
    • Conjugated linoleic acid supplementation for 1 year does not prevent weight or body fat regain
    • Larsen TM, Toubro S, Gudmundsen O, Astrup A: Conjugated linoleic acid supplementation for 1 year does not prevent weight or body fat regain. Am J Clin Nutr 2006;83:606-612.
    • (2006) Am. J. Clin. Nutr. , vol.83 , pp. 606-612
    • Larsen, T.M.1    Toubro, S.2    Gudmundsen, O.3    Astrup, A.4
  • 53
    • 47349118803 scopus 로고    scopus 로고
    • Conjugated linoleic acids: Why the discrepancy between animal and human studies?
    • Plourde M, Jew S, Cunnane SC, Jones PJ: Conjugated linoleic acids: why the discrepancy between animal and human studies? Nutr Rev 2008;66:415-421.
    • (2008) Nutr Rev. , vol.66 , pp. 415-421
    • Plourde, M.1    Jew, S.2    Cunnane, S.C.3    Jones, P.J.4
  • 55
    • 0036277054 scopus 로고    scopus 로고
    • Trans-10, cis-12 conjugated linoleic acid suppresses the desaturation of linoleic and alpha-linolenic acids in HepG2 cells
    • Eder K, Slomma N, Becker K: Trans-10, cis-12 conjugated linoleic acid suppresses the desaturation of linoleic and alpha-linolenic acids in HepG2 cells. J Nutr 2002;132:1115-1121.
    • (2002) J. Nutr. , vol.132 , pp. 1115-1121
    • Eder, K.1    Slomma, N.2    Becker, K.3
  • 56
    • 7044247355 scopus 로고    scopus 로고
    • The effects of ds-9, trans-ll and trans-10, ds-12 conjugated linoleic acids on delta4-desaturation in HepG2 cells
    • Slomma N, Becker K, Eder K: The effects of ds-9, trans-ll and trans-10, ds-12 conjugated linoleic acids on delta4-desaturation in HepG2 cells. Int J Vitam Nutr Res 2004;74:243-246.
    • (2004) Int. J. Vitam Nutr Res. , vol.74 , pp. 243-246
    • Slomma, N.1    Becker, K.2    Eder, K.3
  • 57
    • 67649443913 scopus 로고    scopus 로고
    • Arachidonic acid prevents fatty liver induced by conjugated linoleic acid in mice
    • Oikawa D, Tsuyama S, Akimoto Y, Mizobe Y, Furuse M: Arachidonic acid prevents fatty liver induced by conjugated linoleic acid in mice. Br J Nutr 2009;101:1558-1563.
    • (2009) Br. J. Nutr. , vol.101 , pp. 1558-1563
    • Oikawa, D.1    Tsuyama, S.2    Akimoto, Y.3    Mizobe, Y.4    Furuse, M.5
  • 58
    • 1242340451 scopus 로고    scopus 로고
    • Evidence that the anti-obesity effect of conjugated linoleic acid is independent of effects of stearoyl-CoA desaturasel expression and enzyme activity
    • Kang K, Miyazaki M, Ntambi JM, Pariza MW: Evidence that the anti-obesity effect of conjugated linoleic acid is independent of effects of stearoyl-CoA desaturasel expression and enzyme activity. Biochem Biophys Res Commun 2004;315:532-537.
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 532-537
    • Kang, K.1    Miyazaki, M.2    Ntambi, J.M.3    Pariza, M.W.4
  • 59
    • 33750445601 scopus 로고    scopus 로고
    • Desaturation indices in liver, muscle, and bone of growing male and female mice fed trans-10, cis-l2 conjugated linoleic acid
    • Viswanadha S, McGilliard ML, Herbein JH: Desaturation indices in liver, muscle, and bone of growing male and female mice fed trans-10, cis-l2 conjugated linoleic acid. Lipids 2006;41:763-770.
    • (2006) Lipids , vol.41 , pp. 763-770
    • Viswanadha, S.1    McGilliard, M.L.2    Herbein, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.