β,β-Dimethylacrylshikonin exerts antitumor activity via Notch-1 signaling pathway in vitro and in vivo

Biochemical Pharmacology

Volumn 84, Issue 4, 2012, Pages 507-512

  Zhen Jun, Shao ^a   Yuan Yuan, Zhang ^a   Ying Ying, Fan ^b   Shao Ju, Jin ^a,c   Jiao, Yan ^d   Xiao Wei, Zheng ^e   Jian, Chen ^a   Yao, Xiong ^a   Li Ming, Zhou ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c NINGXIA MEDICAL UNIVERSITY   (China)

^d Chengdu General Military Hospital   (China)

^e ZHEJIANG CANCER HOSPITAL   (China)

Author keywords

, Dimethylacrylshikonin; Gastric cancer; Notch 1

Indexed keywords

ANTINEOPLASTIC AGENT; BETA,BETA DIMETHYLACRYLSHIKONIN; CYCLOPHOSPHAMIDE; JAGGED1; NOTCH1 RECEPTOR; SHIKONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CELL ASSAY; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; COLONY FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STOMACH CANCER; TIME; TUMOR XENOGRAFT; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; DRUGS, CHINESE HERBAL; FEMALE; G0 PHASE; G1 PHASE; HUMANS; MICE; MICE, INBRED BALB C; NAPHTHOQUINONES; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84864128355     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.05.013     Document Type: Article

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