Inhibitory effects of β,β-dimethylacrylshikonin on hepatocellular carcinoma in vitro and in vivo

Phytotherapy Research

Volumn 26, Issue 5, 2012, Pages 764-771

  Wu, Yi Ying ^a   Wan, Li Hong ^a   Zheng, Xiao Wei ^b   Shao, Zhen Jun ^a   Chen, Jian ^a   Chen, Xia Jing ^a   Liu, Li Tao ^a   Kuang, Wen Juan ^a   Tan, Xian Shu ^a   Zhou, Li Ming ^a  

^a SICHUAN UNIVERSITY   (China)

^b ZHEJIANG CANCER HOSPITAL   (China)

Author keywords

, dimethylacrylshikonin; antitumor; apoptosis; H22; SMMC 7721

Indexed keywords

1,4 NAPHTHOQUINONE DERIVATIVE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANTINEOPLASTIC AGENT; BETA,BETA DIMETHYLACRYLSHIKONIN; CASPASE 3; CYCLOPHOSPHAMIDE; DNA NUCLEOTIDYLEXOTRANSFERASE; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG EFFICACY; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; NICK END LABELING; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; ANTHRAQUINONES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LITHOSPERMUM; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; NAPHTHOQUINONES; PLANT EXTRACTS; PLANT ROOTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER;

BORAGINACEAE; LITHOSPERMUM ERYTHRORHIZON;

EID: 84859883498     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3623     Document Type: Article

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