Novel cationic antimicrobial peptide GW-H1 induced caspase-dependent apoptosis of hepatocellular carcinoma cell lines

Peptides

Volumn 36, Issue 2, 2012, Pages 257-265

  Chen, Yi Lin Sophia ^a   Li, Jun Hong ^a   Yu, Chao Yuan ^a   Lin, Ching Ju ^a   Chiu, Pai Hsuan ^a   Chen, Po Wen ^b   Lin, Chai Ching ^a   Chen, Wei Jung ^a  

^a NATIONAL ILAN UNIVERSITY   (Taiwan)

^b NURSING AND MANAGEMENT COLLEGE   (Taiwan)

Author keywords

Anticancer; Antimicrobial peptide; Apoptosis; Caspase; Hepatocellular carcinoma

Indexed keywords

ANTIMICROBIAL PEPTIDE GW A5; ANTIMICROBIAL PEPTIDE GW H1; ANTIMICROBIAL PEPTIDE GW Q3; ANTIMICROBIAL PEPTIDE GW Q4; ANTIMICROBIAL PEPTIDE GW Q6; ANTINEOPLASTIC AGENT; CASPASE; CASPASE 3; CASPASE 7; CASPASE 9; HEAT SHOCK PROTEIN 27; MAGAININ 1; MAGAININ 2 AMIDE; PHOPHOGLYCERATE KINASE 1; PHOSPHOTRANSFERASE; PLEUROCIDIN; PLEUROCIDIN AMIDE; POLYPEPTIDE ANTIBIOTIC AGENT; PROCASPASE 3; TRIOSEPHOSPHATE ISOMERASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOMA CELL; CELL CYCLE G1 PHASE; CELL MEMBRANE; CELL NUCLEUS; CELL ORGANELLE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; DRUG DESIGN; DRUG EFFECT; ENZYME ACTIVATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIVER CELL CARCINOMA; MASS SPECTROMETRY; METASTASIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CASPASES; CELL CYCLE; CELL LINE; CELL LINE, TUMOR; CELL SURVIVAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FLOW CYTOMETRY; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, NUDE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

BACTERIA (MICROORGANISMS); MUS MUSCULUS;

EID: 84864125700     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.05.011     Document Type: Article

References (40)

1. J. Ai, H. Huang, X. Lv, Z. Tang, M. Chen, and T. Chen FLNA and PGK1 are two potential markers for progression in hepatocellular carcinoma Cell Physiol Biochem 27 2011 207 216
2. D. Andreu, and L. Rivas Animal antimicrobial peptides: an overview Biopolymers 47 1998 415 433
3. M.A. Baker, W.L. Maloy, M. Zasloff, and L.S. Jacob Anticancer efficacy of magainin 2 and analogue peptides Cancer Res 53 1993 3052 3057
4. W.T. Chang, C.Y. Pan, V. Rajanbabu, C.W. Cheng, and J.Y. Chen Tilapia (Oreochromis mossambicus) antimicrobial peptide, hepcidin 1-5, shows antitumor activity in cancer cells Peptides 32 2011 342 352
5. H.M. Chen, W. Wang, D. Smith, and S.C. Chan Effects of the anti-bacterial peptide cecropin B and its analogs, cecropins B-1 and B-2, on liposomes, bacteria, and cancer cells Biochim Biophys Acta 1336 1997 171 179
6. J.Y. Chen, W.J. Lin, and T.L. Lin A fish antimicrobial peptide, tilapia hepcidin TH2-3, shows potent antitumor activity against human fibrosarcoma cells Peptides 30 2009 1636 1642
7. H.T. Chou, T.Y. Kuo, J.C. Chiang, M.J. Pei, W.T. Yang, and H.C. Yu Design and synthesis of cationic antimicrobial peptides with improved activity and selectivity against Vibrio spp Int J Antimicrob Agents 32 2008 130 138
8. H.T. Chou, H.W. Wen, T.Y. Kuo, C.C. Lin, and W.J. Chen Interaction of cationic antimicrobial peptides with phospholipid vesicles and their antibacterial activity Peptides 31 2010 1811 1820
9. C.G. Concannon, A.M. Gorman, and A. Samali On the role of Hsp27 in regulating apoptosis Apoptosis 8 2003 61 70
10. C.G. Concannon, S. Orrenius, and A. Samali Hsp27 inhibits cytochrome c-mediated caspase activation by sequestering both pro-caspase-3 and cytochrome c Gene Expr 9 2001 195 201
11. R.A. Cruciani, J.L. Barker, M. Zasloff, H.C. Chen, and O. Colamonici Antibiotic magainins exert cytolytic activity against transformed cell lines through channel formation Proc Natl Acad Sci USA 88 1991 3792 3796
12. K. Daskalow, D. Pfander, W. Weichert, N. Rohwer, A. Thelen, and P. Neuhaus Distinct temporospatial expression patterns of glycolysis-related proteins in human hepatocellular carcinoma Histochem Cell Biol 132 2009 21 31
13. S.R. Dennison, M. Whittaker, F. Harris, and D.A. Phoenix Anticancer alpha-helical peptides and structure/function relationships underpinning their interactions with tumour cell membranes Curr Protein Pept Sci 7 2006 487 499
14. L.T. Eliassen, G. Berge, B. Sveinbjornsson, J.S. Svendsen, L.H. Vorland, and O. Rekdal Evidence for a direct antitumor mechanism of action of bovine lactoferricin Anticancer Res 22 2002 2703 2710
15. H.M. Ellerby, W. Arap, L.M. Ellerby, R. Kain, R. Andrusiak, and G.D. Rio Anti-cancer activity of targeted pro-apoptotic peptides Nat Med 5 1999 1032 1038
16. R.M. Epand, and H.J. Vogel Diversity of antimicrobial peptides and their mechanisms of action Biochim Biophys Acta 1462 1999 11 28
17. K. Guo, N.X. Kang, Y. Li, L. Sun, L. Gan, and F.J. Cui Regulation of HSP27 on NF-kappaB pathway activation may be involved in metastatic hepatocellular carcinoma cells apoptosis BMC Cancer 9 2009 100
18. J.C. Hsu, L.C. Lin, J.T. Tzen, and J.Y. Chen Pardaxin-induced apoptosis enhances antitumor activity in HeLa cells Peptides 32 2011 1110 1116
19. J.C. Hsu, L.C. Lin, J.T. Tzen, and J.Y. Chen Characteristics of the antitumor activities in tumor cells and modulation of the inflammatory response in RAW264.7 cells of a novel antimicrobial peptide, chrysophsin-1, from the red sea bream (Chrysophrys major) Peptides 32 2011 900 910
20. T.C. Huang, J.F. Lee, and J.Y. Chen Pardaxin, an antimicrobial peptide, triggers caspase-dependent and ROS-mediated apoptosis in HT-1080 cells Mar Drugs 9 2011 1995 2009
21. S.A. Johnstone, K. Gelmon, L.D. Mayer, R.E. Hancock, and M.B. Bally In vitro characterization of the anticancer activity of membrane-active cationic peptides: I. Peptide-mediated cytotoxicity and peptide-enhanced cytotoxic activity of doxorubicin against wild-type and p-glycoprotein over-expressing tumor cell lines Anticancer Drug Des 15 2000 151 154
22. D.Y. Kao, Y.C. Cheng, T.Y. Kuo, S.B. Lin, C.C. Lin, and L.P. Chow Salt-responsive outer membrane proteins of Vibrio anguillarum serotype O1 as revealed by comparative proteome analysis J Appl Microbiol 106 2009 2079 2085
23. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
24. I.N. Lee, C.H. Chen, J.C. Sheu, H.S. Lee, G.T. Huang, and C.Y. Yu Identification of human hepatocellular carcinoma-related biomarkers by two-dimensional difference gel electrophoresis and mass spectrometry J Proteome Res 4 2005 2062 2069
25. L. Li, S.H. Chen, C.H. Yu, Y.M. Li, and S.Q. Wang Identification of hepatocellular-carcinoma-associated antigens and autoantibodies by serological proteome analysis combined with protein microarray J Proteome Res 7 2008 611 620
26. M.C. Lin, S.B. Lin, J.C. Chen, C.F. Hui, and J.Y. Chen Shrimp anti-lipopolysaccharide factor peptide enhances the antitumor activity of cisplatin in vitro and inhibits HeLa cells growth in nude mice Peptides 31 2010 1019 1025
27. M.C. Lin, S.B. Lin, S.C. Lee, C.C. Lin, C.F. Hui, and J.Y. Chen Antimicrobial peptide of an anti-lipopolysaccharide factor modulates of the inflammatory response in RAW264.7 cells Peptides 31 2010 1262 1272
28. W.J. Lin, Y.L. Chien, C.Y. Pan, T.L. Lin, J.Y. Chen, and S.J. Chiu Epinecidin-1, an antimicrobial peptide from fish (Epinephelus coioides) which has an antitumor effect like lytic peptides in human fibrosarcoma cells Peptides 30 2009 283 290
29. J.C. Mai, Z. Mi, S.H. Kim, B. Ng, and P.D. Robbins A proapoptotic peptide for the treatment of solid tumors Cancer Res 61 2001 7709 7712
30. R. Matsushima-Nishiwaki, S. Takai, S. Adachi, C. Minamitani, E. Yasuda, and T. Noda Phosphorylated heat shock protein 27 represses growth of hepatocellular carcinoma via inhibition of extracellular signal-regulated kinase J Biol Chem 283 2008 18852 18860
31. K. Matsuzaki, K. Sugishita, N. Ishibe, M. Ueha, S. Nakata, and K. Miyajima Relationship of membrane curvature to the formation of pores by magainin 2 Biochemistry 37 1998 11856 11863
32. P.H. O'Farrell High resolution two-dimensional electrophoresis of proteins J Biol Chem 250 1975 4007 4021
33. Y. Ohsaki, A.F. Gazdar, H.C. Chen, and B.E. Johnson Antitumor activity of magainin analogues against human lung cancer cell lines Cancer Res 52 1992 3534 3538
34. N. Papo, M. Shahar, L. Eisenbach, and Y. Shai A novel lytic peptide composed of dl-amino acids selectively kills cancer cells in culture and in mice J Biol Chem 278 2003 21018 21023
35. S. Riedl, D. Zweytick, and K. Lohner Membrane-active host defense peptides - challenges and perspectives for the development of novel anticancer drugs Chem Phys Lipids 164 2011 766 781
36. N. Sitaram, and R. Nagaraj Interaction of antimicrobial peptides with biological and model membranes: structural and charge requirements for activity Biochim Biophys Acta 1462 1999 29 54
37. T. Utsugi, A.J. Schroit, J. Connor, C.D. Bucana, and I.J. Fidler Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes Cancer Res 51 1991 3062 3066
38. N. Yang, T. Lejon, and O. Rekdal Antitumor activity and specificity as a function of substitutions in the lipophilic sector of helical lactoferrinderived peptides J Pept Sci 9 2003 300 311
39. N. Yang, W. Stensen, J.S. Svendesen, and O. Rekdal Enhanced antitumor activity and selectivity of lactoferrin-derived peptides J Pept Res 60 2002 187 197
40. Y.L. Yu, S.L. Yu, K.J. Su, C.W. Wei, M.H. Jian, and P.C. Lin Extended O6-methylguanine methyltransferase promoter hypermethylation following n-butylidenephthalide combined with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) on inhibition of human hepatocellular carcinoma cell growth J Agric Food Chem 58 2010 1630 1638