Phosphorylated heat shock protein 27 represses growth of hepatocellular carcinoma via inhibition of extracellular signal-regulated kinase

Journal of Biological Chemistry

Volumn 283, Issue 27, 2008, Pages 18852-18860

  Matsushima Nishiwaki, Rie ^a   Takai, Shinji ^a   Adachi, Seiji ^a   Minamitani, Chiho ^a   Yasuda, Eisuke ^a,b   Noda, Takahiro ^a,b   Kato, Kanefusa ^c   Toyoda, Hidenori ^b   Kaneoka, Yuji ^b   Yamaguchi, Akihiro ^b   Kumada, Takashi ^b   Kozawa, Osamu ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OGAKI MUNICIPAL HOSPITAL   (Japan)

^c INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL GROWTH; CHEMICAL ACTIVATION; ENZYME ACTIVITY; GROWTH (MATERIALS); GROWTH KINETICS; PHOSPHORYLATION;

ACTIVATED PROTEIN KINASES; ACTIVATOR PROTEINS; EXTRACELLULAR SIGNALS; HEAT SHOCK PROTEINS; HEPATOCARCINOGENESIS; HEPATOCELLULAR CARCINOMA CELLS; HEPATOCELLULAR CARCINOMATA; HUH7 CELLS; IN-VIVO; INHIBITORY PROTEINS; MITOGEN; MOLECULAR CHAPERONES; PROINFLAMMATORY CYTOKINE; REGULATED KINASES; SIGNAL PATHWAYS; STRESS PROTEINS; SUSTAINED ACTIVATIONS; TRANSACTIVATION; TUMOR NECROSIS FACTORS;

PROTEINS;

CASPASE 9; CYCLIN D1; CYTOKINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; RAF PROTEIN; SERINE; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; CYCLIN D; CYCLINE; HEAT SHOCK PROTEIN; HSPB1 PROTEIN, HUMAN; TUMOR PROTEIN;

ARTICLE; CANCER INHIBITION; CANCER RECURRENCE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; UPREGULATION; ENZYMOLOGY; GENETICS; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CYCLINS; DUAL SPECIFICITY PHOSPHATASE 1; HEAT-SHOCK PROTEINS; HUMANS; MAP KINASE SIGNALING SYSTEM; NEOPLASM PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RAF KINASES; TRANSCRIPTION FACTOR AP-1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 49649086083     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801301200     Document Type: Article

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