Prognostic significance of APE1 cytoplasmic localization in human epithelial ovarian cancer

Medical Oncology

Volumn 29, Issue 2, 2012, Pages 1265-1271

  Sheng, Qingsong ^a   Zhang, Ying ^a   Wang, Rui ^b   Zhang, Jianfang ^a   Chen, Biliang ^a   Wang, Jian ^a   Zhang, Wei ^b   Xin, Xiaoyan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apurinic Apyrimidinic endonuclease; Cytoplasmic localization; Epithelial ovarian cancer; Immunohistochemistry; Prognosis

Indexed keywords

REDOX EFFECTOR FACTOR 1; APEX1 PROTEIN, HUMAN; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE;

ADULT; AGED; ARTICLE; ASCITES; CANCER GROWTH; CANCER PATIENT; CANCER PROGNOSIS; CANCER STAGING; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; ENZYME LOCALIZATION; FAMILY HISTORY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; OVARY CARCINOMA; PRIORITY JOURNAL; SURVIVAL RATE; TUMOR DIFFERENTIATION; TUMOR VOLUME; CYSTADENOCARCINOMA; ENDOMETRIUM TUMOR; ENZYME IMMUNOASSAY; METABOLISM; MIDDLE AGED; MORTALITY; OVARY TUMOR; PROGNOSIS;

CYSTADENOCARCINOMA, MUCINOUS; CYSTADENOCARCINOMA, SEROUS; CYTOPLASM; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHATIC METASTASIS; MIDDLE AGED; NEOPLASM STAGING; OVARIAN NEOPLASMS; PROGNOSIS; SURVIVAL RATE;

EID: 84864094351     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-011-9931-y     Document Type: Article

References (35)

1. Auersperg N, Wong AS, Choi KC, et al. Ovarian surface epithelium: biology, endocrinology, and pathology. Endocr Rev. 2001;22(2):255-88.
2. Cheng X, Young TW, Mei FC. Proteomics analyses of ovarian cancer using genetically defined human ovarian cancer models. Front Biosci. 2007;125:166-74.
3. Jemal A, Thomas A, Murray T, et al. Cancer statistics, 2002. CA Cancer J Clin. 2002;52(1):23-47.
4. Dianov GL, Sleeth KM, Dianova II, et al. Repair of abasic sites in DNA. Mutat Res. 2003;531(1-2):157-63.
5. Diamond DA, Parsian A, Hunt CR, et al. Redox factor-1 (Ref-1) mediates the activation of AP-1 in HeLa and NIH 3T3 cells in response to heat shock. J Biol Chem. 1999;274(24):16959-64.
6. Hirota K, Matsui M, Iwata S, et al. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc Natl Acad Sci USA. 1997;94(8):3633-8.
7. Tell G, Damante G, Caldwell D, et al. The intracellular localization of APE1/Ref-1: more than a passive phenomenon? Antioxid Redox Signal. 2005;7(3-4):367-84.
8. Evans AR, Limp-Foster M, Kelley MR. Going APE over ref-1. Mutat Res. 2000;461(2):83-108.
9. Noike T, Miwa S, Soeda J, et al. Increased expression of thioredoxin- 1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer. Hum Pathol. 2008;39(2):201-8.
10. Kakolyris S, Kaklamanis L, Engels K, et al. Human AP endonuclease 1 (HAP1) protein expression in breast cancer correlates with lymph node status and angiogenesis. Br J Cancer. 1998; 77(7):1169-73.
11. Qing Y, Wang D, Lei X, et al. The expression of APE1 and its correlation with prognostic significance after 252Cf radiotherapy in cervical cancer. Sichuan Da Xue Xue Bao Yi Xue Ban. 2009; 40(1):125-8.
12. Di Maso V, Avellini C, Croce LS, et al. Subcellular localization of APE1/Ref-1 in human hepatocellular carcinoma: possible prognostic significance. Mol Med. 2007;13(1-2):89-96.
13. Puglisi F, Aprile G, Minisini AM, et al. Prognostic significance of Ape1/ref-1 subcellular localization in non-small cell lung carcinomas. Anticancer Res. 2001;21(6A):4041-9.
14. Al-Attar A, Gossage L, Fareed KR, et al. Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancers. Br J Cancer. 2010;102(4):704-9.
15. Russo D, Arturi F, Bulotta S, et al. ApeI/Ref-I expression and cellular localization in human thyroid carcinoma cell lines. J Endocrinol Invest. 2001;24(3):RC10-2.
16. Puglisi F, Barbone F, Tell G, et al. Prognostic role of Ape/Ref-1 subcellular expression in stage I-III breast carcinomas. Oncol Rep. 2002;9(1):11-7.
17. Zhang Y, Wang J, Xiang D, et al. Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE1/Ref-1) in human ovarian cancer and indentification of the therapeutic potential of APE1/Ref-1 inhibitor. Int J Oncol. 2009;35(5): 1069-79.
18. Tell G, Fantini D, Quadrifoglio F. Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment. Cell Mol Life Sci. 2010;67(21): 3589-608.
19. Abbotts R, Madhusudan S. Human AP endonuclease 1 (APE1): from mechanistic insights to druggable target in cancer. Cancer Treat Rev. 2010;36(5):425-35.
20. Bisetto E, Domenis R, Comelli M, et al. New insights in the mitochondrial localization of APE1, the major apurinic/apyrimidinic endonuclease in mammals. Biochim Biophys Acta. 2010; 179771-2.
21. Tell G, Quadrifoglio F, Tiribelli C, et al. The many functions of APE1/Ref-1: not only a DNA repair enzyme. Antioxid Redox Signal. 2009;11(3):601-20.
22. Izumi T, Brown DB, Naidu CV, et al. Two essential but distinct functions of the mammalian abasic endonuclease. Proc Nat Acad Sci USA. 2005;102(16):5739-43.
23. Yang S, Irani K, Chun S, et al. Expression of apurinic/apyrymidinic endonuclease/redox effector-1 (APE/Ref-1) is elevated with progression of human melanoma and the therapeutic potential of APE/Ref-1 inhibitors. Proc Am Assoc Cancer Res. 2005;2005(1):1043.
24. Bobola MS, Emond MJ, Blank A, et al. Apurinic endonuclease activity in adult gliomas and time to tumor progression after alkylating agent-based chemotherapy and after radiotherapy. Clin Cancer Res. 2004;10(23):7875-83.
25. Daily D, Vlamis-Gardikas A, Offen D, et al. Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by activating NF-kappa B via Ref-1. J Biol Chem. 2001;276(2): 1335-44.
26. Grösch S, Kaina B. Transcriptional activation of apurinic/apyrimidinic endonuclease (Ape, Ref-1) by oxidative stress requires CREB. Biochem Biophys Res Commun. 1999;261(3): 859-63.
27. Kasahara T, Kuwayama C, Hashiba M, et al. The gene expression of hepatic proteins responsible for DNA repair and cell proliferation in tamoxifen-induced hepatocarcinogenesis. Cancer Sci. 2003;94(7):582-8.
28. Tell G, Crivellato E, Pines A, et al. Mitochondrial localization of APE/Ref-1 in thyroid cells. Mutat Res. 2001;485(2):143-52.
29. Fung H, Kow YW, Van Houten B, et al. Asbestos increases mammalian AP-endonuclease gene expression, protein levels, and enzyme activity in mesothelial cells. Cancer Res. 1998;58(2): 189-94.
30. Fan Z, Beresford PJ, Zhang D, et al. Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A. Nat Immunol. 2003;4(2):145-53.
31. Fan Z, Beresford PJ, Zhang D, et al. HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A. Mol Cell Biol. 2002;22(8): 2810-20.
32. Duguid JR, Eble JN, Wilson TM, et al. Differential cellular and subcellular expression of the human multifunctional apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme. Cancer Res. 1995;55(24):6097-102.
33. Barnes T, Kim WC, Mantha AK, et al. Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA. Nucleic Acids Res. 2009;37(12):3946-58.
34. Vascotto C, Fantini D, Romanello M, et al. APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process. Mol Cell Biol. 2009;29(7):1834-54.
35. Tell G, Wilson DM 3rd, Lee CH. Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era? Mol Cell Biol. 2010;30(2):366-71.