Metabolomic analysis of the toxic effect of chronic low-dose exposure to acephate on rats using ultra-performance liquid chromatography/mass spectrometry

Ecotoxicology and Environmental Safety

Volumn 83, Issue , 2012, Pages 25-33

  Hao, Dong Fang ^a   Xu, Wei ^a   Wang, Hong ^a   Du, Long Fei ^a   Yang, Jin Dan ^a   Zhao, Xiu Juan ^a   Sun, Chang Hao ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Acephate; Chronic exposure; Low dose; Metabolomics; Toxicity; UPLC MS

Indexed keywords

ACEPHATE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE;

BIOMARKER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLITE; ORGANOPHOSPHATE; RODENT; TOXICITY; URINE;

ACCURACY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHEMICAL ANALYSIS; CONTROLLED STUDY; GLUCOSE METABOLISM; HISTOPATHOLOGY; KIDNEY INJURY; LONG TERM EXPOSURE; MALE; MASS SPECTROMETRY; METABOLOMICS; NONHUMAN; NUCLEIC ACID METABOLISM; PROTEIN METABOLISM; RAT; TOXICITY TESTING; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UREA NITROGEN BLOOD LEVEL; URINALYSIS;

ANIMALS; BIOLOGICAL MARKERS; CHROMATOGRAPHY, LIQUID; ENVIRONMENTAL POLLUTANTS; MALE; MASS SPECTROMETRY; METABOLISM; METABOLOME; METABOLOMICS; ORGANOTHIOPHOSPHORUS COMPOUNDS; PHOSPHATES; PHOSPHORAMIDES; RATS; RATS, WISTAR;

EID: 84864089837     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2012.06.006     Document Type: Article

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