Humans appear no more sensitive than laboratory animals to the inhibition of red blood cell cholinesterase by dichlorvos

Regulatory Toxicology and Pharmacology

Volumn 43, Issue 2, 2005, Pages 150-167

  MacGregor, Judith A ^a   Plunkett, Laura M ^b   Youngren, Susan Hunter ^c   Manley, Ann ^d   Plunkett, James Barry ^b   Starr, Thomas B ^e  

^a Toxicology Consulting Services   (United States)

^b Integrative Biostrategies   (United States)

^c LLC   (United States)

^d Amvac Chemical Corporation   (United States)

^e TBS Associates   (United States)

Author keywords

Dichlorvos; Interspecies uncertainty factor; Red blood cell cholinesterase; Reference dose (RfD)

Indexed keywords

ACETYLCHOLINESTERASE; DICHLORVOS;

ACCURACY; ARTICLE; CLINICAL TRIAL; DOG; DOSE RESPONSE; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG MEGADOSE; DRUG METABOLISM; DRUG SAFETY; ENZYME INHIBITION; HUMAN; LOW DRUG DOSE; MONKEY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RISK ASSESSMENT; SPECIES DIFFERENCE; TOXICOLOGY;

ALGORITHMS; ANIMALS; BODY WEIGHT; CHOLINESTERASE INHIBITORS; DICHLORVOS; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; FEMALE; HAPLORHINI; HUMANS; INHALATION EXPOSURE; MALE; PREGNANCY; RATS; SPECIES SPECIFICITY;

ANIMALIA; CANIS FAMILIARIS; RATTUS NORVEGICUS;

EID: 26444490621     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2005.06.013     Document Type: Article

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