Arctigenin promotes degradation of inducible nitric oxide synthase through CHIP-associated proteasome pathway and suppresses its enzyme activity

International Immunopharmacology

Volumn 14, Issue 2, 2012, Pages 138-144

  Yao, Xiangyang ^a   Li, Guilan ^b   Lü, Chaotian ^a   Xu, Hui ^a   Yin, Zhimin ^b  

^a BENGBU COLLEGE   (China)

^b NANJING NORMAL UNIVERSITY   (China)

Author keywords

Arctigenin; Carboxyl terminus of HSC70 interacting protein (CHIP); Inducible nitric oxide synthase (iNOS); Lipopolysaccharide (LPS); Phosphorylation; Ubiquitination

Indexed keywords

ARCTIGENIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; PROTEASOME;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT; UBIQUITINATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL LINE; ENZYME ACTIVATION; FURANS; HUMANS; LIGNANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84864075049     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.06.017     Document Type: Article

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