Model-based characterization of operational stability of multimeric enzymes with complex deactivation behavior: An in-silico investigation

Chemical Engineering Science

Volumn 80, Issue , 2012, Pages 435-450

  Bechtold, Matthias ^a   Panke, Sven ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Biocatalysis; Biocatalyst operational stability; Catalyst deactivation; Model based experimental analysis; Parameter identification; T ramping

Indexed keywords

BIOCATALYSIS; BIOTRANSFORMATION PROCESS; CHARACTERIZATION METHODS; CONTINUOUS REACTOR OPERATION; CONTINUOUS REACTORS; DEACTIVATION MECHANISM; DEGRADATION PATHWAYS; DESIGN TASKS; DIMERIC ENZYME; DIMERIC MODELS; ERROR DATA; EXPERIMENTAL PROCEDURE; IN-SILICO; INPUT DATAS; LACK-OF-FIT; MECHANISTIC MODELS; MODEL-BASED EXPERIMENTAL ANALYSIS; MODELING STUDIES; MULTIMERIC ENZYMES; OPERATIONAL STABILITY; PARAMETERIZATIONS; PROCESS CONDITION; PROCESS PREDICTION; PROGRESS CURVES; SUBUNIT DISSOCIATION; T-RAMPING; VIRTUAL PROCESS;

BIOCATALYSTS; CATALYST DEACTIVATION; CHARACTERIZATION; DEGRADATION; ENZYME KINETICS; FORECASTING; IDENTIFICATION (CONTROL SYSTEMS); INPUT OUTPUT PROGRAMS; PARAMETER ESTIMATION; PARAMETERIZATION; PROCESS DESIGN; REACTOR OPERATION;

STABILITY;

EID: 84864058997     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2012.05.030     Document Type: Article

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