Accelerated biocatalyst stability testing for process optimization

Biotechnology Progress

Volumn 21, Issue 3, 2005, Pages 762-774

  Gibbs, Phillip R ^a,b   Uehara, Christian S ^b   Neunert, Urban ^a,c   Bommarius, Andreas S ^a  

^a Georgia Institute of Technology   (United States)

^b Stheno Corporation   (United States)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST DEACTIVATION; GLUCOSE; OPTIMIZATION; PROTEINS; RATE CONSTANTS; THERMAL EFFECTS; THERMODYNAMICS;

CATALYTIC CONSTANTS; KINETIC CONSTANTS; TEMPERATURE DEPENDENCE; TRANSITION STATE THEORY;

BIOCATALYSTS;

FRUCTOSE; GLUCOSE; ISOMERASE; XYLOSE ISOMERASE;

ARTICLE; CATALYSIS; CHEMICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; COMPUTER SIMULATION; ENZYME ACTIVATION; ENZYME STABILITY; EVALUATION; KINETICS; SYNTHESIS;

ALDOSE-KETOSE ISOMERASES; CATALYSIS; COMPUTER SIMULATION; ENZYME ACTIVATION; ENZYME STABILITY; FRUCTOSE; GLUCOSE; KINETICS; MODELS, CHEMICAL;

EID: 20144365371     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp049609k     Document Type: Article

References (49)

1. Rozzell, J. D. Commercial scale biocatalysis: myths and realities. Bioorg. Med. Chem. 1999, 7 (10), 2253-2261.
2. Bommarius, A. S.; Estler, M.; Kluge, A.; Werner, H.; Vollmer, H.; Bock, H. G.; Schlöder, J.; Kostina, E. Multistep method for the determination of enzyme process stability. Patent application DE 199 30496, 2001.
3. Richardson, T. H.; Tan, X.; Frey, G.; Callen, W.; Cabell, M.; Lam, D.; Macomber, J.; Short, J. M.; Robertson, D. E.; Miller, C. A novel, high performance enzyme for starch liquefaction. Discovery and optimization of a low pH, thermostable alpha - amylase. J. Biol. Chem. 2002, 277 (29), 26501-26507.
4. O'Fagain, C. Enzyme stabilization-recent experimental progress. Enzyme Microb. Technol. 2003, 33 (2-3), 137-149.
5. Bandlish, R. K.; Hess, J. M.; Epting, K. L.; Vieille, C.; Kelly, R. M. Glucose-to-fructose conversion at high temperatures with xylose (glucose) isomerases from Streptomyces murinus and two hyperthermophilic Thermotoga species. Biotechnol. Bioeng. 2002, 80 (2), 185-194.
6. Boy, M.; Dominik, A.; Voss, H. Fast determination of biocatalyst process stability. Process Biochem. 1999, 34 (6-7), 535-547.
7. Bhosale, S. H.; Rao, M. B.; Deshpande, V. V. Molecular and industrial aspects of glucose isomerase. Microbiol. Rev. 1996, 60 (2), 280-300.
8. Asboth, B.; Naray-Szabo, G. Mechanism of Action of D-Xylose Isomerase. Curr. Protein Pept. Sci. 2000, 1 (3), 237-254.
9. Wingard, L. B.; Katzir, E.; Goldstein, L. Enzyme Technology; Academic Press: New York, 1979.
10. Gerhartz, W. Enzymes in Industry: Production and Applications; VCH: New York, 1990.
11. Crabb, W. D.; Shetty, J. K. Commodity scale production of sugars from starches. Curr. Opin. Microbiol. 1999, 2 (3), 252-256.
12. Crabb, W. D.; Mitchinson, C. Enzymes involved in the processing of starch to sugars. Trends Biotechnol. 1997, 15 (9), 349-352.
13. Faqir, N. M.; Attarakih, M. M. Optimal temperature policy for immobilized enzyme packed bed reactor performing reversible Michaelis-Menten kinetics using the disjoint policy. Biotechnol. Bioeng. 2002, 77 (2), 163-173.
14. Faqir, N. M. Optimization of operating temperature for an continuous immobilized glucose isomerase reactor with pseudolinear kinetics. Eng. Life Sci. 2004, 4 (5), 450-459.
15. Converti, A.; Fisichella, A.; Riscolo, A.; Borghi, M. D.; Scaringi, A.; Carbone, D. Simulation of a reactor for glucose isomerization to fructose by immobilized glucose isomerase with continuous enzyme renewal. Biotechnol. Tech. 1997, 11, (2), 99-103.
16. Genencor, Product Information Gensweet IGI-SA; Genencor International: Rochester, NY, 2001.
17. Converti, A.; Borghi, M. D. Kinetics of glucose isomerization to fructose by immobilized glucose isomerase in the presence of substrate protection. Bioprocess Biosyst. Eng. 1997, 18 (1), 27-33.
18. Tewari, Y. B.; Goldberg, R. N. Thermodynamics of the conversion of aqueous glucose to fructose. J. Solution Chem. 1984, 13, 523-547.
19. Palazzi, E.; Converti, A. Evaluation of diffusional resistances in the process of glucose isomerization to fructose by immobilized glucose isomerase. Enzyme Microb. Technol. 2001, 28 (2-3), 246-252.
20. Palazzi, E.; Converti, A. Generalized linearization of kinetics of glucose isomerization to fructose by immobilized glucose isomerase. Biotechnol. Bioeng. 1999, 63 (3), 273-84.
21. Straatsma, J.; Vellenga, K.; Wilt, H. G. J. D.; Joosten, G. E. H. Isomerization of glucose to fructose. 1. The stability of a whole cell immobilized glucose isomerase catalyst. Ind. Eng. Chem. Process Des. Dev. 1983, 22 (3), 349-356.
22. Converti, A.; Del Borghi, M. Simultaneous effects of immobilization and substrate protection on the thermodynamics of glucose isomerase activity and inactivation. Enzyme Microb. Technol. 1997, 21 (7), 511-517.
23. Chen, L. F.; Gong, C. S.; Tsao, G. T. Immobilized glucose isomerase on DEAE cellulose beads. Starch/Staerke 1981, 33, 58-63.
24. Lee, Y. Y.; Fratzke, A. R.; Wun, K.; Tsao, G. T. Glucose isomerase immobilized on porous glass. Biotechnol. Bioeng. 1976, 18 (3), 389-413.
25. Nielsen, M. H.; Zittan, L.; Hemmingsen, S. H. In Industrial processes for the manufacture of high fructose corn syrups. In Chemical Engineering in a Changing World: Proceedings of the Plenary Sessions of the First World Congress on Chemical Engineering; Elsevier/North Holland: New York, 1976; pp 183-198.
26. Roels, J. A.; Tilberg, R. V. Temperature dependence of stability and activity of an immobilized glucose isomerase in a packed bed. Starch/Staerke 1979, 31, (17-24).
27. Illanes, A.; Wilson, L. Enzyme reactor design under thermal inactivation. Crit. Rev. Biotechnol. 2003, 23 (1), 61-93.
28. Vrabel, P.; Polakovic, M.; Stefuca, V.; Bales, V. Analysis of mechanism and kinetics of thermal inactivation of enzymes: Evaluation of multitemperature data applied to inactivation of yeast invertase. Enzyme Microb. Technol. 1997, 20 (5), 348-354.
29. Aymard, C.; Belarbi, A. Kinetics of thermal deactivation of enzymes: a simple three parameters phenomenological model can describe the decay of enzyme activity, irrespectively of the mechanism. Enzyme Microb. Technol. 2000, 27 (8), 612-618.
30. Lumry, R.; Eyring, H. Conformation changes of proteins. J. Phys. Chem. 1954, 58 (2), 110-120.
31. Peterson, M. E.; Eisenthal, R.; Danson, M. J.; Spence, A.; Daniel, R. M. A new intrinsic thermal parameter for enzymes reveals true temperature optima. J. Biol. Chem. 2004, 279 (20), 20717-20722.
32. Patnaik, P. R. Temperature optima of enzymes: sifting fact from fiction. Enzyme Microb. Technol. 2002, 31 (3), 198-200.
33. Daniel, R. M.; Danson, M. J.; Eisenthal, R. The temperature optima of enzymes: a new perspective on an old phenomenon. Trends Biochem. Sci. 2001, 26 (4), 223-5.
34. Polakovic, M.; Bryjak, J. Modelling of the kinetics of thermal inactivation of glucoamylase from Aspergillus niger. J. Mol. Catal. B: Enzym. 2002, 19-20, 443-450.
35. Illeova, V.; Polakovic, M.; Stefuca, V.; Acai, P.; Juma, M. Experimental modelling of thermal inactivation of urease. J. Biotechnol. 2003, 105 (3), 235-243.
36. Vrabel, P.; Polakovic, M.; Godo, S.; Bales, V.; Docolomansky, P.; Gemeiner, P. Influence of immobilization on the thermal inactivation of yeast invertase. Enzyme Microb. Technol. 1997, 21 (3), 196-202.
37. Murayama, S. 687 days is the record for Sweetzyme. Biotimes 1998, http://www.novozymes.com/cgi-bin/bvisapi.dll/biotimes/one_article.jsp?id= 11422&lang=en.
38. Seelbach, K.; Deurzen, M. P. J. v.; Rantwijk, F. v.; Sheldon, R. A.; Kragl, U. Improvement of the total turnover number and space-time yield for chloroperoxidase catalyzed oxidation. Biotechnol. Bioeng. 1997, 55 (2), 283-288.
39. Ahern, T. J.; Klibanov, A. M. Analysis of processes causing thermal inactivation of enzymes. Methods Biochem. Anal. 1988, 33, 91-127.
40. Volkin, D. B.; Klibanov, A. M. Mechanism of thermoinactivation of immobilized glucose isomerase. Biotechnol. Bioeng. 1989, 33 (9), 1104-1111.
41. Conway, M. E.; Poole, L. B.; Hutson, S. M. Roles for cysteine residues in the regulatory CXXC motif of human mitochondrial branched chain aminotransferase enzyme. Biochemistry 2004, 43 (23), 7356-7364.
42. Resnick, W. Multistage Reactors for predicting catalyst utilization with continuous replacement. Ind. Eng. Chem. 1960, 52 (10), 865-867.
43. Teves, H.; Waniek, T.; Pietzsch, M.; Syldatk, C.; Reuss, M. Application of different polarimetric methods for the analysis of enzyme-catalyzed enantioselective reactions. Anal. Bioanal. Chem. 1999, 363 (8), 738-743.
44. Bommarius, A. S. R.; Bettina R. Biocatalysis: Fundamentals and Applications, 1st ed.; Wiley-VCH: Weinheim; Cambridge, 2004; p 122.
45. Boersma, J. G.; Vellenga, K.; Wilt, H. G. d.; Joosten, G. E. Mass-transfer effects on the rate of isomerization of D-glucose into D-fructose, catalyzed by whole-cell immobilized glucose isomerase. Biotechnol. Bioeng. 1979, 21, (10), 1711-1724.
46. Straatsma, J.; Vellenga, K.; Wilt, H. G. J. D.; Joosten, G. E. H. Isomerization of glucose to fructose. 2. Optimization of reaction conditions in the production of high fructose syrup by isomerization of glucose catalyzed by a whole cell immobilized glucose isomerase catalyst. Ind. Eng. Chem. Process Des. Dev. 1983, 22 (3), 356-361.
47. Lee, C. Y.; Zeikus, J. G. Purification and characterization of thermostable glucose isomerase from Clostridium thermosulfurogenes and Thermoanaerobacter strain B6A. Biochem. J. 1991, 273 (Pt 3), 565-71.
48. Fersht, A. Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding; W. H. Freeman: New York, 1999; p 631.
49. Polakovic, M.; Vrabel, P. Analysis of the mechanism and kinetics of thermal inactivation of enzymes: Critical assessment of isothermal inactivation experiments. Process Biochem. 1996, 31 (8), 787-800.